Modeling by threading (Tito software) Unconserved sides chains calculation (Scwrl software) Evaluation (QMean software) Input alignment information: Query sequence MNQIVEDAGSLDVFRWPSSSPPSPENLEHAARLCQGALGSTSVAVVATPYNHAGWSAQDCIK-VSFPSENRSFIAKVPRLVDENSATACKNEAQRASWASQHQIG-PAVIAIDDLSGAFAMEFLSGQTLSAQMM----LQDHLKTCTIGLLRRIHDAPSQHY--MQIYNAPAAVKR-MLQAADKERLLDGDDGLLLESLITWTFQKVGCQPTFQTLVPCHNDFHSQNIMLDQQ----GTLWAIDFEDCDLGDPMWDLGYLTANMGLE--PL--D-LAGIY-GCNME---Q-KKRLEVFYYLAIGHCAVWSAIHGPLWTQHYRDCMLRLRRGWLRL 3CSV Chain:A ((5-279)) -------------------------REDEIRDFLAT-HGYADWNR--TP----------RYQRLRSP-TGAKAVLMDWSPEEGG---DTQPFVDLAQYLRNLDISAPEIYAEEHARGLLLIEDLGDALFTEVINNDPAQEMPLYRAAVDLLIHLHDAQTPELARLDPE-TLSEMTRLAFSEYR-YAILGDAAEDNRKRFEHRFAQILSA-QLEGDMVFVHRDFHAQNLLWLPEREGLARVGVIDFQDAKLGHRAYDLVSLLQDARRDVPAQVEAQMIDHYIQATGVDESHFRSAYAVIAVQRNMRILGIFAR-----------------------

General information: TITO was launched using: RESULT: Template: 3CSV.pdb Alignment : align.pir Tito was launched with SMD and SCWRL Tito text output Monomeric PKB - chain A - contact count / total energy / energy per contact / energy per residue : 1023 -18072 -17.67 -74.07 target 2D structure prediction score : 0.57 Monomeric hydrophicity matching model chain A : 0.64 3D Compatibility (PKB) : -17.67 2D Compatibility (Sec. Struct. Predict.) : 0.57 1D Compatibility (Hydrophobicity) : 0.64 QMean score : 0.282

(partial model without unconserved sides chains): PDB file : Tito_3CSV.pdb: (Unconserved sides chains are recalculated) : Sequence: align-3csv-query.scw PDB file : Tito_Scwrl_3CSV.pdb: