Modeling by threading (Tito software) Unconserved sides chains calculation (Scwrl software) Evaluation (QMean software) Input alignment information: Query sequence MPFRSNNPITRDELLSRFFPQF--HPVTTFNSGLSGGSFLIEHQ-GQRFVVRQPHDPDAPQSAFLRQYRALSQLP-ACI---APKPHLY-----LRDWMVVDYLPGEVK-------------TYLPDTNELAGLLYYLHQQPRFGWR-IT-----LLPLLELYWQQSDPAR-RTVGWLRMLKRLRKAR---EPRPLRLSPLHMDVHAGNLVHSV-SG-LKLIDWEYAGDGDIALELAAVWVENT-EQHRQLVNDYATRAKIYPAQLWRQVRRWFPWLLMLKAGWFEYRWRQTGDQQFIRLADDTWRQLLIKQ 5UXA Chain:A ((2-298)) --SKDIKQVI--EIAKKHNLFLKEETIQFNESGLDFQAVFAQDNNGIDWVLRLPRREDV-MPRTKVEKQALDLVNKYAISFQAPNWIIYTEELIAYKKLDGVPAGTIDHNIGNYIWEIDINNVPELFHKSLGRVLAELHSIPSNKAAALDLVVHTPEEARMSMKQRMDAVRAKFGVGENLWNRWQAWLNDDDMWPKKTGLIHGDVHAGHTMIDKDANVTGLIDWTEAKVTDVSHDFIFNYRAFGEEGLEALILAYKEIGGYYWPKMKEHIIELNAAYPVSIAEFAL----VSGIEEYEQMAKEALE------

General information: TITO was launched using: RESULT: Template: 5UXA.pdb Alignment : align.pir Tito was launched with SMD and SCWRL Tito text output Monomeric PKB - chain A - contact count / total energy / energy per contact / energy per residue : 1078 9178 8.51 35.43 target 2D structure prediction score : 0.59 Monomeric hydrophicity matching model chain A : 0.64 3D Compatibility (PKB) : 8.51 2D Compatibility (Sec. Struct. Predict.) : 0.59 1D Compatibility (Hydrophobicity) : 0.64 QMean score : 0.357

(partial model without unconserved sides chains): PDB file : Tito_5UXA.pdb: (Unconserved sides chains are recalculated) : Sequence: align-5uxa-query.scw PDB file : Tito_Scwrl_5UXA.pdb: