Modeling by threading (Tito software) Unconserved sides chains calculation (Scwrl software) Evaluation (QMean software) Input alignment information: Query sequence MDSLATTFDEIRDAYAL-GRSGPPRQV----GERVWHLPTDDGGVAVKLYAS------GHH----ARAAKEAAV-LAHFETHGDTRFHVQALKRTATGEP--------LWTGANA--HAM-LTRWETGQFRTYDTFSPAEWDALGASLGALHLS------------LEQLHLPEVETIRARLT---AINADAVRRSLLDALDRARSN------------------HSAENLRRYVDLALR-----MLDRYYP-----GSINAFPAD--DPQ-----------YPIH----ND-----YNQFNYLFTGTL--PPL-------ILD--WEASI---GAPREYELVRCLNHLPLEAPHLAE--------AFVLAYRRTRRIDPARIAWAVDAACLQHALKLWIVQ-GWLDDPSRFASHLNGAVTMASAMVDARDRLVDFFSRCMEAGR 2DKB Chain:? ((3-433)) LNDDATFWRNARHHLVRYGGTFEPMIIERAKGSFVY---DADGRAILDFTSGQMSAVLGHCHPEIVSVIGEYAGKLDHLFSEMLSRPVVDLATRLANITPPGLDRALLLSTGAESNEAAIRMAKLVTGKYEIV-GFAQSWH---GMTGAAASATYSAGRKGVGPAAVGSFAIPAPFTYRPRFERNGAYDYLAELDYAFDLIDRQSSGNLAAFIAEPILSSGGIIELPDGYMAALKRKCEARGMLLILDEAQTGVGRTGTMFACQRDGVTPDILTLSKTLGAGLPLAAIVTSAAIEERAHELGYLFYTTHVSDPLPAAVGLRVLDVVQRDGLVARANVMGDRLRRGLLDLMERFDCIGDVRGRGLLLGVEIVKDRRTKEPADGLGAKITRECMNLGLSMNIVQLPGMGGVFRIAPPLT--VS-----EDEIDLGLSLLGQAIERAL

General information: TITO was launched using: RESULT: Template: 2DKB.pdb Alignment : align.pir Tito was launched with SMD and SCWRL Tito text output Monomeric PKB - chain A - contact count / total energy / energy per contact / energy per residue : 1637 -40761 -24.90 -128.99 target 2D structure prediction score : 0.59 Monomeric hydrophicity matching model chain A : 0.64 3D Compatibility (PKB) : -24.90 2D Compatibility (Sec. Struct. Predict.) : 0.59 1D Compatibility (Hydrophobicity) : 0.64 QMean score : 0.218

(partial model without unconserved sides chains): PDB file : Tito_2DKB.pdb: (Unconserved sides chains are recalculated) : Sequence: align-2dkb-query.scw PDB file : Tito_Scwrl_2DKB.pdb: