Modeling by threading (Tito software) Unconserved sides chains calculation (Scwrl software) Evaluation (QMean software) Input alignment information: Query sequence MTLTDVLDDWPLWGISKQPISANQISILEGGLTNRCYQLSLESGEYIIRISAANTAELGIDRNVEKTIHQLVSSLNFTSAIRYCDDENRYLIRDYIEGE-VLSDNVED-MSHNTLSYMVEQLKALHQVPVEIDLPVVNISEKAEAYWQMLATQQP--NNEILKMKP----LMQVAMSEPPAGDFCLCHLDPVLANWLYTAEGLQLLDWEYAGLAHPLWDLAALFQGIKHSFQQLEKKSKKNSHSEIEQNLENKILTLYGVSDLVAWRRACMQMEYLSSLWYQAQAKKDSY 3DXQ Chain:B ((6-262)) --ARAKLAAIPMLAG------YTGPLERLGGLTNLVFRA----GDLCLRIP---------NRANEAVAAREAAKAGVSPEVLHVDPATGVMVTRYIAGAQTMSPEKFKTRPGSPA-RAGEAFRKLHGSGAVFPFR-FELFAMIDDYLKVLSTKNVTLPAGYHDVVREAGGVRSA-LA-AHPLPLAACHCDPLCENFLDTGERMWIVDWEYSGMNDPLWDLGDLSVEGKFNANQDEELMR-----AYFGGEA-------RPAERGRVVIYKAMCDLLWTLWGLIQLA----

General information: TITO was launched using: RESULT: Template: 3DXQ.pdb Alignment : align.pir Tito was launched with SMD and SCWRL Tito text output Monomeric PKB - chain B - contact count / total energy / energy per contact / energy per residue : 1137 -45438 -39.96 -188.54 target 2D structure prediction score : 0.68 Monomeric hydrophicity matching model chain B : 0.66 3D Compatibility (PKB) : -39.96 2D Compatibility (Sec. Struct. Predict.) : 0.68 1D Compatibility (Hydrophobicity) : 0.66 QMean score : 0.330

(partial model without unconserved sides chains): PDB file : Tito_3DXQ.pdb: (Unconserved sides chains are recalculated) : Sequence: align-3dxq-query.scw PDB file : Tito_Scwrl_3DXQ.pdb: