Modeling by threading (Tito software) Unconserved sides chains calculation (Scwrl software) Evaluation (QMean software) Input alignment information: Query sequence MPRPGGPGRCSIRQRSVACTGAGAQRDVSAARSPVPNPATSAVIPAILADVEEVAVVVAHHDCATLRVGDVFLKVDADQTRTDVEVEAMAR-APIPTPRVLWRK--------------PPVLALAALPGTALGRLGEPSTASSAAWVAAGAAVRKLHDAPLPPWPGR--S-RDEITSHLDHECEW----LITT--GVLP----SELVTRNRQVAEAAL-RPWTPVFTHGDLQTSHVFVDGD---EATGVIDWSEAAQGDALFDLATLTLGH------QEHLGDVVAGYGA--DV---DLDVIRAWWSLRSLRAVRWLIEHGFDPSAPGCEIDVLRSQL 6EF6 Chain:A ((64-318)) -------------------------------------------------------------HQSILRVHRQDYHQPHEIESELDWLAALRTDSDVTVPTVVPARDGRRVVTVDPADVPRHVVHFEMVGGAEPDEESL----TLDDFQTLGRITASLHEHSQRWTRPAGFGRFSWDWEHCLGDTPRWGRWQDAEGVGASETALLTRAQDLLHRKLEEYGSGPDRYGLIHADLRLANLLVDSSTPQRTITVIDFDDCGFGWYFYDFGTAVSFIEHDPRLGEWQESWVAGYRSRRELPAADEAMLPSFVFLRRLLLLAWM---------------------

General information: TITO was launched using: RESULT: Template: 6EF6.pdb Alignment : align.pir Tito was launched with SMD and SCWRL Tito text output Monomeric PKB - chain A - contact count / total energy / energy per contact / energy per residue : 801 -6670 -8.33 -31.91 target 2D structure prediction score : 0.63 Monomeric hydrophicity matching model chain A : 0.61 3D Compatibility (PKB) : -8.33 2D Compatibility (Sec. Struct. Predict.) : 0.63 1D Compatibility (Hydrophobicity) : 0.61 QMean score : 0.237

(partial model without unconserved sides chains): PDB file : Tito_6EF6.pdb: (Unconserved sides chains are recalculated) : Sequence: align-6ef6-query.scw PDB file : Tito_Scwrl_6EF6.pdb: