Modeling by threading (Tito software) Unconserved sides chains calculation (Scwrl software) Evaluation (QMean software) Input alignment information: Query sequence MSVEVNSEETVPEVLLLDLGGITFPSPIGPLLAAAESIRDPGLPRRMVSSVLWKELECGFLTIPEFCEQFAKGKAVVQEALIGWFEGLRAMEPSPRMIILLSELRLKYPGLKIGAVTNNFKHPAPLRPMRDLRGELLFDTIVESAVEGMAKGHPGGERWALVEVWNFHDGSYMEAHIIWSSVRLFKTALERLD---YHGPASAVLYLDDLKHNLAQPASLGIRTRHAITPEEATETIRKMLALDVSSGSPLQKYLASLGVLPDSISDQARPFAWQFSFGQSNPTYLVGLIPEKPLEGYTLQKLLEEKCAVLRKQPPGELLPSAHDVVREYTVMSELGKEGCVPVPRTLGLCTDKTICGAAFYVMRFVTGVVFTDPNLPNLQPYQRRKVYEDLMKTAAAVHNFPWHRSEALTQRFRGDPSKYVSKQVERWSTQGIDVE-----------------GFKRLAKGLLDNVKISQKSPEFQSLVHGDFRLDNCIYDPHTFEVVAVLDWELSTTGNSLVDIASALSQYYGLYPGIAQLSSNFEELGIPK---ERELLDLYLRYREV---ESIPEGLMQYMEAFQCLRMAGILYGVLMRTKKGNASQQHQQAKGGSIFSMAYVTKLCTRGLELLQSRACSSSPIAVDAPSKL 1NW1 Chain:A ((32-426)) ---------------------------------------------------------------------------------------------------------------------------------------------------------------GMKELLSTMDLDTDANTIPELKERAHMLCARFLGGAWKTVPLEH-------------------------------------------------------------------LRISRIKGGMSNMLFLCRLSEVYPPIR------NEPNKVLLRVYFNPE---TESHLVAESVIFTLLSERHL--GPKLYGIFSG-------GRLEEYIPSRPLSCHEISL------AHMSTKIAKRVAKVHQLEV---------PIWKEPDYLCEALQRWLKQLTGTVDAEHRFDLPEECGVSSVNCLDLARELEFLRAHISLSKSPVTFCHNDLQEGNILLPKRLV----LIDFEYASYNYRAFDFANHFIEWTIDYDIDEAPFYKIQTENFPENDQMLEFFLNYLREQGNTRENELYKKSEDLVQETLPFVPVSHFFWGVWGLLQVELSPVGFGFADYGRDRLSLYFKH----KQLLKNLA--------------

General information: TITO was launched using: RESULT: Template: 1NW1.pdb Alignment : align.pir Tito was launched with SMD and SCWRL Tito text output Monomeric PKB - chain A - contact count / total energy / energy per contact / energy per residue : 1595 -27766 -17.41 -81.91 target 2D structure prediction score : 0.65 Monomeric hydrophicity matching model chain A : 0.57 3D Compatibility (PKB) : -17.41 2D Compatibility (Sec. Struct. Predict.) : 0.65 1D Compatibility (Hydrophobicity) : 0.57 QMean score : 0.169

(partial model without unconserved sides chains): PDB file : Tito_1NW1.pdb: (Unconserved sides chains are recalculated) : Sequence: align-1nw1-query.scw PDB file : Tito_Scwrl_1NW1.pdb: