@TOME V2.3
(Mar 2018)
Ref.
-
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Doc.
Global output mode :
Sort entries by :
Atome Result
Tools Result
PDB occurence
Core Structure Cluster
Sequence Color type :
Secondary Structure
Hydrophobicity
Disulfide Bonds
TCoffee Identity Score
Uniprot annotation
Core Structure Cluster
Contacts with Ligands
Show alignment :
Atome selection
All alignments
Only Template with Ligand
Column output:
Score:
Atome Rank Value
Tools Score
Hide column
Alignment:
Sequence Identity (%)
Tcoffee Alignment Score
Hide column
3D Common Core:
Tito PKB Score
Verify3D Score
QMean Score
Hide column
Structural Clustering:
Cluster Num
3D-Jury Struct. Score
Hide column
Modeller Result :
Model Rank
QMean Score
Dfire Score
Dope Score
Errat Score
Verify3D Score
Modeller Score
Hide column
Complexes Modeling
Show Ligands of Templates
Complexes Affinity Score
Main Binding Site Identity
Hide column
Templates Information:
Uniprot entry
Cath class
Scop class
Smart class
Prosite class
Pfam class
EC Number
Taxonomy
Experiment Method
Hide column
Sequence & Result Tab:
PDB Template Sequence
Complexes Tab
Values color: [
Good
|
Correct
|
Middling
|
Bad
]
Sequence color :
Mutated
Helix
Strand
Conserved
Query sequence : spr0117: (2017-12-15 )
MIRKLIIFLLMLPLFVLWLELHVLVNNLLLNLESPLDFVISMSLAFFVLILSKIVLDILYALKDLYKKEALITIFPFIFIRRKKVNVRFSPYFSFHRKSLSPDDLRSRIIWSFILEIAIILVFILKIPFAIIMLTTIFFWTIMDINHLVFNKTEFLFNQSKWEKEDSFESDLTNTLKDKIQKSELSYSDLMSLQLYDAMNQSTFLTDSELFEDILKKIEDSHNTLLCTGLVELLLYEMSISNNNNWSNKVDKIRIHLIRINQLDFFYYTSWLRQNFDFCMNREYHKMKSRKLLLSNKKIV
Atome Classification :
(20 SA)
-------------------------.....--------....10........20---..---......30........40........50...-.....60.....--...70........80.-.......90..--------......100..---------.....110.......---120....--------...130.......140....---...150......----.--160.......170.......180-..-------.....190...---....200.......---210......--.220........----230.----......240.--.---.-...---.250.......260.......270.---......280.......290....--...300-------------------------------------------------------
(Atome)
(Ident)
(Tito)
(Num)
(QMean)
(Ligand)
(Uniprot)
-------------------------
M
I
R
K
L
--------
I
I
F
L
L
M
L
P
L
F
V
L
W
L
E
L
---
H
V
---
L
V
N
N
L
L
LNLE
S
P
L
D
F
V
I
S
M
S
L
A
F
F
V
L
I
L
S
K
I
-
V
L
D
I
L
Y
A
L
K
D
L
Y
--KKE
A
L
I
T
I
F
P
F
I
F
I
R
R
-
K
K
V
N
V
R
FS
P
Y
F
--------
S
F
H
RKSL
S
P
D
D
---------
L
R
S
R
I
I
W
S
F
I
L
E
I
A
I
---
I
L
V
F
I
L
K
--------
I
P
F
A
I
I
M
L
T
T
I
F
F
W
T
I
MD
I
N
---
H
L
VFN
K
T
E
F
L
FN----Q--SKWEKEDS
F
E
S
D
L
T
N
T
L
K
D
K
I
Q
K
-SE-------L
S
Y
S
D
L
M
S
L
Q
L
---
Y
D
AMNQSTFL
T
D
S
E
---
L
F
E
D
I
L
K
K
I
--EDS-HNT
L
L
C
T
G
----
L
V
E
L
----
L
L
Y
E
MSISNN--N---N-WSN---K
V
D
K
I
R
I
H
L
I
R
INQ
L
D
F
F
Y
Y
T
S
W
L
R
---
Q
N
F
D
F
C
MN
R
E
Y
H
K
M
K
S
R
K
LLLSN--KKIV---------------------------------------------------------
17
Fugue
87.44
17%
-
- C1 -
-
5AWF
-
SUFB_ECOLI
A:
[34-495]
-----------------LAKGIN
E
E
V
V
R
A
I
S
AKRNEP
E
W
M
L
E
F
R
L
N
A
Y
R
A
W
L
E
M
EEP
H
W
---
L
K
A
H
E
K
L
A
E
Q
G
I
I
F
C
S
F
G
E
A
I
H
D
H
P
E
L
V
R
K
Y
-
L
G
T
V
V
P
G
N
D
N
F
F
A
A
L
N
A
A
V
A
S
D
G
T
F
I
Y
V
P
K
G
V
R
C
P
M
E
L
S
T
Y
F
R
I
NAEKTG
Q
F
E
R
T
I
L
V
A
D
E
D
S
Y
V
S
Y
I
E
G
C
S
A
P
V
R
D
S
Y
Q
L
H
A
A
V
---
V
E
V
I
I
H
K
----------
N
A
E
V
K
Y
S
T
V
Q
N
W
F
P
G
D
N
N
TG
G
I
L
N
F
V
T
K
R
A
L
C
E
GEN
S
K
--
M
S
W
T
Q
S
E
T
G
S
A
I
T
W
K
Y
P
S
C
I
L
-
R
-
G
D
-------
N
S
I
G
E
F
Y
S
V
A
L
T
S
G
H
Q
Q
A
D
T
G
T
K
M
I
H
I
G
KN
T
K
S
T
I
I
S
K
G
I
--
S
A
G
-
H
S
Q
N
S
Y
R
G
----
L
V
K
I
M
PTA
T
N
A
R
N
F
T
Q
C
D
--
S
---
M
-
L
I
G
AN
C
G
A
H
T
F
P
Y
V
E
C
R
N
N
S
A
Q
L
E
H
E
A
T
T
S
R
IG
E
D
Q
L
F
Y
C
L
Q
R
G
I
S
E
E
D
A
I
S
M
I
V
N
G
F
C
K
D
V
F
S
E
LP
L
E
F
A
V
E
A
Q
K
L
L
A
I
S
L
E
H
SVG---------------------------------
21
Fugue
62.52
15%
-
- C2 -
-
4WGV
-
?
A:
[45-439]
VGYMD
P
G
N
W
I
T
S
M
Q
G
G
A
Q
YGYTL
L
F
V
I
L
I
S
--------
S
L
A
A
M
L
L
Q
S
M
T
V
R
L
G
I
---
A
T
GKD
L
A
Q
M
T
R
H
F
L
S
K
P
V
A
I
I
F
W
I
I
A
E
L
A
I
I
A
T
D
I
A
E
V
I
G
S
A
I
A
L
D
L
I
F
--
G
I
P
L
I
V
G
A
L
I
T
V
F
----
D
V
F
L
L
L
F
I
M
R
F
--------
G
F
R
K
I
E
A
I
V
G
T
---------
L
I
F
T
V
L
A
I
F
V
F
E
V
F
I
SSP
Q
L
T
D
I
L
N
GFVPHKEI
V
T
N
Q
G
I
L
Y
I
A
L
G
I
I
G
A
T
I
M
P
---
H
N
L
Y
L
H
S
S
I
V
Q
S
----
R
K
Y
D
R
H
D
N
E
E
K
A
Q
A
I
K
Y
A
T
I
D
S
N
L
Q
L
-
S
I
-------
A
F
V
V
N
C
L
L
L
T
L
---
G
A
A
L
F
F
G
T
K
T
N
D
L
G
---
G
F
Y
D
L
Y
H
A
L
K
T
E
P
V
-
L
G
A
T
L
G
G
V
----
M
S
T
L
----
F
A
V
A
L
L
A
S
G
Q
--
N
---
S
-
T
I
T
---
G
T
L
A
G
Q
I
V
M
E
G
F
L
R
L
S
---
I
P
N
W
L
R
---
R
L
I
T
R
S
L
A
V
I
P
V
I
I
C
L
I
I
F
K
G
N
S
--
E
K
I
E
Q
L
L
V
F
S
Q
V
F
L
S
I
A
L
P
F
S
L
I
P
L
Q
L
A
T
S
N
KKLMGPFI
N
K
T
W
V
N
I
I
S
W
T
L
I
V
I
L
S
G
L
N
V
Y
14
HHSearch
51.57
21%
-192
- C2 -
-
1ZKD
-
?
A:
[5-42]
---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
T
A
L
A
T
E
I
K
R
L
I
K
A
A
G
P
-------
M
P
V
W
R
Y
M
E
L
C
L
---
G
H
P
-------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
22
Fugue
48.70
19%
-93
- C2 -
-
5TCX
1
CD81_HUMAN
A:
[6-232]
--------------------------
S
T
K
S
--------
I
K
Y
L
L
F
V
F
N
F
V
F
W
L
A
G
---
G
V
---
I
L
G
V
A
L
W
L
R
----------------------------------
H
--
P
N
T
F
Y
V
G
I
Y
I
L
I
A
V
G
A
-
V
M
M
F
V
G
F
L
G
Y
G
--------
A
I
Q
Q
----------------------------
L
L
G
---
T
F
F
T
C
L
V
--------
I
L
F
A
C
E
V
A
A
G
I
W
G
F
V
-------------------------------
N
K
D
Q
I
A
K
D
V
K
Q
F
Y
D
Q
A
L
Q
Q
-
A
V
-------
V
D
D
D
A
----------------------------
N
N
A
K
A
V
V
--
K
T
F
-
H
E
T
L
D
C
C
G
----
S
S
T
L
----
T
A
L
T
T
S
V
L
K
N
--
N
LCP
S
-
G
S
N
---
I
I
S
N
L
F
K
E
D
C
H
Q
K
I
D
D
L
F
S
G
K
L
Y
L
I
---
G
I
A
A
I
V
V
A
V
I
M
I
F
E
M
I
L
S
M
V
L
S
S
--
G
I
R
N
---------------------------------------------------------
13
HHSearch
47.77
10%
-173
- C2 -
-
2DOA
-
A:
[12-59]
----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
P
F
R
D
R
V
L
H
L
L
A
L
-
R
P
-------
Y
R
K
A
E
L
L
L
R
L
Q
---
K
D
G
L
T
Q
A
----
D
K
D
---
A
L
D
G
L
L
Q
Q
V
--
A
N
M
-
S
-------------------------------------------------------------------------------------------------------------------------------------------------------------
1
PsiBlast_PDB
46.72
25%
-34
- C2 -
-
3AYF
-
?
A:
[124-220]
---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
A
D
L
T
D
D
E
K
S
I
I
R
E
-
Q
V
-------
I
K
E
---
M
R
K
N
R
---
Y
N
P
V
T
D
V
L
V
L
T
D
A
Q
---
V
Y
G
--
L
E
K
V
--
R
D
Y
-
Y
R
D
V
F
T
N
G
DGWG
L
K
K
G
----
L
I
K
E
S
D
M
P
K
A
--
N
---
R
A
W
V
A
---
D
S
D
Q
I
Q
------
Q
I
A
D
F
F
F
W
T
A
W
L
------------------------------------------------------------------------------------------
2
PsiBlast_PDB
46.09
25%
-32
- C2 -
-
3AYG
-
?
A:
[124-220]
---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
A
D
L
T
D
D
E
K
S
I
I
R
E
-
Q
V
-------
I
K
E
---
M
R
K
N
R
---
Y
N
P
V
T
D
V
L
V
L
T
D
A
Q
---
V
Y
G
--
L
E
K
V
--
R
D
Y
-
Y
R
D
V
F
T
N
G
DGWG
L
K
K
G
----
L
I
K
E
S
D
M
P
K
A
--
N
---
R
A
W
V
A
---
D
S
D
Q
I
Q
------
Q
I
A
D
F
F
F
W
T
A
W
L
------------------------------------------------------------------------------------------
3
PsiBlast_PDB
44.07
27%
77
- C2 -
-
5SZH
-
A:
[60-148]
----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
W
F
K
L
V
L
E
K
N
---
K
L
M
R
Y
E
S
E
L
L
I
M
----
A
--
Q
E
L
E
L
E
D
H
-
Q
S
R
L
E
Q
K
L
R
E
K
M
L
K
-
E
E
SQKD
E
K
D
L
N
E
E
Q
E
V
F
T
E
L
---
M
Q
V
I
E
Q
R
D
K
L
V
D
S
L
---
E
E
Q
R
I
R
E
K
A
--
E
D
----------------------------------------------------------------------------------------------------------------------------------------------------------------
26
Fugue
43.88
18%
-88
* C2 *
-
4WOL
2
TYOBP_HUMAN
A:
[1-33]
--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
C
S
T
V
S
P
G
V
L
A
G
I
V
V
-
G
D
-------
L
V
L
T
V
L
I
A
L
A
V
---
Y
F
L
G
R
L
----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
4
PsiBlast_PDB
42.30
27%
104
- C2 -
-
5SZI
-
B:
[60-150]
----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
W
F
K
L
V
L
E
K
N
---
K
L
M
R
Y
E
S
E
L
L
I
M
----
A
--
Q
E
L
E
L
E
D
H
-
Q
S
R
L
E
Q
K
L
R
E
K
M
L
K
-
E
E
SQKD
E
K
D
L
N
E
E
Q
E
V
F
T
E
L
---
M
Q
V
I
E
Q
R
D
K
L
V
D
S
L
---
E
E
Q
R
I
R
E
K
A
--
E
D
Q
-
H
-------------------------------------------------------------------------------------------------------------------------------------------------------------
24
Fugue
41.69
15%
-16
- C2 -
-
1IC2
-
TPM1_CHICK
A:
[1-79]
-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
M
D
A
I
K
K
K
M
Q
M
L
----
K
--
L
D
K
E
N
A
L
D
R
A
E
Q
A
E
A
D
K
K
A
A
E
E
R
-
S
K
-------
Q
L
E
D
E
L
V
A
L
Q
K
---
K
L
K
G
T
E
D
E
L
D
K
Y
S
E
---
S
L
K
D
A
Q
E
K
L
--
E
L
A
-
D
K
K
A
T
---------------------------------------------------------------------------------------------------------------------------------------------------------
5
PsiBlast_PDB
41.48
27%
84
- C2 -
-
5SZJ
1
B:
[60-150]
----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
W
F
K
L
V
L
E
K
N
---
K
L
M
R
Y
E
S
E
L
L
I
M
----
A
--
Q
E
L
E
L
E
D
H
-
Q
S
R
L
E
Q
K
L
R
E
K
M
L
K
-
E
E
SQKD
E
K
D
L
N
E
E
Q
E
V
F
T
E
L
---
M
Q
V
I
E
Q
R
D
K
L
V
D
S
L
---
E
E
Q
R
I
R
E
K
A
--
E
D
Q
-
H
-------------------------------------------------------------------------------------------------------------------------------------------------------------
6
PsiBlast_PDB
40.63
27%
118
- C2 -
-
5SZK
-
A:
[60-150]
----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
W
F
K
L
V
L
E
K
N
---
K
L
M
R
Y
E
S
E
L
L
I
M
----
A
--
Q
E
L
E
L
E
D
H
-
Q
S
R
L
E
Q
K
L
R
E
K
M
L
K
-
E
E
SQKD
E
K
D
L
N
E
E
Q
E
V
F
T
E
L
---
M
Q
V
I
E
Q
R
D
K
L
V
D
S
L
---
E
E
Q
R
I
R
E
K
A
--
E
D
Q
-
H
-------------------------------------------------------------------------------------------------------------------------------------------------------------
15
HHSearch
40.51
3%
-119
- C2 -
-
1BAZ
-
RARC_BPP22
C:
[14-48]
-------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
W
P
R
E
V
L
D
L
V
R
K
V
A
E
E
-
N
G
-------
R
S
V
N
S
E
I
Y
Q
R
V
---
M
E
S
F
K
K
E
---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
23
Fugue
36.87
16%
166
- C2 -
-
1UIX
-
ROCK2_BOVIN
A:
[-2-1045]
--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
T
--
S
D
V
A
N
L
A
N
E
K
E
E
L
N
N
K
L
K
E
A
Q
E
Q
-
L
S
-------
R
L
K
D
E
E
I
S
A
A
A
---
I
K
A
Q
F
E
K
Q
L
L
T
E
R
T
---
L
K
T
Q
A
V
N
K
L
--
A
E
I
M
N
R
K
-----------------------------------------------------------------------------------------------------------------------------------------------------------
20
Fugue
35.39
12%
16
- C2 -
-
5HDA
-
ZMY11_HUMAN
A:
[3-123]
------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
R
M
K
S
D
H
K
R
E
T
E
R
V
V
R
E
-
A
L
-------
E
K
L
R
S
E
M
E
E
E
K
---
R
Q
A
V
N
K
A
V
A
N
M
Q
G
E
---
M
D
R
K
C
K
Q
V
K
--
E
K
C
-
K
E
E
F
V
E
E
I
----
K
K
L
A
----
T
Q
H
K
Q
L
I
S
Q
T
K
K
K
---
Q
-
W
C
Y
---
N
C
E
E
E
-------
A
M
Y
H
C
C
W
N
T
S
Y
C
S
---
I
K
C
Q
Q
E
H
W
H
A
E
H
K
R
T
C
R
R
K
-------------------------------------------------------------------
19
Fugue
32.69
29%
190
- C2 -
-
5H0N
-
?
B:
[1-31]
-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
M
T
W
E
E
W
D
K
K
I
E
E
Y
T
K
K
I
E
E
L
I
K
K
-
S
Q
-------
N
Q
Q
I
D
L
------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
11
HHSearch
31.75
11%
-147
- C2 -
-
5BQO
-
?
E:
[162-179]
------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
D
-
K
K
E
---
R
F
L
N
L
Y
N
Q
L
L
K
I
R
K
----------------------------------------------------------------------------------------------------
8
HHSearch
31.55
31%
-122
- C2 -
-
2B8I
-
?
A:
[6-37]
--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
K
A
----
L
I
Y
E
T
L
V
N
L
A
--
N
---
Q
-
D
P
E
---
Q
H
A
T
I
R
Q
N
L
Y
--
E
Q
L
D
L
-------------------------------------------------------------------------------------------------
10
HHSearch
28.28
11%
-101
- C2 -
-
5BQP
-
?
D:
[162-178]
------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
D
-
K
K
E
---
R
F
L
N
L
Y
N
Q
L
L
K
I
R
-----------------------------------------------------------------------------------------------------