Modeling by threading (Tito software) Unconserved sides chains calculation (Scwrl software) Evaluation (QMean software) Input alignment information: Query sequence LKPRFTLAEAKAMARDEFHV----------RVAAIVELN-SYDDQNYKVTAENGAVYVLKVHNGVES-------RDEGLLDAQSQLYERLRRK-GVAAPYPVDSNPLADGDATFALRLLEWVDG-DL-LSSKE----ITPGLLATTGAFLGRIRLALDDFDHAALH---RVHLWD-GRQFPAL------------ASFADGLVDAGCDV---D--KAADVHRAIANFDAVVAPAAAQLPLATLHGDFNDANVLVGAETLGVLDIGDSVHSWRVNDVAVGMAYVVV 2PYW Chain:A ((8-276)) ---PLNEKSLVDYIKSTPALSSKIGADKSDDDLVIKEVGDGNLNFVFIVVG-SSGSLVIKQALPYIRCIGESWPMTKERAYFEATTLRKHGNLSPDHVPEVYHFD------RTMALIGMRYLEPPHIILRKGLIAGIEYPFLADHMSDYMAKTLFFTSLLYHDTTEHRRAVTEFCGNVELCRLTEQVVFSDPYRVSTFNRWT-SPYLDDDAKAVREDSALKLEIAELK----SMFCERAQALIHGDLHTGSVMVTQDSTQVIDPEFSFYGPMGFDIGAYLGNLI-

General information: TITO was launched using: RESULT: Template: 2PYW.pdb Alignment : align.pir Tito was launched with SMD and SCWRL Tito text output Monomeric PKB - chain A - contact count / total energy / energy per contact / energy per residue : 726 -14504 -19.98 -65.04 target 2D structure prediction score : 0.66 Monomeric hydrophicity matching model chain A : 0.63 3D Compatibility (PKB) : -19.98 2D Compatibility (Sec. Struct. Predict.) : 0.66 1D Compatibility (Hydrophobicity) : 0.63 QMean score : 0.282

(partial model without unconserved sides chains): PDB file : Tito_2PYW.pdb: (Unconserved sides chains are recalculated) : Sequence: align-2pyw-query.scw PDB file : Tito_Scwrl_2PYW.pdb: