Modeling by threading (Tito software) Unconserved sides chains calculation (Scwrl software) Evaluation (QMean software) Input alignment information: Query sequence --------------------------------------------------------------------------------------------------------------------------------------------------------------YECYVSLTINGIEHYKPEGRMEFPGATTVYDIGG-YGTVVIVLGDTCEPIYKTELKLPQAFDFSSRIFKKR--------------------------------------------------------------------------------------------------------------------------- 1X19 Chain:A ((10-359)) HSSGLVPRGSHMMSNNDLLNYYHRANELVFKGLIEFSCMKAAIELDLFSHMAEGPKDLATLAADTGSVPPRLEMLLETLRQMRVINLEDGKWSLTEFADYMFSPTPKEPNLHQTPVAKAMAFLADDFYMGLSQAVRGQKNFKGQVPYPPVTREDNLYFEEIHRSNAKFAIQLLLEE--AKLDGVKKMIDVGGGIGDISAAMLKHFPELDSTILNLPGAIDLVNENAAEKGVADRMRGIAVDIYKESYPEADAVLFCRILYSANEQLSTIMCKKAFDAMRSGGRLLILDMVIDDPENPNFDYLSHYILGAGMPFSVLGFKEQARYKEILESLGYKDVTMVRKYDHLLVQAVKP

General information: TITO was launched using: RESULT: Template: 1X19.pdb Alignment : align.pir Tito was launched with SMD and SCWRL Tito text output Monomeric PKB - chain A - contact count / total energy / energy per contact / energy per residue : 100 7780 77.80 114.40 target 2D structure prediction score : 0.43 Monomeric hydrophicity matching model chain A : 0.52 3D Compatibility (PKB) : 77.80 2D Compatibility (Sec. Struct. Predict.) : 0.43 1D Compatibility (Hydrophobicity) : 0.52 QMean score : 0.335

(partial model without unconserved sides chains): PDB file : Tito_1X19.pdb: (Unconserved sides chains are recalculated) : Sequence: align-1x19-query.scw PDB file : Tito_Scwrl_1X19.pdb: