@TOME V2.3
(Mar 2018)

Ref. - - Doc.
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Alignment:

3D Common Core:

Structural Clustering:

Modeller Result :

Complexes Modeling
Templates Information:
Sequence & Result Tab:

Values color: [ Good | Correct | Middling | Bad ]Sequence color : MutatedHelixStrandConserved

Query sequence : LINJ_14_1140: (2018-07-13 )
MLEATNAARRRTSSIEQRNSYEALMHAIENRVNGDTVNITSIESKDAAASTGGYAAAPATATAAPKHVDPMATNGISQSEMLSAHLTEQLTDIPAALSPGSCVRQQSQQLPPAQRKKYGKEEVPTVAAAETDAAVRNTQQPAVPSQQQQQQCQRADMKHHADVADVGSEDDDDDGGAAQGDNEQALSLAALHSQPPITRRHAPTAMLEADEDEDDDDGTAYDGVKTQVLFKPVNRAAYREVVASTWKPEGLTRRTNTAGSGSQQNRNSNSSSSASEYKDSPHHPNSSDDDEEAIATMATRNKTGRAAARTAPSMKVFRVPSFPYGGGVTEQQARILQRQFDECIHNGEHLSSNAAGPALITKRDFDSGNYTEVSAATAQMDTTSFQPTSPYEFVVEVERDVRFDAVKAREERRHRFRQLVREKRAPATMGTFNLRVIMDPFKTGFEEEKNFPIVPGTVIAGRYEIIQMLGKATFSRAVRCYDLQDPIYNEDEESDEGEYEDDVDDDDANSATASPADGTENVACIGKGGVTTASCRGSDTATTASASKQQVKSVNTATKSRLKPKRRILGYGQVCLKIINNTKDFFDQSLDEIRLLTLLNRQKDPDDAHIVRLIDAFYYKEHVMLVTELLRDTLYDYGKYNREEEKEFYFTLPRLRRLTRQIVEALTYVHSLNLIHTDLKPENIMFVSYSRCIVKVIDFGSSCFLSDHLSSYIQSRSYRAPEVVLGCDYDGRIDVWSLGAILVEMVTGDVLFTSDTVPEMLARIVYVCGTPFPRRMLWEGRHTSDYINKFGCIYEYGGGADGQHDRPEKGDTDDGEEPYCLYTPVPTMAPHTCASSRKSRAAAAVPPPPRTTTAPYSVLREKLAAANMVDEEFIAFVEACLMLDHKKRPTSAELLEHPFIRDVVL

Atome Classification :

(20 SA) .........10........20........30........40........50........60........70........80........90........100.......110.......120.......130.......140.......150.......160.......170.......180.......190.......200.......210.......220.......230.......240.......250.......260.......270.......280.......290.......300.......310.......320.......330.......340.......350.......360.......370.......380.......390.......400.......410.......420.......430.......440.......450.......460.......470.......480.......490.......500.......510.......520.......530.......540.......550.......560.......570.......580.---......590.......600.......610.......------620.......630.......640.......650.......660.......--670.--........680.......-----------------------690---------------.........700......-------.710.......720....-...730.......740.......750.......760.......770.......780.......790.......800.......810.......820.......830..--.....840.......850.......860.......870.......880.......890.......900...
(Atome) (Ident) (Tito) (Num) (QMean) (Ligand) (Uniprot) MLEATNAARRRTSSIEQRNSYEALMHAIENRVNGDTVNITSIESKDAAASTGGYAAAPATATAAPKHVDPMATNGISQSEMLSAHLTEQLTDIPAALSPGSCVRQQSQQLPPAQRKKYGKEEVPTVAAAETDAAVRNTQQPAVPSQQQQQQCQRADMKHHADVADVGSEDDDDDGGAAQGDNEQALSLAALHSQPPITRRHAPTAMLEADEDEDDDDGTAYDGVKTQVLFKPVNRAAYREVVASTWKPEGLTRRTNTAGSGSQQNRNSNSSSSASEYKDSPHHPNSSDDDEEAIATMATRNKTGRAAARTAPSMKVFRVPSFPYGGGVTEQQARILQRQFDECIHNGEHLSSNAAGPALITKRDFDSGNYTEVSAATAQMDTTSFQPTSPYEFVVEVERDVRFDAVKAREERRHRFRQLVREKRAPATMGTFNLRVIMDPFKTGFEEEKNFPIVPGTVIAGRYEIIQMLGKATFSRAVRCYDLQDPIYNEDEESDEGEYEDDVDDDDANSATASPADGTENVACIGKGGVTTASCRGSDTATTASASKQQVKSVNTATKSRLKPKRRILGYGQVCLKIINNTK---DFFDQSLDEIRLLTLLNRQKDPDDAHIVRLIDAFYY------KEHVMLVTELLRDTLYDYGKYNREEEKEFYFTLPRLRRLTRQIVEALTYV--H--S--LNLIHTDLKPENIMFVSY-----------------------S-----------------RCIVKVIDFGSSCFLSDH-------LSSYIQSRSYRAPEVVLG-CDYDGRIDVWSLGAILVEMVTGDVLFTSDTVPEMLARIVYVCGTPFPRRMLWEGRHTSDYINKFGCIYEYGGGADGQHDRPEKGDTDDGEEPYCLYTPVPTMAPHTCA--SSRKSRAAAAVPPPPRTTTAPYSVLREKLAAANMVDEEFIAFVEACLMLDHKKRPTSAELLEHPFIRDVVL
3 PsiBlast_PDB 88.2030% -93 - C1 - - 3KVW DYRK2_HUMAN A:[124-413] --------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------HVALKMVRNEK---RFHRQAAEEIRILEHLRKQDKDNTMNVIHMLENFTF------RNHICMTFELLSMNLYELIKKNKFQG----FSLPLVRKFAHSILQCLDAL--H--K--NRIIHCDLKPENILLKQQ-----------------------G-----------------RSGIKVIDFGSSCYEHQR-------VYTYIQSRFYRAPEVILG-ARYGMPIDMWSLGCILAELLTGYPLLPGEDEGDQLACMIELLGMP-SQKLLDASKRAKNFVSSKG---------------------------YPRYCTVTTLSD--VVLNGGRSRRGKLRGPPESREWGN---------ALKGCDDPLFLDFLKQCLEWDPAVRMTPGQALRHPWLR----
4 PsiBlast_PDB 87.6530% -95 - C1 - - 4AZF DYRK2_HUMAN A:[124-413] --------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------HVALKMVRNEK---RFHRQAAEEIRILEHLRKQDKDNTMNVIHMLENFTF------RNHICMTFELLSMNLYELIKKNKFQG----FSLPLVRKFAHSILQCLDAL--H--K--NRIIHCDLKPENILLKQQ-----------------------G-----------------RSGIKVIDFGSSCYEHQR-------VYTYIQSRFYRAPEVILG-ARYGMPIDMWSLGCILAELLTGYPLLPGEDEGDQLACMIELLGMP-SQKLLDASKRAKNFVSSKG---------------------------YPRYCTVTTLSD--VVLNGGRSRRGKLRGPPESREWGN---------ALKGCDDPLFLDFLKQCLEWDPAVRMTPGQALRHPWLR----
5 PsiBlast_PDB 86.5930% -91 - C1 - - 3K2L - DYRK2_HUMAN A:[124-413] --------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------HVALKMVRNEK---RFHRQAAEEIRILEHLRKQDKDNTMNVIHMLENFTF------RNHICMTFELLSMNLYELIKKNKFQG----FSLPLVRKFAHSILQCLDAL--H--K--NRIIHCDLKPENILLKQQ-----------------------G-----------------RSGIKVIDFGSSCYEHQR-------VYTYIQSRFYRAPEVILG-ARYGMPIDMWSLGCILAELLTGYPLLPGEDEGDQLACMIELLGMP-SQKLLDASKRAKNFVSSKG---------------------------YPRYCTVTTLSDGSVVLNGGRSRRGKLRGPPESREWGN---------ALKGCDDPLFLDFLKQCLEWDPAVRMTPGQALRHPWLR----
2 PsiBlast_PDB 85.8630% -88 - C1 - - 5LXD DYRK2_HUMAN A:[103-392] --------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------HVALKMVRNEK---RFHRQAAEEIRILEHLRKQDKDNTMNVIHMLENFTF------RNHICMTFELLSMNLYELIKKNKFQG----FSLPLVRKFAHSILQCLDAL--H--K--NRIIHCDLKPENILLKQQ-----------------------G-----------------RSGIKVIDFGSSCYEHQR-------VYTYIQSRFYRAPEVILG-ARYGMPIDMWSLGCILAELLTGYPLLPGEDEGDQLACMIELLGMP-SQKLLDASKRAKNFVSSKG---------------------------YPRYCTVTTLSDGSVVLNGGRSRRGKLRGPPESREWGN---------ALKGCDDPLFLDFLKQCLEWDPAVRMTPGQALRHPWLR----
1 PsiBlast_PDB 84.0730% -87 - C1 - - 5LXC DYRK2_HUMAN A:[103-392] --------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------HVALKMVRNEK---RFHRQAAEEIRILEHLRKQDKDNTMNVIHMLENFTF------RNHICMTFELLSMNLYELIKKNKFQG----FSLPLVRKFAHSILQCLDAL--H--K--NRIIHCDLKPENILLKQQ-----------------------G-----------------RSGIKVIDFGSSCYEHQR-------VYTYIQSRFYRAPEVILG-ARYGMPIDMWSLGCILAELLTGYPLLPGEDEGDQLACMIELLGMP-SQKLLDASKRAKNFVSSKG---------------------------YPRYCTVTTLSDGSVVLNGGRSRRGKLRGPPESREWGN---------ALKGCDDPLFLDFLKQCLEWDPAVRMTPGQALRHPWLR----
26 HHSearch 78.2241%-116 - C1 - - 4YLL DYR1A_HUMAN A:[22-260] -----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------DYIVKNGEKWMDRYEIDSLIGKGSFGQVVKAYDRVEQE-------------------------------------------------------------------------------------WVAIKIIKNKK---AFLNQAQIEVRLLELMNKHDTE-KYYIVHLKRHFMF------RNHLCLVFEMLSYNLYDLLRNTN----FRGVSLNLTRKFAQQMCTALLFLATP--E--LSIIHCDLKPENILLCNP-----------------------K-----------------RSAIKIVDFGSSCQLGQR-------IYQYIQSRFYRSPEVLLG-MPYDLAIDMWSLGCILVEMHTGEPLFSGANEVDQMNKIVEVLG------------------------------------------------------------------------------------------------------------------------------------------
41 HHSearch 77.6932%-124 - C1 - - 3LLT ? A:[24-271] -----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------HFSWKKGMLLNNAFLVIRKMGDGTFGRVLLCQHIDNKK-------------------------------------------------------------------------------------YYAVKVVRNIK---KYTRSAKIEADILKKIQN-DDINNNNIVKYHGKFMY------YDHMCLIFEPLGPSLYEIITRNN----YNGFHIEDIKLYCIEILKALNYL--R--K--MSLTHTDLKPENILLDDPYFEKSLITVRRVTDGKKIQIYRTK-----------------STGIKLIDFGCATFKSDY-------HGSIINTRQYRAPEVILN-LGWDVSSDMWSFGCVLAELYTGSLLFRTHEHMEHLAMM-----------------------------------------------------------------------------------------------------------------------------------------------
27 HHSearch 75.7841%-113 * C1 * - 4YU2 DYR1A_HUMAN A:[22-254] -----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------DYIVKNGEKWMDRYEIDSLIGKGSFGQVVKAYDRVEQE-------------------------------------------------------------------------------------WVAIKIIKNKK---AFLNQAQIEVRLLELMNKHDTEMKYYIVHLKRHFMF------RNHLCLVFEMLSYNLYDLLRNTN----FRGVSLNLTRKFAQQMCTALLFL--ATPE--LSIIHCDLKPENILLCNP-----------------------K-----------------RSAIKIVDFGSSCQLGQR-------IYQYIQSRFYRSPEVLLG-MPYDLAIDMWSLGCILVEMHTGEPLFSGANEVDQMNKIVEVLG------------------------------------------------------------------------------------------------------------------------------------------
28 HHSearch 73.0029% -71 - C1 - - 5BYZ MK07_HUMAN A:[33-303] --------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------QVAIKKIPNAFDVVTNAKRTLRELKILKHFK------HDNIIAIKDILRPTVPYGEFKSVYVVLDLMESDLHQIIHS------SQPLTLEHVRYFLYQLLRGLKYM--H--S--AQVIHRDLKPSNLLVNEN------------------------------------------CELKIGDFGMARGLCTSPAEHQYFMTEYVATRWYRAPELMLSLHEYTQAIDLWSVGCIFGEMLARRQLFPGKNYVHQLQLIMMVLGTPSP-AVIQAV----------GAE--------RVR-------------AYIQSLPP--------------------------R-QPVPWETV------YPGADRQALSLLGRMLRFEPSARISAAAALRHPFLAKY--
38 HHSearch 72.1036%-100 - C1 - - 1Z57 CLK1_HUMAN A:[42-249] --------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------HVAVKIVKNVD---RYCEAARSEIQVLEHLNTTDPNSTFRCVQMLEWFEH------HGHICIVFELLGLSTYDFIKENG----FLPFRLDHIRKMAYQICKSVNFL--H--S--NKLTHTDLKPENILFVQS-----------------------DYTEAYNRDERTLI----NPDIKVVDFGSATYDDEH-------HSTLVSTRHYRAPEVILA-LGWSQPCDVWSIGCILIEYYLGFTVFPTHDSKEHLAMMERI--------------------------------------------------------------------------------------------------------------------------------------------
21 HHSearch 70.9540%-150 - C1 - - 4AZF DYRK2_HUMAN A:[124-318] --------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------HVALKMVRNEK---RFHRQAAEEIRILEHLRKQDKDNTMNVIHMLENFTF------RNHICMTFELLSMNLYELIKKNK----FQGFSLPLVRKFAHSILQCLDAL--H--K--NRIIHCDLKPENILLKQQ-----------------------G-----------------RSGIKVIDFGSSCYEHQR-------VYTYIQSRFYRAPEVILG-ARYGMPIDMWSLGCILAELLTGYPLLPGEDEGDQLACMIELLG------------------------------------------------------------------------------------------------------------------------------------------
22 HHSearch 67.7140%-143 - C1 - - 5LXC DYRK2_HUMAN A:[103-295] --------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------HVALKMVRNEK---RFHRQAAEEIRILEHLRKQDKDNTMNVIHMLENFTF------RNHICMTFELLSMNLYELIKKNK----FQGFSLPLVRKFAHSILQCLDAL--H--K--NRIIHCDLKPENILLKQQ-----------------------G-----------------RSGIKVIDFGSSCYEHQR-------VYTYIQSRFYRAPEVILG-ARYGMPIDMWSLGCILAELLTGYPLLPGEDEGDQLACMIELLG------------------------------------------------------------------------------------------------------------------------------------------
16 PsiBlast_PDB 67.3741% -97 - C1 - - 2WO6 DYR1A_HUMAN A:[82-281] ---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------VAIKIIKNKK---AFLNQAQIEVRLLELMNKHDTEMKYYIVHLKRHFMF------RNHLCLVFEMLSYNLYDLLRNTNFRGVSLNLT----RKFAQQMCTALLFL--A--TPELSIIHCDLKPENILLCNP-----------------------K-----------------RSAIKIVDFGSSCQLGQR-------IYQYIQSRFYRSPEVLLG-MPYDLAIDMWSLGCILVEMHTGEPLFSGANEVDQMNKIVEVLGIP----------------------------------------------------------------------------------------------------------------------------------------
39 HHSearch 66.9536% -93 - C1 - - 5J1W CLK1_HUMAN A:[42-248] --------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------HVAVKIVKNVD---RYCEAARSEIQVLEHLNTTDPNSTFRCVQMLEWFEH------HGHICIVFELLGLSTYDFIKENG----FLPFRLDHIRKMAYQICKSVNFL--H--S--NKLTHTDLKPENILFVQS-----------------------DYTEAYNPKIKRDERTLINPDIKVVDFGSATYDDEH-------HSTLVSTRHYRAPEVILA-LGWSQPCDVWSIGCILIEYYLGFTVFPTHDSKEHLAMMER---------------------------------------------------------------------------------------------------------------------------------------------
9 PsiBlast_PDB 66.7041% -96 - C1 - - 5A3X DYR1A_HUMAN A:[63-263] ---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------VAIKIIKNKK---AFLNQAQIEVRLLELMNKHDTEMKYYIVHLKRHFMF------RNHLCLVFEMLSYNLYDLLRNTNFRGVSLNLT----RKFAQQMCTALLFL--A--TPELSIIHCDLKPENILLCNP-----------------------K-----------------RSAIKIVDFGSSCQLGQR-------IYQYIQSRFYRSPEVLLG-MPYDLAIDMWSLGCILVEMHTGEPLFSGANEVDQMNKIVEVLGIP----------------------------------------------------------------------------------------------------------------------------------------
19 PsiBlast_PDB 66.5541% -95 - C1 - - 4MQ2 DYR1A_HUMAN A:[61-258] ---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------VAIKIIKNKK---AFLNQAQIEVRLLELMNKHDTEMKYYIVHLKRHFMF------RNHLCLVFEMLSYNLYDLLRNTNFRGVSLNLT----RKFAQQMCTALLFL--A--TPELSIIHCDLKPENILLCNP-----------------------K-----------------RSAIKIVDFGSSCQLGQR-------IYQYIQSRFYRSPEVLLG-MPYDLAIDMWSLGCILVEMHTGEPLFSGANEVDQMNKIVEVLGIP----------------------------------------------------------------------------------------------------------------------------------------
20 PsiBlast_PDB 65.9541% -99 - C1 - - 4YLJ DYR1A_HUMAN A:[61-256] ---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------VAIKIIKNKK---AFLNQAQIEVRLLELMNKHDTEMKYYIVHLKRHFMF------RNHLCLVFEMLSYNLYDLLRNTNFRGVSLNLT----RKFAQQMCTALLFL--A--TPELSIIHCDLKPENILLCNP-----------------------K-----------------RSAIKIVDFGSSCQLGQR-------IYQYIQSRFYRSPEVLLG-MPYDLAIDMWSLGCILVEMHTGEPLFSGANEVDQMNKIVEVLGIP----------------------------------------------------------------------------------------------------------------------------------------
8 PsiBlast_PDB 64.9041% -92 - C1 - - 4NCT DYR1A_HUMAN A:[63-263] ---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------VAIKIIKNKK---AFLNQAQIEVRLLELMNKHDTEMKYYIVHLKRHFMF------RNHLCLVFEMLSYNLYDLLRNTNFRGVSLNLT----RKFAQQMCTALLFL--A--TPELSIIHCDLKPENILLCNP-----------------------K-----------------RSAIKIVDFGSSCQLGQR-------IYQYIQSRFYRSPEVLLG-MPYDLAIDMWSLGCILVEMHTGEPLFSGANEVDQMNKIVEVLGIP----------------------------------------------------------------------------------------------------------------------------------------
6 PsiBlast_PDB 64.7841% -96 - C1 - - 3ANQ DYR1A_HUMAN A:[63-263] ---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------VAIKIIKNKK---AFLNQAQIEVRLLELMNKHDTEMKYYIVHLKRHFMF------RNHLCLVFEMLSYNLYDLLRNTNFRGVSLNLT----RKFAQQMCTALLFL--A--TPELSIIHCDLKPENILLCNP-----------------------K-----------------RSAIKIVDFGSSCQLGQR-------IYQYIQSRFYRSPEVLLG-MPYDLAIDMWSLGCILVEMHTGEPLFSGANEVDQMNKIVEVLGIP----------------------------------------------------------------------------------------------------------------------------------------
13 PsiBlast_PDB 64.7641% -97 - C1 - - 5A4T DYR1A_HUMAN A:[63-263] ---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------VAIKIIKNKK---AFLNQAQIEVRLLELMNKHDTEMKYYIVHLKRHFMF------RNHLCLVFEMLSYNLYDLLRNTNFRGVSLNLT----RKFAQQMCTALLFL--A--TPELSIIHCDLKPENILLCNP-----------------------K-----------------RSAIKIVDFGSSCQLGQR-------IYQYIQSRFYRSPEVLLG-MPYDLAIDMWSLGCILVEMHTGEPLFSGANEVDQMNKIVEVLGIP----------------------------------------------------------------------------------------------------------------------------------------