Modeling by threading (Tito software) Unconserved sides chains calculation (Scwrl software) Evaluation (QMean software) Input alignment information: Query sequence MGLRKTYAKPYSRGISSPLEALRISPVVLSALKGLLSPDTLSRLTPLGGF------EARVYTD-------GERVY---KVYQPGEAHLAALEAERMARAGLGSFVLG---VAQVEGQGILVIRHFPGKPF-SPESFTPKALAALSHLFLSLHRLPEPGYVE-REELSERLERFA---ESLGSVP---------------EALSLIKALMREVT-----------WVAGVEKRFCHRDAWAGNLLLKTQENPSHDDPEV--------------LLVDWVRSGGDD----PARDLALLKT-------------GSLDLLGE------------KRAREALFRLVQFYPK----EVRERLAFYVPLTYLH--DLH----WFRTKKPEGFLEALAD----------KLPRALSFFQDCFP-LRNRAC 1FP3 Chain:A ((1-402)) MEKERETLQAWKERVGQELDRV--MAFWLEH-----SHD-----REHGGFFTCLGRDGRVYDDLKYVWLQGRQVWMYCRLYRKL-ERFHRPELLDAAKAG-GEFLLRHARVAPPEKKCAFVLTR-DGRPVKVQRSIFSECFYTMAMNELWRV-TAEARYQSEAVDMMDQIVHWVREDPSGLGRPQLPGAVASESMAVPMMLLCLVEQLGEEDEELAGRYAQLGHWCARRILQHVQRDGQA--VLENVSEDGEELSGCLGRHQNPGHALEAGWFLLRHSSRSGDAKLRAHVIDTFLLLPFRSGWDADHGGLFYFQDADGLCPTQLEWAMKLWWPHSEAMIAFLMGYSESGDPALLRLFYQVAEYTFRQFRD-PEYGEWFGYLNREG--KVALTIKGGPFKGCFHVPRCLAMCEEMLSALLSRLA

General information: TITO was launched using: RESULT: Template: 1FP3.pdb Alignment : align.pir Tito was launched with SMD and SCWRL Tito text output Monomeric PKB - chain A - contact count / total energy / energy per contact / energy per residue : 1248 -963 -0.77 -3.34 target 2D structure prediction score : 0.63 Monomeric hydrophicity matching model chain A : 0.65 3D Compatibility (PKB) : -0.77 2D Compatibility (Sec. Struct. Predict.) : 0.63 1D Compatibility (Hydrophobicity) : 0.65 QMean score : 0.216

(partial model without unconserved sides chains): PDB file : Tito_1FP3.pdb: (Unconserved sides chains are recalculated) : Sequence: align-1fp3-query.scw PDB file : Tito_Scwrl_1FP3.pdb: