Modeling by threading (Tito software) Unconserved sides chains calculation (Scwrl software) Evaluation (QMean software) Input alignment information: Query sequence MIEISLNKINKSYGFNPILKDFSFEIKSGERIALIGPNGCGKTTTLRIIMGE-DIDSGSINIR--K-G-------ARVGYLSQIPNKEKDNVKAKEVFYRGVKELIELENNINEFVKNMNSSEKSIKALDRLQEEFRIKGGYQLNERINKIKNGFKLSDELLDTEYNNLSGGEKTIINLASLVLSEVDVLLLDEPTNHLDIETLEWFEEYLNNYKGACLIVSHDRYFLDRVINKIVEIKNCKEEVYYGNYSYYLKESEKRFLLQFQSYKNQQKEITAIKEAIVRLKEWGTKSDNPMFFRRAAAMQKRLDRMELIDKPVEKS--ELKVNFVTTDRSGNEVLKIKNLDLNIGS-RELLVSSNMEIYYQDRVCLMGRNGTGKTTLIKNIIN---NTHDNIILGTNIKIGYIPQEIRF-DNEELTIYEHMRKIFVGSESELRSKLNRFYFGSEEIDKKLKNISGGEKVRIKLLELILLKSNFLILDEPTNHIDIDTREILEEALLDFDGTILFISHDRYFINKIATRIVRIENKKLVSYEGNYDSLKVKTVPVIENTIKETPQVINIKGSNRLNEFIKDAKIEEVTIGCSNTKVYKIRKKSKVFFLKVADHLSQESIRLDYLQDKILVPEKVFYEKYNGKSYILTKSLKGEMLCSDYYSNHPLEGINIIVEAFNNLYNIDYSDCVIDETIDTKIKRIEDRFSKINNEDINKKILNRFITKENILKYLKGNKPKQIIGFTHGDMSLPNIFACDGHFSGLLDVSECGLGDIYFDLVICEISIERNYGKEYIDKFYESLGIEKDEFKSEYYRILMSL 5ZXD Chain:B ((3-529)) -SDIKLEKFSISAHGKELFVNADLYIVAGRRYGLVGPNGKGKTTLLKHIANRALSIPPNIDVLLCEQEVVADETPAVQAVLRADTKRL-KLLEEERRLQGQLEQG---DD----------TAAER---LEKVYEELRATGAAAAEAKARRILAGLGFDPEMQNRPTQKFSGGWRMRVSLARALFMEPTLLMLDEPTNHLDLNAVIWLNNYLQGWRKTLLIVSHDQGFLDDVCTDIIHLDAQRLHYYRGNYMTFKKMYQQKQKELLKQ----------------------------------------------------PKEYTVRFTFPDPPPLSPPVLGLHGVTFGYQGQKPLFKNLDFGIDMDSRICIVGPNGVGKSTLLLLLTGKLTPTHGEMRKNHRLKIGFFNQQYAEQLRMEETPTEYLQRGFNLPYQDARKCLGRFGLESHAHTIQICKLSGGQKARVVFAELACREPDVLILDEPTNNLDIESIDALGEAINEYKGAVIVVSHDARLITETNCQLWVVEEQSVSQIDGDFEDYK---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------

General information: TITO was launched using: RESULT: Template: 5ZXD.pdb Alignment : align.pir Tito was launched with SMD and SCWRL Tito text output Monomeric PKB - chain B - contact count / total energy / energy per contact / energy per residue : 2276 46601 20.47 102.42 target 2D structure prediction score : 0.65 Monomeric hydrophicity matching model chain B : 0.66 3D Compatibility (PKB) : 20.47 2D Compatibility (Sec. Struct. Predict.) : 0.65 1D Compatibility (Hydrophobicity) : 0.66 QMean score : 0.265

(partial model without unconserved sides chains): PDB file : Tito_5ZXD.pdb: (Unconserved sides chains are recalculated) : Sequence: align-5zxd-query.scw PDB file : Tito_Scwrl_5ZXD.pdb: