Modeling by threading (Tito software) Unconserved sides chains calculation (Scwrl software) Evaluation (QMean software) Input alignment information: Query sequence MGLRKTYAKPYSRGISSPLEALRISPVVLSALKGLLSPDTLSRLTPL-GGFEARVYTD---G-----------ERVYKVYQPGEA--HLAALEAERM---ARAGLGSFVLGVAQVEGQGILVIRHFPGKPFSPESF-TPKALAALSHLFLSLHRLPEPGYV-ERE----ELSERLERFAESLGSVP-------EAL---SLIKALMREVTW-----VAGVEKRFCHRDAWAGNLLLKTQENPSHDDPEVLLVDWVRSGGDDPARDLALLKTGS-LDLL-----------GEKRAREALFRLVQFYPK-E-------------VRERLAFYVPLTYLHDLHWFRTKKP------E-GFLEALADKLPRALSFFQDCFPLRNRAC 3C5I Chain:D ((34-355)) ---------------------------------------DNLRVKQIL--LTNQLFEVGLKEETANNYNSIRTRVLFRIYGKHVDELYNTISEFEVYKTMSKYKIAPQLLNTFN----GGRIEEWLYGDPLRIDDLKNPTILIGIANVLGKFHTLSRKRHLPEHWDRTPCIFKMMEKWKNQLFKYKNIEKYNCDIHKYIKESDKFIKFMKVYSKSDNLANTIVFCHNDLQENNIINTNK--------CLRLIDFEYSGFNFLATDIANFFIETSIDYSVSSYPFFEIDKKKYISYENRKLFITAYLSNYLDKVVPTPKLIDEILEAVEVQALGAHLLWGFWSIIRGYQTKSYNEFDFFLYAEQRLKMYDDQ------------

General information: TITO was launched using: RESULT: Template: 3C5I.pdb Alignment : align.pir Tito was launched with SMD and SCWRL Tito text output Monomeric PKB - chain D - contact count / total energy / energy per contact / energy per residue : 867 -24703 -28.49 -101.24 target 2D structure prediction score : 0.64 Monomeric hydrophicity matching model chain D : 0.60 3D Compatibility (PKB) : -28.49 2D Compatibility (Sec. Struct. Predict.) : 0.64 1D Compatibility (Hydrophobicity) : 0.60 QMean score : 0.349

(partial model without unconserved sides chains): PDB file : Tito_3C5I.pdb: (Unconserved sides chains are recalculated) : Sequence: align-3c5i-query.scw PDB file : Tito_Scwrl_3C5I.pdb: