Modeling by threading (Tito software) Unconserved sides chains calculation (Scwrl software) Evaluation (QMean software) Input alignment information: Query sequence MWQAVNRLLSECLGPAEIRERTELPGGDIHEAWR-LSYG-EKEVFVKCNTREMLPIFTAESDQLSLLARSKTVQVPEVYGVGSDRDYSFLLLEYIPLKPLDA----------HNAYCLGQQLAHLHQWSEQLQFGLDFDNDLATTPQPNSWQR-RWAQFFAEKRIGWQLQLAAEKGMSFGDIDDITNAVQERLQS-HQPQPSLLHGDLWPANCAASSN-----GPVIFDPA-CYWGDRECDLSMLPLYP------TLPAQIYDGYQSVWPLPIGFIERQSIYQLYYLLNRSNLFGGKHLINAQKAVDNLLHPEQFSL 3CSV Chain:A ((8-255)) ---EIRDFLAT-HGY-ADWNRTP--------RYQRLRSPTGAKAVLMDWSPEEGGDTQPFVDLAQYLRNL-DISAPEIYAEEH--ARGLLLIEDLGDALFTEVINNDPAQEMPLYRAAVDLLIHLHDAQTPE-LAR-L----DP-ETLSEMTRLAFSEYRYAI-----LG-----DAAEDNRKRFEHRFAQILSAQLEGDMVFVHRDFHAQNLLWLPEREGLARVGVIDFQDAKLGHRAYDLVSLLQDARRDVPAQVEAQMIDHYIQATGVDE--------------------------------------------

General information: TITO was launched using: RESULT: Template: 3CSV.pdb Alignment : align.pir Tito was launched with SMD and SCWRL Tito text output Monomeric PKB - chain A - contact count / total energy / energy per contact / energy per residue : 876 -991 -1.13 -4.63 target 2D structure prediction score : 0.63 Monomeric hydrophicity matching model chain A : 0.63 3D Compatibility (PKB) : -1.13 2D Compatibility (Sec. Struct. Predict.) : 0.63 1D Compatibility (Hydrophobicity) : 0.63 QMean score : 0.210

(partial model without unconserved sides chains): PDB file : Tito_3CSV.pdb: (Unconserved sides chains are recalculated) : Sequence: align-3csv-query.scw PDB file : Tito_Scwrl_3CSV.pdb: