Modeling by threading (Tito software) Unconserved sides chains calculation (Scwrl software) Evaluation (QMean software) Input alignment information: Query sequence RMCILALAEKNQNPEKPSFLED----TFQEIEAPAAAMLSYGGHEIHF--------------ELDKNCWPRLRHGSAVPSGY-SAHVY 3NVT Chain:A ((250-321)) ---------------KPILLKRGLSATIEEFIGAAEYIMSQGNGKIILCERGIRTYEKATRNTLDISAVPILKKETHLPVMVDVTHS-

General information: TITO was launched using: RESULT: Template: 3NVT.pdb Alignment : align.pir Tito was launched with SMD and SCWRL Tito text output Monomeric PKB - chain A - contact count / total energy / energy per contact / energy per residue : 137 -2492 -18.19 -47.02 target 2D structure prediction score : 0.51 Monomeric hydrophicity matching model chain A : 0.71 3D Compatibility (PKB) : -18.19 2D Compatibility (Sec. Struct. Predict.) : 0.51 1D Compatibility (Hydrophobicity) : 0.71 QMean score : 0.291

(partial model without unconserved sides chains): PDB file : Tito_3NVT.pdb: (Unconserved sides chains are recalculated) : Sequence: align-3nvt-query.scw PDB file : Tito_Scwrl_3NVT.pdb: