Modeling by threading (Tito software) Unconserved sides chains calculation (Scwrl software) Evaluation (QMean software) Input alignment information: Query sequence MKSRTGDPTDAEVREIGILAGNQRATCDDRAYFQAAAERLAMLPDASEPDVPVLLLEQHYGQQGALTALSSEVERTFDARLADGRAFILKTSSRPQALESFQFQSAALAGLRGAD-GVMAPKVIDTLSGGLMFEHEGGCGYLQTRMDGIPLHMVPRTPEILREVG-AALARLNLAMKDTDPPAARR--------PVLWNIACWP-WLVEL-ERYLSKGRTAKLVRSAMAEYIRDISPHIADLD--------------WQVTHNDPSPFNMI-DTGKGIGFIDFGDGGWNPRVQDLAI-AAGHFVIDPRTPLGGAEHV-IAGYASLAPLSELEASL-L------LGLMRARQSALVLINNWRSHLFPAAAPYIMKNVKRAEQGLAVLALLDVSSGEAAIRAAAGLDPP 2Q83 Chain:A ((11-346)) LSAEDAKKLTELAENVLQGWDVQ------------------------------------------AEKIDVIQALVWKVHTDSGAVCLKRI---HRPEKKALFSIFAQDYLAKKGMNV--PGILPNKKGSLYSKHGSFLFVVYDWIEGRPF---ELTVKQDLEFIMKGLADFHTASVGYQPPNGVPIFTKLGRWPNHYTKRCKQMETWKLMAEAEKEDPFSQLYLQEIDGFIEDGLRIKDRLLQSTYVPWTEQLKKSPNLCHQDYGTGNTLLGENEQIWVIDLDTVSFDLPIRDLRKMIIPLLDTTGVWD-DETFNVMLNAYESRAPLTEEQKQVMFIDMLFPYELYDVIREKYVRKSALPKEELESAFEYERIKANALRQLI------------------------

General information: TITO was launched using: RESULT: Template: 2Q83.pdb Alignment : align.pir Tito was launched with SMD and SCWRL Tito text output Monomeric PKB - chain A - contact count / total energy / energy per contact / energy per residue : 1237 -3803 -3.07 -12.85 target 2D structure prediction score : 0.47 Monomeric hydrophicity matching model chain A : 0.59 3D Compatibility (PKB) : -3.07 2D Compatibility (Sec. Struct. Predict.) : 0.47 1D Compatibility (Hydrophobicity) : 0.59 QMean score : 0.258

(partial model without unconserved sides chains): PDB file : Tito_2Q83.pdb: (Unconserved sides chains are recalculated) : Sequence: align-2q83-query.scw PDB file : Tito_Scwrl_2Q83.pdb: