Modeling by threading (Tito software) Unconserved sides chains calculation (Scwrl software) Evaluation (QMean software) Input alignment information: Query sequence MAVFKNNIALGKSVTEALEILERELGSQYCYCKTLEGCSNEVHIIKDVRSGLPYIM-RFTRQSRFQNYSLEREILSHVVGRGVATSQAYLFA--DGIVAACIEGH-CVESDKMLGDSPYYELIAKQMRRLHEISVQDDGTSVMYSETHYGLKSMLDISVDYIGKGREAELLYKLYSEDGVLGQLVNDHP-SLLWTCISHNDLHSGNIIYSPSAQEVRFIDWEYSTYSINAFDIACFFLEFTGIDCEISAFPCASKRQDFYLYYFGSSSPPIDFLCLFFIPLAC---LFWAAWSSGI--DGL---D--VYTKNRTRLGHATLRKLVNEIWPQCGLTLDKEDCELLELVDFTFQSLYTN 3DXQ Chain:B ((21-286)) -----------------------------GPLERLGGLTNLVFRA------GDLCLRIP-------NRANEAVAAREAAKAGVSPEVLHVDPATGVMVTRYIAGAQTMSPEKFKTRPGSPARAGEAFRKLHGSGAVFPFR----FELFAMIDDYLKVLSTKNVTLP--AGYHDV---VREAGGVRSALAAHPLPLAACHCDPLCENFLDTG--ERMWIVDWEYSGMNDPLWDLGDLSVEGK---------FNANQDEELMRAYFGGEAR--PAERGRVVIYKAMCDLLWTLWGLIQLANDNPVDDFRAYADGRFARCKALME-----------------------------------

General information: TITO was launched using: RESULT: Template: 3DXQ.pdb Alignment : align.pir Tito was launched with SMD and SCWRL Tito text output Monomeric PKB - chain B - contact count / total energy / energy per contact / energy per residue : 1119 -56505 -50.50 -232.53 target 2D structure prediction score : 0.52 Monomeric hydrophicity matching model chain B : 0.62 3D Compatibility (PKB) : -50.50 2D Compatibility (Sec. Struct. Predict.) : 0.52 1D Compatibility (Hydrophobicity) : 0.62 QMean score : 0.219

(partial model without unconserved sides chains): PDB file : Tito_3DXQ.pdb: (Unconserved sides chains are recalculated) : Sequence: align-3dxq-query.scw PDB file : Tito_Scwrl_3DXQ.pdb: