Modeling by threading (Tito software) Unconserved sides chains calculation (Scwrl software) Evaluation (QMean software) Input alignment information: Query sequence --MQQQSFYENTVPIAISQLRNDRQIPTLCQYFDGGQCRVFKVTFTD-GESWAVRVPL--FVRHASQNTVIQLLESEARILRELEVKEFSWAARLRGCSFTFDNAIRYPFIALTWIPGSQLLWSDDFPTRPLRDKILDQVATMHISLIECSKE-ARGSSLKHFTRIIQNKTRRVREGLLPEITEQDCSDQMNILPNVL--LPELDEAPFAITHGDISPQNILIDAHHN---VTGIIDWGFSSRVP---FQQAACF------PRFLQLQNI----DLW--------------PNSTLQKDRETYITSVRCRAPLEVSSMMIQVLSSENADFQHCFLESIISKGM-HRRLARNGWGVSSCGQGSEGEANDRNL 1JKS Chain:A ((2-294)) TVFRQENVDDY---YDTGE--------ELGS---GQFAVVKKCREKSTGLQYAAKFIKKRRTKSSRRGVSREDIEREVSILKEI----------------------QHPNVI-------TLHEVYENKT--------------DVILIL---ELVAGGE--LFDFLAEKES----------LTEEEATEFLKQILNGVYYLHSLQ-----IAHFDLKPENIMLLDRNVPKPRIKIIDFGLAHKIDFGNEFKNIFGTPEFVAPEIVNYEPLGLEADMWSIGVITYILLSGASPFLG-DTKQETL-ANVS-AVNYEFEDEYFSNTSALAKDFIRRLLVKDPKKRMTIQDSLQHPW-----IKPPQFE------

General information: TITO was launched using: RESULT: Template: 1JKS.pdb Alignment : align.pir Tito was launched with SMD and SCWRL Tito text output Monomeric PKB - chain A - contact count / total energy / energy per contact / energy per residue : 1156 28154 24.35 116.82 target 2D structure prediction score : 0.61 Monomeric hydrophicity matching model chain A : 0.63 3D Compatibility (PKB) : 24.35 2D Compatibility (Sec. Struct. Predict.) : 0.61 1D Compatibility (Hydrophobicity) : 0.63 QMean score : 0.242

(partial model without unconserved sides chains): PDB file : Tito_1JKS.pdb: (Unconserved sides chains are recalculated) : Sequence: align-1jks-query.scw PDB file : Tito_Scwrl_1JKS.pdb: