Modeling by threading (Tito software) Unconserved sides chains calculation (Scwrl software) Evaluation (QMean software) Input alignment information: Query sequence --------------------------------------------------MEEALARHDRFGEDFSKVFTIINSAEIPAVE--------NSALYLFV----GTSRAPDEASKYVRDRVAQNAQS--STLEETLHSIH----EELKIL-----SKKMTREDPMN-LDPEIEAALYERDG-GCCFITG--------------RTAGVQPIYII----------PPSILEDKDLQPGGYLRPLLEVSLTKEGTEQMLNL---LGLPGRENVLKNL----ILMEPSIRYSFRHGY----FEIIKSPYLEPP--------YLPTDAPKSKNGGWWLQPIAPQSE----------------------VPQIIPRNNELYKVPSTINPISHPLPARLLLKTHGIVSHPL--------------------HTIY----------IEEQIKA----GWPV---------------------------------------------------------EPEPKELNWVGRLLLQILLRLIPN--FARIRLYELIYKMVDYWDPSQKGSH----------VKFLPLGLVLKKGRENTENEAKALTLAEQYISISTPRLIDSV--MVNKTSGFILMTKVVGRSLSSILHRITWEELEQIGKDLANFITELRRIPNSSKYLIADTRGGPISDHRFFYQTWGPFKTVSGFTDRLLQDVKGARDKPPLSFLYEKKHKVYFTHSDIHMTNLFVTCGRLSGVVDWENAGFKPEYWEYIRAMWAYGADKHAKCLYGSAFGDKYKEEGGIEITAVWI-GFSLTTFSGFSGLIFEQLIRLRNEYLPLAQGKISPDVNPGHLCSTAKTSYTSAFA---RWEAVPA-----RPMPTSQSGPIT------AKDAFKG----------------------------------------------------------------------------------------------------------------------------------------------------------------------------- 1IWG Chain:A ((7-1036)) DRPIFAWVIAIIIMLAGGLAILKLPVAQYPTIAPPAVTISASYPGADAKTVQDTVTQ---------VIEQNMN--GIDNLMYMSSNSDSTGTVQITLTFESGTD--ADIAQVQVQNKLQLAMPLLPQEVQQQGVSVEKSSSSFLMVVGVINTDGTMTQEDISDYVAANMKDAISRTSGVGDVQLFGSQYAMRIWMNPNELNKFQLTPVDVITAIKAQNAQVAAGQLGGTPPVKGQQLNASIIAQTRLTSTEEFGKILLKVNQDGSRVLLRDVAKIELGGENYDIIAEFNGQPASGLGIKLATGANALDTAAAIRAELA-KMEPFFPSGLKIVYPYDTTPFVKISIHEVVKTLVEAIILVFLVMYLFLQNFRATLIPTIAVPVVL-LGTFAVLAAFGFSINTLTMFGMVLAIGLLVDDAIVVVENVERVMAEEGLPPKEATRKSMGQIQGALVGIAMVLSAVFVPMAFFGGSTGAIYRQFSITIVSAMALSVLVALILTPALCATMLKFGWFNRMFEKSTHHYTDSVGGILRSTGRYLVLYLIIVVGMAYLFVRLPSSFLPDEDQGVFMTMVQLPAGA---TQERTQKVLNEVTHYYLTKEKNNVESVFAVNGFGFAGRGQNTGIAFVSLKDWADR--PGEENKVEAITMRATRAFSQIKDAMVFAFNLPAIVELGTATGFDFELIDQAG-LGHEKLTQARNQLLAEAAKHPMLTSVRPNGLEDTPQ------FKIDIDQEKA------QALGV--SINDINTTLGAAW--------------------GGSYVNDFIDRGRVKKVYVMSEAKYRMLPDDIGDWYVRAADGQMVP------FSAFSSSRWEYGSPRLERYNGLPSMEILGQAAPGKSTGEAMELMEQLASKLPTGVGYDWSGNQAPSLYAISLIVVFLCLAALYESWSIPFSVMLVVPLGVIGALLAATFRGLTNDVYFQVGLLTTIGLSAKNAILIVEFAKDLMDKEGKGLIEATLDAVRMRLRPILMTSLAFILGVMPLVISTGAGSGAQNAVGTGVMGGMVTATVLAIFFVPVFFVVVRRRFSRK

General information: TITO was launched using: RESULT: Template: 1IWG.pdb Alignment : align.pir Tito was launched with SMD and SCWRL Tito text output Monomeric PKB - chain A - contact count / total energy / energy per contact / energy per residue : 2411 34170 14.17 59.63 target 2D structure prediction score : 0.55 Monomeric hydrophicity matching model chain A : 0.53 3D Compatibility (PKB) : 14.17 2D Compatibility (Sec. Struct. Predict.) : 0.55 1D Compatibility (Hydrophobicity) : 0.53 QMean score : 0.228

(partial model without unconserved sides chains): PDB file : Tito_1IWG.pdb: (Unconserved sides chains are recalculated) : Sequence: align-1iwg-query.scw PDB file : Tito_Scwrl_1IWG.pdb: