Modeling by threading (Tito software) Unconserved sides chains calculation (Scwrl software) Evaluation (QMean software) Input alignment information: Query sequence ------------------------------------MEKLVKANLRRKEQAFIDVVSPLLQDVGINPSLVQGIDVKVGRNQSAVLEVDGNQQYFVKLIQGSDGVARFRRSKDFENWVINKSIKFATPKLLAFS-KDQ-----RALMFEFARCDTNLGEMLGDKFIDSVTAMKVAVAIGSLHTSTVSISDNIESDLPVLPPQFPGLISLDY-FENATIGERNLWRILQNDAEL-------------LEALDLLVDSRINFVPIHGDFRPDQVFFRADEVV-LLD--FEEFRLGDPAR---------DLGSFIGDLFYHKMSWIAVGAQGTDGRLTHESLLERGVDLLGQV--RPII--QSFWEKYCIFCCGAQSETWKMTQ-PNLANRVT--GY-----AGWHL--------FDRSLARSALSGRLTANDRA-LNGIGRNL---IINSGMFAQEL-----GLGE----------------------------------------- 1NOU Chain:A ((6-503)) ALWPLPLSVKMTPNLLHLAPENFYISHSPNSTAGPSCTLLEEAFRRYHGYIFGTQVQQLL--VSITLQSECDAFPNISSDESYTLLVKEP----VAVLKANRVWGALRGLETFSQLVYQDS--YGTFTINESTIIDSPRFSHRGILIDTSRH-----------YLPVKIILKTLDAMAFNKFNVLHWHIVDDQSFPYQSITFPELSNKGSYSLSHVYTPNDVRMVIEYARLRGIRVLPEFDTPGHTLSWGKGQKDLLTPCY--SLDSFGPINPTLNTTYSFLTTFFKEISEVFPDQFIHLGGDEVEFKCWESN--PKIQDFMRQKGFGTDFKKLESFYIQKVLDIIATINKGSIVWQEVFDDKAKL-APGTIVEVWKDSAYPEELSRVTASGFPVILSAPWYLDLISYGQDWRKYYKVEPLDFGGTQKQKQLFIGGEACLWGEYVDATNLTPRLWPRASAVGERLWSSKDVRDMDDAYDRLTRHRCRMVERGIAAQPLYAGYCN

General information: TITO was launched using: RESULT: Template: 1NOU.pdb Alignment : align.pir Tito was launched with SMD and SCWRL Tito text output Monomeric PKB - chain A - contact count / total energy / energy per contact / energy per residue : 1796 22312 12.42 65.24 target 2D structure prediction score : 0.49 Monomeric hydrophicity matching model chain A : 0.62 3D Compatibility (PKB) : 12.42 2D Compatibility (Sec. Struct. Predict.) : 0.49 1D Compatibility (Hydrophobicity) : 0.62 QMean score : 0.246

(partial model without unconserved sides chains): PDB file : Tito_1NOU.pdb: (Unconserved sides chains are recalculated) : Sequence: align-1nou-query.scw PDB file : Tito_Scwrl_1NOU.pdb: