Modeling by threading (Tito software) Unconserved sides chains calculation (Scwrl software) Evaluation (QMean software) Input alignment information: Query sequence -CVIGLTFNGNWVPNNRFVISPGGKFSFIANYVIIPVRLDESCHWHQDLAENAKPVIIPSGYGIKSC---------- 2JVE Chain:A ((18-88)) MALKCFTRNGD---DRTVTTCAEEQTRCL--FVQLPYSEIQECKTVQQCAEVLEEVT-AIGYPAKCCCEDLCNRSEQ

General information: TITO was launched using: RESULT: Template: 2JVE.pdb Alignment : align.pir Tito was launched with SMD and SCWRL Tito text output Monomeric PKB - chain A - contact count / total energy / energy per contact / energy per residue : 217 -13915 -64.12 -231.91 target 2D structure prediction score : 0.57 Monomeric hydrophicity matching model chain A : 0.70 3D Compatibility (PKB) : -64.12 2D Compatibility (Sec. Struct. Predict.) : 0.57 1D Compatibility (Hydrophobicity) : 0.70 QMean score : 0.297

(partial model without unconserved sides chains): PDB file : Tito_2JVE.pdb: (Unconserved sides chains are recalculated) : Sequence: align-2jve-query.scw PDB file : Tito_Scwrl_2JVE.pdb: