@TOME V2.3
(Mar 2018)
Ref.
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Doc.
Global output mode :
Sort entries by :
Atome Result
Tools Result
PDB occurence
Core Structure Cluster
Sequence Color type :
Secondary Structure
Hydrophobicity
Disulfide Bonds
TCoffee Identity Score
Uniprot annotation
Core Structure Cluster
Contacts with Ligands
Show alignment :
Atome selection
All alignments
Only Template with Ligand
Column output:
Score:
Atome Rank Value
Tools Score
Hide column
Alignment:
Sequence Identity (%)
Tcoffee Alignment Score
Hide column
3D Common Core:
Tito PKB Score
Verify3D Score
QMean Score
Hide column
Structural Clustering:
Cluster Num
3D-Jury Struct. Score
Hide column
Modeller Result :
Model Rank
QMean Score
Dfire Score
Dope Score
Errat Score
Verify3D Score
Modeller Score
Hide column
Complexes Modeling
Show Ligands of Templates
Complexes Affinity Score
Main Binding Site Identity
Hide column
Templates Information:
Uniprot entry
Cath class
Scop class
Smart class
Prosite class
Pfam class
EC Number
Taxonomy
Experiment Method
Hide column
Sequence & Result Tab:
PDB Template Sequence
Complexes Tab
Values color: [
Good
|
Correct
|
Middling
|
Bad
]
Sequence color :
Mutated
Helix
Strand
Conserved
Query sequence : LinJ_07_0770: (2018-03-08 )
MSSGPLRMPTPSAPSTPPPPTATQHHHTSSWRSWGTKGTGQRVAEGGGSTTTGSPNSSAAPPSVSVTVVVLAALTAATVSVAYNSYKVRSRSSRVYRSQSTTPGHSCTRHGEASDPSHTGDIAMDSVKTASPLSPSTARSDATTCCRSTSLGGCGSTAAHTVAGENPSSTAASENELDEGGQRERDVMAQSPSLALHTDTAADAGARSGNRDMRFALCSAPPLQMAHDSTAEFHDRCATPAASAAPSPPPPETPKALLSNYYDLEPYALQGLAGGAHGWKRVFGLLKPEMRRRSGRDEACAEDGGTAADGIPGRRAPGSLTRTYDGSRVTTTDSPALLRESPGAIVPVTPAAATRSPTRRASAVESMYRSSVVKSDVSVHSRVPGQPVATGKPCTARWYGDDHKLFSVAAASSTSASTLAQPLHPPRLSVSPVAGVPSPPSRFLNSFFFPVLQHLSFCVSRSVGSGPGESTTTGEATSGTAGSGVHTASTTNTFATSAALAVAQRNLQRDISTLVATTASVRLGASASSSFPGSHAHTARCSAVSSVAVSPRAGATGSCRSQQQHEGVTAAESCSSFAALHAGRSSSGGQRRKGVSVEGEEGAAQHVLGSHARFLSAEDKQQPGMRGSPRHQSSGACRQTPASSQKSDRSATWSGAGPCKQSIRESAQERRMPPHPSPRAAATAAGATADSGAVPAPPEASSTEEPNAAGTESVGEPASPPTMAHCCTIAEQLAVLTSRREQQHRYTQQLQASRRSAGLGAGAENALPSPLATPSSPAYTGAAAASTTLDVSNAELSKKASGMRSPFAWASQYYTDTASGVFYSSVLQPHHYENHVYSDVTTEVQQCRRRRQRDRVTSLGAGVTPASRAGAEDEDVGHETHTATPMATGAGAATAASTRRSMERPAAESSLTAGLQPAAARKASASAGTAILTSGVGSVAPLSHSKPTQPSNERRVDDLTVKHQDDGSASYTISLTYHDSETGTSRTVNTSALPPLRRCDAGASIPGLSSLSGGTTVRAAARTKRPTTTATLALSASGAASPAHSRSVSGGEAAHAFAVSSPPARPATATMMGKSLLHSQPHQASDAEDNDNASTTLGLAQAARTGGGRPRPAPRSSISVGGSLKYCSSPAAGATAAGSASGSPACDAAAASTTTASGKVNPFAAPLPPTEPQHGPRLRGVAGRNGEMAIGAFLGGGACGKVYECLNTETGQVLAAKQIVFDAKDRKLRTRLKQLELELEVLTLAARHHVRWIVGFFGAEKRGHSVLMYLEYCQHGSLLDYMMEGNSTDAAVWNTSSALDDATPKPSTAPADRSAGCHFDANGSPPVAAVAAWRRHTESVNEDASCLSARSPLRGLREVRESHTEAAAAPKTNSPKQQRQQQQVADGGSAAAGHAQRAEAEEAAATGHASPQVRTHREESAEGEEYPERREGDCLSTAAASVSSAASSVALSSSALDMMPLSEALHPQMPSLSIEQAQCFTKQIVEGLCFLHQHNYAHLDVKTANVLVAADDECRLADLGCAMRLQPPPPASPPPQQQGLAGMDKAVRGGANGDLDDAFSPPPYPVLVDRDAITELRGTALYMAPEMIRFESHAIGSPADVWSLGCVVMEMTTGCAPWRHIAKDKLRVLYRIGSARDELPLPPLIRAWAEEAREWLVREGLSATVDAEKQQDDVAACAMEAGGVAQAPRSRSASKKDREVSGVDRDSGVVGGDLDNAVSDTLDEPCSQRRRVDHGTYGCEATATPRSSSALTAKMPASVRTPATSTRGGTTSSSFARAASAMTAGLQLGESNPPDEERFFREQRHVMRLYVALQDFVTACVRVRPEDRSSTAELLRHPFLTLCKDDI
Atome Classification :
(20 SA)
.........10........20........30........40........50........60........70........80........90........100.......110.......120.......130.......140.......150.......160.......170.......180.......190.......200.......210.......220.......230.......240.......250.......260.......270.......280.......290.......300.......310.......320.......330.......340.......350.......360.......370.......380.......390.......400.......410.......420.......430.......440.......450.......460.......470.......480.......490.......500.......510.......520.......530.......540.......550.......560.......570.......580.......590.......600.......610.......620.......630.......640.......650.......660.......670.......680.......690.......700.......710.......720.......730.......740.......750.......760.......770.......780.......790.......800.......810.......820.......830.......840.......850.......860.......870.......880.......890.......900.......910.......920.......930.......940.......950.......960.......970.......980.......990.......1000......1010......1020......1030......1040......1050......1060......1070......1080......1090......1100......1110......1120......1130......1140......1150......1160......1170......1180......1190......1200......1210......1220--..---.---.-..1230..-....1240.....-.1250......1260----........1270.----.....1280......1290......1300......1310......1320......1330......1340......1350......1360......1370......1380....--..1390-.......1400......1410......1420......1430......1440......1450......1460----......---...1470......1480......1490......1500.....----.1510---.----.......1520......1530......1540......1550......1560......1570......1580......1590--........1600......1610......1620......1630-......1640........1650..--..----------..1660..-....1670......1680.--.....1690......1700....-..1710......1720----......1730......1740......1750......1760......1770......1780......1790......1800......1810......1820......1830......1840....
(Atome)
(Ident)
(Tito)
(Num)
(QMean)
(Ligand)
(Uniprot)
MSSGPLRMPTPSAPSTPPPPTATQHHHT
S
S
W
R
SWGTKGTGQ
R
V
AEGGGSTTTGSPNSSAAPPS
V
S
V
T
V
V
V
L
A
A
L
T
A
A
T
V
S
V
A
YN
S
Y
K
V
RSRS
S
R
V
Y
RSQSTTPGHSCTRHGEASDPSHTGDIAMDSVKTASPLSPSTARS
D
A
T
T
C
CRSTSLGGCGST
A
A
HTVAGENPSSTAASENELDEGGQ
R
E
R
D
V
MAQSP
S
L
A
L
H
TDTAADAGARSGNRD
M
R
F
A
LCSAPPLQMAHD
S
T
A
E
F
H
D
RCATPAASAAPSPPPPE
T
P
K
A
L
L
S
N
YYDL
E
P
Y
A
L
QGLAGG
A
H
G
W
K
R
V
F
G
LL
K
P
E
M
R
RRSGRDEACAEDGGTAADGIPGRRAPGSLTRTYDG
S
R
V
TTTDS
P
A
L
L
RESPG
A
I
V
PVTPAAATRSPT
R
R
A
S
A
V
E
S
M
Y
R
S
S
V
V
K
S
D
V
S
V
HSRVPGQPVATGKP
C
T
A
R
WYGDD
H
K
L
F
S
V
AAASST
S
A
S
T
L
AQPLHPPRLSVSPVAGVPS
P
P
S
R
F
L
N
S
F
F
F
P
V
L
Q
H
L
S
F
C
V
SRSVGSGPGESTTTGEATSGTAGS
G
V
H
TASTTNT
F
A
T
S
A
A
L
A
V
A
Q
R
N
L
Q
R
D
I
S
T
L
V
A
T
T
A
S
V
R
LGASASSSFPGSHAH
T
A
R
C
SAV
S
S
V
AVSPRAGATGSCR
S
Q
Q
Q
HEGV
T
A
A
E
S
C
S
S
F
A
A
L
HAGRSSSGGQRRKGVSVEGEE
G
A
A
Q
H
V
L
G
S
H
A
R
FLSAEDKQQPGMRGSPRHQSSGACRQTPASSQKSDRSATWSGA
G
P
C
K
Q
S
I
R
E
S
A
Q
ERRMPPHPSPRAAATAAGATADSGAVPAPPEASSTEEPNAAGTESVGEPASP
P
T
M
A
H
C
C
T
I
A
E
Q
L
A
V
L
T
S
R
R
E
Q
Q
H
R
Y
T
Q
Q
L
Q
A
S
R
RSAGLGAGAENALPSPLATPSSPAYTGAAA
A
S
T
T
L
DVS
N
A
E
L
S
K
K
ASGMRS
P
F
A
W
A
S
Q
YYTDTAS
G
V
F
Y
S
S
VLQPHHYEN
H
V
Y
S
D
V
T
T
E
V
Q
Q
C
R
R
R
R
Q
RDRVTSLGAGVTPASRAGAEDEDVGHETHTATPMATGAGAA
T
A
A
S
T
R
R
S
MERPAAES
S
L
TAGLQ
P
A
AARKASASAG
T
A
I
L
TSGVGSVAPLSHSKPTQPSNERRVD
D
L
T
V
K
HQDDGS
A
S
Y
T
I
S
L
T
Y
HDSETGTSRTVNTSALP
P
L
R
RCDAGASIPGLSSLSGG
T
T
V
R
A
AARTKRPT
T
T
A
T
L
A
L
SASGAASPAHSRSVSGGE
A
A
H
A
F
AVSSPPARP
A
T
A
T
M
M
G
K
S
L
L
HSQPHQASDAEDNDNAS
T
T
L
G
L
A
Q
A
A
RTGGGRPRPAPRSSISVGGS
L
K
YCSSPAAGATAAGSASGSPACDAAAASTTTASGKVNPFAAPLPPTEPQHGPRLRGVAGRNG
E
M
A
I
G
A
F
LGGG
A
C
G
K
V
Y
E
C
LNTETG
Q
V
L
A
A
K
Q
I
V
FDA--K
D
---
R
---
K
-
L
R
T
R
L
K
Q
L
-
E
L
E
L
E
V
L
T
L
A
A
R
H
-
H
V
R
W
I
V
G
FFGAEK------RGH
S
V
L
M
Y
L
E
Y
CQ----HG
S
L
L
D
Y
M
MEGNST
D
A
A
VWNTSSALDDATPKPSTAPADRSAG
C
H
FDANGSP
P
V
A
A
V
A
A
W
R
R
H
T
ESVNE
D
A
S
C
L
SAR
S
P
L
R
G
L
R
E
V
R
E
SHTEAAAAPKTN
S
P
K
Q
Q
R
Q
Q
Q
Q
VADG--GSAAA--GH
A
Q
R
A
E
A
E
E
AAATGHASPQVRTHREESAEGEEYPERREGD
C
L
S
T
A
A
A
S
V
S
S
A
A
S
S
VALSSSALDMMP-------
L
S
E
ALH---PQMPSL
S
I
E
Q
A
Q
C
F
T
K
Q
I
V
E
G
L
C
F
L
HQHN
Y
A
H
L
D
V
K
T
A
N
V
L
V
----AA--D---D----EC
R
L
ADL
G
C
A
M
RLQPPPPASPP
P
Q
Q
Q
G
L
A
G
M
D
K
A
VRGGANGDLDDAFSPPPY
P
V
L
VD
R
D
A
I
T
E
LRG
T
A
L
YMA
P
E
M
I
RFE----SHAIGSP
A
D
V
W
S
L
G
C
V
V
M
EMTTGC
A
P
W
R
H
I
A
K
D
K
L
R
V
L
Y
RIG-SARDELP--L
P
P
L
I
R
A
W
A
E
E
A
R
E
W
--
L
V
----------
R
EGLSATV-DAEKQ
Q
D
D
V
A
A
C
A
M
EAGGV--AQAPRSRSASKKDREVSGVDRDS-GVVGGD
L
D
N
A
V
S
D
T
L
D
----
E
P
C
S
Q
R
RRVDHGTYGCEATATPRSSSA
L
T
AKMPASVRTPATSTRGGTT
S
S
S
F
A
R
A
A
S
A
M
T
A
G
LQLGESNPP
D
E
E
R
F
F
R
E
Q
R
H
V
M
R
L
Y
V
A
L
Q
D
F
V
T
A
C
V
RVRPEDR
S
S
T
A
E
L
L
R
H
P
F
L
T
L
CKDDI
47
Fugue
71.93
20%
4
- C1 -
-
4AW2
5
MRCKA_RAT
A:
[1-416]
------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
S
G
E
V
R
L
R
Q
L
E
Q
F
I
L
D
G
P
A
Q
T
N
G
Q
C
F
S
V
E
T
L
L
D
I
L
I
C
L
Y
D
E
C
N
--
N
S
P
L
R
--
R
E
K
N
I
L
E
Y
L
E
W
A
K
P
F
T
S
K
V
K
Q
M
R
L
H
R
E
D
F
E
I
--
L
K
V
I
G
RG
A
F
G
E
V
A
V
V
K
L
K
N
A
D
K
V
F
A
M
K
I
L
N
K
W
E
M
L
K
R
A
E
T
A
C
F
R
E
E
R
D
V
L
V
N
G
D
S
K
W
I
T
T
L
H
Y
A
F
Q
D
D
N
N
L
Y
L
V
M
D
YYVGGD
L
L
T
L
L
S
---
K
F
E
D
R
L
P
E
E
M
A
R
F
Y
L
A
E
M
V
I
A
I
D
S
V
H
Q
L
H
Y
V
H
R
D
I
K
P
D
N
I
L
M
----
D
M
--
N
---
G
----
H
I
R
L
A
D
F
G
S
C
L
K
L
M
E
----------------
D
G
T
V
Q
S
S
V
A
------------------------
V
G
T
P
D
Y
I
S
P
E
I
L
Q
A
M
E
GG-
K
G
R
Y
G
P
E
C
D
W
W
S
L
G
V
C
M
Y
E
M
L
Y
G
E
T
P
F
Y
--
A
E
S
L
V
E
T
Y
G
K
I
M
-
N
H
K
E
R
F
Q
--
F
P
T
Q
V
T
D
V
S
E
N
A
K
D
L
--
I
R
----------
R
L
I
C
S
R
E
H
R
L
G
Q
N
G
I
E
D
F
K
K
H
P
F
F
S
G
I
D
--
W
D
N
I
R
N
C
E
A
P
Y
I
P
E
V
S
S
P
T
D
T
S
N
F
D
V
D
S
G
H
H
L
P
F
V
G
F
T
Y
T
----
S
S
C
V
L
S
D
R
S
C
L
R
----------------------------------------------------------------------------------------------------------------
44
Fugue
65.38
21%
-15
- C1 -
-
4DN5
7
M3K14_HUMAN
A:
[8-351]
------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
S
V
E
E
Y
L
V
H
A
L
Q
G
S
V
S
S
G
Q
A
H
S
L
T
S
L
A
K
T
W
A
A
R
G
S
R
S
R
E
P
S
P
K
T
E
D
N
E
G
V
L
L
T
E
K
L
K
P
V
D
Y
E
Y
R
E
E
V
H
W
A
T
H
Q
-
L
R
L
--
G
R
G
S
F
--
G
E
V
H
R
M
E
D
K
Q
T
G
-
F
Q
C
A
V
K
K
V
R
L
E
V
F
R
A
E
E
L
M
A
C
A
G
L
T
S
P
R
I
V
P
L
Y
G
A
V
R
E
G
P
W
V
N
I
F
M
E
L
--
L
E
G
G
S
-------
L
G
Q
L
V
K
---
E
Q
-
G
C
L
P
E
D
R
A
L
Y
Y
L
G
Q
A
L
E
G
L
E
Y
L
H
S
R
R
I
L
H
G
D
V
K
A
D
N
V
L
L
----
S
S
--
D
G--
S
----
H
A
A
L
C
D
F
G
H
A
V
C
L
Q
I
P
-------------------------------------------------
G
T
E
T
H
M
A
P
E
V
V
L
G
R
----
S
C
--
D
A
K
V
D
V
W
S
S
C
C
M
M
L
H
M
L
N
G
C
H
P
W
T
Q
F
--
F
R
G
P
L
C
L
K
I
A
S
E
P
P
P
V
R
E
--
I
P
P
S
C
A
P
L
T
A
Q
A
I
Q
E
--
G
L
----------
R
K
E
P
I
H
R
V
-
S
A
A
E
L
G
G
K
V
N
R
A
L
Q
Q
V
G
G
L
--
K
S
P
W
R
G
E
Y
K
E
P
R
H
P
----------------------------------------------------------------------------------------------------------------------------------------------------------
25
HHSearch
64.48
26%
-103
- C1 -
-
2WEL
7
KCC2D_HUMAN
A:
[3-213]
--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
T
D
E
Y
Q
L
F
E
E
L
G
K
G
A
F
S
V
V
R
R
C
M
K
I
P
T
G
Q
E
Y
A
A
K
I
I
N
T
K
K
--
L
S
----------
A
R
D
H
Q
K
L
-
E
R
E
A
R
I
C
R
L
---
L
-
K
H
P
N
I
V
R
L
H
D
S
I
S
------
E
E
G
F
H
Y
L
V
F
D
L
V
T
----
G
G
E
L
F
E
D
I
V
A
R
E
------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
Y
Y
S
E
A
D
A
S
H
C
I
Q
Q
I
L
E
S
V
N
H
C
H
L
N
G
I
V
H
R
D
L
K
P
E
N
L
L
L
----
A
S
--
K
SKG
A
----
A
V
K
L
A
D
F
G
L
A
I
E
V
Q
G
D
Q
-----------------------------------------
Q
A
W
F
G
F
A
G
T
P
G
Y
L
S
P
E
V
L
R
K
------
D
P
Y
G
K
P
V
D
M
W
A
C
G
V
I
L
Y
I
L
L
V
G
Y
P
P
F
W
D
E
---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
29
HHSearch
63.64
25%
-40
- C1 -
-
2Y7J
1
PHKG2_HUMAN
D:
[93-308]
--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
Y
Q
K
Y
D
P
K
D
V
I
G
R
G
V
S
S
V
V
R
R
C
V
H
R
A
T
G
H
E
F
A
V
K
I
M
E
V
-----
R
LSP
E
---
Q
-
L
E
E
V
R
E
A
T
-
R
R
E
T
H
I
L
R
Q
---
V
A
G
H
P
H
I
I
T
L
I
D
S
Y
E
------
S
S
S
F
M
F
L
V
F
D
L
M
R
----
K
G
E
L
F
D
Y
L
T
E
K
V
------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
A
L
S
E
K
E
T
R
S
I
M
R
S
L
L
E
A
V
S
F
L
H
A
N
N
I
V
H
R
D
L
K
P
E
N
I
L
L
----
D
D
--
N
---
M
----
Q
I
R
L
S
D
F
G
F
S
C
H
L
E
P
G
E
------------------------------------------
K
L
R
E
L
C
G
T
P
G
Y
L
A
P
E
I
L
K
C
S
MDET
H
P
G
Y
G
K
E
V
D
L
W
A
C
G
V
I
L
F
T
L
L
A
G
S
P
P
F
W
H
R
---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
46
Fugue
62.36
18%
44
- C1 -
-
3C4Z
1
RK_BOVIN
A:
[31-533]
-------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
R
D
---
R
---
K
-
Y
L
A
R
L
K
L
P
P
L
S
K
C
E
A
L
R
E
S
L
D
L
-
G
F
E
G
M
C
-----
L
E
------
Q
P
I
G
K
R
L
F
Q
Q
F
L
R
T
H
EQ
H
G
P
A
L
Q
L
W
K
D
I
E
D
Y
D
T
A
D
D
A
L
R
P
Q
K
A
Q
A
L
R
A
A
Y
L
E
P
Q
A
Q
L
F
C
S
F
L
D
A
E
T
V
A
R
A
R
A
G
G
L
F
Q
P
L
L
R
A
V
L
A
H
L
G
-
Q
A
P
F
Q
E
F
L
D
S
L
Y
F
L
R
F
L
Q
W
K
W
L
E
A
Q
P
M
G
E
D
W
F
L
D
F
R
V
L
G
R
G
GF
G
E
V
F
A
--
C
Q
M
K
A
T
G
K
L
Y
A
C
K
K
L
N
K
K
R
L
K
K
R
K
G
Y
Q
G
A
M
V
E
K
K
I
L
A
K
V
H
S
R
F
I
V
S
L
A
Y
A
F
E
T
K
T
D
L
C
L
V
M
T
I
M
N
G
G
D
-------
I
R
Y
H
I
Y
NVD
E
D
N
P
G
F
Q
E
P
R
A
I
F
Y
T
A
Q
I
V
S
G
L
E
H
L
H
Q
R
N
I
I
Y
R
D
L
K
P
E
N
V
L
L
----
D
D
--
D
---
G
----
N
V
R
I
S
D
L
G
L
A
V
E
L
K
A
G
Q
T
K
T
K
G
Y
A
-----------------------------------------
G
T
P
G
F
M
A
P
E
L
L
L
G
E
----
E
Y
--
D
F
S
V
D
Y
F
A
L
G
V
T
L
Y
E
M
I
A
A
R
G
P
F
R
A
R
G
E
K
V
E
N
K
E
L
K
Q
R
-
V
L
E
Q
A
V
T
--
Y
P
D
K
F
S
P
A
S
K
D
F
C
E
A
--
L
L
QKDPEKRLGF
R
D
G
S
C
D
G
L
-
R
T
H
P
L
F
R
D
I
S
W
R
Q
L
E
A
G
M
L
TP
P
F
V
P
D
S
R
T
V
Y
A
K
N
G
A
F
S
G
V
A
F
E
-------
K
A
D
T
E
F
F
Q
E
F
A
SGTC
P
I
P
W
Q
E
E
M
I
E
T
G
V
F
G
D
L
N
V
W
R
P
------------------------------------------------------------------------------------------------------
35
HHSearch
62.10
26%
-71
- C1 -
-
2X0G
-
DAPK1_HUMAN
A:
[10-220]
--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
D
D
Y
Y
D
T
G
E
E
L
G
S
G
Q
F
A
V
V
K
K
C
R
E
K
S
T
G
L
Q
Y
A
A
K
F
I
K
K
R
R
--
T
K
---
S
---
S
R
R
G
V
S
R
E
D
I
-
E
R
E
V
S
I
L
K
E
---
I
-
Q
H
P
N
V
I
T
L
H
E
V
Y
E
------
N
K
T
D
V
I
L
I
L
E
L
V
A
----
G
G
E
L
F
D
F
L
A
E
K
E
------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
S
L
T
E
E
E
A
T
E
F
L
K
Q
I
L
N
G
V
Y
Y
L
H
S
L
Q
I
A
H
F
D
L
K
P
E
N
I
M
L
----
L
D
--
R
---
N
VP
K
P
R
I
K
I
I
D
F
G
L
A
H
K
I
D
F
G
N
------------------------------------------
E
F
K
N
I
F
G
T
P
E
F
V
A
P
E
I
V
N
Y
------
E
P
L
G
L
E
A
D
M
W
S
I
G
V
I
T
Y
I
L
L
S
G
A
S
P
F
L
G
D
---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
38
HHSearch
60.57
28%
-109
- C1 -
-
5IU2
1
M3K8_HUMAN
B:
[72-267]
--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
T
Y
R
N
-
G
S
D
F
I
P
R
G
A
F
G
K
V
Y
L
A
Q
D
I
K
T
K
K
R
M
A
C
K
L
I
P
V
D
Q
-------------------
F
K
-
P
S
D
V
E
I
Q
A
C
---
F
-
R
H
E
N
I
A
E
L
Y
G
A
V
L
------
W
G
E
T
V
H
L
F
M
E
A
G
E
----
G
G
S
V
L
E
K
L
E
S
C
G
------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
P
M
R
E
F
E
I
I
W
V
T
K
H
V
L
K
G
L
D
F
L
H
S
K
K
V
I
H
H
D
I
K
P
S
N
I
V
F
----
M
S
--
T
--------
K
A
V
L
V
D
F
G
L
S
V
Q
M
T
E
D
V
-----------------------------------------
Y
F
P
K
D
L
R
G
T
E
I
Y
M
S
P
E
V
I
L
C
------
R
G
H
S
T
K
A
D
I
Y
S
L
G
A
T
L
I
H
M
Q
T
G
T
P
P
W
V
K
R
---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
27
HHSearch
60.53
25%
-43
- C1 -
-
2Y7J
1
PHKG2_HUMAN
C:
[93-308]
--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
Y
Q
K
Y
D
P
K
D
V
I
G
R
G
V
S
S
V
V
R
R
C
V
H
R
A
T
G
H
E
F
A
V
K
I
M
E
V
T
A
--
E
R
---
L
SPE
Q
-
L
E
E
V
R
E
A
T
-
R
R
E
T
H
I
L
R
Q
---
V
A
G
H
P
H
I
I
T
L
I
D
S
Y
E
------
S
S
S
F
M
F
L
V
F
D
L
M
R
----
K
G
E
L
F
D
Y
L
T
E
K
V
------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
A
L
S
E
K
E
T
R
S
I
M
R
S
L
L
E
A
V
S
F
L
H
A
N
N
I
V
H
R
D
L
K
P
E
N
I
L
L
----
D
D
--
N
---
M
----
Q
I
R
L
S
D
F
G
F
S
C
H
L
E
P
G
E
------------------------------------------
K
L
R
E
L
C
G
T
P
G
Y
L
A
P
E
I
L
K
C
S
MDET
H
P
G
Y
G
K
E
V
D
L
W
A
C
G
V
I
L
F
T
L
L
A
G
S
P
P
F
W
H
R
---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
26
HHSearch
60.15
25%
-122
* C1 *
-
3C0I
1
CSKP_HUMAN
A:
[23-235]
--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
E
D
V
Y
E
L
C
E
V
I
G
K
G
P
F
S
V
V
R
R
C
I
N
R
E
T
G
Q
Q
F
A
V
K
I
V
D
V
A
K
--
F
T
---
S
---
S
-
P
G
L
S
T
E
D
L
-
K
R
E
A
S
I
C
H
M
---
L
-
K
H
P
H
I
V
E
L
L
E
T
Y
S
------
S
D
G
M
L
Y
M
V
F
E
F
M
D
----
G
A
D
L
C
F
E
I
V
K
R
A
D
A
--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
G
F
V
Y
S
E
A
V
A
S
H
Y
M
R
Q
I
L
E
A
L
R
Y
C
H
D
N
N
I
I
H
R
D
V
K
P
H
C
V
L
L
----
A
S
--
K
---
E
NS
A
-
P
V
K
L
G
G
F
G
V
A
I
Q
L
G
E
S
G
-----------------------------------------
L
V
A
G
G
R
V
G
T
P
H
F
M
A
P
E
V
V
K
R
------
E
P
Y
G
K
P
V
D
V
W
G
C
G
V
I
L
F
I
L
L
S
G
C
L
P
F
Y
G
----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
30
HHSearch
58.88
25%
-128
- C1 -
-
3C0G
1
CSKP_HUMAN
B:
[23-235]
--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
E
D
V
Y
E
L
C
E
V
I
G
K
G
P
F
S
V
V
R
R
C
I
N
R
E
T
G
Q
Q
F
A
V
K
I
V
D
V
A
K
--
F
T
---
S
---
S
-
P
G
L
S
T
E
D
L
-
K
R
E
A
S
I
C
H
M
---
L
-
K
H
P
H
I
V
E
L
L
E
T
Y
S
------
S
D
G
M
L
Y
M
V
F
E
F
M
D
----
G
A
D
L
C
F
E
I
V
K
R
A
D
A
--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
G
F
V
Y
S
E
A
V
A
S
H
Y
M
R
Q
I
L
E
A
L
R
Y
C
H
D
N
N
I
I
H
R
D
V
K
P
H
C
V
L
L
----
A
S
--
K
---
E
NS
A
-
P
V
K
L
G
G
F
G
V
A
I
Q
L
G
E
S
G
-----------------------------------------
L
V
A
G
G
R
V
G
T
P
H
F
M
A
P
E
V
V
K
R
------
E
P
Y
G
K
P
V
D
V
W
G
C
G
V
I
L
F
I
L
L
S
G
C
L
P
F
Y
G
----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
37
HHSearch
58.76
24%
-130
- C1 -
-
4XBR
1
INKA1_HUMAN
A:
[94-293]
---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
S
Y
L
D
N
F
I
K
I
G
E
G
S
T
G
I
V
C
I
A
T
V
R
S
S
G
K
L
V
A
V
K
K
M
D
L
R
K
--
Q
------------
Q
R
R
E
L
L
-
F
N
E
V
V
I
M
R
D
---
Y
-
Q
H
E
N
V
V
E
M
Y
N
S
Y
L
------
V
G
D
E
L
W
V
V
M
E
F
L
E
----
G
G
A
L
T
D
I
V
T
H
T
-------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
R
M
N
E
E
Q
I
A
A
V
C
L
A
V
L
Q
A
L
S
V
L
H
A
Q
G
V
I
H
R
D
I
K
S
D
S
I
L
L
----
T
H
--
D
---
G
----
R
V
K
L
S
D
F
G
F
C
A
Q
V
S
K
E
V
-----------------------------------------
P
R
R
K
S
L
V
G
T
P
Y
W
M
A
P
E
L
I
S
R
------
L
P
Y
G
P
E
V
D
I
W
S
L
G
I
M
V
I
E
M
V
D
G
E
P
P
Y
F
N
E
---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
21
HHSearch
58.70
27%
-131
- C1 -
-
2X4F
4
MYLK4_HUMAN
A:
[89-291]
---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
Y
T
V
S
K
T
E
I
L
G
-----
Q
V
H
K
C
E
E
T
A
T
G
L
K
L
A
A
K
I
I
K
T
R
G
--
M
------------
K
D
K
E
E
V
-
K
N
E
I
S
V
M
N
Q
---
L
-
D
H
A
N
L
I
Q
L
Y
D
A
F
E
------
S
K
N
D
I
V
L
V
M
E
Y
V
D
----
G
G
E
L
F
D
R
I
I
D
E
S
-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
Y
N
L
T
E
L
D
T
I
L
F
M
K
Q
I
C
E
G
I
R
H
M
H
Q
M
Y
I
L
H
L
D
L
K
P
E
N
I
L
C
VN--
R
D
--
A
---
K
----
Q
I
K
I
I
D
F
G
L
A
R
R
Y
K
P
R
E
------------------------------------------
K
L
K
V
N
F
G
T
P
E
F
L
A
P
E
V
V
N
Y
------
D
F
V
S
F
P
T
D
M
W
S
V
G
V
I
A
Y
M
L
L
S
G
L
S
P
F
L
G
D
---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
40
HHSearch
57.75
27%
-40
- C1 -
-
5BYZ
7
MK07_HUMAN
A:
[5-218]
--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
G
D
E
Y
E
I
I
E
T
I
G
N
G
A
Y
G
V
V
S
S
A
R
R
R
L
T
G
Q
Q
V
A
I
K
K
I
P
N
A
F
--
D
V
----------
V
T
N
A
K
R
T
-
L
R
E
L
K
I
L
K
H
---
F
-
K
H
D
N
I
I
A
I
K
D
I
L
R
P
TVPYG
E
F
K
S
V
Y
V
V
L
D
L
M
E
----
S
-
D
L
H
Q
I
I
H
S
S
Q
------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
P
L
T
L
E
H
V
R
Y
F
L
Y
Q
L
L
R
G
L
K
Y
M
H
S
A
Q
V
I
H
R
D
L
K
P
S
N
L
L
V
----
N
E
--
N
---
C
----
E
L
K
I
G
D
F
G
M
A
R
G
L
C
T
S
P
A
E
-------------------------------------
H
Q
Y
F
M
T
E
Y
V
A
T
R
W
Y
R
A
P
E
L
M
L
S
L
-----
H
E
Y
T
Q
A
I
D
L
W
S
V
G
C
I
F
G
E
M
L
A
R
R
Q
L
F
P
G
K
---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
23
HHSearch
57.25
23%
-112
- C1 -
-
1TKI
-
TITIN_HUMAN
A:
[21-223]
--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
Y
E
K
Y
M
I
A
E
D
L
G
R
G
E
F
G
I
V
H
R
C
V
E
T
S
S
K
K
T
Y
M
A
K
F
V
K
V
K
G
---------------
T
D
Q
V
L
V
-
K
K
E
I
S
I
L
N
I
---
A
-
R
H
R
N
I
L
H
L
H
E
S
F
E
------
S
M
E
E
L
V
M
I
F
E
F
I
S
----
G
L
D
I
F
E
R
I
N
T
S
A
-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
F
E
L
N
E
R
E
I
V
S
Y
V
H
Q
V
C
E
A
L
Q
F
L
H
S
H
N
I
G
H
F
D
I
R
P
E
N
I
I
Y
----
Q
T
RR
S
---
S
----
T
I
K
I
I
E
F
G
Q
A
R
Q
L
K
P
G
D
------------------------------------------
N
F
R
L
L
F
T
A
P
E
Y
Y
A
P
E
V
H
Q
H
------
D
V
V
S
T
A
T
D
M
W
S
L
G
T
L
V
Y
V
L
L
S
G
I
N
P
F
L
A
E
---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
34
HHSearch
55.86
24%
-128
- C1 -
-
4BGQ
2
CDKL5_HUMAN
A:
[11-215]
--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
M
N
K
F
E
I
L
G
V
V
G
E
G
A
Y
G
V
V
L
K
C
R
H
K
E
T
H
E
I
V
A
I
K
K
F
K
-------------------
V
K
E
T
T
-
L
R
E
L
K
M
L
R
T
---
L
-
K
Q
E
N
I
V
E
L
K
E
A
F
R
------
R
R
G
K
L
Y
L
V
F
E
Y
V
E
----
K
N
M
L
E
L
L
E
E
M
P
N
------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
G
V
P
P
E
K
V
K
S
Y
I
Y
Q
L
I
K
A
I
H
W
C
H
K
N
D
I
V
H
R
D
I
K
P
E
N
L
L
I
----
S
H
--
N
---
D
----
V
L
K
L
C
D
F
G
F
A
R
N
L
S
E
---------------------------------------------------
T
R
W
Y
R
S
P
E
L
L
L
G
------
A
P
Y
G
K
S
V
D
M
W
S
V
G
C
I
L
G
E
L
S
D
G
Q
P
L
F
P
G
E
---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
33
HHSearch
53.07
25%
-117
- C1 -
-
5J5T
1
M4K3_HUMAN
A:
[2-209]
-------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
S
Q
E
D
F
E
L
I
Q
R
I
G
S
G
T
Y
G
D
V
Y
K
A
R
N
V
N
T
G
E
L
A
A
I
K
V
I
K
L
E
P
--
G
------------
E
D
F
A
V
V
-
Q
Q
E
I
I
M
M
K
D
---
C
-
K
H
P
N
I
V
A
Y
F
G
S
Y
L
------
R
R
D
K
L
W
I
C
M
E
F
C
G
----
G
G
S
L
Q
D
I
Y
H
V
T
G
------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
P
L
S
E
L
Q
I
A
Y
V
S
R
E
T
L
Q
G
L
Y
Y
L
H
S
K
G
K
M
H
R
D
I
K
G
A
N
I
L
L
----
T
D
--
N
---
G
----
H
V
K
L
A
D
F
G
V
S
A
Q
I
T
A
T
I
-----------------------------------------
A
---
A
F
I
G
T
P
Y
W
M
A
P
E
V
A
A
V
E
R---
K
G
G
Y
N
Q
L
C
D
L
W
A
V
G
I
T
A
I
E
L
A
E
L
Q
P
P
M
F
D
L
---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
48
Fugue
51.40
13%
31
- C1 -
-
4BTF
2
MLKL_MOUSE
A:
[7-460]
-------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
D
K
L
G
Q
I
I
K
L
G
Q
L
I
Y
E
Q
C
E
K
M
---
K
---
Y
-
C
R
K
Q
C
Q
R
L
-
G
N
R
V
H
G
L
L
Q
P
L
Q
R
-
L
Q
A
Q
G
K
K
N
L
P
D
D
I
------
T
A
A
L
G
R
F
D
E
V
L
K
E
----
A
N
Q
Q
I
E
K
F
I
L
F
H
E
V
N
E
K
L
R
D
V
W
E
E
L
L
L
L
L
Q
V
P
A
S
W
Q
Q
E
D
R
Q
D
A
E
E
D
G
N
-
E
N
M
K
V
I
L
M
Q
L
Q
I
S
V
E
E
I
N
K
T
L
K
Q
C
S
I
P
Q
D
-
L
Q
I
K
E
I
P
K
E
H
L
G
P
P
W
T
K
L
K
T
S
K
M
S
T
I
Y
R
G
E
Y
H
R
S
--
P
V
T
I
K
--
V
F
N
N
P
Q
A
E
S
V
G
I
V
R
F
T
F
N
D
E
I
K
T
M
K
K
F
D
---
S
P
N
I
L
R
I
F
G
I
C
I
D
Q
-----
T
V
K
P
P
E
F
S
I
V
M
E
Y
C
E
L
G
T
-------
L
R
E
L
L
D
---
R
E
-
K
D
L
T
M
S
V
R
S
L
L
V
L
R
A
A
R
G
L
Y
R
L
H
H
S
E
T
L
H
R
N
I
S
S
S
S
F
L
V
----
A
G
--
G
---
Y
----
Q
V
K
L
A
G
---------------------------------------------
F
E
L
S
K
T
Q
N
S
I
S
R
T
A
S
S
T
I
Y
V
S
P
E
R
L
K
N
P
----
F
C
L
Y
D
I
K
A
E
I
Y
S
F
G
I
V
L
W
E
I
A
T
G
K
I
P
F
E
G
C
D
S
K
K
I
R
E
L
V
A
E
D
-
K
K
Q
E
P
V
G
QD
C
P
E
L
L
R
E
I
I
N
E
C
R
A
H
EP
S
Q
----------
R
P
S
V
D
G
I
L
-
E
R
L
S
A
----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
36
HHSearch
50.34
23%
-103
- C1 -
-
4NIF
-
KS6A1_HUMAN
A:
[7-209]
--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
S
D
G
Y
V
V
K
E
T
I
G
V
G
S
Y
S
E
C
K
R
C
V
H
K
A
T
N
M
E
Y
A
V
K
V
I
D
K
S
K
------------------
R
D
P
-
S
E
E
I
E
I
L
L
R
--
Y
G
-
Q
H
P
N
I
I
T
L
K
D
V
Y
D
------
D
G
K
H
V
Y
L
V
T
E
L
M
R
----
G
G
E
L
L
D
K
I
L
R
Q
K
------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
F
F
S
E
R
E
A
S
F
V
L
H
T
I
G
K
T
V
E
Y
L
H
S
Q
G
V
V
H
R
D
L
K
P
S
N
I
L
Y
----
V
D
--
E
---
S
GNPE
C
L
R
I
C
D
F
G
F
A
K
Q
L
R
A
E
N
-----------------------------------------
G
L
L
M
T
P
C
Y
---
F
V
A
P
E
V
L
K
R
------
Q
G
Y
D
E
G
C
D
I
W
S
L
G
I
L
L
Y
T
M
L
A
G
Y
T
P
F
A
N
G
---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
10
PsiBlast_PDB
50.27
25%
-144
- C- -
-
5CEN
-
M3K12_HUMAN
A:
[204-332]
-------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
A
G
R
---
P
V
T
P
S
L
L
V
D
----
W
S
M
G
I
A
G
G
M
N
Y
L
H
L
H
K
I
I
H
R
D
L
K
S
P
N
M
L
I
----
T
Y
--
D
---
D
----
V
V
K
I
S
D
F
G
T
S
K
E
L
S
------------------------------------------
D
K
S
T
K
M
S
F
A
G
T
V
A
W
M
A
P
E
V
I
R
N
E
----
P
--
V
S
E
K
V
D
I
W
S
F
G
V
V
L
W
E
L
L
T
G
E
I
P
Y
K
D
V
--
D
S
S
A
I
I
W
G
V
G
-
S
N
S
L
H
L
P
--
V
P
---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
43
HHSearch
49.04
24%
0
- C- -
-
5JZN
1
DCLK1_HUMAN
A:
[18-223]
--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
T
E
R
Y
K
V
G
R
T
I
G
D
G
N
F
A
V
V
K
E
C
V
E
R
S
T
A
R
E
Y
A
L
K
I
I
K
K
S
K
--
C
R
-----------
G
K
E
H
M
I
-
Q
N
E
V
S
I
L
R
R
---
V
-
K
H
P
N
I
V
L
L
I
E
E
M
D
------
V
P
T
E
L
Y
L
V
M
E
L
V
K
----
G
G
D
L
F
D
A
I
T
S
T
N
------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
K
Y
T
E
R
D
A
S
G
M
L
Y
N
L
A
S
A
I
K
Y
L
H
S
L
N
I
V
H
R
D
I
K
P
E
N
L
L
V
Y
E
H
Q
D
G
--
S
---
K
----
S
L
K
L
G
D
F
G
L
A
T
I
V
D
G
P
--------------------------------------------
L
Y
T
V
C
G
T
P
T
Y
V
A
P
E
I
I
A
E
------
T
G
Y
G
L
K
V
D
I
W
A
A
G
V
I
T
Y
I
L
L
C
G
F
P
P
F
R
G
S
---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------