Modeling by threading (Tito software) Unconserved sides chains calculation (Scwrl software) Evaluation (QMean software) Input alignment information: Query sequence MNCVTSLTASDLPVAEVSHSVLHPEFIAAEVARRYPVK-GELTCFLLYR-GMNDVYLVQDEETKYALRVWRKTYR-DVDDV-AYELDFLDYLRQQGFPASVGVPQHDGKLYFKVVSPEGERAIALYDWAPGVKFGDC--LSEETAFKIGAAMARMHLLGDAWAGPDHT-FSTE---TAKDYNICMPALID-FVY---DRPDDLRDYPVIAANLDKRLDELAASGKVPLGVCHRDFHPSNVHVAQ--DGAITLLDFDAAGEDFLMQDVQNFVWGNLFY-----------GFDPKIGEAFEDGYQS--VRPFTKEETENIELFLMAKALRLIAGMAHSSTAVGRGTLRFRNLDWLGDYVKTRARACGLL 4OCV Chain:A ((25-323)) ------------------------NEALFDVASHFALEGTVDSIEPYGDGHINTTYLVTTDGPRYILQRMNTGIFPDTVNLMRNVELVTSTLKAQGKETLDIVRTTSGDTWAEI----DGGAWRVYKFIEHTMS-YNLVPNPDVFREAGRAFGDFQNFLSGFDANQLTETIAHFHDTPHRFEDFKKALAADELGRAAGCGPEIEFYLSHADQYAVVMDG-LRDGSIPLRVTHNDTKLNNILMDATTGKARAIIDLDTIMPGSMLFDFGDSIRFGASTALEDERDLDKVHFSTELFRAYTEGFVGELRDSITAREAELLPFSGNLLTMEC--------------------------------------

General information: TITO was launched using: RESULT: Template: 4OCV.pdb Alignment : align.pir Tito was launched with SMD and SCWRL Tito text output Monomeric PKB - chain A - contact count / total energy / energy per contact / energy per residue : 1143 -15845 -13.86 -58.68 target 2D structure prediction score : 0.60 Monomeric hydrophicity matching model chain A : 0.64 3D Compatibility (PKB) : -13.86 2D Compatibility (Sec. Struct. Predict.) : 0.60 1D Compatibility (Hydrophobicity) : 0.64 QMean score : 0.319

(partial model without unconserved sides chains): PDB file : Tito_4OCV.pdb: (Unconserved sides chains are recalculated) : Sequence: align-4ocv-query.scw PDB file : Tito_Scwrl_4OCV.pdb: