Modeling by threading (Tito software) Unconserved sides chains calculation (Scwrl software) Evaluation (QMean software) Input alignment information: Query sequence MVKSPDLPVLPGSDQVAPASAIWSSETWRWEAVRWMDTALARRGLERVPTTPLQPRVRPWSTVLVAETTDQGRVWFKATSP--EMSPEAAILRALRSVTPDAVPVVWADDPERGWLLMPD-QGP-VLRDVQRDDDAVSLMSSVVRRYARLQRSSTRVVDQLRD-AGVPDMSPRESARRWQRL--GLKP---DTTREVRRAAQRLDAVGLPLTIQHDDLHAGNVFADGTSAGAHDARIFDWGDASVGNPLCSLLVPLERIGEGLDDDAARAARERILRAYLSVWSDVVSSTALSAAVDDALLIARVGRVFTWQRALTRASADERHAWGVHGRRLIAEINRSLGHAPEPSHD 3DXQ Chain:A ((28-286)) ---------------------------------------------------------GLTNLVFRAG-----DLCLRIPGKYINRANEAVAAREAAKAG-VS-PEVLHVDPATGVMVTRYIAGAQTMSPEKF-----KTRPGSPARAGEAFRKLHGSGAVFPFRFELFA-MIDDYLKVLS--NVTLPAGYHDVVREAGGVRSALAAHPLPLAACHCDPLCENFLDTG-----ERMWIVDWEYSGMNDPLWDLGDLSVEGKFN------ANQDEELMRAYFGGEA----RPAERGRVVIYKAMCDLLWTLWGLIQLAN--DNPVDDFRAYADGRFARCKALME--------

General information: TITO was launched using: RESULT: Template: 3DXQ.pdb Alignment : align.pir Tito was launched with SMD and SCWRL Tito text output Monomeric PKB - chain A - contact count / total energy / energy per contact / energy per residue : 1117 16345 14.63 67.26 target 2D structure prediction score : 0.72 Monomeric hydrophicity matching model chain A : 0.61 3D Compatibility (PKB) : 14.63 2D Compatibility (Sec. Struct. Predict.) : 0.72 1D Compatibility (Hydrophobicity) : 0.61 QMean score : 0.373

(partial model without unconserved sides chains): PDB file : Tito_3DXQ.pdb: (Unconserved sides chains are recalculated) : Sequence: align-3dxq-query.scw PDB file : Tito_Scwrl_3DXQ.pdb: