Modeling by threading (Tito software) Unconserved sides chains calculation (Scwrl software) Evaluation (QMean software) Input alignment information: Query sequence MSGRALLNDTWAVVTTPRPIVDAVVR-SVCGRAVERLVPLAGGGLNETYRAEFAGDVAVVVRIARRPT--PWFIDEAHLMAQAAAA---GVPTAQVLGLEHLDHDGEPLSFSIQQFLPGRSLEE-LSGELPAFALERVVAEAGEILARVHSVVPDDQRGIQHELRLPDEHEVARVARIVATAL--GPA--AAAVVERGANFLRQEVTTRTAPPISLVHGDFCPKNLLIHD-GTVAGFIDWEFAGPASPAYDFAQ-WEVDAGEPLHDRVDLVRRGYARVADPGTADAGWTPAFAVDWSLEKLGWTNPAAPAQFRRCVDVIARYTVC 5IQC Chain:A ((7-281)) ------------DNATNVKAMKYLIEHYFDNFKVDSIEIIGSGYDSVAYLVN----NEYIFKTKFSTNKKKGYAKEKAIYNFLNTNLETNVKIPNIEYSYI----SDELSILGYKEIKGTFLTPEIYSTMSEEEQNLLKRDIASFLRQMHGLDYTDISECTIDN-K---QNVLEEYILLRETIYNDLTDIEKDYIESFMERLNAT-T-VFEGKKCLCHNDFSCNHLLLDGNNRLTGIIDFGDSGIIDEYCDFIYLLEDSEEEIGTNFGEDILRMYGNI--DIEKAKEYQDIVEEYYPIETIVY----------------------

General information: TITO was launched using: RESULT: Template: 5IQC.pdb Alignment : align.pir Tito was launched with SMD and SCWRL Tito text output Monomeric PKB - chain A - contact count / total energy / energy per contact / energy per residue : 1143 7367 6.45 28.12 target 2D structure prediction score : 0.55 Monomeric hydrophicity matching model chain A : 0.64 3D Compatibility (PKB) : 6.45 2D Compatibility (Sec. Struct. Predict.) : 0.55 1D Compatibility (Hydrophobicity) : 0.64 QMean score : 0.361

(partial model without unconserved sides chains): PDB file : Tito_5IQC.pdb: (Unconserved sides chains are recalculated) : Sequence: align-5iqc-query.scw PDB file : Tito_Scwrl_5IQC.pdb: