Modeling by threading (Tito software) Unconserved sides chains calculation (Scwrl software) Evaluation (QMean software) Input alignment information: Query sequence MTETLTKELAVTKALE-LPFWKA----PSNAEILGGGITNFNVKITDEG----------RTYVVRLGEDIVEHGVMRFNELSACRAAHAAGVAPAVRYFQKGALVQDYIPADPLVEEEIQQLKMLELIAALLGKVHRDATQLIRGPVL--AFWVFHILRDYTETLRLLD------SDHI---SKLDDLMQKAQKLEA-AVGNVHLVLCHNDLLPANILNENGRLWLVDWEYAGMNSPLFDLGGLATNAGL------------------SEGLQKLLLETYFDTPV-----S----DELWERYNAMKCASLLRESMWSMVSEQTS--KIQFDYADYTRENLLRFERAFAELQLK 3C5I Chain:D ((12-358)) ----TDPLYIKKICLEKVPEWNHFTEDNLRVKQIL--LTNQLFEVGLKEETANNYNSIRTRVLFRIYGKHVDELYNTISEFEVYKTMSKYKIAPQLLNTFNGGRIEEWLYGDPLRIDDLKNPTILIGIANVLGKFHTLSRKRHLPEHWDRTPCIFKMMEKWKNQLFKYKNIEKYNCDIHKYIKESDKFIKFMKVYSKSDNLANTIVFCHNDLQENNIINTNKCLRLIDFEYSGFNFLATDIANFFIETSIDYSVSSYPFFEIDKKKYISYENRKLFITAYLSNYLDKVVPTPKLIDEILEAVEVQALGAHLLWGFWSIIRGYQTKSYNEFDFFLYAEQRLKMYDDQKEY----

General information: TITO was launched using: RESULT: Template: 3C5I.pdb Alignment : align.pir Tito was launched with SMD and SCWRL Tito text output Monomeric PKB - chain D - contact count / total energy / energy per contact / energy per residue : 1117 -13511 -12.10 -47.08 target 2D structure prediction score : 0.62 Monomeric hydrophicity matching model chain D : 0.68 3D Compatibility (PKB) : -12.10 2D Compatibility (Sec. Struct. Predict.) : 0.62 1D Compatibility (Hydrophobicity) : 0.68 QMean score : 0.486

(partial model without unconserved sides chains): PDB file : Tito_3C5I.pdb: (Unconserved sides chains are recalculated) : Sequence: align-3c5i-query.scw PDB file : Tito_Scwrl_3C5I.pdb: