Modeling by threading (Tito software) Unconserved sides chains calculation (Scwrl software) Evaluation (QMean software) Input alignment information: Query sequence MSLPRRPDADPAALLAGLDRSLAGLGLTEVGEGFDNIAYAVRSPSGARLLLRVSKVADPVERA----RVLTKDVALLEFANRHSSLTTNEVIAADAHAGALLLTEVTGRTADQIRPTDRVAFAATMATFLTRLHTAPVVEAALVTEMDPRSAAQ----WLVDTATAWAAVADRTPVTLRDRVDEFLV--GPAPSDVRRITFCHNDLGDEHVVLSEDGGHVRGVIDWSDAVLGDPARDLGLLTLDFGPGIVDALIDDYHGPTGADFRGRVLWFAATAGVEGLAWRLANARPWQVTADRLHDVLAVLA 5UXB Chain:A ((16-246)) ----------------GLDLDGGTLRTEEIGLDF-RVAFA-RAHDGGDWVLRLPRRPDVLERAAVEGRLLAMLAPHLDVAVPDWRISTSELIAYPLLPGSPGLTV----EVSWHVDMASTVYARSLGSVVAQLHAV-DAEAAAATGIEVRSPAQVRGAWRQDLARVGAEF--EIAPALRERWEAWLADDGCWPG---HSVLTHGELYPAHTLVEDE--RITAVLDWTTAAVGDPAKDLMFHQVSAPSAIFEVALQAY-------------------------------------------------

General information: TITO was launched using: RESULT: Template: 5UXB.pdb Alignment : align.pir Tito was launched with SMD and SCWRL Tito text output Monomeric PKB - chain A - contact count / total energy / energy per contact / energy per residue : 862 -31625 -36.69 -145.74 target 2D structure prediction score : 0.58 Monomeric hydrophicity matching model chain A : 0.70 3D Compatibility (PKB) : -36.69 2D Compatibility (Sec. Struct. Predict.) : 0.58 1D Compatibility (Hydrophobicity) : 0.70 QMean score : 0.291

(partial model without unconserved sides chains): PDB file : Tito_5UXB.pdb: (Unconserved sides chains are recalculated) : Sequence: align-5uxb-query.scw PDB file : Tito_Scwrl_5UXB.pdb: