Modeling by threading (Tito software) Unconserved sides chains calculation (Scwrl software) Evaluation (QMean software) Input alignment information: Query sequence MKDTILDALKAAYKLDADNLIANRFGSGHIHKTYKVESSTQSFILQEFNDTVFKYPERISNNLGYLLDNFDPANIPFVLPLPIPNIDGGLFTELDGGLYRLFPFVNGVTRDDI----DYKEQASKAAEAFAHFVLVFLPTDSNKLQDTIQDFHHLGWRYSQFDAALKAPAIEIDEETREMIAYYETRKDLLEQY-----GIYRNKLPLRATHNDTKINNLIFSEDLKKVNAVIDLDTIMAGFVFYDFGDLARTVACTRDESSLDWGKIKIDMVKYEGLLEGFYTVLAGHVTEEELNSLSFGAEMMTLIMGLRFLTDHLQGNTYYQVDYVEQNLHRSKNQAELLTAFMEKREEIKTLETNLKRKFL 4OCU Chain:A ((47-370)) ------------------------YGDGHINTTYLVTTDGPRYILQRMNTGIFPDTVNLMRNVELVTSTL-KAQGKETLDI-VRTTSGDTWAEIDGGAWRVYKFIEHTMSYNLVPNPDVFREAGRAFGDFQNFLSGF---DANQLTETIAHFHDTPHRFEDFKKALAADELGRAAGCGPEIEFYLSHAD---QYAVVMDGLRDGSIPLRVTHNDTKLNNILMDATTGKARAIIDLDTIMPGSMLFDFGDSIRFGASTALEDERDLDKVHFSTELFRAYTEGFVGELRDSITAREAELLPFSGNLLTMECGMRFLADYLEGDVYFATKYPEHNLVRSRTQIKLVREMEQRADETRAI---------

General information: TITO was launched using: RESULT: Template: 4OCU.pdb Alignment : align.pir Tito was launched with SMD and SCWRL Tito text output Monomeric PKB - chain A - contact count / total energy / energy per contact / energy per residue : 1621 -23336 -14.40 -74.08 target 2D structure prediction score : 0.56 Monomeric hydrophicity matching model chain A : 0.75 3D Compatibility (PKB) : -14.40 2D Compatibility (Sec. Struct. Predict.) : 0.56 1D Compatibility (Hydrophobicity) : 0.75 QMean score : 0.337

(partial model without unconserved sides chains): PDB file : Tito_4OCU.pdb: (Unconserved sides chains are recalculated) : Sequence: align-4ocu-query.scw PDB file : Tito_Scwrl_4OCU.pdb: