@TOME V2.3
(Mar 2018)
Ref.
-
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Doc.
Global output mode :
Sort entries by :
Atome Result
Tools Result
PDB occurence
Core Structure Cluster
Sequence Color type :
Secondary Structure
Hydrophobicity
Disulfide Bonds
TCoffee Identity Score
Uniprot annotation
Core Structure Cluster
Contacts with Ligands
Show alignment :
Atome selection
All alignments
Only Template with Ligand
Column output:
Score:
Atome Rank Value
Tools Score
Hide column
Alignment:
Sequence Identity (%)
Tcoffee Alignment Score
Hide column
3D Common Core:
Tito PKB Score
Verify3D Score
QMean Score
Hide column
Structural Clustering:
Cluster Num
3D-Jury Struct. Score
Hide column
Modeller Result :
Model Rank
QMean Score
Dfire Score
Dope Score
Errat Score
Verify3D Score
Modeller Score
Hide column
Complexes Modeling
Show Ligands of Templates
Complexes Affinity Score
Main Binding Site Identity
Hide column
Templates Information:
Uniprot entry
Cath class
Scop class
Smart class
Prosite class
Pfam class
EC Number
Taxonomy
Experiment Method
Hide column
Sequence & Result Tab:
PDB Template Sequence
Complexes Tab
Values color: [
Good
|
Correct
|
Middling
|
Bad
]
Sequence color :
Mutated
Helix
Strand
Conserved
Query sequence : B0VQI5: (2017-11-27 )
MSQLKPQEVVRLGDIQMANHLPFVLFGGMNVLESKDLAFEIAETYIDICKRLDIPYVFKASFDKANRSSLHSFRGPGLEKGIEWLGDIKKHFNVPIITDVHEPYQAAPVAEVADIIQLPAFLSRQTDLVEAMAKTQAIINIKKAQFLAPHEMRHILHKCLEVGNDKLILCERGSAFGYNNLVVDMLGFDIMKEMNVPVFFDVTHALQTPGGRSDSAGGRRAQITTLARAGMATGLAGLFLESHPDPDKAKCDGPSALRLSQLEPFLAQLKELDTLVKGFKKLDTH
Atome Classification :
(68 SA)
.........10........20........30........40........50.-.......60........70........80........90........100.......110.......120.......130.......140.......150.......160-------------.......170.......180.......190-.---.--.--....200.......210.......220.......230-.......240.......250.......260.......270.......280...-
(Atome)
(Ident)
(Tito)
(Num)
(QMean)
(Ligand)
(Uniprot)
MSQL
K
P
Q
E
V
V
RLG
D
I
QMANHL
P
F
V
L
FGGMNVLESK
D
L
A
F
E
I
A
E
T
Y
I
D
I
C
K
RL-DI
P
Y
V
F
KASFDKA
N
R
SS
L
H
SFRGP
G
L
E
K
G
I
E
W
L
G
D
I
K
K
HFNV
P
I
I
TDVHEPYQAA
P
V
A
E
V
A
D
I
I
Q
L
P
A
F
L
S
R
Q
T
D
L
V
E
A
M
A
K
T
Q
A
I
I
N
IKKAQFL
A
P
H
E
M
R
H
I
L
H
K
C
L
E
V-------------GN
D
K
L
I
L
C
ERGSAFGYN
N
L
V
V
D
M
L
G
F
D
I
M
K
-E---M--N--V
P
V
F
F
D
V
T
H
A
LQTPGGRSDSAGG
R
R
A
Q
I
T
T
L
A
R
A
G
M
A
-
T
G
L
A
G
L
F
LESHPDPDKAKCDGPSA
L
R
L
S
Q
L
E
P
F
L
A
Q
L
K
E
L
D
T
L
V
K
G
F
K
KLDTH-
9
PsiBlast_PDB
89.60
66%
-88
- C2 -
-
1X6U
1
KDSA_ECOLI
A:
[3-282]
------
Q
K
V
V
S
I
G
D
I
N
V
A
N
D
L
P
F
V
L
F
G
G
M
N
V
L
E
S
R
D
L
A
M
R
I
C
E
H
Y
V
T
V
T
Q
K
L
-
G
I
P
Y
V
F
K
A
S
F
D
K
A
N
R
S
S
I
H
S
Y
R
G
P
G
L
E
E
G
M
K
I
F
Q
E
L
K
Q
T
F
G
V
K
I
I
T
D
V
H
E
P
S
Q
A
Q
P
V
A
D
V
V
D
V
I
Q
L
P
A
F
L
A
R
Q
T
D
L
V
E
A
M
A
K
T
G
A
V
I
N
V
K
K
P
Q
F
V
S
P
G
Q
M
G
N
I
V
D
K
F
K
E
G
-------------
G
N
E
K
V
I
L
C
D
R
G
A
N
F
G
Y
D
N
L
V
V
D
M
L
G
F
S
I
M
K
-
K
---
V
S
G
N
--
S
P
V
I
F
D
V
T
H
A
L
Q
------------
R
A
Q
V
A
E
L
A
R
A
G
M
A
-
V
G
L
A
G
L
F
I
E
A
H
P
D
P
E
H
A
K
C
D
G
P
S
A
L
P
L
A
K
L
E
P
F
L
K
Q
M
K
A
I
D
D
L
V
K
G
F
E
E
L
D
T
--
1
PsiBlast_PDB
89.46
73%
-141
- C2 -
-
4LU0
-
KDSA_PSEAE
A:
[10-282]
-------
K
I
V
R
V
G
D
I
Q
I
G
N
D
L
P
F
V
L
F
G
G
M
N
V
L
E
S
R
D
L
A
M
Q
V
C
E
E
Y
V
R
V
T
E
K
L
-
G
I
P
Y
V
F
K
A
S
F
D
K
A
N
R
S
S
I
H
S
F
R
G
P
G
L
E
E
G
M
K
I
F
E
E
I
K
K
T
F
K
V
P
V
I
T
D
V
H
E
P
F
Q
A
Q
P
V
A
E
V
C
D
I
I
Q
L
P
A
F
L
S
R
Q
T
D
L
V
V
A
M
A
R
T
N
A
V
I
N
I
K
K
A
Q
F
L
A
P
Q
E
M
K
H
I
L
T
K
C
E
E
A
-------------
G
N
D
R
L
I
L
C
E
R
G
S
S
F
G
Y
N
N
L
V
V
D
M
L
G
F
G
I
M
K
-
Q
---
F
--
E
--
Y
P
V
F
F
D
V
T
H
A
L
------------
R
R
A
Q
V
T
D
L
A
K
A
G
L
S
-
Q
K
L
A
G
L
F
L
E
A
H
P
--------------
L
N
K
L
E
A
F
L
S
Q
L
K
Q
L
D
E
L
I
K
S
F
P
------
64
PsiBlast_CBE
87.69
61%
-105
- C2 -
-
3FYO
1
KDSA_NEIMB
D:
[3-272]
---------
I
K
I
N
D
I
T
L
G
N
N
S
P
F
V
L
F
G
G
I
C
V
L
E
S
L
D
S
T
L
Q
T
C
A
H
Y
V
E
V
T
R
K
L
-
G
I
P
Y
I
F
K
A
S
F
D
K
A
N
R
S
S
I
H
S
Y
R
G
V
G
L
E
E
G
L
K
I
F
E
K
V
K
A
E
F
G
I
P
V
I
T
D
V
H
E
P
H
Q
C
Q
P
V
A
E
V
C
D
V
I
Q
L
P
A
F
L
A
R
Q
T
D
L
V
V
A
M
A
K
T
G
N
V
V
N
I
K
K
P
Q
F
L
S
P
S
Q
M
K
N
I
V
E
K
F
H
E
A
-------------
G
N
G
K
L
I
L
C
E
R
G
S
S
F
G
Y
D
N
L
V
V
D
M
L
G
F
G
V
M
K
-
Q
---
T
CG
N
--
L
P
V
I
F
D
V
T
H
S
L
Q
T
----------
R
R
A
Q
A
L
D
L
A
L
A
G
M
A
-
T
R
L
A
G
L
F
L
E
S
H
P
------
C
E
G
A
S
A
L
P
L
H
L
L
E
D
F
L
I
R
I
K
A
L
D
D
L
I
K
---------
163
Fugue
87.53
68%
-93
- C2 -
-
1D9E
-
KDSA_ECOLI
A:
[1-284]
----
M
K
Q
K
V
V
S
I
G
D
I
N
V
A
N
D
L
P
F
V
L
F
G
G
M
N
V
L
E
S
R
D
L
A
M
R
I
C
E
H
Y
V
T
V
T
Q
K
L
-
G
I
P
Y
V
F
K
A
S
F
D
K
A
N
R
S
S
I
H
S
Y
R
G
P
G
L
E
E
G
M
K
I
F
Q
E
L
K
Q
T
F
G
V
K
I
I
T
D
V
H
E
P
S
Q
A
Q
P
V
A
D
V
V
D
V
I
Q
L
P
A
F
L
A
R
Q
T
D
L
V
E
A
M
A
K
T
G
A
V
I
N
V
K
K
P
Q
F
V
S
P
G
Q
M
G
N
I
V
D
K
F
K
E
G
-------------
G
N
E
K
V
I
L
C
D
R
G
A
N
F
G
Y
D
N
L
V
V
D
M
L
G
F
S
I
M
K
-
K
---
V
S
G
N
--
S
P
V
I
F
D
V
T
H
A
L
Q
------------
R
A
Q
V
A
E
L
A
R
A
G
M
A
-
V
G
L
A
G
L
F
I
E
A
H
P
D
P
------
E
P
S
A
L
P
L
A
K
L
E
P
F
L
K
Q
M
K
A
I
D
D
L
V
K
G
F
E
E
L
D
T
S
K
3
PsiBlast_PDB
87.26
66%
-88
- C2 -
-
1GG0
-
KDSA_ECOLI
A:
[3-282]
------
Q
K
V
V
S
I
G
D
I
N
V
A
N
D
L
P
F
V
L
F
G
G
M
N
V
L
E
S
R
D
L
A
M
R
I
C
E
H
Y
V
T
V
T
Q
K
L
-
G
I
P
Y
V
F
K
A
S
F
D
K
A
N
R
S
S
I
H
S
Y
R
G
P
G
L
E
E
G
M
K
I
F
Q
E
L
K
Q
T
F
G
V
K
I
I
T
D
V
H
E
P
S
Q
A
Q
P
V
A
D
V
V
D
V
I
Q
L
P
A
F
L
A
R
Q
T
D
L
V
E
A
M
A
K
T
G
A
V
I
N
V
K
K
P
Q
F
V
S
P
G
Q
M
G
N
I
V
D
K
F
K
E
G
-------------
G
N
E
K
V
I
L
C
D
R
G
A
N
F
G
Y
D
N
L
V
V
D
M
L
G
F
S
I
M
K
-
K
---
V
S
G
N
--
S
P
V
I
F
D
V
T
H
A
L
Q
C
R
---------
R
R
A
Q
V
A
E
L
A
R
A
G
M
A
-
V
G
L
A
G
L
F
I
E
A
H
P
D
P
E
H
A
K
C
D
G
P
S
A
L
P
L
A
K
L
E
P
F
L
K
Q
M
K
A
I
D
D
L
V
K
G
F
E
E
L
D
T
--
7
PsiBlast_PDB
87.25
66%
-88
- C2 -
-
1PL9
1
KDSA_ECOLI
A:
[3-282]
------
Q
K
V
V
S
I
G
D
I
N
V
A
N
D
L
P
F
V
L
F
G
G
M
N
V
L
E
S
R
D
L
A
M
R
I
C
E
H
Y
V
T
V
T
Q
K
L
-
G
I
P
Y
V
F
K
A
S
F
D
K
A
N
R
S
S
I
H
S
Y
R
G
P
G
L
E
E
G
M
K
I
F
Q
E
L
K
Q
T
F
G
V
K
I
I
T
D
V
H
E
P
S
Q
A
Q
P
V
A
D
V
V
D
V
I
Q
L
P
A
F
L
A
R
Q
T
D
L
V
E
A
M
A
K
T
G
A
V
I
N
V
K
K
P
Q
F
V
S
P
G
Q
M
G
N
I
V
D
K
F
K
E
G
-------------
G
N
E
K
V
I
L
C
D
R
G
A
N
F
G
Y
D
N
L
V
V
D
M
L
G
F
S
I
M
K
-
K
---
V
S
G
N
--
S
P
V
I
F
D
V
T
H
A
L
Q
------------
R
A
Q
V
A
E
L
A
R
A
G
M
A
-
V
G
L
A
G
L
F
I
E
A
H
P
D
P
E
H
A
K
C
D
G
P
S
A
L
P
L
A
K
L
E
P
F
L
K
Q
M
K
A
I
D
D
L
V
K
G
F
E
E
L
D
T
--
184
HHSearch
87.07
62%
-91
- C2 -
-
3STG
-
KDSA_NEIMB
B:
[1-266]
-------
M
D
I
K
I
N
D
I
T
L
G
N
N
S
P
F
V
L
F
G
G
I
N
V
L
E
S
L
D
S
T
L
Q
T
C
A
H
Y
V
E
V
T
R
K
L
-
G
I
P
Y
I
F
K
A
S
F
D
K
-
P
R
S
S
I
H
S
Y
R
G
V
G
L
E
E
G
L
K
I
F
E
K
V
K
A
E
F
G
I
P
V
I
T
D
V
H
E
P
H
Q
C
Q
P
V
A
E
V
C
D
V
I
Q
L
P
A
F
L
A
R
Q
T
D
L
V
V
A
M
A
K
T
G
N
V
V
N
I
K
K
P
Q
F
L
S
P
S
Q
M
K
N
I
V
E
K
F
H
E
A
-------------
G
N
G
K
L
I
L
C
E
R
G
S
S
F
G
Y
D
N
L
V
V
D
M
L
G
F
G
V
M
K
Q
T
---
C
G-
N
--
L
P
V
I
F
D
V
T
H
S
-----------
L
G
R
R
A
Q
A
L
D
L
A
L
A
G
M
A
-
T
R
L
A
G
L
F
L
E
S
H
P
D
P
K
L
A
K
C
D
G
P
S
A
L
P
L
H
L
L
E
D
F
L
I
R
I
K
A
L
D
D
L
I
K
S
Q
P
I
L
T
---
6
PsiBlast_PDB
86.88
66%
-86
- C2 -
-
1PHW
1
KDSA_ECOLI
A:
[3-282]
------
Q
K
V
V
S
I
G
D
I
N
V
A
N
D
L
P
F
V
L
F
G
G
M
N
V
L
E
S
R
D
L
A
M
R
I
C
E
H
Y
V
T
V
T
Q
K
L
-
G
I
P
Y
V
F
K
A
S
F
D
K
A
N
R
S
S
I
H
S
Y
R
G
P
G
L
E
E
G
M
K
I
F
Q
E
L
K
Q
T
F
G
V
K
I
I
T
D
V
H
E
P
S
Q
A
Q
P
V
A
D
V
V
D
V
I
Q
L
P
A
F
L
A
R
Q
T
D
L
V
E
A
M
A
K
T
G
A
V
I
N
V
K
K
P
Q
F
V
S
P
G
Q
M
G
N
I
V
D
K
F
K
E
G
-------------
G
N
E
K
V
I
L
C
D
R
G
A
N
F
G
Y
D
N
L
V
V
D
M
L
G
F
S
I
M
K
-
K
---
V
S
G
N
--
S
P
V
I
F
D
V
T
H
A
L
Q
------------
R
A
Q
V
A
E
L
A
R
A
G
M
A
-
V
G
L
A
G
L
F
I
E
A
H
P
D
P
E
H
A
K
C
D
G
P
S
A
L
P
L
A
K
L
E
P
F
L
K
Q
M
K
A
I
D
D
L
V
K
G
F
E
E
L
D
T
--
5
PsiBlast_PDB
86.53
66%
-83
- C2 -
-
1PHQ
1
KDSA_ECOLI
A:
[3-282]
------
Q
K
V
V
S
I
G
D
I
N
V
A
N
D
L
P
F
V
L
F
G
G
M
N
V
L
E
S
R
D
L
A
M
R
I
C
E
H
Y
V
T
V
T
Q
K
L
-
G
I
P
Y
V
F
K
A
S
F
D
K
A
N
R
S
S
I
H
S
Y
R
G
P
G
L
E
E
G
M
K
I
F
Q
E
L
K
Q
T
F
G
V
K
I
I
T
D
V
H
E
P
S
Q
A
Q
P
V
A
D
V
V
D
V
I
Q
L
P
A
F
L
A
R
Q
T
D
L
V
E
A
M
A
K
T
G
A
V
I
N
V
K
K
P
Q
F
V
S
P
G
Q
M
G
N
I
V
D
K
F
K
E
G
-------------
G
N
E
K
V
I
L
C
D
R
G
A
N
F
G
Y
D
N
L
V
V
D
M
L
G
F
S
I
M
K
-
K
---
V
S
G
N
--
S
P
V
I
F
D
V
T
H
A
L
Q
------------
R
A
Q
V
A
E
L
A
R
A
G
M
A
-
V
G
L
A
G
L
F
I
E
A
H
P
D
P
E
H
A
K
C
D
G
P
S
A
L
P
L
A
K
L
E
P
F
L
K
Q
M
K
A
I
D
D
L
V
K
G
F
E
E
L
D
T
--
18
PsiBlast_PDB
86.51
62%
-118
- C2 -
-
3STE
-
KDSA_NEIMB
A:
[3-272]
---------
I
K
I
N
D
I
T
L
G
N
N
S
P
F
V
L
F
G
G
I
N
V
L
E
S
L
D
S
T
L
Q
T
C
A
H
Y
V
E
V
T
R
K
L
-
G
I
P
Y
I
F
K
A
S
F
D
K
A
N
R
S
S
I
H
S
Y
R
G
V
G
L
E
E
G
L
K
I
F
E
K
V
K
A
E
F
G
I
P
V
I
T
D
V
H
E
P
H
Q
C
Q
P
V
A
E
V
C
D
V
I
Q
L
P
A
F
L
A
R
Q
T
D
L
V
V
A
M
A
K
T
G
N
V
V
N
I
K
K
P
Q
F
L
S
P
S
Q
M
K
N
I
V
E
K
F
H
E
A
-------------
G
N
G
K
L
I
L
C
E
R
G
S
S
F
G
Y
D
N
L
V
V
D
M
L
G
F
G
V
M
K
-
Q
---
T
C
G
N
--
L
P
V
I
F
D
V
T
H
S
L
A
---------
G
G
R
R
A
Q
A
L
D
L
A
L
A
G
M
A
-
T
R
L
A
G
L
F
L
E
-----------------
L
H
L
L
E
D
F
L
I
R
I
K
A
L
D
D
L
I
K
---------
11
PsiBlast_PDB
86.45
66%
-87
- C2 -
-
1G7U
1
KDSA_ECOLI
A:
[3-282]
------
Q
K
V
V
S
I
G
D
I
N
V
A
N
D
L
P
F
V
L
F
G
G
M
N
V
L
E
S
R
D
L
A
M
R
I
C
E
H
Y
V
T
V
T
Q
K
L
-
G
I
P
Y
V
F
K
A
S
F
D
K
A
N
R
S
S
I
H
S
Y
R
G
P
G
L
E
E
G
M
K
I
F
Q
E
L
K
Q
T
F
G
V
K
I
I
T
D
V
H
E
P
S
Q
A
Q
P
V
A
D
V
V
D
V
I
Q
L
P
A
F
L
A
R
Q
T
D
L
V
E
A
M
A
K
T
G
A
V
I
N
V
K
K
P
Q
F
V
S
P
G
Q
M
G
N
I
V
D
K
F
K
E
G
-------------
G
N
E
K
V
I
L
C
D
R
G
A
N
F
G
Y
D
N
L
V
V
D
M
L
G
F
S
I
M
K
-
K
---
V
S
G
N
--
S
P
V
I
F
D
V
T
H
A
L
Q
C
R
D
P
F
V
A
A
S
G
G
R
R
A
Q
V
A
E
L
A
R
A
G
M
A
-
V
G
L
A
G
L
F
I
E
A
H
P
D
P
E
H
A
K
C
D
G
P
S
A
L
P
L
A
K
L
E
P
F
L
K
Q
M
K
A
I
D
D
L
V
K
G
F
E
E
L
D
T
--
72
PsiBlast_CBE
86.43
61%
-113
- C2 -
-
3FYP
2
KDSA_NEIMB
B:
[3-272]
---------
I
K
I
N
D
I
T
L
G
N
N
S
P
F
V
L
F
G
G
I
C
V
L
E
S
L
D
S
T
L
Q
T
C
A
H
Y
V
E
V
T
R
K
L
-
G
I
P
Y
I
F
K
A
S
F
D
K
A
N
R
S
S
I
H
S
Y
R
G
V
G
L
E
E
G
L
K
I
F
E
K
V
K
A
E
F
G
I
P
V
I
T
D
V
H
E
P
H
Q
C
Q
P
V
A
E
V
C
D
V
I
Q
L
P
A
F
L
A
R
Q
T
D
L
V
V
A
M
A
K
T
G
N
V
V
N
I
K
K
P
Q
F
L
S
P
S
Q
M
K
N
I
V
E
K
F
H
E
A
-------------
G
N
G
K
L
I
L
C
E
R
G
S
S
F
G
Y
D
N
L
V
V
D
M
L
G
F
G
V
M
K
-
Q
---
T
C
G
N
--
L
P
V
I
F
D
V
T
H
S
L
Q
---------
G
G
R
R
A
Q
A
L
D
L
A
L
A
G
M
A
-
T
R
L
A
G
L
F
L
E
S
H
-----------------
L
L
E
D
F
L
I
R
I
K
A
L
D
D
L
I
K
---------
8
PsiBlast_PDB
86.32
66%
-88
- C2 -
-
1Q3N
1
KDSA_ECOLI
A:
[3-282]
------
Q
K
V
V
S
I
G
D
I
N
V
A
N
D
L
P
F
V
L
F
G
G
M
N
V
L
E
S
R
D
L
A
M
R
I
C
E
H
Y
V
T
V
T
Q
K
L
-
G
I
P
Y
V
F
K
A
S
F
D
K
A
N
R
S
S
I
H
S
Y
R
G
P
G
L
E
E
G
M
K
I
F
Q
E
L
K
Q
T
F
G
V
K
I
I
T
D
V
H
E
P
S
Q
A
Q
P
V
A
D
V
V
D
V
I
Q
L
P
A
F
L
A
R
Q
T
D
L
V
E
A
M
A
K
T
G
A
V
I
N
V
K
K
P
Q
F
V
S
P
G
Q
M
G
N
I
V
D
K
F
K
E
G
-------------
G
N
E
K
V
I
L
C
D
R
G
A
N
F
G
Y
D
N
L
V
V
D
M
L
G
F
S
I
M
K
-
K
---
V
SG
N
--
S
P
V
I
F
D
V
T
H
A
L
Q
------------
R
A
Q
V
A
E
L
A
R
A
G
M
A
-
V
G
L
A
G
L
F
I
E
A
H
P
D
P
E
H
A
K
C
D
G
P
S
A
L
P
L
A
K
L
E
P
F
L
K
Q
M
K
A
I
D
D
L
V
K
G
F
E
E
L
D
T
--
174
HHSearch
86.27
67%
-86
- C2 -
-
1G7U
1
KDSA_ECOLI
A:
[2-282]
-----
K
Q
K
V
V
S
I
G
D
I
N
V
A
N
D
L
P
F
V
L
F
G
G
M
N
V
L
E
S
R
D
L
A
M
R
I
C
E
H
Y
V
T
V
T
Q
K
L
-
G
I
P
Y
V
F
K
A
S
F
D
K
A
N
R
S
S
I
H
S
Y
R
G
P
G
L
E
E
G
M
K
I
F
Q
E
L
K
Q
T
F
G
V
K
I
I
T
D
V
H
E
P
S
Q
A
Q
P
V
A
D
V
V
D
V
I
Q
L
P
A
F
L
A
R
Q
T
D
L
V
E
A
M
A
K
T
G
A
V
I
N
V
K
K
P
Q
F
V
S
P
G
Q
M
G
N
I
V
D
K
F
K
E
G
-------------
G
N
E
K
V
I
L
C
D
R
G
A
N
F
G
Y
D
N
L
V
V
D
M
L
G
F
S
I
M
K
K
V
---
S
G
-
N
--
S
P
V
I
F
D
V
T
H
A
L
Q
C
R
D
P
F
V
A
A
S
G
G
R
R
A
Q
V
A
E
L
A
R
A
G
M
A
-
V
G
L
A
G
L
F
I
E
A
H
P
D
P
E
H
A
K
C
D
G
P
S
A
L
P
L
A
K
L
E
P
F
L
K
Q
M
K
A
I
D
D
L
V
K
G
F
E
E
L
D
T
--
2
PsiBlast_PDB
86.24
66%
-94
- C2 -
-
1D9E
-
KDSA_ECOLI
A:
[3-282]
------
Q
K
V
V
S
I
G
D
I
N
V
A
N
D
L
P
F
V
L
F
G
G
M
N
V
L
E
S
R
D
L
A
M
R
I
C
E
H
Y
V
T
V
T
Q
K
L
-
G
I
P
Y
V
F
K
A
S
F
D
K
A
N
R
S
S
I
H
S
Y
R
G
P
G
L
E
E
G
M
K
I
F
Q
E
L
K
Q
T
F
G
V
K
I
I
T
D
V
H
E
P
S
Q
A
Q
P
V
A
D
V
V
D
V
I
Q
L
P
A
F
L
A
R
Q
T
D
L
V
E
A
M
A
K
T
G
A
V
I
N
V
K
K
P
Q
F
V
S
P
G
Q
M
G
N
I
V
D
K
F
K
E
G
-------------
G
N
E
K
V
I
L
C
D
R
G
A
N
F
G
Y
D
N
L
V
V
D
M
L
G
F
S
I
M
K
-
K
---
V
S
G
N
--
S
P
V
I
F
D
V
T
H
A
L
Q
------------
R
A
Q
V
A
E
L
A
R
A
G
M
A
-
V
G
L
A
G
L
F
I
E
A
H
P
D
P
E
------
P
S
A
L
P
L
A
K
L
E
P
F
L
K
Q
M
K
A
I
D
D
L
V
K
G
F
E
E
L
D
T
--
70
PsiBlast_CBE
86.23
61%
-113
- C2 -
-
3FYP
1
KDSA_NEIMB
D:
[3-272]
---------
I
K
I
N
D
I
T
L
G
N
N
S
P
F
V
L
F
G
G
I
C
V
L
E
S
L
D
S
T
L
Q
T
C
A
H
Y
V
E
V
T
R
K
L
-
G
I
P
Y
I
F
K
A
S
F
D
K
A
N
R
S
S
I
--
Y
R
G
V
G
L
E
E
G
L
K
I
F
E
K
V
K
A
E
F
G
I
P
V
I
T
D
V
H
E
P
H
Q
C
Q
P
V
A
E
V
C
D
V
I
Q
L
P
A
F
L
A
R
Q
T
D
L
V
V
A
M
A
K
T
G
N
V
V
N
I
K
K
P
Q
F
L
S
P
S
Q
M
K
N
I
V
E
K
F
H
E
A
-------------
G
N
G
K
L
I
L
C
E
R
G
S
S
F
G
Y
D
N
L
V
V
D
M
L
G
F
G
V
M
K
-
Q
---
T
CG
N
--
L
P
V
I
F
D
V
T
H
S
L
Q
T
---------
G
R
R
A
Q
A
L
D
L
A
L
A
G
M
A
-
T
R
L
A
G
L
F
L
E
S
H
P
-----------
A
L
P
L
H
L
L
E
D
F
L
I
R
I
K
A
L
D
D
L
I
K
---------
16
PsiBlast_PDB
85.88
62%
-119
- C2 -
-
4JTK
-
KDSA_NEIMB
A:
[3-272]
---------
I
K
I
N
D
I
T
L
G
N
N
S
P
F
V
L
F
G
G
I
N
V
L
E
S
L
D
S
T
L
Q
T
C
A
H
Y
V
E
V
T
R
K
L
-
G
I
P
Y
I
F
K
A
S
F
D
K
A
N
R
S
S
I
H
S
Y
R
G
V
G
L
E
E
G
L
K
I
F
E
K
V
K
A
E
F
G
I
P
V
I
T
D
V
H
E
P
H
Q
C
Q
P
V
A
E
V
C
D
V
I
Q
L
P
A
F
L
A
Q
Q
T
D
L
V
V
A
M
A
K
T
G
N
V
V
N
I
K
K
P
Q
F
L
S
P
S
Q
M
K
N
I
V
E
K
F
H
E
A
-------------
G
N
G
K
L
I
L
C
E
R
G
S
S
F
G
Y
D
N
L
V
V
D
M
L
G
F
G
V
M
K
-
Q
---
T
C
G
N
--
L
P
V
I
F
D
V
T
H
S
L
Q
T
R
--------
G
R
R
A
Q
A
L
D
L
A
L
A
G
M
A
-
T
R
L
A
G
L
F
L
E
-----------------
L
H
L
L
E
D
F
L
I
R
I
K
A
L
D
D
L
I
K
---------
41
PsiBlast_CBE
85.85
62%
-103
- C2 -
-
4JTF
1
KDSA_NEIMB
B:
[3-272]
---------
I
K
I
N
D
I
T
L
G
N
N
S
P
F
V
L
F
G
G
I
N
V
L
E
S
L
D
S
T
L
Q
T
C
A
H
Y
V
E
V
T
R
K
L
-
G
I
P
Y
I
F
K
A
S
F
D
K
A
N
R
S
S
I
H
S
Y
R
G
V
G
L
E
E
G
L
K
I
F
E
K
V
K
A
E
F
G
I
P
V
I
T
D
V
H
E
P
H
Q
C
Q
P
V
A
E
V
C
D
V
I
Q
L
P
A
R
L
A
R
Q
T
D
L
V
V
A
M
A
K
T
G
N
V
V
N
I
K
K
P
Q
F
L
S
P
S
Q
M
K
N
I
V
E
K
F
H
E
A
-------------
G
N
G
K
L
I
L
C
E
R
G
S
S
F
G
Y
D
N
L
V
V
D
M
L
G
F
G
V
M
K
-
Q
---
T
CG
N
--
L
P
V
I
F
D
V
T
H
S
L
Q
T
R
D
A
G
S
A
A
S
G
G
R
R
A
Q
A
L
D
L
A
L
A
G
M
A
-
T
R
L
A
G
L
F
L
E
S
H
P
-----------
A
L
P
L
H
L
L
E
D
F
L
I
R
I
K
A
L
D
D
L
I
K
---------
19
PsiBlast_PDB
85.74
62%
-109
- C2 -
-
3QPZ
-
KDSA_NEIMB
A:
[3-272]
---------
I
K
I
N
D
I
T
L
G
N
N
S
P
F
V
L
F
G
G
I
N
V
L
E
S
L
D
S
T
L
Q
T
C
A
H
Y
V
E
V
T
R
K
L
-
G
I
P
Y
I
F
K
A
S
F
D
K
A
A
R
S
S
I
H
S
Y
R
G
V
G
L
E
E
G
L
K
I
F
E
K
V
K
A
E
F
G
I
P
V
I
T
D
V
H
E
P
H
Q
C
Q
P
V
A
E
V
C
D
V
I
Q
L
P
A
F
L
A
R
Q
T
D
L
V
V
A
M
A
K
T
G
N
V
V
N
I
K
K
P
Q
F
L
S
P
S
Q
M
K
N
I
V
E
K
F
H
E
A
-------------
G
N
G
K
L
I
L
C
E
R
G
S
S
F
G
Y
D
N
L
V
V
D
M
L
G
F
G
V
M
K
-
Q
---
T
C
G
N
--
L
P
V
I
F
D
V
T
H
S
L
Q
----------
G
R
R
A
Q
A
L
D
L
A
L
A
G
M
A
-
T
R
L
A
G
L
F
L
E
S
---------------
P
L
H
L
L
E
D
F
L
I
R
I
K
A
L
D
D
L
I
K
---------
35
PsiBlast_CBE
85.16
62%
-110
- C2 -
-
3QPZ
2
KDSA_NEIMB
D:
[3-272]
---------
I
K
I
N
D
I
T
L
G
N
N
S
P
F
V
L
F
G
G
I
N
V
L
E
S
L
D
S
T
L
Q
T
C
A
H
Y
V
E
V
T
R
K
L
-
G
I
P
Y
I
F
K
A
S
F
D
K
A
A
R
S
S
I
H
S
Y
R
G
V
G
L
E
E
G
L
K
I
F
E
K
V
K
A
E
F
G
I
P
V
I
T
D
V
H
E
P
H
Q
C
Q
P
V
A
E
V
C
D
V
I
Q
L
P
A
F
L
A
R
Q
T
D
L
V
V
A
M
A
K
T
G
N
V
V
N
I
K
K
P
Q
F
L
S
P
S
Q
M
K
N
I
V
E
K
F
H
E
A
-------------
G
N
G
K
L
I
L
C
E
R
G
S
S
F
G
Y
D
N
L
V
V
D
M
L
G
F
G
V
M
K
-
Q
---
T
CG
N
--
L
P
V
I
F
D
V
T
H
S
L
Q
T
------------
A
Q
A
L
D
L
A
L
A
G
M
A
-
T
R
L
A
G
L
F
L
E
S
H
-----------
S
A
L
P
L
H
L
L
E
D
F
L
I
R
I
K
A
L
D
D
L
I
K
---------
79
PsiBlast_CBE
83.60
62%
-108
- C2 -
-
3STF
1
KDSA_NEIMB
B:
[3-272]
---------
I
K
I
N
D
I
T
L
G
N
N
S
P
F
V
L
F
G
G
I
N
V
L
E
S
L
D
S
T
L
Q
T
C
A
H
Y
V
E
V
T
R
K
L
-
G
I
P
Y
I
F
K
A
S
F
D
K
A
N
R
S
S
I
H
S
Y
R
G
V
G
L
E
E
G
L
K
I
F
E
K
V
K
A
E
F
G
I
P
V
I
T
D
V
H
E
P
H
Q
C
Q
P
V
A
E
V
C
D
V
I
Q
L
P
A
F
L
A
R
Q
T
D
L
V
V
A
M
A
K
T
G
N
V
V
N
I
K
K
P
Q
F
L
S
P
S
Q
M
K
N
I
V
E
K
F
H
E
A
-------------
G
N
G
K
L
I
L
C
E
R
G
S
S
F
G
Y
D
N
L
V
V
D
M
L
G
F
G
V
M
K
-
Q
---
T
CG
N
--
L
P
V
I
F
D
V
T
H
S
L
Q
----------
G
R
R
A
Q
A
L
D
L
A
L
A
G
M
A
-
T
R
L
A
G
L
F
L
E
S
H
-----------------
L
L
E
D
F
L
I
R
I
K
A
L
D
D
L
I
K
---------
59
PsiBlast_CBE
83.05
58%
-78
- C2 -
-
3TMQ
4
?
A:
[13-283]
--------------
V
T
A
G
N
S
L
P
F
V
L
F
G
G
I
N
V
L
E
S
L
D
F
T
L
D
V
C
G
E
Y
V
A
V
T
R
K
L
-
G
I
P
F
V
F
K
A
S
F
D
K
A
N
R
S
S
I
H
S
Y
R
G
V
G
L
D
E
G
L
K
I
F
A
E
V
K
A
R
F
G
V
P
V
I
T
D
V
H
E
A
E
Q
A
A
P
V
A
E
I
A
D
V
L
Q
V
P
A
F
L
A
R
Q
T
D
L
V
V
A
I
A
K
A
G
K
P
V
N
V
K
K
P
Q
F
M
S
P
T
Q
L
K
H
V
V
S
K
C
G
E
V
-------------
G
N
D
R
V
M
L
C
E
R
G
S
S
F
G
Y
D
N
L
V
V
D
M
L
G
F
R
Q
M
A
-
E
---
T
--
T
GG
C
P
V
I
F
D
V
T
H
S
L
Q
C
R
D
P
L
G
D
A
S
G
G
R
R
R
Q
V
L
D
L
A
R
A
G
I
A
-
V
G
I
A
G
L
F
L
E
A
H
P
D
P
D
R
A
R
C
D
G
P
S
A
L
P
L
H
Q
L
E
G
L
L
S
Q
M
K
A
I
D
D
L
V
K
R
M
P
A
L
E
---
55
PsiBlast_CBE
82.66
58%
-78
- C2 -
-
3UND
5
?
B:
[13-283]
--------------
V
T
A
G
N
S
L
P
F
V
L
F
G
G
I
N
V
L
E
S
L
D
F
T
L
D
V
C
G
E
Y
V
A
V
T
R
K
L
-
G
I
P
F
V
F
K
A
S
F
D
K
A
N
R
S
S
I
H
S
Y
R
G
V
G
L
D
E
G
L
K
I
F
A
E
V
K
A
R
F
G
V
P
V
I
T
D
V
H
E
A
E
Q
A
A
P
V
A
E
I
A
D
V
L
Q
V
P
A
F
L
A
R
Q
T
D
L
V
V
A
I
A
K
A
G
K
P
V
N
V
K
K
P
Q
F
M
S
P
T
Q
L
K
H
V
V
S
K
C
G
E
V
-------------
G
N
D
R
V
M
L
C
E
R
G
S
S
F
G
Y
D
N
L
V
V
D
M
L
G
F
R
Q
M
A
-
E
---
T
--
T
GG
C
P
V
I
F
D
V
T
H
S
L
Q
C
R
D
P
L
G
D
A
S
G
G
R
R
R
Q
V
L
D
L
A
R
A
G
I
A
-
V
G
I
A
G
L
F
L
E
A
H
P
D
P
D
R
A
R
C
D
G
P
S
A
L
P
L
H
Q
L
E
G
L
L
S
Q
M
K
A
I
D
D
L
V
K
R
M
P
A
L
E
---
4
PsiBlast_PDB
82.64
66%
-89
- C2 -
-
1G7V
1
KDSA_ECOLI
A:
[3-282]
------
Q
K
V
V
S
I
G
D
I
N
V
A
N
D
L
P
F
V
L
F
G
G
M
N
V
L
E
S
R
D
L
A
M
R
I
C
E
H
Y
V
T
V
T
Q
K
L
-
G
I
P
Y
V
F
K
A
S
F
D
K
A
N
R
S
S
I
H
S
Y
R
G
P
G
L
E
E
G
M
K
I
F
Q
E
L
K
Q
T
F
G
V
K
I
I
T
D
V
H
E
P
S
Q
A
Q
P
V
A
D
V
V
D
V
I
Q
L
P
A
F
L
A
R
Q
T
D
L
V
E
A
M
A
K
T
G
A
V
I
N
V
K
K
P
Q
F
V
S
P
G
Q
M
G
N
I
V
D
K
F
K
E
G
-------------
G
N
E
K
V
I
L
C
D
R
G
A
N
F
G
Y
D
N
L
V
V
D
M
L
G
F
S
I
M
K
-
K
---
V
S
G
N
--
S
P
V
I
F
D
V
T
H
A
L
Q
C
R
D
P
F
G
A
A
S
G
G
R
R
A
Q
V
A
E
L
A
R
A
G
M
A
-
V
G
L
A
G
L
F
I
E
A
H
P
D
P
E
H
A
K
C
D
G
P
S
A
L
P
L
A
K
L
E
P
F
L
K
Q
M
K
A
I
D
D
L
V
K
G
F
E
E
L
D
T
--
54
PsiBlast_CBE
82.44
58%
-79
- C2 -
-
3UND
6
?
C:
[13-283]
--------------
V
T
A
G
N
S
L
P
F
V
L
F
G
G
I
N
V
L
E
S
L
D
F
T
L
D
V
C
G
E
Y
V
A
V
T
R
K
L
-
G
I
P
F
V
F
K
A
S
F
D
K
A
N
R
S
S
I
H
S
Y
R
G
V
G
L
D
E
G
L
K
I
F
A
E
V
K
A
R
F
G
V
P
V
I
T
D
V
H
E
A
E
Q
A
A
P
V
A
E
I
A
D
V
L
Q
V
P
A
F
L
A
R
Q
T
D
L
V
V
A
I
A
K
A
G
K
P
V
N
V
K
K
P
Q
F
M
S
P
T
Q
L
K
H
V
V
S
K
C
G
E
V
-------------
G
N
D
R
V
M
L
C
E
R
G
S
S
F
G
Y
D
N
L
V
V
D
M
L
G
F
R
Q
M
A
-
E
---
T
--
T
GG
C
P
V
I
F
D
V
T
H
S
L
Q
C
R
D
P
L
G
D
A
S
G
G
R
R
R
Q
V
L
D
L
A
R
A
G
I
A
-
V
G
I
A
G
L
F
L
E
A
H
P
D
P
D
R
A
R
C
D
G
P
S
A
L
P
L
H
Q
L
E
G
L
L
S
Q
M
K
A
I
D
D
L
V
K
R
M
P
A
L
E
---
56
PsiBlast_CBE
82.26
58%
-75
- C2 -
-
3UND
6
?
A:
[13-283]
--------------
V
T
A
G
N
S
L
P
F
V
L
F
G
G
I
N
V
L
E
S
L
D
F
T
L
D
V
C
G
E
Y
V
A
V
T
R
K
L
-
G
I
P
F
V
F
K
A
S
F
D
K
A
N
R
S
S
I
H
S
Y
R
G
V
G
L
D
E
G
L
K
I
F
A
E
V
K
A
R
F
G
V
P
V
I
T
D
V
H
E
A
E
Q
A
A
P
V
A
E
I
A
D
V
L
Q
V
P
A
F
L
A
R
Q
T
D
L
V
V
A
I
A
K
A
G
K
P
V
N
V
K
K
P
Q
F
M
S
P
T
Q
L
K
H
V
V
S
K
C
G
E
V
-------------
G
N
D
R
V
M
L
C
E
R
G
S
S
F
G
Y
D
N
L
V
V
D
M
L
G
F
R
Q
M
A
-
E
---
T
--
T
GG
C
P
V
I
F
D
V
T
H
S
L
Q
C
R
D
P
L
G
D
A
S
G
G
R
R
R
Q
V
L
D
L
A
R
A
G
I
A
-
V
G
I
A
G
L
F
L
E
A
H
P
D
P
D
R
A
R
C
D
G
P
S
A
L
P
L
H
Q
L
E
G
L
L
S
Q
M
K
A
I
D
D
L
V
K
R
M
P
A
L
E
---
57
PsiBlast_CBE
82.20
58%
-75
- C2 -
-
3TMQ
4
?
C:
[13-283]
--------------
V
T
A
G
N
S
L
P
F
V
L
F
G
G
I
N
V
L
E
S
L
D
F
T
L
D
V
C
G
E
Y
V
A
V
T
R
K
L
-
G
I
P
F
V
F
K
A
S
F
D
K
A
N
R
S
S
I
H
S
Y
R
G
V
G
L
D
E
G
L
K
I
F
A
E
V
K
A
R
F
G
V
P
V
I
T
D
V
H
E
A
E
Q
A
A
P
V
A
E
I
A
D
V
L
Q
V
P
A
F
L
A
R
Q
T
D
L
V
V
A
I
A
K
A
G
K
P
V
N
V
K
K
P
Q
F
M
S
P
T
Q
L
K
H
V
V
S
K
C
G
E
V
-------------
G
N
D
R
V
M
L
C
E
R
G
S
S
F
G
Y
D
N
L
V
V
D
M
L
G
F
R
Q
M
A
-
E
---
T
--
T
GG
C
P
V
I
F
D
V
T
H
S
L
Q
C
R
D
P
L
G
D
A
S
G
G
R
R
R
Q
V
L
D
L
A
R
A
G
I
A
-
V
G
I
A
G
L
F
L
E
A
H
P
D
P
D
R
A
R
C
D
G
P
S
A
L
P
L
H
Q
L
E
G
L
L
S
Q
M
K
A
I
D
D
L
V
K
R
M
P
A
L
E
---
58
PsiBlast_CBE
82.08
58%
-99
- C2 -
-
3TMQ
2
?
B:
[13-283]
--------------
V
T
A
G
N
S
L
P
F
V
L
F
G
G
I
N
V
L
E
S
L
D
F
T
L
D
V
C
G
E
Y
V
A
V
T
R
K
L
-
G
I
P
F
V
F
K
A
S
F
D
K
A
N
R
S
S
I
H
S
Y
R
G
V
G
L
D
E
G
L
K
I
F
A
E
V
K
A
R
F
G
V
P
V
I
T
D
V
H
E
A
E
Q
A
A
P
V
A
E
I
A
D
V
L
Q
V
P
A
F
L
A
R
Q
T
D
L
V
V
A
I
A
K
A
G
K
P
V
N
V
K
K
P
Q
F
M
S
P
T
Q
L
K
H
V
V
S
K
C
G
E
V
-------------
G
N
D
R
V
M
L
C
E
R
G
S
S
F
G
Y
D
N
L
V
V
D
M
L
G
F
R
Q
M
A
-
E
---
T
--
T
GG
C
P
V
I
F
D
V
T
H
S
L
Q
C
R
D
P
---------
R
Q
V
L
D
L
A
R
A
G
I
A
-
V
G
I
A
G
L
F
L
E
A
H
P
D
P
D
R
A
R
C
---
S
A
L
P
L
H
Q
L
E
G
L
L
S
Q
M
K
A
I
D
D
L
V
K
R
M
P
A
L
E
---
53
PsiBlast_CBE
82.00
58%
-77
- C2 -
-
3UND
5
?
D:
[13-283]
--------------
V
T
A
G
N
S
L
P
F
V
L
F
G
G
I
N
V
L
E
S
L
D
F
T
L
D
V
C
G
E
Y
V
A
V
T
R
K
L
-
G
I
P
F
V
F
K
A
S
F
D
K
A
N
R
S
S
I
H
S
Y
R
G
V
G
L
D
E
G
L
K
I
F
A
E
V
K
A
R
F
G
V
P
V
I
T
D
V
H
E
A
E
Q
A
A
P
V
A
E
I
A
D
V
L
Q
V
P
A
F
L
A
R
Q
T
D
L
V
V
A
I
A
K
A
G
K
P
V
N
V
K
K
P
Q
F
M
S
P
T
Q
L
K
H
V
V
S
K
C
G
E
V
-------------
G
N
D
R
V
M
L
C
E
R
G
S
S
F
G
Y
D
N
L
V
V
D
M
L
G
F
R
Q
M
A
-
E
---
T
--
T
GG
C
P
V
I
F
D
V
T
H
S
L
Q
C
R
D
P
L
G
D
A
S
G
G
R
R
R
Q
V
L
D
L
A
R
A
G
I
A
-
V
G
I
A
G
L
F
L
E
A
H
P
D
P
D
R
A
R
C
D
G
P
S
A
L
P
L
H
Q
L
E
G
L
L
S
Q
M
K
A
I
D
D
L
V
K
R
M
P
A
L
E
---
164
Fugue
70.78
67%
7
- C2 -
-
1G7V
1
KDSA_ECOLI
A:
[1-284]
----
M
K
Q
K
V
V
S
I
G
D
I
N
V
A
N
D
L
P
F
V
L
F
G
G
M
N
V
L
E
S
R
D
L
A
M
R
I
C
E
H
Y
V
T
V
T
Q
K
L
G-
I
P
Y
V
F
K
A
S
F
D
K
A
N
R
S
S
I
H
S
Y
R
G
P
G
L
E
E
G
M
K
I
F
Q
E
L
K
Q
T
F
G
V
K
I
I
T
D
V
H
E
P
S
Q
A
Q
P
V
A
D
V
V
D
V
I
Q
L
P
A
F
L
A
R
Q
T
D
L
V
E
A
M
A
K
T
G
A
V
I
N
V
K
K
P
Q
F
V
S
P
G
Q
M
G
N
I
V
D
K
F
K
E
G
-------------
G
N
E
K
V
I
L
C
D
R
G
A
N
F
G
Y
D
N
L
V
V
D
M
L
G
F
S
I
M
K
-
K
V
S
G---
N
--
S
P
V
I
F
D
V
T
H
A
L
Q
C
R
D
P
F
G
A
A
S
G
G
R
R
A
Q
V
A
E
L
A
R
A
G
M
A
V
-
G
L
A
G
L
F
I
E
A
H
P
D
P
E
H
A
K
C
D
G
P
S
A
L
P
L
A
K
L
E
P
F
L
K
Q
M
K
A
I
D
D
L
V
K
G
F
E
E
L
D
T
S
K
187
HHSearch
68.94
46%
-64
* C2 *
-
4Z1D
1
KDSA_HELPY
B:
[10-275]
---------------------
K
S
V
L
I
A
G
P
C
V
I
E
S
L
E
N
L
R
S
I
A
T
K
L
Q
P
L
A
N
N
E
-
R
L
D
F
Y
F
K
A
S
F
D
K
A
N
R
T
S
L
E
S
Y
R
G
P
G
L
E
K
G
L
E
M
L
Q
T
I
K
E
E
F
G
Y
K
I
L
T
D
V
H
E
S
Y
Q
A
S
V
A
A
K
V
A
D
I
L
Q
I
P
A
F
L
C
R
Q
T
D
L
I
V
E
V
S
Q
T
N
A
I
V
N
I
K
K
G
Q
F
M
N
P
K
D
M
Q
Y
S
V
L
K
A
L
K
T
RDKSIQSPTYETA
L
K
N
G
V
W
L
C
E
R
G
S
S
F
G
Y
G
N
L
V
V
D
M
R
S
L
K
I
M
R
-
E
------
F
--
A
P
V
I
F
D
A
T
H
S
V
Q
M
P
-----------
S
F
A
P
I
L
A
R
A
A
A
A
-
V
G
I
D
G
L
F
A
E
T
H
V
D
P
K
N
A
L
S
D
G
A
N
M
L
K
P
D
E
L
E
Q
L
V
T
D
M
L
K
I
Q
N
L
-----------
179
HHSearch
67.56
47%
1
- C2 -
-
2NXG
3
KDSA_AQUAE
A:
[1-261]
--------------------
E
K
F
L
V
I
A
G
P
N
A
I
E
S
E
E
L
L
L
K
V
G
E
E
I
K
R
L
S
E
K
F
K
E
V
E
F
V
F
K
S
S
F
D
K
A
N
R
S
S
I
H
S
F
R
G
H
G
L
E
Y
G
V
K
A
L
R
K
V
K
E
E
F
G
L
K
I
T
T
D
I
H
E
S
W
Q
A
E
P
V
A
E
V
A
D
I
I
Q
I
P
A
F
L
C
R
Q
T
D
L
L
L
A
A
A
K
T
G
R
A
V
N
V
K
K
G
Q
F
L
A
P
W
D
T
K
N
V
V
E
K
L
K
F
G
-------------
G
A
K
E
I
Y
L
T
E
R
G
T
T
F
G
Y
N
N
L
V
V
D
F
R
S
L
P
I
M
K
-
Q
------
W
--
A
K
V
I
Y
D
A
T
H
S
V
Q
L
P
G
G
L
G
D
K
S
G
G
M
R
E
F
I
F
P
L
I
R
A
A
V
A
-
V
G
C
D
G
V
F
M
E
T
H
P
E
P
E
K
A
L
S
D
A
P
T
A
L
P
L
S
Q
L
E
G
I
I
E
A
I
L
E
I
R
E
V
A
S
K
Y
Y
E
-----
85
PsiBlast_CBE
67.54
49%
-8
- C2 -
-
2EF9
3
KDSA_AQUAE
A:
[4-253]
----------------------
F
L
V
I
A
G
M
N
A
I
E
S
E
E
L
L
L
K
V
G
E
E
I
K
R
L
S
E
K
F
K
E
V
E
F
V
F
K
S
S
F
D
K
A
N
R
S
S
I
H
S
F
R
G
H
G
L
E
Y
G
V
K
A
L
R
K
V
K
E
E
F
G
L
K
I
T
T
D
I
H
E
S
W
Q
A
E
P
V
A
E
V
A
D
I
I
Q
I
P
A
F
L
C
R
Q
T
D
L
L
L
A
A
A
K
T
G
R
A
V
N
V
K
K
G
Q
F
L
A
P
W
D
T
K
N
V
V
E
K
L
K
F
G
-------------
G
A
K
E
I
Y
L
T
E
R
G
T
T
F
G
Y
N
N
L
V
V
D
F
R
S
L
P
I
M
K
-
Q
---
W
-----
A
K
V
I
Y
D
A
T
H
S
V
Q
L
P
G
G
L
G
D
K
S
G
G
M
R
E
F
I
F
P
L
I
R
A
A
V
A
-
V
G
C
D
G
V
F
M
E
T
H
P
E
P
E
K
A
L
S
D
A
P
T
A
L
P
L
S
Q
L
E
G
I
I
E
A
I
L
E
I
--------------
84
PsiBlast_CBE
67.38
49%
-4
- C2 -
-
2EF9
3
KDSA_AQUAE
B:
[4-253]
----------------------
F
L
V
I
A
G
M
N
A
I
E
S
E
E
L
L
L
K
V
G
E
E
I
K
R
L
S
E
K
F
K
E
V
E
F
V
F
K
S
S
F
D
K
A
N
R
S
S
I
H
S
F
R
G
H
G
L
E
Y
G
V
K
A
L
R
K
V
K
E
E
F
G
L
K
I
T
T
D
I
H
E
S
W
Q
A
E
P
V
A
E
V
A
D
I
I
Q
I
P
A
F
L
C
R
Q
T
D
L
L
L
A
A
A
K
T
G
R
A
V
N
V
K
K
G
Q
F
L
A
P
W
D
T
K
N
V
V
E
K
L
K
F
G
-------------
G
A
K
E
I
Y
L
T
E
R
G
T
T
F
G
Y
N
N
L
V
V
D
F
R
S
L
P
I
M
K
-
Q
---
W
-----
A
K
V
I
Y
D
A
T
H
S
V
Q
L
P
G
G
L
G
D
K
S
G
G
M
R
E
F
I
F
P
L
I
R
A
A
V
A
-
V
G
C
D
G
V
F
M
E
T
H
P
E
P
E
K
A
L
S
D
A
P
T
A
L
P
L
S
Q
L
E
G
I
I
E
A
I
L
E
I
--------------
115
PsiBlast_CBE
66.80
49%
-2
- C2 -
-
2NXG
3
KDSA_AQUAE
A:
[3-252]
----------------------
F
L
V
I
A
G
P
N
A
I
E
S
E
E
L
L
L
K
V
G
E
E
I
K
R
L
S
E
K
F
K
E
V
E
F
V
F
K
S
S
F
D
K
A
N
R
S
S
I
H
S
F
R
G
H
G
L
E
Y
G
V
K
A
L
R
K
V
K
E
E
F
G
L
K
I
T
T
D
I
H
E
S
W
Q
A
E
P
V
A
E
V
A
D
I
I
Q
I
P
A
F
L
C
R
Q
T
D
L
L
L
A
A
A
K
T
G
R
A
V
N
V
K
K
G
Q
F
L
A
P
W
D
T
K
N
V
V
E
K
L
K
F
G
-------------
G
A
K
E
I
Y
L
T
E
R
G
T
T
F
G
Y
N
N
L
V
V
D
F
R
S
L
P
I
M
K
-
Q
---
W
-----
A
K
V
I
Y
D
A
T
H
S
V
Q
L
P
G
G
L
G
D
K
S
G
G
M
R
E
F
I
F
P
L
I
R
A
A
V
A
-
V
G
C
D
G
V
F
M
E
T
H
P
E
P
E
K
A
L
S
D
A
P
T
A
L
P
L
S
Q
L
E
G
I
I
E
A
I
L
E
I
--------------
153
PsiBlast_CBE
66.64
47%
-7
- C2 -
-
1FY6
1
KDSA_AQUAE
A:
[4-253]
----------------------
F
L
V
I
A
G
P
C
A
I
E
S
E
E
L
L
L
K
V
G
E
E
I
K
R
L
S
E
K
F
K
E
V
E
F
V
F
K
S
S
F
D
K
A
N
R
S
S
I
H
S
F
R
G
H
G
L
E
Y
G
V
K
A
L
R
K
V
K
E
E
F
G
L
K
I
T
T
D
I
H
E
S
W
Q
A
E
P
V
A
E
V
A
D
I
I
Q
I
P
A
F
L
C
R
Q
T
D
L
L
L
A
A
A
K
T
G
R
A
V
N
V
K
K
G
Q
F
L
A
P
W
D
T
K
N
V
V
E
K
L
K
F
G
-------------
G
A
K
E
I
Y
L
T
E
R
G
T
T
F
G
Y
N
N
L
V
V
D
F
R
S
L
P
I
M
K
-
Q
---
W
-----
A
K
V
I
Y
D
A
T
H
S
V
Q
L
P
G
G
L
G
-----
M
R
E
F
I
F
P
L
I
R
A
A
V
A
-
V
G
C
D
G
V
F
M
E
T
H
P
E
P
E
K
A
L
S
D
A
S
T
Q
L
P
L
S
Q
L
E
G
I
I
E
A
I
L
E
I
--------------
155
PsiBlast_CBE
66.55
47%
-5
- C2 -
-
1FXQ
3
KDSA_AQUAE
A:
[4-253]
----------------------
F
L
V
I
A
G
P
C
A
I
E
S
E
E
L
L
L
K
V
G
E
E
I
K
R
L
S
E
K
F
K
E
V
E
F
V
F
K
S
S
F
D
K
A
N
R
S
S
I
H
S
F
R
G
H
G
L
E
Y
G
V
K
A
L
R
K
V
K
E
E
F
G
L
K
I
T
T
D
I
H
E
S
W
Q
A
E
P
V
A
E
V
A
D
I
I
Q
I
P
A
F
L
C
R
Q
T
D
L
L
L
A
A
A
K
T
G
R
A
V
N
V
K
K
G
Q
F
L
A
P
W
D
T
K
N
V
V
E
K
L
K
F
G
-------------
G
A
K
E
I
Y
L
T
E
R
G
T
T
F
G
Y
N
N
L
V
V
D
F
R
S
L
P
I
M
K
-
Q
---
W
-----
A
K
V
I
Y
D
A
T
H
S
V
Q
L
P
G
G
L
G
D
K
S
G
G
M
R
E
F
I
F
P
L
I
R
A
A
V
A
-
V
G
C
D
G
V
F
M
E
T
H
P
E
P
E
K
A
L
S
D
A
S
T
Q
L
P
L
S
Q
L
E
G
I
I
E
A
I
L
E
I
--------------
162
PsiBlast_CBE
66.53
47%
-5
- C2 -
-
1FWT
2
KDSA_AQUAE
A:
[4-253]
----------------------
F
L
V
I
A
G
P
C
A
I
E
S
E
E
L
L
L
K
V
G
E
E
I
K
R
L
S
E
K
F
K
E
V
E
F
V
F
K
S
S
F
D
K
A
N
R
S
S
I
H
S
F
R
G
H
G
L
E
Y
G
V
K
A
L
R
K
V
K
E
E
F
G
L
K
I
T
T
D
I
H
E
S
W
Q
A
E
P
V
A
E
V
A
D
I
I
Q
I
P
A
F
L
C
R
Q
T
D
L
L
L
A
A
A
K
T
G
R
A
V
N
V
K
K
G
Q
F
L
A
P
W
D
T
K
N
V
V
E
K
L
K
F
G
-------------
G
A
K
E
I
Y
L
T
E
R
G
T
T
F
G
Y
N
N
L
V
V
D
F
R
S
L
P
I
M
K
-
Q
---
W
-----
A
K
V
I
Y
D
A
T
H
S
V
Q
L
P
G
G
L
G
D
K
S
G
G
M
R
E
F
I
F
P
L
I
R
A
A
V
A
-
V
G
C
D
G
V
F
M
E
T
H
P
E
P
E
K
A
L
S
D
A
S
T
Q
L
P
L
S
Q
L
E
G
I
I
E
A
I
L
E
I
--------------
145
PsiBlast_CBE
66.37
47%
-8
- C2 -
-
1PCW
2
KDSA_AQUAE
A:
[4-253]
----------------------
F
L
V
I
A
G
P
C
A
I
E
S
E
E
L
L
L
K
V
G
E
E
I
K
R
L
S
E
K
F
K
E
V
E
F
V
F
K
S
S
F
D
K
A
N
R
S
S
I
H
S
F
R
G
H
G
L
E
Y
G
V
K
A
L
R
K
V
K
E
E
F
G
L
K
I
T
T
D
I
H
E
S
W
Q
A
E
P
V
A
E
V
A
D
I
I
Q
I
P
A
F
L
C
R
Q
T
D
L
L
L
A
A
A
K
T
G
R
A
V
N
V
K
K
G
Q
F
L
A
P
W
D
T
K
N
V
V
E
K
L
K
F
G
-------------
G
A
K
E
I
Y
L
T
E
R
G
T
T
F
G
Y
N
N
L
V
V
D
F
R
S
L
P
I
M
K
-
Q
---
W
-----
A
K
V
I
Y
D
A
T
H
S
V
Q
L
P
G
------
G
G
M
R
E
F
I
F
P
L
I
R
A
A
V
A
-
V
G
C
D
G
V
F
M
E
T
H
P
E
P
E
K
A
L
S
D
A
S
T
Q
L
P
L
S
Q
L
E
G
I
I
E
A
I
L
E
I
--------------
133
PsiBlast_CBE
66.24
48%
-6
- C2 -
-
2NWR
1
KDSA_AQUAE
A:
[4-253]
----------------------
F
L
V
I
A
G
P
N
A
I
E
S
E
E
L
L
L
K
V
G
E
E
I
K
R
L
S
E
K
F
K
E
V
E
F
V
F
K
S
S
F
D
K
A
N
R
S
S
I
H
S
F
R
G
H
G
L
E
Y
G
V
K
A
L
R
K
V
K
E
E
F
G
L
K
I
T
T
D
I
H
E
S
W
Q
A
E
P
V
A
E
V
A
D
I
I
Q
I
P
A
F
L
C
R
Q
T
D
L
L
L
A
A
A
K
T
G
R
A
V
N
V
K
K
G
Q
F
L
A
P
W
D
T
K
N
V
V
E
K
L
K
F
G
-------------
G
A
K
E
I
Y
L
T
E
R
G
T
T
F
G
Y
N
N
L
V
V
D
F
R
S
L
P
I
M
K
-
Q
---
W
-----
A
K
V
I
Y
D
A
T
H
S
V
Q
L
P
G
------
G
G
M
R
E
F
I
F
P
L
I
R
A
A
V
A
-
V
G
C
D
G
V
F
M
E
T
H
P
E
P
E
K
A
L
S
D
A
S
T
Q
L
P
L
S
Q
L
E
G
I
I
E
A
I
L
E
I
--------------
140
PsiBlast_CBE
66.21
47%
-9
- C2 -
-
2A21
1
KDSA_AQUAE
B:
[4-253]
----------------------
F
L
V
I
A
G
P
C
A
I
E
S
E
E
L
L
L
K
V
G
E
E
I
K
R
L
S
E
K
F
K
E
V
E
F
V
F
K
S
S
F
D
K
A
N
R
S
S
I
H
S
F
R
G
H
G
L
E
Y
G
V
K
A
L
R
K
V
K
E
E
F
G
L
K
I
T
T
D
I
H
E
S
W
Q
A
E
P
V
A
E
V
A
D
I
I
Q
I
P
A
F
L
C
R
Q
T
D
L
L
L
A
A
A
K
T
G
R
A
V
N
V
K
K
G
Q
F
L
A
P
W
D
T
K
N
V
V
E
K
L
K
F
G
-------------
G
A
K
E
I
Y
L
T
E
R
G
T
T
F
G
Y
N
N
L
V
V
D
F
R
S
L
P
I
M
K
-
Q
---
W
-----
A
K
V
I
Y
D
A
T
H
S
V
Q
L
P
G
-------
G
M
R
E
F
I
F
P
L
I
R
A
A
V
A
-
V
G
C
D
G
V
F
M
E
T
H
P
E
P
E
K
A
L
S
D
A
S
T
Q
L
P
L
S
Q
L
E
G
I
I
E
A
I
L
E
I
--------------
134
PsiBlast_CBE
66.18
47%
-6
- C2 -
-
3E12
2
KDSA_AQUAE
B:
[4-253]
----------------------
F
L
V
I
A
G
P
C
A
I
E
S
E
E
L
L
L
K
V
G
E
E
I
K
R
L
S
E
K
F
K
E
V
E
F
V
F
K
S
S
F
D
K
A
N
R
S
S
I
H
S
F
R
G
H
G
L
E
Y
G
V
K
A
L
R
K
V
K
E
E
F
G
L
K
I
T
T
D
I
H
E
S
W
Q
A
E
P
V
A
E
V
A
D
I
I
Q
I
P
A
F
L
C
R
Q
T
D
L
L
L
A
A
A
K
T
G
R
A
V
N
V
K
K
G
Q
F
L
A
P
W
D
T
K
N
V
V
E
K
L
K
F
G
-------------
G
A
K
E
I
Y
L
T
E
R
G
T
T
F
G
Y
N
N
L
V
V
D
F
R
S
L
P
I
M
K
-
Q
---
W
-----
A
K
V
I
Y
D
A
T
H
S
V
Q
L
P
G
------
G
G
M
R
E
F
I
F
P
L
I
R
A
A
V
A
-
V
G
C
D
G
V
F
M
E
T
H
P
E
P
E
K
A
L
S
D
A
S
T
Q
L
P
L
S
Q
L
E
G
I
I
E
A
I
L
E
I
--------------
148
PsiBlast_CBE
66.10
47%
-9
- C2 -
-
1JCY
2
KDSA_AQUAE
B:
[4-253]
----------------------
F
L
V
I
A
G
P
C
A
I
E
S
E
E
L
L
L
K
V
G
E
E
I
K
R
L
S
E
K
F
K
E
V
E
F
V
F
K
S
S
F
D
K
A
N
R
S
S
I
H
S
F
R
G
H
G
L
E
Y
G
V
K
A
L
R
K
V
K
E
E
F
G
L
K
I
T
T
D
I
H
E
S
W
Q
A
E
P
V
A
E
V
A
D
I
I
Q
I
P
A
F
L
C
R
Q
T
D
L
L
L
A
A
A
K
T
G
R
A
V
N
V
K
K
G
Q
F
L
A
P
W
D
T
K
N
V
V
E
K
L
K
F
G
-------------
G
A
K
E
I
Y
L
T
E
R
G
T
T
F
G
Y
N
N
L
V
V
D
F
R
S
L
P
I
M
K
-
Q
---
W
-----
A
K
V
I
Y
D
A
T
H
S
V
Q
L
P
G
-------
G
M
R
E
F
I
F
P
L
I
R
A
A
V
A
-
V
G
C
D
G
V
F
M
E
T
H
P
E
P
E
K
A
L
S
D
A
S
T
Q
L
P
L
S
Q
L
E
G
I
I
E
A
I
L
E
I
--------------
129
PsiBlast_CBE
65.97
48%
-6
- C2 -
-
2NX1
3
KDSA_AQUAE
A:
[4-253]
----------------------
F
L
V
I
A
G
P
N
A
I
E
S
E
E
L
L
L
K
V
G
E
E
I
K
R
L
S
E
K
F
K
E
V
E
F
V
F
K
S
S
F
D
K
A
N
R
S
S
I
H
S
F
R
G
H
G
L
E
Y
G
V
K
A
L
R
K
V
K
E
E
F
G
L
K
I
T
T
D
I
H
E
S
W
Q
A
E
P
V
A
E
V
A
D
I
I
Q
I
P
A
F
L
C
R
Q
T
D
L
L
L
A
A
A
K
T
G
R
A
V
N
V
K
K
G
Q
F
L
A
P
W
D
T
K
N
V
V
E
K
L
K
F
G
-------------
G
A
K
E
I
Y
L
T
E
R
G
T
T
F
G
Y
N
N
L
V
V
D
F
R
S
L
P
I
M
K
-
Q
---
W
-----
A
K
V
I
Y
D
A
T
H
S
V
Q
L
P
G
G
L
G
D
K
S
G
G
M
R
E
F
I
F
P
L
I
R
A
A
V
A
-
V
G
C
D
G
V
F
M
E
T
H
P
E
P
E
K
A
L
S
D
A
S
T
Q
L
P
L
S
Q
L
E
G
I
I
E
A
I
L
E
I
--------------
143
PsiBlast_CBE
65.93
47%
-7
- C2 -
-
1PE1
1
KDSA_AQUAE
A:
[4-253]
----------------------
F
L
V
I
A
G
P
C
A
I
E
S
E
E
L
L
L
K
V
G
E
E
I
K
R
L
S
E
K
F
K
E
V
E
F
V
F
K
S
S
F
D
K
A
N
R
S
S
I
H
S
F
R
G
H
G
L
E
Y
G
V
K
A
L
R
K
V
K
E
E
F
G
L
K
I
T
T
D
I
H
E
S
W
Q
A
E
P
V
A
E
V
A
D
I
I
Q
I
P
A
F
L
C
R
Q
T
D
L
L
L
A
A
A
K
T
G
R
A
V
N
V
K
K
G
Q
F
L
A
P
W
D
T
K
N
V
V
E
K
L
K
F
G
-------------
G
A
K
E
I
Y
L
T
E
R
G
T
T
F
G
Y
N
N
L
V
V
D
F
R
S
L
P
I
M
K
-
Q
---
W
-----
A
K
V
I
Y
D
A
T
H
S
V
Q
L
P
G
------
G
G
M
R
E
F
I
F
P
L
I
R
A
A
V
A
-
V
G
C
D
G
V
F
M
E
T
H
P
E
P
E
K
A
L
S
D
A
S
T
Q
L
P
L
S
Q
L
E
G
I
I
E
A
I
L
E
I
--------------
114
PsiBlast_CBE
65.93
49%
-6
- C2 -
-
2NXG
2
KDSA_AQUAE
B:
[3-252]
----------------------
F
L
V
I
A
G
P
N
A
I
E
S
E
E
L
L
L
K
V
G
E
E
I
K
R
L
S
E
K
F
K
E
V
E
F
V
F
K
S
S
F
D
K
A
N
R
S
S
I
H
S
F
R
G
H
G
L
E
Y
G
V
K
A
L
R
K
V
K
E
E
F
G
L
K
I
T
T
D
I
H
E
S
W
Q
A
E
P
V
A
E
V
A
D
I
I
Q
I
P
A
F
L
C
R
Q
T
D
L
L
L
A
A
A
K
T
G
R
A
V
N
V
K
K
G
Q
F
L
A
P
W
D
T
K
N
V
V
E
K
L
K
F
G
-------------
G
A
K
E
I
Y
L
T
E
R
G
T
T
F
G
Y
N
N
L
V
V
D
F
R
S
L
P
I
M
K
-
Q
---
W
-----
A
K
V
I
Y
D
A
T
H
S
V
Q
L
P
G
-------
G
M
R
E
F
I
F
P
L
I
R
A
A
V
A
-
V
G
C
D
G
V
F
M
E
T
H
P
E
P
E
K
A
L
S
D
A
P
T
A
L
P
L
S
Q
L
E
G
I
I
E
A
I
L
E
I
--------------
160
PsiBlast_CBE
65.82
47%
-6
- C2 -
-
1FWW
2
KDSA_AQUAE
A:
[4-253]
----------------------
F
L
V
I
A
G
P
C
A
I
E
S
E
E
L
L
L
K
V
G
E
E
I
K
R
L
S
E
K
F
K
E
V
E
F
V
F
K
S
S
F
D
K
A
N
R
S
S
I
H
S
F
R
G
H
G
L
E
Y
G
V
K
A
L
R
K
V
K
E
E
F
G
L
K
I
T
T
D
I
H
E
S
W
Q
A
E
P
V
A
E
V
A
D
I
I
Q
I
P
A
F
L
C
R
Q
T
D
L
L
L
A
A
A
K
T
G
R
A
V
N
V
K
K
G
Q
F
L
A
P
W
D
T
K
N
V
V
E
K
L
K
F
G
-------------
G
A
K
E
I
Y
L
T
E
R
G
T
T
F
G
Y
N
N
L
V
V
D
F
R
S
L
P
I
M
K
-
Q
---
W
-----
A
K
V
I
Y
D
A
T
H
S
V
Q
L
P
G
G
L
G
D
K
S
G
G
M
R
E
F
I
F
P
L
I
R
A
A
V
A
-
V
G
C
D
G
V
F
M
E
T
H
P
E
P
E
K
A
L
S
D
A
S
T
Q
L
P
L
S
Q
L
E
G
I
I
E
A
I
L
E
I
--------------
131
PsiBlast_CBE
65.82
48%
-1
- C2 -
-
2NWS
3
KDSA_AQUAE
A:
[4-253]
----------------------
F
L
V
I
A
G
P
N
A
I
E
S
E
E
L
L
L
K
V
G
E
E
I
K
R
L
S
E
K
F
K
E
V
E
F
V
F
K
S
S
F
D
K
A
N
R
S
S
I
H
S
F
R
G
H
G
L
E
Y
G
V
K
A
L
R
K
V
K
E
E
F
G
L
K
I
T
T
D
I
H
E
S
W
Q
A
E
P
V
A
E
V
A
D
I
I
Q
I
P
A
F
L
C
R
Q
T
D
L
L
L
A
A
A
K
T
G
R
A
V
N
V
K
K
G
Q
F
L
A
P
W
D
T
K
N
V
V
E
K
L
K
F
G
-------------
G
A
K
E
I
Y
L
T
E
R
G
T
T
F
G
Y
N
N
L
V
V
D
F
R
S
L
P
I
M
K
-
Q
---
W
-----
A
K
V
I
Y
D
A
T
H
S
V
Q
L
P
G
G
L
G
D
K
S
G
G
M
R
E
F
I
F
P
L
I
R
A
A
V
A
-
V
G
C
D
G
V
F
M
E
T
H
P
E
P
E
K
A
L
S
D
A
S
T
Q
L
P
L
S
Q
L
E
G
I
I
E
A
I
L
E
I
--------------
141
PsiBlast_CBE
65.60
47%
-6
- C2 -
-
2A21
1
KDSA_AQUAE
A:
[4-253]
----------------------
F
L
V
I
A
G
P
C
A
I
E
S
E
E
L
L
L
K
V
G
E
E
I
K
R
L
S
E
K
F
K
E
V
E
F
V
F
K
S
S
F
D
K
A
N
R
S
S
I
H
S
F
R
G
H
G
L
E
Y
G
V
K
A
L
R
K
V
K
E
E
F
G
L
K
I
T
T
D
I
H
E
S
W
Q
A
E
P
V
A
E
V
A
D
I
I
Q
I
P
A
F
L
C
R
Q
T
D
L
L
L
A
A
A
K
T
G
R
A
V
N
V
K
K
G
Q
F
L
A
P
W
D
T
K
N
V
V
E
K
L
K
F
G
-------------
G
A
K
E
I
Y
L
T
E
R
G
T
T
F
G
Y
N
N
L
V
V
D
F
R
S
L
P
I
M
K
-
Q
---
W
-----
A
K
V
I
Y
D
A
T
H
S
V
Q
L
P
G
G
L
G
D
K
S
G
G
M
R
E
F
I
F
P
L
I
R
A
A
V
A
-
V
G
C
D
G
V
F
M
E
T
H
P
E
P
E
K
A
L
S
D
A
S
T
Q
L
P
L
S
Q
L
E
G
I
I
E
A
I
L
E
I
--------------
135
PsiBlast_CBE
65.60
47%
-5
- C2 -
-
3E12
2
KDSA_AQUAE
A:
[4-253]
----------------------
F
L
V
I
A
G
P
C
A
I
E
S
E
E
L
L
L
K
V
G
E
E
I
K
R
L
S
E
K
F
K
E
V
E
F
V
F
K
S
S
F
D
K
A
N
R
S
S
I
H
S
F
R
G
H
G
L
E
Y
G
V
K
A
L
R
K
V
K
E
E
F
G
L
K
I
T
T
D
I
H
E
S
W
Q
A
E
P
V
A
E
V
A
D
I
I
Q
I
P
A
F
L
C
R
Q
T
D
L
L
L
A
A
A
K
T
G
R
A
V
N
V
K
K
G
Q
F
L
A
P
W
D
T
K
N
V
V
E
K
L
K
F
G
-------------
G
A
K
E
I
Y
L
T
E
R
G
T
T
F
G
Y
N
N
L
V
V
D
F
R
S
L
P
I
M
K
-
Q
---------
A
K
V
I
Y
D
A
T
H
S
V
Q
L
P
G
G
-----
G
G
M
R
E
F
I
F
P
L
I
R
A
A
V
A
-
V
G
C
D
G
V
F
M
E
T
H
P
E
P
E
K
A
L
S
D
A
S
T
Q
L
P
L
S
Q
L
E
G
I
I
E
A
I
L
E
I
--------------
144
PsiBlast_CBE
65.51
47%
-9
- C2 -
-
1PCW
2
KDSA_AQUAE
B:
[4-253]
----------------------
F
L
V
I
A
G
P
C
A
I
E
S
E
E
L
L
L
K
V
G
E
E
I
K
R
L
S
E
K
F
K
E
V
E
F
V
F
K
S
S
F
D
K
A
N
R
S
S
I
H
S
F
R
G
H
G
L
E
Y
G
V
K
A
L
R
K
V
K
E
E
F
G
L
K
I
T
T
D
I
H
E
S
W
Q
A
E
P
V
A
E
V
A
D
I
I
Q
I
P
A
F
L
C
R
Q
T
D
L
L
L
A
A
A
K
T
G
R
A
V
N
V
K
K
G
Q
F
L
A
P
W
D
T
K
N
V
V
E
K
L
K
F
G
-------------
G
A
K
E
I
Y
L
T
E
R
G
T
T
F
G
Y
N
N
L
V
V
D
F
R
S
L
P
I
M
K
-
Q
---
W
-----
A
K
V
I
Y
D
A
T
H
S
V
Q
L
P
G
--------
M
R
E
F
I
F
P
L
I
R
A
A
V
A
-
V
G
C
D
G
V
F
M
E
T
H
P
E
P
E
K
A
L
S
D
A
S
T
Q
L
P
L
S
Q
L
E
G
I
I
E
A
I
L
E
I
--------------
159
PsiBlast_CBE
65.35
47%
-9
- C2 -
-
1FWW
2
KDSA_AQUAE
B:
[4-253]
----------------------
F
L
V
I
A
G
P
C
A
I
E
S
E
E
L
L
L
K
V
G
E
E
I
K
R
L
S
E
K
F
K
E
V
E
F
V
F
K
S
S
F
D
K
A
N
R
S
S
I
H
S
F
R
G
H
G
L
E
Y
G
V
K
A
L
R
K
V
K
E
E
F
G
L
K
I
T
T
D
I
H
E
S
W
Q
A
E
P
V
A
E
V
A
D
I
I
Q
I
P
A
F
L
C
R
Q
T
D
L
L
L
A
A
A
K
T
G
R
A
V
N
V
K
K
G
Q
F
L
A
P
W
D
T
K
N
V
V
E
K
L
K
F
G
-------------
G
A
K
E
I
Y
L
T
E
R
G
T
T
F
G
Y
N
N
L
V
V
D
F
R
S
L
P
I
M
K
-
Q
---
W
-----
A
K
V
I
Y
D
A
T
H
S
V
Q
L
P
G
-------
G
M
R
E
F
I
F
P
L
I
R
A
A
V
A
-
V
G
C
D
G
V
F
M
E
T
H
P
E
P
E
K
A
L
S
D
A
S
T
Q
L
P
L
S
Q
L
E
G
I
I
E
A
I
L
E
I
--------------
147
PsiBlast_CBE
65.35
47%
-8
- C2 -
-
1PCK
1
KDSA_AQUAE
A:
[4-253]
----------------------
F
L
V
I
A
G
P
C
A
I
E
S
E
E
L
L
L
K
V
G
E
E
I
K
R
L
S
E
K
F
K
E
V
E
F
V
F
K
S
S
F
D
K
A
N
R
S
S
I
H
S
F
R
G
H
G
L
E
Y
G
V
K
A
L
R
K
V
K
E
E
F
G
L
K
I
T
T
D
I
H
E
S
W
Q
A
E
P
V
A
E
V
A
D
I
I
Q
I
P
A
F
L
C
R
Q
T
D
L
L
L
A
A
A
K
T
G
R
A
V
N
V
K
K
G
Q
F
L
A
P
W
D
T
K
N
V
V
E
K
L
K
F
G
-------------
G
A
K
E
I
Y
L
T
E
R
G
T
T
F
G
Y
N
N
L
V
V
D
F
R
S
L
P
I
M
K
-
Q
---
W
-----
A
K
V
I
Y
D
A
T
H
S
V
Q
L
P
G
G
L
G
-----
M
R
E
F
I
F
P
L
I
R
A
A
V
A
-
V
G
C
D
G
V
F
M
E
T
H
P
E
P
E
K
A
L
S
D
A
S
T
Q
L
P
L
S
Q
L
E
G
I
I
E
A
I
L
E
I
--------------
154
PsiBlast_CBE
65.32
47%
-6
- C2 -
-
1FXQ
3
KDSA_AQUAE
B:
[4-253]
----------------------
F
L
V
I
A
G
P
C
A
I
E
S
E
E
L
L
L
K
V
G
E
E
I
K
R
L
S
E
K
F
K
E
V
E
F
V
F
K
S
S
F
D
K
A
N
R
S
S
I
H
S
F
R
G
H
G
L
E
Y
G
V
K
A
L
R
K
V
K
E
E
F
G
L
K
I
T
T
D
I
H
E
S
W
Q
A
E
P
V
A
E
V
A
D
I
I
Q
I
P
A
F
L
C
R
Q
T
D
L
L
L
A
A
A
K
T
G
R
A
V
N
V
K
K
G
Q
F
L
A
P
W
D
T
K
N
V
V
E
K
L
K
F
G
-------------
G
A
K
E
I
Y
L
T
E
R
G
T
T
F
G
Y
N
N
L
V
V
D
F
R
S
L
P
I
M
K
-
Q
---
W
-----
A
K
V
I
Y
D
A
T
H
S
V
Q
L
P
G
G
L
G
D
K
S
G
G
M
R
E
F
I
F
P
L
I
R
A
A
V
A
-
V
G
C
D
G
V
F
M
E
T
H
P
E
P
E
K
A
L
S
D
A
S
T
Q
L
P
L
S
Q
L
E
G
I
I
E
A
I
L
E
I
--------------
146
PsiBlast_CBE
65.26
47%
-8
- C2 -
-
1PCK
1
KDSA_AQUAE
B:
[4-253]
----------------------
F
L
V
I
A
G
P
C
A
I
E
S
E
E
L
L
L
K
V
G
E
E
I
K
R
L
S
E
K
F
K
E
V
E
F
V
F
K
S
S
F
D
K
A
N
R
S
S
I
H
S
F
R
G
H
G
L
E
Y
G
V
K
A
L
R
K
V
K
E
E
F
G
L
K
I
T
T
D
I
H
E
S
W
Q
A
E
P
V
A
E
V
A
D
I
I
Q
I
P
A
F
L
C
R
Q
T
D
L
L
L
A
A
A
K
T
G
R
A
V
N
V
K
K
G
Q
F
L
A
P
W
D
T
K
N
V
V
E
K
L
K
F
G
-------------
G
A
K
E
I
Y
L
T
E
R
G
T
T
F
G
Y
N
N
L
V
V
D
F
R
S
L
P
I
M
K
-
Q
---
W
-----
A
K
V
I
Y
D
A
T
H
S
V
Q
L
P
G
-------
G
M
R
E
F
I
F
P
L
I
R
A
A
V
A
-
V
G
C
D
G
V
F
M
E
T
H
P
E
P
E
K
A
L
S
D
A
S
T
Q
L
P
L
S
Q
L
E
G
I
I
E
A
I
L
E
I
--------------
130
PsiBlast_CBE
65.07
48%
1
- C2 -
-
2NWS
3
KDSA_AQUAE
B:
[4-253]
----------------------
F
L
V
I
A
G
P
N
A
I
E
S
E
E
L
L
L
K
V
G
E
E
I
K
R
L
S
E
K
F
K
E
V
E
F
V
F
K
S
S
F
D
K
A
N
R
S
S
I
H
S
F
R
G
H
G
L
E
Y
G
V
K
A
L
R
K
V
K
E
E
F
G
L
K
I
T
T
D
I
H
E
S
W
Q
A
E
P
V
A
E
V
A
D
I
I
Q
I
P
A
F
L
C
R
Q
T
D
L
L
L
A
A
A
K
T
G
R
A
V
N
V
K
K
G
Q
F
L
A
P
W
D
T
K
N
V
V
E
K
L
K
F
G
-------------
G
A
K
E
I
Y
L
T
E
R
G
T
T
F
G
Y
N
N
L
V
V
D
F
R
S
L
P
I
M
K
-
Q
---
W
-----
A
K
V
I
Y
D
A
T
H
S
V
Q
L
P
G
G
L
G
D
K
S
G
G
M
R
E
F
I
F
P
L
I
R
A
A
V
A
-
V
G
C
D
G
V
F
M
E
T
H
P
E
P
E
K
A
L
S
D
A
S
T
Q
L
P
L
S
Q
L
E
G
I
I
E
A
I
L
E
I
--------------
139
PsiBlast_CBE
64.97
47%
-5
- C2 -
-
2A2I
3
KDSA_AQUAE
A:
[4-253]
----------------------
F
L
V
I
A
G
P
C
A
I
E
S
E
E
L
L
L
K
V
G
E
E
I
K
R
L
S
E
K
F
K
E
V
E
F
V
F
K
S
S
F
D
K
A
N
R
S
S
I
H
S
F
R
G
H
G
L
E
Y
G
V
K
A
L
R
K
V
K
E
E
F
G
L
K
I
T
T
D
I
H
E
S
W
Q
A
E
P
V
A
E
V
A
D
I
I
Q
I
P
A
F
L
C
R
Q
T
D
L
L
L
A
A
A
K
T
G
R
A
V
N
V
K
K
G
Q
F
L
A
P
W
D
T
K
N
V
V
E
K
L
K
F
G
-------------
G
A
K
E
I
Y
L
T
E
R
G
T
T
F
G
Y
N
N
L
V
V
D
F
R
S
L
P
I
M
K
-
Q
---
W
-----
A
K
V
I
Y
D
A
T
H
S
V
Q
L
P
G
G
L
G
D
K
S
G
G
M
R
E
F
I
F
P
L
I
R
A
A
V
A
-
V
G
C
D
G
V
F
M
E
T
H
P
E
P
E
K
A
L
S
D
A
S
T
Q
L
P
L
S
Q
L
E
G
I
I
E
A
I
L
E
I
--------------
137
PsiBlast_CBE
64.93
47%
-4
- C2 -
-
3E0I
1
KDSA_AQUAE
A:
[4-253]
----------------------
F
L
V
I
A
G
P
C
A
I
E
S
E
E
L
L
L
K
V
G
E
E
I
K
R
L
S
E
K
F
K
E
V
E
F
V
F
K
S
S
F
D
K
A
N
R
S
S
I
H
S
F
R
G
H
G
L
E
Y
G
V
K
A
L
R
K
V
K
E
E
F
G
L
K
I
T
T
D
I
H
E
S
W
Q
A
E
P
V
A
E
V
A
D
I
I
Q
I
P
A
F
L
C
R
Q
T
D
L
L
L
A
A
A
K
T
G
R
A
V
N
V
K
K
G
Q
F
L
A
P
W
D
T
K
N
V
V
E
K
L
K
F
G
-------------
G
A
K
E
I
Y
L
T
E
R
G
T
T
F
G
Y
N
N
L
V
V
D
F
R
S
L
P
I
M
K
-
Q
---
W
-----
A
K
V
I
Y
D
A
T
H
S
V
Q
L
P
G
G
L
G
D
K
S
G
G
M
R
E
F
I
F
P
L
I
R
A
A
V
A
-
V
G
C
D
G
V
F
M
E
T
H
P
E
P
E
K
A
L
S
D
A
S
T
Q
L
P
L
S
Q
L
E
G
I
I
E
A
I
L
E
I
--------------
128
PsiBlast_CBE
64.91
48%
-0
- C2 -
-
2NX1
3
KDSA_AQUAE
B:
[4-253]
----------------------
F
L
V
I
A
G
P
N
A
I
E
S
E
E
L
L
L
K
V
G
E
E
I
K
R
L
S
E
K
F
K
E
V
E
F
V
F
K
S
S
F
D
K
A
N
R
S
S
I
H
S
F
R
G
H
G
L
E
Y
G
V
K
A
L
R
K
V
K
E
E
F
G
L
K
I
T
T
D
I
H
E
S
W
Q
A
E
P
V
A
E
V
A
D
I
I
Q
I
P
A
F
L
C
R
Q
T
D
L
L
L
A
A
A
K
T
G
R
A
V
N
V
K
K
G
Q
F
L
A
P
W
D
T
K
N
V
V
E
K
L
K
F
G
-------------
G
A
K
E
I
Y
L
T
E
R
G
T
T
F
G
Y
N
N
L
V
V
D
F
R
S
L
P
I
M
K
-
Q
---
W
-----
A
K
V
I
Y
D
A
T
H
S
V
Q
L
P
G
G
L
G
D
K
S
G
G
M
R
E
F
I
F
P
L
I
R
A
A
V
A
-
V
G
C
D
G
V
F
M
E
T
H
P
E
P
E
K
A
L
S
D
A
S
T
Q
L
P
L
S
Q
L
E
G
I
I
E
A
I
L
E
I
--------------
150
PsiBlast_CBE
64.87
47%
-9
- C2 -
-
1JCX
2
KDSA_AQUAE
B:
[4-253]
----------------------
F
L
V
I
A
G
P
C
A
I
E
S
E
E
L
L
L
K
V
G
E
E
I
K
R
L
S
E
K
F
K
E
V
E
F
V
F
K
S
S
F
D
K
A
N
R
S
S
I
H
S
F
R
G
H
G
L
E
Y
G
V
K
A
L
R
K
V
K
E
E
F
G
L
K
I
T
T
D
I
H
E
S
W
Q
A
E
P
V
A
E
V
A
D
I
I
Q
I
P
A
F
L
C
R
Q
T
D
L
L
L
A
A
A
K
T
G
R
A
V
N
V
K
K
G
Q
F
L
A
P
W
D
T
K
N
V
V
E
K
L
K
F
G
-------------
G
A
K
E
I
Y
L
T
E
R
G
T
T
F
G
Y
N
N
L
V
V
D
F
R
S
L
P
I
M
K
-
Q
---
W
-----
A
K
V
I
Y
D
A
T
H
S
V
Q
L
P
G
--------
M
R
E
F
I
F
P
L
I
R
A
A
V
A
-
V
G
C
D
G
V
F
M
E
T
H
P
E
P
E
K
A
L
S
D
A
S
T
Q
L
P
L
S
Q
L
E
G
I
I
E
A
I
L
E
I
--------------
136
PsiBlast_CBE
64.85
47%
-8
- C2 -
-
3E0I
1
KDSA_AQUAE
B:
[4-253]
----------------------
F
L
V
I
A
G
P
C
A
I
E
S
E
E
L
L
L
K
V
G
E
E
I
K
R
L
S
E
K
F
K
E
V
E
F
V
F
K
S
S
F
D
K
A
N
R
S
S
I
H
S
F
R
G
H
G
L
E
Y
G
V
K
A
L
R
K
V
K
E
E
F
G
L
K
I
T
T
D
I
H
E
S
W
Q
A
E
P
V
A
E
V
A
D
I
I
Q
I
P
A
F
L
C
R
Q
T
D
L
L
L
A
A
A
K
T
G
R
A
V
N
V
K
K
G
Q
F
L
A
P
W
D
T
K
N
V
V
E
K
L
K
F
G
-------------
G
A
K
E
I
Y
L
T
E
R
G
T
T
F
G
Y
N
N
L
V
V
D
F
R
S
L
P
I
M
K
-
Q
---
W
-----
A
K
V
I
Y
D
A
T
H
S
V
Q
L
P
G
-------
G
M
R
E
F
I
F
P
L
I
R
A
A
V
A
-
V
G
C
D
G
V
F
M
E
T
H
P
E
P
E
K
A
L
S
D
A
S
T
Q
L
P
L
S
Q
L
E
G
I
I
E
A
I
L
E
I
--------------
138
PsiBlast_CBE
64.83
47%
-10
- C2 -
-
2A2I
3
KDSA_AQUAE
B:
[4-253]
----------------------
F
L
V
I
A
G
P
C
A
I
E
S
E
E
L
L
L
K
V
G
E
E
I
K
R
L
S
E
K
F
K
E
V
E
F
V
F
K
S
S
F
D
K
A
N
R
S
S
I
H
S
F
R
G
H
G
L
E
Y
G
V
K
A
L
R
K
V
K
E
E
F
G
L
K
I
T
T
D
I
H
E
S
W
Q
A
E
P
V
A
E
V
A
D
I
I
Q
I
P
A
F
L
C
R
Q
T
D
L
L
L
A
A
A
K
T
G
R
A
V
N
V
K
K
G
Q
F
L
A
P
W
D
T
K
N
V
V
E
K
L
K
F
G
-------------
G
A
K
E
I
Y
L
T
E
R
G
T
T
F
G
Y
N
N
L
V
V
D
F
R
S
L
P
I
M
K
-
Q
---
W
-----
A
K
V
I
Y
D
A
T
H
S
V
Q
L
P
G
-------
G
M
R
E
F
I
F
P
L
I
R
A
A
V
A
-
V
G
C
D
G
V
F
M
E
T
H
P
E
P
E
K
A
L
S
D
A
S
T
Q
L
P
L
S
Q
L
E
G
I
I
E
A
I
L
E
I
--------------
132
PsiBlast_CBE
64.76
48%
-5
- C2 -
-
2NWR
1
KDSA_AQUAE
B:
[4-253]
----------------------
F
L
V
I
A
G
P
N
A
I
E
S
E
E
L
L
L
K
V
G
E
E
I
K
R
L
S
E
K
F
K
E
V
E
F
V
F
K
S
S
F
D
K
A
N
R
S
S
I
H
S
F
R
G
H
G
L
E
Y
G
V
K
A
L
R
K
V
K
E
E
F
G
L
K
I
T
T
D
I
H
E
S
W
Q
A
E
P
V
A
E
V
A
D
I
I
Q
I
P
A
F
L
C
R
Q
T
D
L
L
L
A
A
A
K
T
G
R
A
V
N
V
K
K
G
Q
F
L
A
P
W
D
T
K
N
V
V
E
K
L
K
F
G
-------------
G
A
K
E
I
Y
L
T
E
R
G
T
T
F
G
Y
N
N
L
V
V
D
F
R
S
L
P
I
M
K
-
Q
---
W
-----
A
K
V
I
Y
D
A
T
H
S
V
Q
L
P
G
-------
G
M
R
E
F
I
F
P
L
I
R
A
A
V
A
-
V
G
C
D
G
V
F
M
E
T
H
P
E
P
E
K
A
L
S
D
A
S
T
Q
L
P
L
S
Q
L
E
G
I
I
E
A
I
L
E
I
--------------
149
PsiBlast_CBE
64.75
47%
-4
- C2 -
-
1JCY
2
KDSA_AQUAE
A:
[4-253]
----------------------
F
L
V
I
A
G
P
C
A
I
E
S
E
E
L
L
L
K
V
G
E
E
I
K
R
L
S
E
K
F
K
E
V
E
F
V
F
K
S
S
F
D
K
A
N
R
S
S
I
H
S
F
R
G
H
G
L
E
Y
G
V
K
A
L
R
K
V
K
E
E
F
G
L
K
I
T
T
D
I
H
E
S
W
Q
A
E
P
V
A
E
V
A
D
I
I
Q
I
P
A
F
L
C
R
Q
T
D
L
L
L
A
A
A
K
T
G
R
A
V
N
V
K
K
G
Q
F
L
A
P
W
D
T
K
N
V
V
E
K
L
K
F
G
-------------
G
A
K
E
I
Y
L
T
E
R
G
T
T
F
G
Y
N
N
L
V
V
D
F
R
S
L
P
I
M
K
-
Q
---
W
-----
A
K
V
I
Y
D
A
T
H
S
V
Q
L
P
G
G
L
G
D
K
S
G
G
M
R
E
F
I
F
P
L
I
R
A
A
V
A
-
V
G
C
D
G
V
F
M
E
T
H
P
E
P
E
K
A
L
S
D
A
S
T
Q
L
P
L
S
Q
L
E
G
I
I
E
A
I
L
E
I
--------------
182
HHSearch
64.62
46%
-2
- C2 -
-
2NWR
1
KDSA_AQUAE
B:
[3-264]
---------------------
K
F
L
V
I
A
G
P
N
A
I
E
S
E
E
L
L
L
K
V
G
E
E
I
K
R
L
S
E
K
F
K
E
V
E
F
V
F
K
S
S
F
D
K
A
N
R
S
S
I
H
S
F
R
G
H
G
L
E
Y
G
V
K
A
L
R
K
V
K
E
E
F
G
L
K
I
T
T
D
I
H
E
S
W
Q
A
E
P
V
A
E
V
A
D
I
I
Q
I
P
A
F
L
C
R
Q
T
D
L
L
L
A
A
A
K
T
G
R
A
V
N
V
K
K
G
Q
F
L
A
P
W
D
T
K
N
V
V
E
K
L
K
F
G
-------------
G
A
K
E
I
Y
L
T
E
R
G
T
T
F
G
Y
N
N
L
V
V
D
F
R
S
L
P
I
M
K
-
Q
------
W
--
A
K
V
I
Y
D
A
T
H
S
V
Q
L
P
G
-------
G
M
R
E
F
I
F
P
L
I
R
A
A
V
A
-
V
G
C
D
G
V
F
M
E
T
H
P
E
P
E
K
A
L
S
D
A
S
T
Q
L
P
L
S
Q
L
E
G
I
I
E
A
I
L
E
I
R
E
V
A
S
K
Y
Y
E
T
I
---
142
PsiBlast_CBE
64.58
47%
-5
- C2 -
-
1PE1
1
KDSA_AQUAE
B:
[4-253]
----------------------
F
L
V
I
A
G
P
C
A
I
E
S
E
E
L
L
L
K
V
G
E
E
I
K
R
L
S
E
K
F
K
E
V
E
F
V
F
K
S
S
F
D
K
A
N
R
S
S
I
H
S
F
R
G
H
G
L
E
Y
G
V
K
A
L
R
K
V
K
E
E
F
G
L
K
I
T
T
D
I
H
E
S
W
Q
A
E
P
V
A
E
V
A
D
I
I
Q
I
P
A
F
L
C
R
Q
T
D
L
L
L
A
A
A
K
T
G
R
A
V
N
V
K
K
G
Q
F
L
A
P
W
D
T
K
N
V
V
E
K
L
K
F
G
-------------
G
A
K
E
I
Y
L
T
E
R
G
T
T
F
G
Y
N
N
L
V
V
D
F
R
S
L
P
I
M
K
-
Q
---
W
-----
A
K
V
I
Y
D
A
T
H
S
V
Q
L
P
G
-------
G
M
R
E
F
I
F
P
L
I
R
A
A
V
A
-
V
G
C
D
G
V
F
M
E
T
H
P
E
P
E
K
A
L
S
D
A
S
T
Q
L
P
L
S
Q
L
E
G
I
I
E
A
I
L
E
I
--------------
161
PsiBlast_CBE
64.34
47%
-7
- C2 -
-
1FWT
2
KDSA_AQUAE
B:
[4-253]
----------------------
F
L
V
I
A
G
P
C
A
I
E
S
E
E
L
L
L
K
V
G
E
E
I
K
R
L
S
E
K
F
K
E
V
E
F
V
F
K
S
S
F
D
K
A
N
R
S
S
I
H
S
F
R
G
H
G
L
E
Y
G
V
K
A
L
R
K
V
K
E
E
F
G
L
K
I
T
T
D
I
H
E
S
W
Q
A
E
P
V
A
E
V
A
D
I
I
Q
I
P
A
F
L
C
R
Q
T
D
L
L
L
A
A
A
K
T
G
R
A
V
N
V
K
K
G
Q
F
L
A
P
W
D
T
K
N
V
V
E
K
L
K
F
G
-------------
G
A
K
E
I
Y
L
T
E
R
G
T
T
F
G
Y
N
N
L
V
V
D
F
R
S
L
P
I
M
K
-
Q
---
W
-----
A
K
V
I
Y
D
A
T
H
S
V
Q
L
P
G
--------
M
R
E
F
I
F
P
L
I
R
A
A
V
A
-
V
G
C
D
G
V
F
M
E
T
H
P
E
P
E
K
A
L
S
D
A
S
T
Q
L
P
L
S
Q
L
E
G
I
I
E
A
I
L
E
I
--------------
151
PsiBlast_CBE
64.17
47%
-9
- C2 -
-
1JCX
2
KDSA_AQUAE
A:
[4-253]
----------------------
F
L
V
I
A
G
P
C
A
I
E
S
E
E
L
L
L
K
V
G
E
E
I
K
R
L
S
E
K
F
K
E
V
E
F
V
F
K
S
S
F
D
K
A
N
R
S
S
I
H
S
F
R
G
H
G
L
E
Y
G
V
K
A
L
R
K
V
K
E
E
F
G
L
K
I
T
T
D
I
H
E
S
W
Q
A
E
P
V
A
E
V
A
D
I
I
Q
I
P
A
F
L
C
R
Q
T
D
L
L
L
A
A
A
K
T
G
R
A
V
N
V
K
K
G
Q
F
L
A
P
W
D
T
K
N
V
V
E
K
L
K
F
G
-------------
G
A
K
E
I
Y
L
T
E
R
G
T
T
F
G
Y
N
N
L
V
V
D
F
R
S
L
P
I
M
K
-
Q
---
W
-----
A
K
V
I
Y
D
A
T
H
S
V
Q
L
P
G
--------
M
R
E
F
I
F
P
L
I
R
A
A
V
A
-
V
G
C
D
G
V
F
M
E
T
H
P
E
P
E
K
A
L
S
D
A
S
T
Q
L
P
L
S
Q
L
E
G
I
I
E
A
I
L
E
I
--------------