Modeling by threading (Tito software) Unconserved sides chains calculation (Scwrl software) Evaluation (QMean software) Input alignment information: Query sequence MIIEINGKWIFRFPRNPISKENTKERLDFLISFSKVSSLKIPVPKYV---------ENNFIGYEKIQGSHPRPTNIKNLAELDKLKIAKQLGLFLKDLH--NFKSKKINFDTGYLIMRKGDYKTCPKEITKYLNADEIKNLETKLKAIANNPLNFKKPTSIIHGDFYFNNIIWNPDKKVITGVIDWANLGLGTPAMDFIMLADFNKNTNDKFLKDILKYYGAKGDDLFFQIKENAIIDAMNWFWSYYKEKNPKGVARMIKKLKKLLAE 6CD7 Chain:A ((39-256)) ---EINRDFIFKFPKHSRGSTNLFNEVNILKRIH--NKLPLPIPEVVFTGMPSETYQMSFAGFTKIKGVPLTPLLLNNLPKQSQNQAAKDLARFLSELHSINISGFKSNLVLDFREKINEDNKKIKKLLSRELKGPQMKKVDDFYRDILENEIYFKYYPCLIHNDFSSDHILFDTEKNTICGIIDFGDAAISDPDNDFISLMEDDEEYGMEFVSKILNHYKHK---------------------------------------------

General information: TITO was launched using: RESULT: Template: 6CD7.pdb Alignment : align.pir Tito was launched with SMD and SCWRL Tito text output Monomeric PKB - chain A - contact count / total energy / energy per contact / energy per residue : 801 40521 50.59 195.75 target 2D structure prediction score : 0.58 Monomeric hydrophicity matching model chain A : 0.70 3D Compatibility (PKB) : 50.59 2D Compatibility (Sec. Struct. Predict.) : 0.58 1D Compatibility (Hydrophobicity) : 0.70 QMean score : 0.463

(partial model without unconserved sides chains): PDB file : Tito_6CD7.pdb: (Unconserved sides chains are recalculated) : Sequence: align-6cd7-query.scw PDB file : Tito_Scwrl_6CD7.pdb: