@TOME V2.3
(Mar 2018)
Ref.
-
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Doc.
Global output mode :
Sort entries by :
Atome Result
Tools Result
PDB occurence
Core Structure Cluster
Sequence Color type :
Secondary Structure
Hydrophobicity
Disulfide Bonds
TCoffee Identity Score
Uniprot annotation
Core Structure Cluster
Contacts with Ligands
Show alignment :
Atome selection
All alignments
Only Template with Ligand
Column output:
Score:
Atome Rank Value
Tools Score
Hide column
Alignment:
Sequence Identity (%)
Tcoffee Alignment Score
Hide column
3D Common Core:
Tito PKB Score
Verify3D Score
QMean Score
Hide column
Structural Clustering:
Cluster Num
3D-Jury Struct. Score
Hide column
Modeller Result :
Model Rank
QMean Score
Dfire Score
Dope Score
Errat Score
Verify3D Score
Modeller Score
Hide column
Complexes Modeling
Show Ligands of Templates
Complexes Affinity Score
Main Binding Site Identity
Hide column
Templates Information:
Uniprot entry
Cath class
Scop class
Smart class
Prosite class
Pfam class
EC Number
Taxonomy
Experiment Method
Hide column
Sequence & Result Tab:
PDB Template Sequence
Complexes Tab
Values color: [
Good
|
Correct
|
Middling
|
Bad
]
Sequence color :
Mutated
Helix
Strand
Conserved
Query sequence : spr0342: (2017-12-20 )
MRKFKIFLFIEACLLTGALILMVSEHFSRFLLILFLFLLLIRYYTGKEGNNLLLVAATILFFFIVMLNPFVILAIFVAVIYSLFLLYPMMNQEKEQTNLVFEEVVTVKKEKNRWFGNLHHFSSYQTCQFDDINLFRFMGKDTIHLERVILTNHDNVIILRKIVGTTKIIVPVDVEVSLSVNCLYGDLTFFNQPKRALRNEHYHQETKDYLKSNKSVKIFLTTMIGDVEVVRG
Atome Classification :
(19 SA)
------------------------------------------.........10...--.....20........30....----....40------------........50....---....60........70........80......-..90........100---..-.....110........----120.-...--...-130.....-----..140.......-------------150...-.....160..--------------......170---------------------------------------..------.--.....180...------------....190.....--------------------.-.--200.......210.......220......--------------.230----------------------------
(Atome)
(Ident)
(Tito)
(Num)
(QMean)
(Ligand)
(Uniprot)
------------------------------------------MR
K
F
K
I
F
L
F
I
E
A
C
L
--
L
T
G
A
L
I
L
M
V
S
E
H
F
S
R
F
L
L
I
L
F
----
L
F
L
L
L
I
------------
R
Y
Y
TGKEGN
N
L
L
L
V
---
A
A
T
I
L
F
F
F
I
V
M
L
N
P
F
V
I
L
A
I
F
V
A
V
I
Y
S
L
F
L
L
Y
-PMMNQ
E
K
E
Q
T
N
L
V
F
E
---
E
V
-
V
T
V
K
KEK-NRWFGNLH----HFSS-YQT--CQF-DD
I
N
L
F
R
F
-----MGKD
T
I
H
L
E
R
V
I
-------------LT-NHD-
N
V
I
I
L
R
-
K
IV--------------GT
T
K
I
I
V
P
----------------------------------------
V
D
------
V
--
E
V
S
L
S
V
N
C
L
Y
G------------DLTFFN
Q
P
K
R
A
L
--------------------
R
-
N
--
E
H
Y
H
Q
E
T
K
D
Y
L
KSNK
S
V
K
I
F
L
T
T
M
IG
D
V
E
--------------VVRG----------------------------
19
Fugue
55.37
16%
5
- C4 -
-
5KNK
6
?
B:
[10-333]
---PDSKSMNYQLLKTFSRQPIQFGRFLARLLAGLVNTLKIT
R
T
S
K
S
I
E
L
N
L
R
I
A
L
PY
L
T
P
Q
Q
R
I
A
I
T
E
K
A
V
R
N
E
L
T
S
Y
----
F
E
F
L
S
I
WGSSNSKNISRI
H
R
I
E
G
E
H
F
F
H
E
A
L
A
---
A
K
K
G
V
V
L
I
V
P
H
F
G
T
W
A
V
M
N
A
W
C
A
Q
F
T
S
M
T
I
L
Y
K
P
V
K
N
A
D
A
D
R
F
V
R
E
A
R
---
S
R
-
E
Q
A
N
L
V
P
-
T
D
E
S
G
V
R
Q
----
I
F
K
A
-
L
K
Q
GE
T
T
V
-
I
L
P
D
H
T
P
N
-----
V
G
G
D
M
V
N
Y
F
G
V
P
-------------
L
A
S
S
N
L
-
S
A
K
L
I
Q
-
K
T
K
AKALFLYAIRNEND
G
F
T
M
H
I
E
P
----------------------------------------
M
D
------
E
--
K
I
Y
E
G
-
T
A
D
D
G
------------
T
Y
V
I
H
Q
A
I
E
Q
L
I
--------------------
Y
-
Q
YP
E
H
Y
H
W
S
Y
K
R
F
K
A
N
P
A
L
D
N
I
Y
N
I
D
P
T
E
A
L
K
--------------
I
V
D
R
LKAEALKTSTQPEPIQTSVM--------
15
Fugue
48.68
12%
-61
- C4 -
-
1POI
-
GCTA_ACIFV
A:
[1-317]
------------------------------------------
S
K
V
M
T
L
K
D
A
I
A
K
Y
V
--
H
S
G
D
H
I
A
L
G
G
F
T
T
D
R
K
P
Y
A
A
V
----
F
E
I
L
R
----------------
Q
G
I
T
D
L
T
G
L
G
G
---
A
A
G
G
D
W
D
M
L
I
G
N
G
R
V
K
A
Y
I
N
C
Y
T
A
N
S
G
V
T
N
V
S
-
R
R
F
R
K
W
F
E
A
G
K
L
T
M
E
---
D
Y
S
Q
D
V
I
Y
M
M
-
W
H
A
A
A
L
G
L
----
P
F
L
P
-
V
T
L
--
M
Q
G
-
S
G
L
T
D
E
W
G
-----
I
S
K
E
V
R
K
T
L
D
K
V
-------------
P
D
-
D
K
F
-
K
Y
I
D
N
P
-
F
K
P
--------------
G
E
K
V
V
A
V
P
V
P
Q
V
D
V
A
I
I
H
A
Q
Q
A
S
PDG
T
V
R
I
W
G
GKFQ
D
V
D
I
A
E
A
AK
Y
T
I
V
T
------
C
--
E
E
I
I
S
D
E
E
I
R
R
------------
D
P
T
K
N
D
I
P
G
M
C
V
D
A
V
V
L
A
P
YGAHP
S
Q
C
Y
GLYD
Y
-
D
--
N
P
F
L
K
V
Y
D
K
V
S
K
T
Q
E
D
F
D
A
F
C
K
E
W
V
F
D
L
K
--------------
D
H
D
E
Y
L
N
K
L
G
A
T
R
L
I
N
L
KVVPGLGYHIDMTKE
14
Fugue
46.82
15%
-12
* C5 *
-
2NC8
-
LPPM_MYCTU
A:
[12-182]
-----------------------------------------------------------------------
G
R
E
N
L
Y
F
Q
----
G
H
M
L
R
V
------------
R
A
S
I
T
I
S
P
D
D
L
V
S
G
-------------------------
E
I
I
A
A
A
K
P
K
N
-
S
K
D
T
G
P
A
L
D
G
D
V
P
F
S
---
Q
K
-
V
A
V
S
N
Y
D
S
D
G
Y
V
G
S
Q
A
----
V
F
S
D
-
L
T
-----
F
-
A
E
L
P
Q
L
A
N
-----
M
N
S
D
A
A
G
V
N
L
S
L
-------------
R
R
-
N
G
N
-
I
V
I
L
E
G
-
R
A
D
--------------
L
T
S
V
S
D
P
D
----------------------------------------
A
D
------
V
--
E
L
T
V
A
----------------------
F
P
A
A
V
T
S
T
--------------------
N
-
G
--
D
R
I
E
P
E
V
V
Q
W
K
L
K
P
G
V
V
S
T
M
S
A
Q
A
R
Y
T
D
P
--------------
N
T
R
S
----------------------------
1
PsiBlast_PDB
44.73
25%
-129
- C6 -
-
4NZR
1
Y281_MYCGE
M:
[178-256]
-------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
Y
D
S
-
Y
P
N
--
H
F
F
-
E
D
V
K
T
L
A
I
-----
D
A
K
D
I
S
A
L
K
T
T
I
-------------
D
S
-
E
K
P
-
T
Y
L
I
I
R
-
G
L
S
--------------
G
N
G
S
Q
L
N
E
----------------------------------------
L
Q
------
L
--
P
E
S
V
K
K
V
S
L
Y
G
------------
D
Y
T
G
V
N
V
A
K
Q
I
F
--------------------
A
-
N
-----------------------------------------------------------------------------
2
PsiBlast_PDB
44.09
25%
-123
- C6 -
-
4NZT
-
Y281_MYCGE
M:
[230-308]
-------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
Y
D
S
-
Y
P
N
--
H
F
F
-
E
D
V
K
T
L
A
I
-----
D
A
K
D
I
S
A
L
K
T
T
I
-------------
D
S
-
E
K
P
-
T
Y
L
I
I
R
-
G
L
S
--------------
G
N
G
S
Q
L
N
E
----------------------------------------
L
Q
------
L
--
P
E
S
V
K
K
V
S
L
Y
G
------------
D
Y
T
G
V
N
V
A
K
Q
I
F
--------------------
A
-
N
-----------------------------------------------------------------------------
6
HHSearch
41.67
36%
-426
- C1 -
-
2MC7
-
?
A:
[19-29]
------------------------------------------------------
L
V
--
L
C
L
A
L
W
Q
I
V
------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
3
HHSearch
41.05
13%
-88
- C3 -
-
4QRK
-
?
A:
[119-220]
-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
S
K
I
--
N
-
L
-
K
E
L
N
V
G
M
G
-----
V
G
K
V
D
L
D
I
S
G
N
Y
----------------
K
N
N
-
V
K
V
N
I
E
-
G
G
V
--------------
G
E
A
T
V
Y
L
P
----------------------------------------
K
S
------
I
--
G
V
K
I
K
A
E
K
G
V
G
------------
A
V
N
A
N
G
F
I
-
V
E
--------------------------
G
E
N
I
Y
K
N
S
Q
Y
G
K
S
K
N
S
I
E
V
N
I
E
A
G
V
G
A
I
N
--------------
I
K
Q
K
----------------------------
17
Fugue
38.64
10%
-30
- C4 -
-
1POI
-
GCTA_ACIFV
A:
[1-317]
SKVMT
L
K
D
A
I
A
K
YVHSGDH
I
A
L
G
G
F
TTDRKP
Y
A
A
V
F
E
I
L
R
Q
G
I
T
D
L
T
G
L
G
G
A
A
G
-----
G
D
W
D
M
L
I
G
N
G
R
V
K
A
Y
I
N
C
Y
T
ANSG
V
T
N
V
S
R
------------
R
F
R
K
W
F
E
A
G
K
L
T
M
E
D
Y
S
Q
D
V
I
Y
M
M
W
H
A
A
A
L
G
L
P
F
L
P
V
T
L
M
Q
G
S
G
L
T
D
E
W
-
G
I
S
K
E
V
R
K
T
L
D
K
V
P
D
DK
F
K
Y
-
I
D
N
P
F
K
P
-
G
E
K
V
V
A
V
P
V
P
Q
V
D
V
A
I
-
I
H
A
--
Q
Q
A
-
S
P
D
G
T
V
R
I
-----
W
G
G
-
K
F
Q
D
V
D
I
A
-------------
E
A
-
A
K
Y
-
T
I
V
T
C
E
-
E
I
I
--------------
S
D
E
E
I
R
R
D
----------------------------------------
P
T
KNDIPG
M
--
C
V
D
A
V
V
L
A
P
Y
G
AHP
S
Q
C
Y
GLYDY
D
N
P
F
L
K
V
Y
D
K
V
S
--------------------
K
T
Q
--
E
D
F
D
A
F
C
K
E
W
V
F
D
L
K
D
H
D
E
Y
L
N
K
L
G
A
T
R
L
I
N
L
KVVPGLGYHID
M
T
K
E
----------------------------
16
Fugue
34.32
10%
-52
- C4 -
-
1FEW
-
DBLOH_HUMAN
A:
[12-184]
-----------------------------------S
L
S
S
E
A
L
M
R
R
A
V
S
L
V
T
D
S
T
S
T
--
F
L
S
Q
T
T
Y
A
L
I
E
A
I
T
E
Y
T
K
A
V
Y
----
T
L
T
S
L
Y
------------
R
Q
Y
T
S
L
L
G
K
M
---------------------------------------------
N
S
E
E
E
D
E
V
W
Q
---
V
I
-
I
G
A
R
A
E
M
-
T
S
K
H
Q
E
Y
L
----
K
L
E
T
-
T
W
M
--
T
A
V
-
G
L
S
E
M
A
A
E
-----
A
A
Y
Q
T
G
A
D
Q
A
S
I
-------------
T
A
-
R
N
H
-
I
Q
L
V
K
L
-
Q
V
E
--------------
E
V
H
Q
L
S
R
K
----------------------------------------
A
E
------
T
--
K
L
A
E
A
------------------
Q
I
E
E
L
K
Q
K
T
Q
E
E
--------------------
G
-
E
--
E
R
A
E
S
E
Q
E
A
Y
L
R
E
D
-------------------------------------------------------------
4
HHSearch
31.51
18%
-174
- C3 -
-
4QRK
-
?
A:
[104-161]
---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
E
I
K
L
S
L
G
-----
T
G
E
F
K
A
D
L
S
K
I
N
-------------
L
K
------
E
L
N
V
G
-
M
G
V
--------------
G
K
V
D
L
D
I
S
----------------------------------------
G
N
------
Y
K
N
N
V
K
V
N
I
E
G
G
V
G
------------
E
A
T
V
Y
-----------------------------------------------------------------------------------------------------------
18
Fugue
24.68
17%
-37
- C2 -
-
1NY4
-
RS28_PYRHO
A:
[1-71]
-------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
M
----
A
E
D
E
-
G
Y
P
--
A
E
V
-
I
E
I
I
G
R
T
G
-----
T
T
G
D
V
T
Q
V
K
V
R
I
-------------
L
E
-
G
R
D
K
G
R
V
I
R
R
-
N
V
R
--------------
G
P
V
R
V
----------------------------------------------------------------
G
------------
D
I
L
I
L
R
E
T
E
R
E
A
--------------------
R
-
E
--
I
K
S
R
R
----------------------------------------------------------------------
21
Fugue
23.73
16%
8
* C4 *
-
5H0N
-
?
B:
[1-31]
-------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
M
T
W
E
E
W
D
K
--------------------
K
-
I
--
E
E
Y
T
K
K
I
E
E
L
I
K
K
S
Q
N
Q
Q
I
D
L
------------------------------------------------------
20
Fugue
23.68
15%
-61
- C5 -
-
2LV2
-
A:
[1-85]
---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
M
G
H
H
H
----
H
H
H
S
-
H
M
G
---
D
G
-
E
G
A
G
V
L
G
L
-----
S
A
S
A
E
C
H
L
C
P
V
C
-------------
G
E
-
S
F
A
-
S
K
G
A
Q
E
-
R
H
L
--------------
R
L
------------------------------------------------------
L
--
H
A
A
Q
V
F
P
C
K
Y
C
------------
P
A
T
F
Y
S
S
P
G
L
T
R
--------------------
H
-
I
--
N
K
C
H
P
S
E
N
R
------------------------------------------------------------------
10
HHSearch
18.48
9%
16
- C3 -
-
4OPW
2
?
A:
[190-223]
------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
E
V
N
C
K
I
T
G
K
--------------
G
S
A
Q
I
H
P
T
----------------------------------------
D
N
------
L
--
K
A
T
I
---
V
G
K
G
------------
N
I
R
Y
K
G
----------------------------------------------------------------------------------------------------------
11
HHSearch
17.93
9%
35
* C3 *
-
4OPW
2
?
B:
[190-223]
------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
E
V
N
C
K
I
T
G
K
--------------
G
S
A
Q
I
H
P
T
----------------------------------------
D
N
------
L
--
K
A
T
I
---
V
G
K
G
------------
N
I
R
Y
K
G
----------------------------------------------------------------------------------------------------------
9
HHSearch
14.25
13%
-3
* C6 *
-
4XTR
-
?
G:
[15-29]
-----------------------------------------------------------------------------------------------------------
R
W
R
V
Y
L
L
I
---
V
L
L
V
M
L
L
--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
7
HHSearch
14.16
9%
-
- C3 -
-
4DLH
-
?
A:
[114-185]
------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
F
V
P
F
T
D
E
T
----
T
-
D
D
G
R
T
Y
--
E
-
H
G
R
Y
L
D
V
D
P
A
G
ADG-
G
D
E
V
A
L
D
F
N
L
A
Y
N
P
FCAYGGS
F
S
C
A
L
P
-
P
A
D
-
N
H
V
P
A
A
-
I
T
A
--------------
G
E
R
-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
5
HHSearch
9.07
11%
14
- C3 -
-
2LNU
-
?
A:
[108-179]
----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
L
-
F
V
P
F
R
D
K
T
----
T
-
G
Q
-
Q
S
Y
--
D
-
G
G
R
Y
M
E
L
E
P
D
R
D
L
S
D
G
D
E
I
T
L
D
F
N
L
A
Y
SP
F
C
A
Y
S
DTFS
C
P
L
P
-
P
E
S
-
N
W
L
E
T
A
-
V
T
A
--------------
G
E
------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
8
HHSearch
8.71
9%
-5
- C3 -
-
2LOK
-
?
A:
[114-185]
------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
F
V
P
F
T
D
E
T
----
T
-
D
D
G
R
T
Y
--
E
-
H
G
R
Y
L
D
V
D
P
A
GADG-
G
D
E
V
A
L
D
F
N
L
A
Y
NPFCAYG
G
S
F
S
C
A
L
P
-
P
A
D
-
N
H
V
P
A
A
-
I
T
A
--------------
G
E
R
-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------