Modeling by threading (Tito software) Unconserved sides chains calculation (Scwrl software) Evaluation (QMean software) Input alignment information: Query sequence MRSEALEQFVVEEAGVGAPRGASWSRVDEGQGANRVWRVRWGPGSSVIVKRCGPGRAFVQERRAATRWAPAVADASRGLGHARVLAASQALRCLVFVDA-GR-GEEQVA--LSPAAFACAGRYLARLHALPVDERDPVPLVEALARREARWLEGAPE---LR---AVASSLGPGALAD--A-DWGPRVPCHRDFQPDNWLWDGRTLTVVDFEHARPDARALDLAKLWTRLDGDVDARANAAFWSAYLGPEPCSPSFLAQLRAGLVLHGLASVAWGRSH---D--DEAFVAEGERAVALARSGREPPNPRAGTPLASL 3DXQ Chain:A ((2-288)) -MTDEARAKLAAIPMLAG--YTGPLERL-GGLTNLVFRA----G-DLCLRIPGK----YINRANEAVAAREAAKAG--VS-PEVLHVDPATGVMVTRYIAGAQTMSPEKFKTRPGSPARAGEAFRKLHGSGAVFPFRF----ELFAMIDDYLKVLS-NVTLPAGYHDVVRE-AGGVRSALAAHPLPLAACHCDPLCENFLDTGERMWIVDWEYSGMNDPLWDLGDLSVEG--KFNANQDEELMRAYFGGEA-RPAERGRVVIYKAMCDLLWTLWGLIQLANDNPVDDFRAYADGRFARCKALMETP-----------

General information: TITO was launched using: RESULT: Template: 3DXQ.pdb Alignment : align.pir Tito was launched with SMD and SCWRL Tito text output Monomeric PKB - chain A - contact count / total energy / energy per contact / energy per residue : 1219 -31308 -25.68 -119.04 target 2D structure prediction score : 0.64 Monomeric hydrophicity matching model chain A : 0.67 3D Compatibility (PKB) : -25.68 2D Compatibility (Sec. Struct. Predict.) : 0.64 1D Compatibility (Hydrophobicity) : 0.67 QMean score : 0.364

(partial model without unconserved sides chains): PDB file : Tito_3DXQ.pdb: (Unconserved sides chains are recalculated) : Sequence: align-3dxq-query.scw PDB file : Tito_Scwrl_3DXQ.pdb: