Modeling by threading (Tito software) Unconserved sides chains calculation (Scwrl software) Evaluation (QMean software) Input alignment information: Query sequence MTTLSVLFEQISP-YLPPQE----ALKVENIEDGYSNHVMKLHWYN---------APRAVLRVPMLDTEAFLIDRHAELNALKAAQNAGISPTVIWSNDQGAILSEYIHAPALSWDVKHNSRDIKRIGALFTQVHALSVNAPS---RN----IYQVIEHYVGGIEHHD-T---NGAHKHEVAYLQHCFDQMNKV---DSRGRPDVLCHNDLNPKNVLLNNEEIWFIDWEYTALGDPLFDLAAVSRSHNL------------------TLDQQKILIEAYDDTLN-----V----QDTLKTIHDYGFAYALREMAWLLLKHVISVDDHQSLDYYREFKDTKKLNPFI 3C5I Chain:D ((13-352)) --DPLYIKKICLEKVPEWNHFTEDNLRVKQIL--LTNQLFEVGLKEETANNYNSIRTRVLFRIYGKHVD-ELYNTISEFEVYKTMSKYKIAPQLLNTFN-GGRIEEWLYGDPLRIDDLKNPTILIGIANVLGKFHTLSRKRHLPEHWDRTPCIFKMMEKWKNQLFKYKNIEKYNCDIHKYIKESDKFIKFMKVYSKSDNLANTIVFCHNDLQENNIINTNKCLRLIDFEYSGFNFLATDIANFFIETSIDYSVSSYPFFEIDKKKYISYENRKLFITAYLSNYLDKVVPTPKLIDEILEAVEVQALGAHLLWGFWSIIRGYQTK---SYNEFDFFLYAEQRLKMY-

General information: TITO was launched using: RESULT: Template: 3C5I.pdb Alignment : align.pir Tito was launched with SMD and SCWRL Tito text output Monomeric PKB - chain D - contact count / total energy / energy per contact / energy per residue : 1097 12088 11.02 43.02 target 2D structure prediction score : 0.62 Monomeric hydrophicity matching model chain D : 0.70 3D Compatibility (PKB) : 11.02 2D Compatibility (Sec. Struct. Predict.) : 0.62 1D Compatibility (Hydrophobicity) : 0.70 QMean score : 0.417

(partial model without unconserved sides chains): PDB file : Tito_3C5I.pdb: (Unconserved sides chains are recalculated) : Sequence: align-3c5i-query.scw PDB file : Tito_Scwrl_3C5I.pdb: