Modeling by threading (Tito software) Unconserved sides chains calculation (Scwrl software) Evaluation (QMean software) Input alignment information: Query sequence MDDLDKPIAYGRTAEIFAWGENQVLKLFHAWVGFDAVEYEYRIARTMQSCGLP-VPQVGEIIEY-----KGRYGITCQRIKGISMTESLA--------------------RAPWKILRYARRMAELHARVHAVTHPTDIPPLNPKMARKILQA----QSLPARLREKALTRLEK---LPEGHDLCHGDFHPDNILLTPQGEVILDWMDAGT-------GNPLADLARTSIILKG-SIESGQ--------IR---HPLLKRLAHLFHRAYLAQYFSLRPGGESEYALWLPIIAAARLSENISELEGWLVAQAERGLS 5JY7 Chain:L ((124-400)) ----PRVFGAEQSNTSVVFGEDAIFKLFRRI--TPGVHPDIELNRVLARAGNPHVARLLGSFETEWEGEPYALGMVTEFAANSAEGWDMATTSTRDLFAEGDLYAEEVGGDFAGEAYRLGEAVASVHACLAHELGTEEVPFPADVMAQRLAAAVDAVPEL-REHVPQIEERYHKLADTTMTVQRVHGDLHLGQVLRTPKGWLLIDFEGEP-LDERRRPDTPVRDVAGILRSFEYAAHQRLVDQAGDDDDRARQLAARAREWVTRNCASFCDGYAAEAGTDPR----------------------------------

General information: TITO was launched using: RESULT: Template: 5JY7.pdb Alignment : align.pir Tito was launched with SMD and SCWRL Tito text output Monomeric PKB - chain L - contact count / total energy / energy per contact / energy per residue : 839 3615 4.31 16.28 target 2D structure prediction score : 0.69 Monomeric hydrophicity matching model chain L : 0.66 3D Compatibility (PKB) : 4.31 2D Compatibility (Sec. Struct. Predict.) : 0.69 1D Compatibility (Hydrophobicity) : 0.66 QMean score : 0.284

(partial model without unconserved sides chains): PDB file : Tito_5JY7.pdb: (Unconserved sides chains are recalculated) : Sequence: align-5jy7-query.scw PDB file : Tito_Scwrl_5JY7.pdb: