Modeling by threading (Tito software) Unconserved sides chains calculation (Scwrl software) Evaluation (QMean software) Input alignment information: Query sequence KLCKWTVLNSEGEIIDSGSCLNTEYMKHGDIHVEFENDCTPIIFGADRVAEKVTIKG 5Y97 Chain:C ((45-93)) ---KWT-FHSDGTVRSLGKCLATNNSKFGNLVVIY--DCSKL--AAEDISWDVSVGG

General information: TITO was launched using: RESULT: Template: 5Y97.pdb Alignment : align.pir Tito was launched with SMD and SCWRL Tito text output Monomeric PKB - chain C - contact count / total energy / energy per contact / energy per residue : 136 -14414 -105.98 -294.15 target 2D structure prediction score : 0.57 Monomeric hydrophicity matching model chain C : 0.75 3D Compatibility (PKB) : -105.98 2D Compatibility (Sec. Struct. Predict.) : 0.57 1D Compatibility (Hydrophobicity) : 0.75 QMean score : 0.210

(partial model without unconserved sides chains): PDB file : Tito_5Y97.pdb: (Unconserved sides chains are recalculated) : Sequence: align-5y97-query.scw PDB file : Tito_Scwrl_5Y97.pdb: