Modeling by threading (Tito software) Unconserved sides chains calculation (Scwrl software) Evaluation (QMean software) Input alignment information: Query sequence MANPLDHKIKEYLRKLDPTILDIDN-IQSISTHKIGLGESNLNYLAIIN-GKKFNIRINMYPHFPKKSENEFNSLKIVEP-LGI-TPKVFHYEASKEILGETFIILEYLDGRSLNKYKK----------IGGDVIRKLGVAVAQLHNTNINNIENRLKRHGSSKMDLLNIIKQMIEYINRKRKHYFPIRGVFENVLEKSYKHLQRLNFPIKPSYVLGHGDIDPSNVISSQ-RKLKLIDWEDLGLMDPALEIVGLFDSFDLSNKEKELFLKGYLEVREDTSLKKKLPIFLPFQIFRVFCWAIMHIYELGEGETNEVFLKEQDLKEHIDYTEKMFTKCKKAEIIDKDVRWNISEIVPEHYLKLTT 5UXD Chain:A ((6-254)) --------DLDALLDL---AARHGLDLDGGTLRTEEIGLDFRVAFARAHDGGDWVLRLPRRPDVLERAAVEGRLLAMLAPHLDVAVPDWRIST-------SELIAYPLLPGSPGLTVAADGEVSWHVDMASTVYARSLGSVVAQLHAVDAEAAAATGIE-VRSPAQVRGAWRQDLARVGAEF----EIA---PALRERWEAWLADDG-CWPGHSVLTHGELYPAHTLVEDERITAVLDWTTAAVGDPAKDLMFHQVS--APSAIFEVALQAYAEGGGR-------------------------------------------------------------------------------------

General information: TITO was launched using: RESULT: Template: 5UXD.pdb Alignment : align.pir Tito was launched with SMD and SCWRL Tito text output Monomeric PKB - chain A - contact count / total energy / energy per contact / energy per residue : 934 7284 7.80 31.13 target 2D structure prediction score : 0.66 Monomeric hydrophicity matching model chain A : 0.61 3D Compatibility (PKB) : 7.80 2D Compatibility (Sec. Struct. Predict.) : 0.66 1D Compatibility (Hydrophobicity) : 0.61 QMean score : 0.305

(partial model without unconserved sides chains): PDB file : Tito_5UXD.pdb: (Unconserved sides chains are recalculated) : Sequence: align-5uxd-query.scw PDB file : Tito_Scwrl_5UXD.pdb: