Modeling by threading (Tito software) Unconserved sides chains calculation (Scwrl software) Evaluation (QMean software) Input alignment information: Query sequence -------------------------------MHRINDFIITDETEIASLLAPFDSTLTILDFSLMKDSMSNSGYIVT--TNSGKYFLKIYSKTTDKIETAALSYLKNKINVPALLFYDGSKQRFPFAY-AIMEFLDGVTFINHVRSNLKYPPEMAYEIGRICAMIHERSYAHDALLDGKLN----------LLQELPRTRDKILHLL-----NGKPSEYLRPETIDSLCGFIKENPDLFDSIEAKSVLCHGDLGYANIMISDGK---VSFIDFEFTYSGSIYHDIGHFFRRK---DDDVEALINRHIYDAFAQGYNSVSASPLPSNWLTLAHLCDISAMLCLLTYDNVPTEWVEDIENDILCAIDEDSRL------ 2QG7 Chain:A ((50-458)) YPITESNLRILEGEDRSEKAKELLKKYVSNVFENEKTLYIYCKYVMLHYGKDLVNPNEVDSLEFQIINGTNILIKVKDMSKQAKYLIRLYGPTDEIINREREKKISCILYNKNI----AKKIYVFFTNGRIEEFMDGYA----LSREDIKNPKFQKLIAKNLKLLHDIKLNENLYKELQVTQKVPGTRPSFLWNTIWKYFHLLNEERKKICSFDAKANILKLIDFDVLRDSIVEVESLCKRENSPIVLCHCDLLSSNIINTVGEGDSISFIDFEYSCPMERAYDIANHFNEYAGFNCDWDLTPSKEEEYHFIMHYLGTDDEELINQLIREIQPFYICSHINWGLWSLLQGMHSFDFINYGMTRLTASCLPIFRSKV

General information: TITO was launched using: RESULT: Template: 2QG7.pdb Alignment : align.pir Tito was launched with SMD and SCWRL Tito text output Monomeric PKB - chain A - contact count / total energy / energy per contact / energy per residue : 1283 -7633 -5.95 -24.86 target 2D structure prediction score : 0.61 Monomeric hydrophicity matching model chain A : 0.63 3D Compatibility (PKB) : -5.95 2D Compatibility (Sec. Struct. Predict.) : 0.61 1D Compatibility (Hydrophobicity) : 0.63 QMean score : 0.305

(partial model without unconserved sides chains): PDB file : Tito_2QG7.pdb: (Unconserved sides chains are recalculated) : Sequence: align-2qg7-query.scw PDB file : Tito_Scwrl_2QG7.pdb: