Modeling by threading (Tito software) Unconserved sides chains calculation (Scwrl software) Evaluation (QMean software) Input alignment information: Query sequence MISLESLEENFRFLTLEVANQARATRDILGKPEKELVERLIARDDYI-DNLKTIIENKCFSRIHAEEGAEQSESNRIRAIHIICVNLERIADHCVNIVRQIKHFSDPTFLH--RYEFHSMFNLIQSGLDMILPVQRSQKVAQALTICKIEHELDNQYKERFDQIQDEMRAQHNADVGDLITALFIFRYLERIGDALLNVGEAFIFAFLGEKIK-IHQFQALQETLSQAGYE-GSLSEIDFESIWGGRSGCRI------RRVKNTNPDPSKEVIFKEGQKEKIQQER---------DNIDRWSDLFPGI----APHVVGYNEGGNYASMLVE-FLPGCTLDEVVLTTEPEQVRNALFVFEQTLVDVWEDTIDP-----------------QDHPSPGFIKQLSGRLDKIQQVHPGILTPHKRIGRITIPSLRKRLEQGTALEQAVQAPFTVLLHGDCNLNNVVYDFEEQRIRFIDLYRSRQ------------ADYIQDVSVFLVSNFRMPIFEPSLRARLNWTIRHFYHFARGFAAKHGDTTFSFRLALGLCRSF--------------LTSTRFELDTEFAYEMAERGGYLLDRLLEHGSKHQEEFTF------P-EAVLYY 1CIY Chain:? ((33-609)) ---------------YTPIDISLSLTQFLLSEFVPGAGFVLGLVDIIWGIFGPSQWDAFLVQIEQLINQRIE----EFARNQAISRLEGLSNLYQIYAESFREWEADPTNPALREEMRIQFNDMNSALTTAIPLLAVQNYQVPL--LSVYVQAANLHLSVLRDVSVFGQRWGFDAATINSRYNDLTRLIGNYTDYAVRWYNTGLERVWGPDSRDWVRYNQFRRELTLTVLDIVALFSNYDSRRYPIRTVSQLTREIYTNPVLENFDGSFR------GMAQRIEQNIRQPHLMDILNSITIYTDVHRGFNYWSGHQITASPVGFSGPEFAFPLFGNAGNAAPPVLVSLTG--LGIFRTLSSPLYRRIILGSGPNNQELFVLDGTEFSFASLTTNLPSTIYRQRGTVDSLDVIPPQDNSVPPRAGFSHRLSHVTMLSQAAGAVYTLRAPTFSWQHRSAEFNNIIPSSQITQIPLTKSTNLGSGTSVVKGPGFTGGDILRRTSPGQISTLRVNITAPLSQ---RYRVRIRY-------ASTTNLQFHTSID-G--RPINQGNFSATMSSGSNLQSGSFRT-VGFTTPFNFSNGSSVFTLSAHVFNSGNEVYIDRIEFVPAEVT---

General information: TITO was launched using: RESULT: Template: 1CIY.pdb Alignment : align.pir Tito was launched with SMD and SCWRL Tito text output Monomeric PKB - chain A - contact count / total energy / energy per contact / energy per residue : 2586 27329 10.57 54.44 target 2D structure prediction score : 0.50 Monomeric hydrophicity matching model chain A : 0.62 3D Compatibility (PKB) : 10.57 2D Compatibility (Sec. Struct. Predict.) : 0.50 1D Compatibility (Hydrophobicity) : 0.62 QMean score : 0.183

(partial model without unconserved sides chains): PDB file : Tito_1CIY.pdb: (Unconserved sides chains are recalculated) : Sequence: align-1ciy-query.scw PDB file : Tito_Scwrl_1CIY.pdb: