Modeling by threading (Tito software) Unconserved sides chains calculation (Scwrl software) Evaluation (QMean software) Input alignment information: Query sequence --------------------MISLESLEENFRFLTLEVANQAR--------ATRDILGKPE-----KELVERLIAR---------DDYIDNLKTIIENKCFSRIHAEEGAEQSESNRIRAIHIICVNLERIADHCVNIVRQIKH-------FSDPTFLHRYEFHSMFNLIQSGLDMILPVQRSQKVAQALTICKIEHELDNQYKERFDQIQDEMRAQHNADVGDLI-------------TALFIFRYLERIGDALLNVGEAFIFAFLGEKIKIHQFQALQETLSQAGYEGSLSEIDFESIWGGRSGCRIRRVKNTNPDPSKEVIFKEGQKEKIQQERDNIDR-WSDLFPGIAPHVVGYNEGGNYASMLVEFLPGCTLDEVVLTTEPEQVRNALFV--FEQTLV--DVWEDTIDPQDHPS-PGFIKQLSGRLDKIQQVHPGILTPHKRIGRITIPSLRKRLEQGTALEQAVQAPFTVLLHGDCNLNNVVYDFEEQRIRFIDLYRSRQADYIQDVSVFLVSNFRMPIFEPSLRARLNWTIRHFYHFARGFAAKHGDTTFSFRLALGLCRSFLTSTRFELDTEFAYEMAERGGYLLDRLLEHGSKHQEEFTFPEAV-LYY 4XGC Chain:C ((1-676)) MQPFYEEYRKAWNQINDHIADLQHRSYARTLEQLVDFVVGQAERDEVLPTAALLTGINQPDHLSQFTALTQRLHAQRAAMVCVLQSRDCATLKAAVETLVFGLVEDNAEVEQLRRSQ--------CTMKQLKSWYTNNFDSEQKRRQLVVILPDFECFNASVLQDLILILSAHCGS-LPFVLVLGVATAMTAVHGTLPYHVSSKIRLRVFQTQAAPTGLNEVLDKVLLSPKYAFHLSGKTFKFLTHIFLYYDFSIHGFIQGFKYCLMEHFFGGNAFALCTDYSKALGRIKQLTHEDMETIRRLPS-----------FRPYVEQINDCKRIIAVLTDDDYLKKKLPQLLRDCLLHFLLFRCSLEFLTELVGDLPRCPLG---------KLRRELYVNCLNRAIISTPEYKECLQMLSFLSKDEFVAKVNRALERTEQFLVEEIAPLE-LGEACTAVLRPKLE---AIRLAVD-------EVGRALQKTLQLIETQ-IVQDHLRALQDAPPIHEL--FVFSD------IATVRRNIIGAPRAALHTALN-NPHFPDLSVVYKLHLECGRMINLFDWLQAFRSVVPQIQARFTRAVAELQFLGYIKMSKRKTDHATRLTW

General information: TITO was launched using: RESULT: Template: 4XGC.pdb Alignment : align.pir Tito was launched with SMD and SCWRL Tito text output Monomeric PKB - chain C - contact count / total energy / energy per contact / energy per residue : 2190 30372 13.87 60.99 target 2D structure prediction score : 0.54 Monomeric hydrophicity matching model chain C : 0.65 3D Compatibility (PKB) : 13.87 2D Compatibility (Sec. Struct. Predict.) : 0.54 1D Compatibility (Hydrophobicity) : 0.65 QMean score : 0.238

(partial model without unconserved sides chains): PDB file : Tito_4XGC.pdb: (Unconserved sides chains are recalculated) : Sequence: align-4xgc-query.scw PDB file : Tito_Scwrl_4XGC.pdb: