@TOME V2.3
(Mar 2018)
Ref.
-
-
Doc.
Global output mode :
Sort entries by :
Atome Result
Tools Result
PDB occurence
Core Structure Cluster
Sequence Color type :
Secondary Structure
Hydrophobicity
Disulfide Bonds
TCoffee Identity Score
Uniprot annotation
Core Structure Cluster
Contacts with Ligands
Show alignment :
Atome selection
All alignments
Only Template with Ligand
Column output:
Score:
Atome Rank Value
Tools Score
Hide column
Alignment:
Sequence Identity (%)
Tcoffee Alignment Score
Hide column
3D Common Core:
Tito PKB Score
Verify3D Score
QMean Score
Hide column
Structural Clustering:
Cluster Num
3D-Jury Struct. Score
Hide column
Modeller Result :
Model Rank
QMean Score
Dfire Score
Dope Score
Errat Score
Verify3D Score
Modeller Score
Hide column
Complexes Modeling
Show Ligands of Templates
Complexes Affinity Score
Main Binding Site Identity
Hide column
Templates Information:
Uniprot entry
Cath class
Scop class
Smart class
Prosite class
Pfam class
EC Number
Taxonomy
Experiment Method
Hide column
Sequence & Result Tab:
PDB Template Sequence
Complexes Tab
Values color: [
Good
|
Correct
|
Middling
|
Bad
]
Sequence color :
Mutated
Helix
Strand
Conserved
Query sequence : B0VKA2: (2017-10-25 )
MSMLALISPAKTLDYETALPTDEFTQPRLLEHSAQLIDVCRKLSASEIASLMSVSEKIATLNADRFRDWKPEFDFSNARQAIYAFKGDVYTGLDAYHLKDKDIDFAQQHLRMLSGLYGLLRPLDLMMPYRLEMGTKLKNTHGHNLYEFWGDIITNQINEDLAAIKSELLVNLASDEYYKSVNEKKIKAEIVKPVFLDQKNGKYKVISFYAKKARGLMARFIVENQLNKVEDIKAFNTEGYYFDADNSSAKELVFKRDEQ
Atome Classification :
(20 SA)
--------.........10.-.......20-.........30.-........40.---.......------------50-........---------60--------........70...-----.....80........90.......--.100.......110.--....-----------..--120......-.130.......140.....----....--150.....---..160.......170..--...---..180.--......190--.....------------..200---........210------------..------------------------.....220.......230--....--------.....------------240.........250.......-----------------
(Atome)
(Ident)
(Tito)
(Num)
(QMean)
(Ligand)
(Uniprot)
--------M
S
M
L
ALISPAKT-LDYETALP--TDEFTQ
P
R
L
L
-
E
-
H
S
A
Q
L
I
D
V
C
R
K---L
S
A
S
E
I
A
------------
S
L
-
M
S
V
S
E
K
I
A
---------TL--------
N
A
D
R
FRDWKPEFD-----FSN
A
R
Q
A
I
Y
A
FKGDVYTGL
D
A
YHL--KDK
D
I
D
F
A
Q
Q
H
L
R
M
L
--
S
G
L
Y
-----------
G
L
--
L
R
P
L
D
L
MM
P
-
Y
R
LEMGTKLKNT--HGH
N
L
----
Y
E
F
W
--
G
D
I
I
T
N
Q
I
---
N
E
D
L
A
A
I
K
S
E
L
L
V
NLA
S
--
D
E
Y
---
Y
K
S
V
N
E
--
K
K
I
K
A
E
IV
K
--
P
V
F
L
D------------QKNG----
K
Y
K
V
I
S
F
Y
A
K
K
------------
A
R
------------------------
G
L
M
A
R
F
I
V
E
N
Q
LN
K
V
E
----
D
I
K
A--------FNTE
G
------------
Y
--
Y
FDADNS
S
A
K
E
L
V
FKRDEQ-----------------
31
HHSearch
87.25
65%
-115
- C2 -
-
5CAJ
1
YAAA_ECOLI
A:
[19-276]
--------
S
H
M
L
I
L
I
S
P
A
K
T
-
L
D
Y
Q
S
P
L
T
--
T
T
R
Y
T
L
P
E
L
L
-
D
-
N
S
Q
Q
L
I
H
E
A
R
K
---
L
T
P
P
Q
I
S
------------
T
L
-
M
R
I
S
D
K
L
A
---------
G
I
--------
N
A
A
R
F
H
D
W
Q
P
D
F
T
-----
P
A
N
A
R
Q
A
I
L
A
F
K
G
D
V
Y
T
G
L
Q
A
E
T
F
--
S
E
D
D
F
D
F
A
Q
Q
H
L
R
M
L
--
S
G
L
Y
-----------
G
V
--
L
R
P
L
D
L
M
Q
P
-
Y
R
L
E
M
G
I
R
L
E
N
A
--
R
G
K
D
L
----
Y
Q
F
W
--
G
D
I
I
T
N
K
L
---
N
E
A
L
A
A
Q
G
D
N
V
V
I
N
L
A
S
--
D
E
Y
---
F
K
S
V
K
P
--
K
K
L
N
A
E
I
I
K
--
P
V
F
L
D
------------
E
K
N
G
----
K
F
K
I
I
S
F
Y
A
K
K
------------
A
R
------------------------
G
L
M
S
R
F
I
I
E
N
R
L
T
K
P
E
----
Q
L
T
G
--------
F
N
S
E
G
------------
Y
--
F
F
D
E
D
S
S
S
N
G
E
L
V
F
K
R
Y
E
------------------
1
PsiBlast_PDB
85.87
63%
-115
- C2 -
-
5CAJ
1
YAAA_ECOLI
A:
[22-276]
-----------
L
I
L
I
S
P
A
K
T
-
L
D
Y
Q
S
P
L
T
--
T
T
R
Y
T
L
P
E
L
L
-
D
-
N
S
Q
Q
L
I
H
E
A
R
K
---
L
T
P
P
Q
I
S
------------
T
L
-
M
R
I
S
D
K
L
A
---------
G
I
--------
N
A
A
R
F
H
D
W
Q
P
D
F
T
-----
P
A
N
A
R
Q
A
I
L
A
F
K
G
D
V
Y
T
G
L
Q
A
E
T
F
--
S
E
D
D
F
D
F
A
Q
Q
H
L
R
M
L
--
S
G
L
Y
-----------
G
V
--
L
R
P
L
D
L
M
Q
P
-
Y
R
L
E
M
G
I
R
L
E
N
A
--
R
G
K
D
L
----
Y
Q
F
W
--
G
D
I
I
T
N
K
L
---
N
E
A
L
A
A
Q
G
D
N
V
V
I
N
L
A
S
--
D
E
Y
---
F
K
S
V
K
P
--
K
K
L
N
A
E
I
I
K
--
P
V
F
L
D
------------
E
K
N
G
----
K
F
K
I
I
S
F
Y
A
K
K
------------
A
R
------------------------
G
L
M
S
R
F
I
I
E
N
R
L
T
K
P
E
----
Q
L
T
G
--------
F
N
S
E
G
------------
Y
--
F
F
D
E
D
S
S
S
N
G
E
L
V
F
K
R
Y
E
------------------
35
HHSearch
37.17
13%
-70
- C2 -
-
4KA4
1
E:
[12-41]
-----------------------------------------Q
Q
-
R
E
E
D
I
Y
R
F
L
K
D
NGP
Q
R
A
L
V
I
A
------------
Q
A
-
L
G
M
R
T
----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
36
HHSearch
36.22
13%
-72
- C2 -
-
3EYI
-
B:
[4-38]
------------------------------------
S
P
Q
F
S
-
Q
Q
R
E
E
D
I
Y
R
F
L
K
D
NGP
Q
R
A
L
V
I
A
------------
Q
A
-
L
G
M
R
T
----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
29
Fugue
35.53
20%
35
- C2 -
-
5IWZ
-
SYCP2_MOUSE
A:
[4-397]
-M
P
V
R
P
D
L
Q
Q
L
E
K
C
I
D
D
A
L
R
K
N
D
F
K
P
L
L
A
L
L
Q
I
D
I
C
E
D
V
K
I
-
K
-
C
S
K
Q
F
L
R
K
L
D
D
---
L
I
C
R
E
L
N
K
KD
I
Q
T
V
S
S
I
L
I
S
I
-
G
R
C
S
K
N
I
F
ILGQA
G
L
Q
T
M
I
--------
K
Q
G
L
V
Q
K
M
V
S
W
F
E
N
S
K
EI
I
L
N
Q
D
E
A
V
M
N
M
I
E
D
L
F
D
L
L
M
V
I
Y
D
I
S
D
E
G
K
N
Q
V
L
E
S
F
I
P
Q
I
--
C
A
L
V
I
DSRVN
F
C
I
Q
Q
E
A
--
L
K
K
M
N
L
M
L
D
R
I
N
Q
E
M
L
T
L
M
S
N
M
--
G
E
R
I
L
DVGD
Y
E
L
Q
--
V
G
I
V
E
A
L
C
---
R
M
T
T
E
K
R
R
Q
E
L
A
Y
E
W
F
S
--
M
D
F
---
I
A
N
A
F
K
E
I
K
D
C
E
F
E
T
D
C
--
R
I
F
L
N
------------
L
V
N
G
I
L
GD
K
R
R
V
Y
T
F
P
C
L
S
------------
A
F
LGK
Y
E
L
Q
I
PSDEKLEEF
W
I
D
F
N
LG
S
H
T
L
S
F
Y
I
E
A
V
T
V
P
E
E
----
K
V
Q
M
--------
Y
N
I
E
V
R
ES
K
K
L
L
T
L
T
L
K
N
--
I
V
K
I
S
K
K
E
G
K
E
L
L
F
Y
F
D
E
S
LE
I
T
N
V
T
K
K
V
FGGLEHH
27
Fugue
33.30
14%
-28
- C2 -
-
3WZM
-
?
A:
[15-278]
--------
M
R
T
R
S
T
I
S
T
P
N
G
-
I
T
W
Y
Y
E
Q
E
--
G
---
T
G
P
D
V
V
-
L
-
V
P
D
G
L
G
E
--
C
Q
---
M
F
D
S
S
V
S
------------
Q
I
-
A
A
Q
G
F
R
V
T
---------
T
F
--------
D
M
---------
P
G
-----
M
S
R
S
A
K
A
----
P
P
E
T
Y
T
E
V
T
A
Q
K
L
--
A
S
Y
V
I
S
V
L
D
A
L
D
I
K
H
--
A
T
V
W
-----------
G
C
--
A
S
G
A
S
T
V
V
A
-
L
L
L
G
Y
P
D
R
I
R
N
A
--
M
C
H
E
L
----
P
T
K
L
--
L
D
H
L
S
N
T
A
VLE
D
E
E
I
S
K
I
L
A
N
V
M
L
N
D
V
S
GG
S
E
A
---
W
Q
A
M
G
---
D
E
V
H
A
R
L
H
K
N
Y
P
V
W
A
R
G
YPRTIPPSAPV
K
D
L
E
----
A
L
R
G
K
P
L
D
W
T
V
------------
G
A
------------------------
A
T
P
T
E
S
F
F
D
N
I
V
T
A
T
K
A
G
V
-
N
I
G
L
--------
L
P
G
M
H
------------
F
--
P
Y
V
S
H
P
D
V
F
A
K
Y
V
V
E
T
T
Q
K
H
L---------------
34
HHSearch
31.50
13%
-81
- C2 -
-
4KA4
-
ZBP1_HUMAN
A:
[10-41]
---------------------------------------
F
S
Q
Q
-
R
E
E
D
I
Y
R
F
L
K
D
N
GP
Q
R
A
L
V
I
A
------------
Q
A
-
L
G
M
R
T
----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
33
HHSearch
30.89
13%
-47
* C2 *
-
2L4M
-
ZBP1_HUMAN
A:
[103-136]
-------------------------------------
P
Q
F
S
-
Q
Q
R
E
E
D
I
Y
R
F
L
K
D
NGP
Q
R
A
L
V
I
A
------------
Q
A
-
L
G
M
R
T
----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
11
PsiBlast_PDB
30.33
31%
-110
- C3 -
-
3MN3
-
SNF1_YEAST
A:
[255-295]
-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
E
S
I
P
--
V
L
F
K
N
------------
I
S
N
G
----
V
Y
T
L
P
K
F
L
S
P
G
------------
A
A
------------------------
G
L
I
K
R
M
L
I
V
N
P
L
N
R
I
-------------------------------------------------------------------------
17
PsiBlast_PDB
29.69
23%
-13
- C2 -
-
2OFC
2
?
A:
[40-141]
----------------------------------------------------------------------------------------------------------------------------------------------------------------
Q
H
V
L
T
M
GG
S
G
T
S
-----------
G
T
--
L
R
--------
F
H
A
D
N
G
E
S
F
T
A
T
--
F
G
V
H
N
----
Y
K
R
W
--
C
D
I
V
T
N
--------
L
A
A
D
E
T
G
M
V
I
N
-----
Q
Q
Y
---
Y
S
Q
K
N
R
--
E
E
A
R
E
R
Q
L
S
--
N
Y
E
V
K
------------
N
A
K
G
----
R
N
F
E
I
V
Y
T
E
A
E
------------
G
N
------------------------
D
L
H
A
N
L
I
I
--------------------------------------------------------------------------------
13
PsiBlast_PDB
29.66
23%
-18
- C2 -
-
4Z2Q
2
?
A:
[39-140]
----------------------------------------------------------------------------------------------------------------------------------------------------------------
Q
H
V
L
T
M
GG
S
G
T
S
-----------
G
T
--
L
R
--------
F
H
A
D
N
G
E
S
F
T
A
T
--
F
G
V
H
N
----
Y
K
R
W
--
C
D
I
V
T
N
--------
L
A
A
D
E
T
G
M
V
I
N
-----
Q
Q
Y
---
Y
S
Q
K
N
R
--
E
E
A
R
E
R
Q
L
S
--
N
Y
Q
V
K
------------
N
A
K
G
----
R
N
F
Q
I
V
Y
T
E
A
E
------------
G
N
------------------------
D
L
H
A
N
L
I
I
--------------------------------------------------------------------------------
20
PsiBlast_PDB
29.65
37%
-110
- C3 -
-
1GTM
-
DHE3_PYRFU
A:
[262-317]
------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
K
W
K
N
E
--
H
G
-
S
V
----
K
D
F
P
--
G
--
A
T
N
I
T
---
N
E
E
L
L
E
L
E
V
D
V
L
A
P
A
A
I
--
E
E
V
---
I
T
K
K
N
A
--
D
N
I
K
A
K
I
V
A
--
E
V
----------------------------------------------------------------------------------------------------------------------------------------------------------------
26
Fugue
29.48
14%
37
- C2 -
-
4INO
-
?
A:
[34-335]
Q
E
V
K
V
K
D
Y
F
G
E
Q
T
I
K
L
P
V
S
K
-
I
I
Y
L
G
S
F
A
--
E
----
V
P
A
M
F
-
H
-
T
W
D
R
V
V
G
I
S
D
Y
---
A
F
K
S
D
I
V
------------
K
A
T
L
K
D
P
E
R
I
K
---------
P
M
S
SDHAAAL
N
V
E
L
L
K
K
L
S
P
D
L
V
-----
V
T
F
V
G
N
P
K
A
V
E
H
A
K
K
F
-
G
I
S
F
L
S
F
--
Q
E
K
T
I
A
E
V
M
E
D
I
D
T
Q
--
A
K
A
L
-----------
E
V
DA
S
K
K
L
A
K
M
Q
E
-
T
L
D
F
I
A
E
R
L
K
G
V
--
K
K
K
K
G
----
V
E
L
F
HK
A
N
K
I
S
G
H
Q
---
A
L
D
S
D
I
L
E
K
G
G
I
D
N
F
G
L
--
K
Y
V
KF
G
R
A
D
I
S
V
--
E
K
I
V
K
E
N
P
E
--
I
I
F
I
W
WISPLS
P
E
D
V
--
L
N
N
P
----
K
F
A
T
I
K
A
I
K
N
K
Q
V
Y
K
L
P
TMDIGG
P
R
------------------------
A
P
L
I
S
L
F
I
A
L
K
A
H
P
E
A
FKGV
D
I
N
A
--------
I
V
K
D
Y
------------
Y
K
V
V
F
D
L
N
D
A
E
V
E
P
F
L
W
H
---------------------
16
PsiBlast_PDB
29.33
23%
-20
- C2 -
-
4Z2S
2
?
A:
[40-141]
----------------------------------------------------------------------------------------------------------------------------------------------------------------
Q
H
V
L
T
M
GG
S
G
T
S
-----------
G
T
--
L
R
--------
F
H
A
D
N
G
E
S
F
T
A
T
--
F
G
V
H
N
----
Y
K
R
W
--
C
D
I
V
T
N
--------
L
A
A
D
E
T
G
M
V
I
N
-----
Q
Q
Y
---
Y
S
Q
K
N
R
--
E
E
A
R
E
R
Q
L
S
--
N
Y
Q
V
K
------------
N
A
K
G
----
R
N
F
Q
I
V
Y
T
E
A
E
------------
G
N
------------------------
D
L
H
A
N
L
I
I
--------------------------------------------------------------------------------
19
PsiBlast_PDB
29.16
23%
-13
- C2 -
-
2OFE
1
?
A:
[40-141]
----------------------------------------------------------------------------------------------------------------------------------------------------------------
Q
H
V
L
T
M
GG
S
G
T
S
-----------
G
T
--
L
R
--------
F
H
A
D
N
G
E
S
F
T
A
T
--
F
G
V
H
N
----
Y
K
R
W
--
C
D
I
V
T
N
--------
L
A
A
D
E
T
G
M
V
I
N
-----
Q
Q
Y
---
Y
S
Q
K
N
R
--
E
E
A
R
E
R
Q
L
S
--
N
Y
E
V
K
------------
N
A
K
G
----
R
N
F
E
I
V
Y
T
E
A
E
------------
G
N
------------------------
D
L
H
A
N
L
I
I
--------------------------------------------------------------------------------
12
PsiBlast_PDB
29.09
23%
-18
- C2 -
-
4YLD
-
?
A:
[39-140]
----------------------------------------------------------------------------------------------------------------------------------------------------------------
Q
H
V
L
T
M
GG
S
G
T
S
-----------
G
T
--
L
R
--------
F
H
A
D
N
G
E
S
F
T
A
T
--
F
G
V
H
N
----
Y
K
R
W
--
C
D
I
V
T
N
--------
L
A
A
D
E
T
G
M
V
I
N
-----
Q
Q
Y
---
Y
S
Q
K
N
R
--
E
E
A
R
E
R
Q
L
S
--
N
Y
Q
V
K
------------
N
A
K
G
----
R
N
F
Q
I
V
Y
T
E
A
E
------------
G
N
------------------------
D
L
H
A
N
L
I
I
--------------------------------------------------------------------------------
18
PsiBlast_PDB
28.47
23%
-11
- C2 -
-
2OFD
1
?
A:
[40-141]
----------------------------------------------------------------------------------------------------------------------------------------------------------------
Q
H
V
L
T
M
GG
S
G
T
S
-----------
G
T
--
L
R
--------
F
H
A
D
N
G
E
S
F
T
A
T
--
F
G
V
H
N
----
Y
K
R
W
--
C
D
I
V
T
N
--------
L
A
A
D
E
T
G
M
V
I
N
-----
Q
Q
Y
---
Y
S
Q
K
N
R
--
E
E
A
R
E
R
Q
L
S
--
N
Y
E
V
K
------------
N
A
K
G
----
R
N
F
E
I
V
Y
T
E
A
E
------------
G
N
------------------------
D
L
H
A
N
L
I
I
--------------------------------------------------------------------------------
15
PsiBlast_PDB
27.20
23%
-12
- C2 -
-
4Z2F
-
?
A:
[40-141]
----------------------------------------------------------------------------------------------------------------------------------------------------------------
Q
H
V
L
T
M
GG
S
G
T
S
-----------
G
T
--
L
R
--------
F
H
A
D
N
G
E
S
F
T
A
T
--
F
G
V
H
N
----
Y
K
R
W
--
C
D
I
V
T
N
--------
L
A
A
D
E
T
G
M
V
I
N
-----
Q
Q
Y
---
Y
S
Q
K
N
R
--
E
E
A
R
E
R
Q
L
S
--
N
Y
Q
V
K
------------
N
A
K
G
----
R
N
F
Q
I
V
Y
T
E
A
E
------------
G
N
------------------------
D
L
H
A
N
L
I
I
--------------------------------------------------------------------------------
10
PsiBlast_PDB
26.65
31%
-78
- C3 -
-
3DAE
-
SNF1_YEAST
A:
[255-295]
-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
E
S
I
P
--
V
L
F
K
N
------------
I
S
N
G
----
V
Y
T
L
P
K
F
L
S
P
G
------------
A
A
------------------------
G
L
I
K
R
M
L
I
V
N
P
L
N
R
I
-------------------------------------------------------------------------
22
Fugue
26.49
14%
0
- C- -
-
1ML9
6
DIM5_NEUCR
A:
[9-282]
-----------
Q
L
P
I
S
I
V
N
R
-
E
D
D
A
F
L
N
P
--
N
F
R
F
I
D
H
S
I
I
-
G
-
K
N
V
P
V
A
D
Q
S
F
R
---
V
G
C
S
C
A
S
------------
D
E
-
E
C
M
Y
S
T
C
Q
---------
C
L
DEMA----
P
D
K
R
F
A
Y
Y
S
Q
G
A
K
-----
K
G
L
L
R
D
R
V
L
Q
S
Q
E
P
I
Y
E
C
H
Q
G
C
A
C
--
S
K
D
C
P
N
R
V
V
E
R
---------------------
G
R
--
T
V
P
L
Q
I
F
R
T
-
K
D
R
G
W
G
V
K
C
P
V
N
I
K
R
G
Q
F
V
----
D
R
Y
L
--
G
E
I
I
T
------
S
E
E
A
D
R
R
R
A
E
S
T
I
A
R
R
K
--
D
V
Y
---
L
F
A
L
D
K
--
F
S
D
P
----
D
--
S
L
D
P
L
------------
L
A
G
Q
----
P
L
E
V
D
G
----
E
------------
Y
M
------------------------
S
G
P
T
R
F
I
N
H
S
C
D
P
N
M
A
----
I
F
A
R
V
G
DHADKH
I
H
D
L
A
------------
L
--
F
A
I
K
D
I
P
K
G
T
E
L
T
F
D
Y
V
N
------------------