Modeling by threading (Tito software) Unconserved sides chains calculation (Scwrl software) Evaluation (QMean software) Input alignment information: Query sequence MTETLTKELAVTKALELPFWKAPSNAEILGGGITNFNVKITDEGRTYVVRLGEDIVEHGVMRFNELSACRAAHAAGVAPAVRYFQK--GALVQDYIPAD-PLVEEEIQ-QLKMLELIAALLGKVHRDATQLIRGPVLAFWVFHILRDYTETLRLLDSDHISKLDDLMQKAQKLEAA--VGNVHLVLCHNDLLPANILNENGRLWLVDWEYAGMNSPLFDLGGLATNAGLSEGLQKLLLETYFDTPVSDELWERYNAMKCASLLRESMWSMVSEQTSKIQFDYADYTRENLLRFERAFAELQLK 3DXQ Chain:A ((2-288)) -----MTDEARAKLAAIPMLAGYTGPLERLGGLTNLVFRA----GDLCLRIPGK----YINRANEAVAAREAAKAGVSPEVLHVDPATGVMVTRYIAGAQTMSPEKFKTRPGSPARAGEAFRKLHGSGAVFPF----RFELFAMIDDYLKVLS--NVTLPAGYHDVVREAGGVRSALAAHPLPLAACHCDPLCENFLDTGERMWIVDWEYSGMNDPLWDLGDLSVEGKFNANQDEELMRAYFGGEARPAERGRVVIYKAMCDLLWTLWGLIQLANDNPVDDFRAYADGRFARCKALMETP---

General information: TITO was launched using: RESULT: Template: 3DXQ.pdb Alignment : align.pir Tito was launched with SMD and SCWRL Tito text output Monomeric PKB - chain A - contact count / total energy / energy per contact / energy per residue : 1320 -18183 -13.78 -66.12 target 2D structure prediction score : 0.64 Monomeric hydrophicity matching model chain A : 0.71 3D Compatibility (PKB) : -13.78 2D Compatibility (Sec. Struct. Predict.) : 0.64 1D Compatibility (Hydrophobicity) : 0.71 QMean score : 0.449

(partial model without unconserved sides chains): PDB file : Tito_3DXQ.pdb: (Unconserved sides chains are recalculated) : Sequence: align-3dxq-query.scw PDB file : Tito_Scwrl_3DXQ.pdb: