Modeling by threading (Tito software) Unconserved sides chains calculation (Scwrl software) Evaluation (QMean software) Input alignment information: Query sequence --------------------------------------------------MEEALAR--------HDRFGEDFSKVFTIINSAEIPAVEN-----SALYLFVGTSR-APDEASKYVRDRVAQNAQSSTLEETLH---------------SIHEELK----ILSKKMT--REDPMNLDPEIEAALYERDGGCCFITG-------------RTAGVQP--IYIIPPSI---LEDKDLQPGGYLRPLLEVSLTKEG---------TEQMLNL-----------LGL--PGRENVLKNLILMEPSIRYSFRHGYFEIIKSPYLEPPYLP----------TDAPKSKNGGWWLQPIAPQSEVPQIIPRNNELYKVPSTINPISHPL---PARLLLK--THGIVSHPLHTIYIEEQIKAGWPVEPEPKELNWVGRLLLQILLRLIPNFARIRLYELIYK-----------MVDYWDPSQKGSH------VKFLPLGLVLKKGRENTE---NEAKALTLAEQYISISTPRLIDSVMVNKTSGFILMTKVVGRSLSSILHRITWEELEQIGKDLANFITELRRIPNSSKYLIADTRGGPISDHRFFYQTWGPFKTVSGFTDRLLQ--------DVKGARDKPPLSFLYEKKHKVYFTHS-----DIHMTNLFVTCGRLSGVVDWENAGFKPEYWEYIRAMWAYGADKHAKCLYGSAFGDKYKEEGGIEITAVWIGFSLTTFSGFSGLIFEQLIRLRN-EYLPLAQGKISPDVNPGHLCSTAKTSYTSAFARWEAV-----PARPMPTSQSGPIT------AKDAFKG-- 1JRO Chain:B ((2-777)) SVGKPLPHDSARAHVTGQARYLDDLPCPANTLHLAFGLSTEASAAITGLDLEPVRESPGVIAVFTAADLPHD-NDASPAPSPEPVLATGEVHFVGQPIFLVAATSHRAARIAARKARITYAPRPAILTLDQALAADSRFEGGPVIWARGDVETALAGAAHLAEGCFEIGGQEHFYLEGQ--AALALPAEGGVVIHCSSQHPSEIQHKVAHALGLAFHDVRVEMRRMGGGFGGKESQGNHLAIACAVAAR-ATGRPCKMRYDRDDDMVITGKRHDFRIRYRIGADASGKLLGADFVHLARCGWSADLSLPVCDRAMLHADGSYFVPALRIESHRLRTNTQSN---TAFRGFGGPQG-----------ALGMERAIEHLARGMGRDPAELRALNFYDPPEKKTQTTHY-------GQEVADCV-----LGELVTRLQKSANFTTRRAEIAAWNSTNRTLARGIALSPVKFGISFTLTHLNQAGALVQIYTDGSVALNHGGTEMGQGLHAKMVQVAAAVLGIDPVQVRITATDTSKVPNTSATA--ASSGADMNGMAVKDACETLRGRLAGFVAAREGCAARDVIFD--------AGQVQASGKSWRFAEIVAAAYMARISLSATGFYATPKLSWDRLRGQGRPFLYFAYGAAITEVVIDRLTGENRIL--RTDILHDAGAS----LNPALDIGQIEGAYVQGAGWLTTEELV--WDHCGRLMT---------HAPSTYKIPAFSDRPRIFNVALWDQP----NREETIFRSKAVGEPPFLLGISAFLALHDACAACGPHWPDLQAPATPEAVLAAVRRAEGRA

General information: TITO was launched using: RESULT: Template: 1JRO.pdb Alignment : align.pir Tito was launched with SMD and SCWRL Tito text output Monomeric PKB - chain B - contact count / total energy / energy per contact / energy per residue : 3333 33055 9.92 57.69 target 2D structure prediction score : 0.54 Monomeric hydrophicity matching model chain B : 0.62 3D Compatibility (PKB) : 9.92 2D Compatibility (Sec. Struct. Predict.) : 0.54 1D Compatibility (Hydrophobicity) : 0.62 QMean score : 0.202

(partial model without unconserved sides chains): PDB file : Tito_1JRO.pdb: (Unconserved sides chains are recalculated) : Sequence: align-1jro-query.scw PDB file : Tito_Scwrl_1JRO.pdb: