Modeling by threading (Tito software) Unconserved sides chains calculation (Scwrl software) Evaluation (QMean software) Input alignment information: Query sequence MRSNNNNPLTRDEILSRYFPQ--YRPAVATSQGLSGGSCIIAHD-THRVVLRRHHDPDAPPAHFLRHYRALSQLP-A---SLAPRALFYTPGWMAVEYLHGVVNSA------------------LPDADELAALLYHLHQQPRFGWR-I-----AL---SPLLAQYWSCCDPARRTPFWLRRLKQLQKNG---EPRPLRLAPLHMDVHGDNIVLTS-AGLR-LIDWEYAGDGDIALELAAVWVEDER-QHRQLADAYAARARIDARQLWRQIRLWHPWVIMLKAGWFEYRWRQTGEQQFIRLADETWRQLRMKG 5IWU Chain:A ((2-297)) --SKDIKQVI--EIAKKHNLFLKEETIQFNESGLDFQAVFAQDNNGIDWVLRLPRRED-VMPRTKVEKQALDLVNKYAISFQAPNWIIYTEELIAYKKLDGVPAGTIDHNIGNYIWEIDINNVPELFHKSLGRVLAELHSIPSNKAAALDLVVHTPEEARMSMKQRMDAVRAK--FGVGENLWNRWQAWLNDDDMWPKKTGLIHGDVHAGHTMIDKDANVTGLIDWTEAKVTDVSHDFIFNYRAFGEEGLEALILAYKEIGGYYWPKMKEHIIELNAAYPVSIAEFAL----VSGIEEYEQMAKEAL-------

General information: TITO was launched using: RESULT: Template: 5IWU.pdb Alignment : align.pir Tito was launched with SMD and SCWRL Tito text output Monomeric PKB - chain A - contact count / total energy / energy per contact / energy per residue : 1099 6653 6.05 25.99 target 2D structure prediction score : 0.52 Monomeric hydrophicity matching model chain A : 0.67 3D Compatibility (PKB) : 6.05 2D Compatibility (Sec. Struct. Predict.) : 0.52 1D Compatibility (Hydrophobicity) : 0.67 QMean score : 0.342

(partial model without unconserved sides chains): PDB file : Tito_5IWU.pdb: (Unconserved sides chains are recalculated) : Sequence: align-5iwu-query.scw PDB file : Tito_Scwrl_5IWU.pdb: