@TOME V2.3
(Mar 2018)
Ref.
-
-
Doc.
Global output mode :
Sort entries by :
Atome Result
Tools Result
PDB occurence
Core Structure Cluster
Sequence Color type :
Secondary Structure
Hydrophobicity
Disulfide Bonds
TCoffee Identity Score
Uniprot annotation
Core Structure Cluster
Contacts with Ligands
Show alignment :
Atome selection
All alignments
Only Template with Ligand
Column output:
Score:
Atome Rank Value
Tools Score
Hide column
Alignment:
Sequence Identity (%)
Tcoffee Alignment Score
Hide column
3D Common Core:
Tito PKB Score
Verify3D Score
QMean Score
Hide column
Structural Clustering:
Cluster Num
3D-Jury Struct. Score
Hide column
Modeller Result :
Model Rank
QMean Score
Dfire Score
Dope Score
Errat Score
Verify3D Score
Modeller Score
Hide column
Complexes Modeling
Show Ligands of Templates
Complexes Affinity Score
Main Binding Site Identity
Hide column
Templates Information:
Uniprot entry
Cath class
Scop class
Smart class
Prosite class
Pfam class
EC Number
Taxonomy
Experiment Method
Hide column
Sequence & Result Tab:
PDB Template Sequence
Complexes Tab
Values color: [
Good
|
Correct
|
Middling
|
Bad
]
Sequence color :
Mutated
Helix
Strand
Conserved
Query sequence : B0VL04: (2017-10-30 )
MDALELKNIISDGLLSFPVTDFDQNGDFNKSSYAKRLEWLAPYGASALFAAGGTGEFFSLTGNEYSEVIKTAVDICKGSVPIIAGAGGPTRQAIEQAKEAERLGAHGILLMPHYLTEASQEGLIEHVKQVCNSVDFGVIFYNRSVSRLNLDSIQKLTEMCPNLIGFKDSSGQIDMMTAVTQTIGDRLSYLGGLPTAEVFAAPYKALGCPVYSSAVFNFIPKTAMEFYNALRSDDFETTNRLIKDFFLPLIKIRDRKSGYAVSMIKAGAKIVGHDAGPVRPPLSDLTQADYEDLAALIATLGPQ
Atome Classification :
(21 SA)
.........10........20........30........40........50........60........70........80.....-..-.90........100.......110.......120.......130.......140---.---......150.......160.......170.......180..-.....190......--.200-.......210.......220.......230.......240-.......250.......260.......270.......280.......290.......300.-
(Atome)
(Ident)
(Tito)
(Num)
(QMean)
(Ligand)
(Uniprot)
M
D
A
L
E
L
K
N
I
I
S
D
G
L
LSFPVTDFDQNGDF
N
K
S
S
Y
A
K
R
L
E
W
LAPYGA
S
A
L
F
AAGGTG
E
F
F
S
LTG
N
E
Y
S
E
V
I
K
T
A
V
D
I
CKGSV
P
I
I
AGA-GG-
P
T
R
Q
A
I
E
Q
A
K
E
A
E
R
LGAH
G
I
L
L
M
P
H
Y
L
T
E
A
S
Q
E
G
L
I
E
H
V
K
Q
V
C
NSVD
F
G
V
I
F
YN---R---SVSRL
N
L
D
S
I
Q
K
L
T
E
MC
P
N
L
IGFKDSSG
Q
I
D
M
M
T
A
V
T
Q
T
I
G
-
D
R
L
S
Y
LGGL
P
T
A
E
V
--
F
AA
P
-
Y
K
ALGC
P
V
Y
S
S
A
V
F
N
F
I
P
K
T
A
M
E
F
Y
N
A
L
RSD
D
F
E
T
T
N
R
L
I
-
K
D
F
F
L
P
L
I
KIRDRKSGY
A
V
S
M
I
KAG
A
K
IVGHDAGPVRP
P
L
S
D
L
T
Q
A
D
Y
E
D
L
A
A
L
I
A
TLGPQ-
1
PsiBlast_PDB
96.22
50%
-134
- C7 -
-
4UR8
1
KDGD_AGRFC
A:
[1-298]
M
D
P
E
Q
I
K
T
A
L
G
S
G
L
L
S
F
P
V
T
H
F
D
A
E
G
R
F
A
A
D
S
Y
R
E
H
V
E
W
L
A
G
Y
K
A
P
V
L
F
A
A
G
G
T
G
E
F
F
S
L
K
P
D
E
I
P
T
I
V
A
A
A
K
E
V
A
-
G
E
T
A
I
V
S
G
C
-
G
Y
-
G
T
E
I
A
V
D
I
A
R
S
V
E
K
V
G
A
D
G
I
L
L
L
P
H
Y
L
I
D
A
P
Q
E
G
L
Y
A
H
I
K
K
V
C
Q
S
V
G
I
G
V
M
V
Y
N
---
R
---
D
N
S
V
L
Q
A
D
T
L
A
R
L
C
D
E
C
P
N
L
V
G
F
K
D
G
T
G
D
I
G
L
V
R
Q
I
T
A
K
M
G
-
D
R
L
M
Y
L
G
G
M
P
T
A
E
L
--
F
A
E
A
-
Y
L
G
A
G
F
T
T
Y
S
S
A
V
F
N
F
V
P
G
L
A
N
E
F
Y
A
A
L
R
A
G
E
R
A
T
C
E
R
I
L
-
V
D
F
F
Y
P
F
M
A
I
R
N
R
A
K
G
Y
A
V
S
A
V
K
A
G
V
R
L
Q
G
F
N
A
G
P
V
R
A
P
L
K
D
L
T
N
E
E
I
G
M
L
E
A
L
I
G
T
-----
102
Fugue
95.63
50%
-131
- C7 -
-
5HWN
8
KDGD_AGRFC
A:
[1-303]
M
D
P
E
Q
I
K
T
A
L
G
S
G
L
L
S
F
P
V
T
H
F
D
A
E
G
R
F
A
A
D
S
Y
R
E
H
V
E
W
L
A
G
Y
K
A
P
V
L
F
A
A
G
G
T
G
E
F
F
S
L
K
P
D
E
I
P
T
I
V
A
A
A
K
E
V
A
-
G
E
T
A
I
V
S
G
C
-
G
Y
-
G
T
E
I
A
V
D
I
A
R
S
V
E
K
V
G
A
D
G
I
L
L
L
P
H
Y
L
I
D
A
P
Q
E
G
L
Y
A
H
I
K
K
V
C
Q
S
V
G
I
G
V
M
V
Y
N
---
R
---
D
N
S
V
L
Q
A
D
T
L
A
R
L
C
D
E
C
P
N
L
V
G
F
K
D
G
T
G
D
I
G
L
V
R
Q
I
T
A
K
M
G
-
D
R
L
M
Y
L
G
G
M
P
T
A
E
L
--
F
A
E
A
-
Y
L
G
A
G
F
T
T
Y
S
S
A
V
F
N
F
V
P
G
L
A
N
E
F
Y
A
A
L
R
A
G
E
R
A
T
C
E
R
I
L
-
V
D
F
F
Y
P
F
M
A
I
R
N
R
A
K
G
Y
A
V
S
A
V
K
A
G
V
R
L
Q
G
F
N
A
G
P
V
R
A
P
L
K
D
L
T
N
E
E
I
G
M
L
E
A
L
I
G
T
H
K
R
K
A
3
PsiBlast_PDB
95.55
50%
-133
- C7 -
-
5HWM
1
KDGD_AGRFC
A:
[1-298]
M
D
P
E
Q
I
K
T
A
L
G
S
G
L
L
S
F
P
V
T
H
F
D
A
E
G
R
F
A
A
D
S
Y
R
E
H
V
E
W
L
A
G
Y
K
A
P
V
L
F
A
A
G
G
T
G
E
F
F
S
L
K
P
D
E
I
P
T
I
V
A
A
A
K
E
V
A
-
G
E
T
A
I
V
S
G
C
-
G
Y
-
G
T
E
I
A
V
D
I
A
R
S
V
E
K
V
G
A
D
G
I
L
L
L
P
H
Y
L
I
D
A
P
Q
E
G
L
Y
A
H
I
K
K
V
C
Q
S
V
G
I
G
V
M
V
Y
N
---
R
---
D
N
S
V
L
Q
A
D
T
L
A
R
L
C
D
E
C
P
N
L
V
G
F
K
D
G
T
G
D
I
G
L
V
R
Q
I
T
A
K
M
G
-
D
R
L
M
Y
L
G
G
M
P
T
A
E
L
--
F
A
E
A
-
Y
L
G
A
G
F
T
T
Y
S
S
A
V
F
N
F
V
P
G
L
A
N
E
F
Y
A
A
L
R
A
G
E
R
A
T
C
E
R
I
L
-
V
D
F
F
Y
P
F
M
A
I
R
N
R
A
K
G
Y
A
V
S
A
V
K
A
G
V
R
L
Q
G
F
N
A
G
P
V
R
A
P
L
K
D
L
T
N
E
E
I
G
M
L
E
A
L
I
G
T
-----
23
PsiBlast_CBE
95.30
50%
-130
- C7 -
-
5HWN
5
KDGD_AGRFC
B:
[1-298]
M
D
P
E
Q
I
K
T
A
L
G
S
G
L
L
S
F
P
V
T
H
F
D
A
E
G
R
F
A
A
D
S
Y
R
E
H
V
E
W
L
A
G
Y
K
A
P
V
L
F
A
A
G
G
T
G
E
F
F
S
L
K
P
D
E
I
P
T
I
V
A
A
A
K
E
V
A
-
G
E
T
A
I
V
S
G
C
-
G
Y
-
G
T
E
I
A
V
D
I
A
R
S
V
E
K
V
G
A
D
G
I
L
L
L
P
H
Y
L
I
D
A
P
Q
E
G
L
Y
A
H
I
K
K
V
C
Q
S
V
G
I
G
V
M
V
Y
N
---
R
---
D
N
S
V
L
Q
A
D
T
L
A
R
L
C
D
E
C
P
N
L
V
G
F
K
D
G
T
G
D
I
G
L
V
R
Q
I
T
A
K
M
G
-
D
R
L
M
Y
L
G
G
M
P
T
A
E
L
--
F
A
E
A
-
Y
L
G
A
G
F
T
T
Y
S
S
A
V
F
N
F
V
P
G
L
A
N
E
F
Y
A
A
L
R
A
G
E
R
A
T
C
E
R
I
L
-
V
D
F
F
Y
P
F
M
A
I
R
N
R
A
K
G
Y
A
V
S
A
V
K
A
G
V
R
L
Q
G
F
N
A
G
P
V
R
A
P
L
K
D
L
T
N
E
E
I
G
M
L
E
A
L
I
G
T
-----
25
PsiBlast_CBE
95.19
50%
-133
- C7 -
-
5HWM
3
KDGD_AGRFC
C:
[1-298]
M
D
P
E
Q
I
K
T
A
L
G
S
G
L
L
S
F
P
V
T
H
F
D
A
E
G
R
F
A
A
D
S
Y
R
E
H
V
E
W
L
A
G
Y
K
A
P
V
L
F
A
A
G
G
T
G
E
F
F
S
L
K
P
D
E
I
P
T
I
V
A
A
A
K
E
V
A
-
G
E
T
A
I
V
S
G
C
-
G
Y
-
G
T
E
I
A
V
D
I
A
R
S
V
E
K
V
G
A
D
G
I
L
L
L
P
H
Y
L
I
D
A
P
Q
E
G
L
Y
A
H
I
K
K
V
C
Q
S
V
G
I
G
V
M
V
Y
N
---
R
---
D
N
S
V
L
Q
A
D
T
L
A
R
L
C
D
E
C
P
N
L
V
G
F
K
D
G
T
G
D
I
G
L
V
R
Q
I
T
A
K
M
G
-
D
R
L
M
Y
L
G
G
M
P
T
A
E
L
--
F
A
E
A
-
Y
L
G
A
G
F
T
T
Y
S
S
A
V
F
N
F
V
P
G
L
A
N
E
F
Y
A
A
L
R
A
G
E
R
A
T
C
E
R
I
L
-
V
D
F
F
Y
P
F
M
A
I
R
N
R
A
K
G
Y
A
V
S
A
V
K
A
G
V
R
L
Q
G
F
N
A
G
P
V
R
A
P
L
K
D
L
T
N
E
E
I
G
M
L
E
A
L
I
G
T
-----
2
PsiBlast_PDB
94.91
50%
-133
- C7 -
-
5HWJ
4
KDGD_AGRFC
A:
[1-298]
M
D
P
E
Q
I
K
T
A
L
G
S
G
L
L
S
F
P
V
T
H
F
D
A
E
G
R
F
A
A
D
S
Y
R
E
H
V
E
W
L
A
G
Y
K
A
P
V
L
F
A
A
G
G
T
G
E
F
F
S
L
K
P
D
E
I
P
T
I
V
A
A
A
K
E
V
A
-
G
E
T
A
I
V
S
G
C
-
G
Y
-
G
T
E
I
A
V
D
I
A
R
S
V
E
K
V
G
A
D
G
I
L
L
L
P
H
Y
L
I
D
A
P
Q
E
G
L
Y
A
H
I
K
K
V
C
Q
S
V
G
I
G
V
M
V
Y
N
---
R
---
D
N
S
V
L
Q
A
D
T
L
A
R
L
C
D
E
C
P
N
L
V
G
F
K
D
G
T
G
D
I
G
L
V
R
Q
I
T
A
K
M
G
-
D
R
L
M
Y
L
G
G
M
P
T
A
E
L
--
F
A
E
A
-
Y
L
G
A
G
F
T
T
Y
S
S
A
V
F
N
F
V
P
G
L
A
N
E
F
Y
A
A
L
R
A
G
E
R
A
T
C
E
R
I
L
-
V
D
F
F
Y
P
F
M
A
I
R
N
R
A
K
G
Y
A
V
S
A
V
K
A
G
V
R
L
Q
G
F
N
A
G
P
V
R
A
P
L
K
D
L
T
N
E
E
I
G
M
L
E
A
L
I
G
T
-----
32
PsiBlast_CBE
94.84
50%
-131
- C7 -
-
4UR8
1
KDGD_AGRFC
B:
[1-298]
M
D
P
E
Q
I
K
T
A
L
G
S
G
L
L
S
F
P
V
T
H
F
D
A
E
G
R
F
A
A
D
S
Y
R
E
H
V
E
W
L
A
G
Y
K
A
P
V
L
F
A
A
G
G
T
G
E
F
F
S
L
K
P
D
E
I
P
T
I
V
A
A
A
K
E
V
A
-
G
E
T
A
I
V
S
G
C
-
G
Y
-
G
T
E
I
A
V
D
I
A
R
S
V
E
K
V
G
A
D
G
I
L
L
L
P
H
Y
L
I
D
A
P
Q
E
G
L
Y
A
H
I
K
K
V
C
Q
S
V
G
I
G
V
M
V
Y
N
---
R
---
D
N
S
V
L
Q
A
D
T
L
A
R
L
C
D
E
C
P
N
L
V
G
F
K
D
G
T
G
D
I
G
L
V
R
Q
I
T
A
K
M
G
-
D
R
L
M
Y
L
G
G
M
P
T
A
E
L
--
F
A
E
A
-
Y
L
G
A
G
F
T
T
Y
S
S
A
V
F
N
F
V
P
G
L
A
N
E
F
Y
A
A
L
R
A
G
E
R
A
T
C
E
R
I
L
-
V
D
F
F
Y
P
F
M
A
I
R
N
R
A
K
G
Y
A
V
S
A
V
K
A
G
V
R
L
Q
G
F
N
A
G
P
V
R
A
P
L
K
D
L
T
N
E
E
I
G
M
L
E
A
L
I
G
T
-----
31
PsiBlast_CBE
94.82
50%
-133
- C7 -
-
4UR8
3
KDGD_AGRFC
C:
[1-298]
M
D
P
E
Q
I
K
T
A
L
G
S
G
L
L
S
F
P
V
T
H
F
D
A
E
G
R
F
A
A
D
S
Y
R
E
H
V
E
W
L
A
G
Y
K
A
P
V
L
F
A
A
G
G
T
G
E
F
F
S
L
K
P
D
E
I
P
T
I
V
A
A
A
K
E
V
A
-
G
E
T
A
I
V
S
G
C
-
G
Y
-
G
T
E
I
A
V
D
I
A
R
S
V
E
K
V
G
A
D
G
I
L
L
L
P
H
Y
L
I
D
A
P
Q
E
G
L
Y
A
H
I
K
K
V
C
Q
S
V
G
I
G
V
M
V
Y
N
---
R
---
D
N
S
V
L
Q
A
D
T
L
A
R
L
C
D
E
C
P
N
L
V
G
F
K
D
G
T
G
D
I
G
L
V
R
Q
I
T
A
K
M
G
-
D
R
L
M
Y
L
G
G
M
P
T
A
E
L
--
F
A
E
A
-
Y
L
G
A
G
F
T
T
Y
S
S
A
V
F
N
F
V
P
G
L
A
N
E
F
Y
A
A
L
R
A
G
E
R
A
T
C
E
R
I
L
-
V
D
F
F
Y
P
F
M
A
I
R
N
R
A
K
G
Y
A
V
S
A
V
K
A
G
V
R
L
Q
G
F
N
A
G
P
V
R
A
P
L
K
D
L
T
N
E
E
I
G
M
L
E
A
L
I
G
T
-----
4
PsiBlast_PDB
94.62
50%
-133
- C7 -
-
5HWN
8
KDGD_AGRFC
A:
[1-298]
M
D
P
E
Q
I
K
T
A
L
G
S
G
L
L
S
F
P
V
T
H
F
D
A
E
G
R
F
A
A
D
S
Y
R
E
H
V
E
W
L
A
G
Y
K
A
P
V
L
F
A
A
G
G
T
G
E
F
F
S
L
K
P
D
E
I
P
T
I
V
A
A
A
K
E
V
A
-
G
E
T
A
I
V
S
G
C
-
G
Y
-
G
T
E
I
A
V
D
I
A
R
S
V
E
K
V
G
A
D
G
I
L
L
L
P
H
Y
L
I
D
A
P
Q
E
G
L
Y
A
H
I
K
K
V
C
Q
S
V
G
I
G
V
M
V
Y
N
---
R
---
D
N
S
V
L
Q
A
D
T
L
A
R
L
C
D
E
C
P
N
L
V
G
F
K
D
G
T
G
D
I
G
L
V
R
Q
I
T
A
K
M
G
-
D
R
L
M
Y
L
G
G
M
P
T
A
E
L
--
F
A
E
A
-
Y
L
G
A
G
F
T
T
Y
S
S
A
V
F
N
F
V
P
G
L
A
N
E
F
Y
A
A
L
R
A
G
E
R
A
T
C
E
R
I
L
-
V
D
F
F
Y
P
F
M
A
I
R
N
R
A
K
G
Y
A
V
S
A
V
K
A
G
V
R
L
Q
G
F
N
A
G
P
V
R
A
P
L
K
D
L
T
N
E
E
I
G
M
L
E
A
L
I
G
T
-----
26
PsiBlast_CBE
94.46
50%
-132
- C7 -
-
5HWM
1
KDGD_AGRFC
B:
[1-298]
M
D
P
E
Q
I
K
T
A
L
G
S
G
L
L
S
F
P
V
T
H
F
D
A
E
G
R
F
A
A
D
S
Y
R
E
H
V
E
W
L
A
G
Y
K
A
P
V
L
F
A
A
G
G
T
G
E
F
F
S
L
K
P
D
E
I
P
T
I
V
A
A
A
K
E
V
A
-
G
E
T
A
I
V
S
G
C
-
G
Y
-
G
T
E
I
A
V
D
I
A
R
S
V
E
K
V
G
A
D
G
I
L
L
L
P
H
Y
L
I
D
A
P
Q
E
G
L
Y
A
H
I
K
K
V
C
Q
S
V
G
I
G
V
M
V
Y
N
---
R
---
D
N
S
V
L
Q
A
D
T
L
A
R
L
C
D
E
C
P
N
L
V
G
F
K
D
G
T
G
D
I
G
L
V
R
Q
I
T
A
K
M
G
-
D
R
L
M
Y
L
G
G
M
P
T
A
E
L
--
F
A
E
A
-
Y
L
G
A
G
F
T
T
Y
S
S
A
V
F
N
F
V
P
G
L
A
N
E
F
Y
A
A
L
R
A
G
E
R
A
T
C
E
R
I
L
-
V
D
F
F
Y
P
F
M
A
I
R
N
R
A
K
G
Y
A
V
S
A
V
K
A
G
V
R
L
Q
G
F
N
A
G
P
V
R
A
P
L
K
D
L
T
N
E
E
I
G
M
L
E
A
L
I
G
T
-----
21
PsiBlast_CBE
94.43
50%
-130
- C7 -
-
5HWN
7
KDGD_AGRFC
D:
[1-298]
M
D
P
E
Q
I
K
T
A
L
G
S
G
L
L
S
F
P
V
T
H
F
D
A
E
G
R
F
A
A
D
S
Y
R
E
H
V
E
W
L
A
G
Y
K
A
P
V
L
F
A
A
G
G
T
G
E
F
F
S
L
K
P
D
E
I
P
T
I
V
A
A
A
K
E
V
A
-
G
E
T
A
I
V
S
G
C
-
G
Y
-
G
T
E
I
A
V
D
I
A
R
S
V
E
K
V
G
A
D
G
I
L
L
L
P
H
Y
L
I
D
A
P
Q
E
G
L
Y
A
H
I
K
K
V
C
Q
S
V
G
I
G
V
M
V
Y
N
---
R
---
D
N
S
V
L
Q
A
D
T
L
A
R
L
C
D
E
C
P
N
L
V
G
F
K
D
G
T
G
D
I
G
L
V
R
Q
I
T
A
K
M
G
-
D
R
L
M
Y
L
G
G
M
P
T
A
E
L
--
F
A
E
A
-
Y
L
G
A
G
F
T
T
Y
S
S
A
V
F
N
F
V
P
G
L
A
N
E
F
Y
A
A
L
R
A
G
E
R
A
T
C
E
R
I
L
-
V
D
F
F
Y
P
F
M
A
I
R
N
R
A
K
G
Y
A
V
S
A
V
K
A
G
V
R
L
Q
G
F
N
A
G
P
V
R
A
P
L
K
D
L
T
N
E
E
I
G
M
L
E
A
L
I
G
T
-----
29
PsiBlast_CBE
94.35
50%
-132
- C7 -
-
5HWJ
4
KDGD_AGRFC
B:
[1-298]
M
D
P
E
Q
I
K
T
A
L
G
S
G
L
L
S
F
P
V
T
H
F
D
A
E
G
R
F
A
A
D
S
Y
R
E
H
V
E
W
L
A
G
Y
K
A
P
V
L
F
A
A
G
G
T
G
E
F
F
S
L
K
P
D
E
I
P
T
I
V
A
A
A
K
E
V
A
-
G
E
T
A
I
V
S
G
C
-
G
Y
-
G
T
E
I
A
V
D
I
A
R
S
V
E
K
V
G
A
D
G
I
L
L
L
P
H
Y
L
I
D
A
P
Q
E
G
L
Y
A
H
I
K
K
V
C
Q
S
V
G
I
G
V
M
V
Y
N
---
R
---
D
N
S
V
L
Q
A
D
T
L
A
R
L
C
D
E
C
P
N
L
V
G
F
K
D
G
T
G
D
I
G
L
V
R
Q
I
T
A
K
M
G
-
D
R
L
M
Y
L
G
G
M
P
T
A
E
L
--
F
A
E
A
-
Y
L
G
A
G
F
T
T
Y
S
S
A
V
F
N
F
V
P
G
L
A
N
E
F
Y
A
A
L
R
A
G
E
R
A
T
C
E
R
I
L
-
V
D
F
F
Y
P
F
M
A
I
R
N
R
A
K
G
Y
A
V
S
A
V
K
A
G
V
R
L
Q
G
F
N
A
G
P
V
R
A
P
L
K
D
L
T
N
E
E
I
G
M
L
E
A
L
I
G
T
-----
27
PsiBlast_CBE
94.10
50%
-130
- C7 -
-
5HWJ
3
KDGD_AGRFC
D:
[1-298]
M
D
P
E
Q
I
K
T
A
L
G
S
G
L
L
S
F
P
V
T
H
F
D
A
E
G
R
F
A
A
D
S
Y
R
E
H
V
E
W
L
A
G
Y
K
A
P
V
L
F
A
A
G
G
T
G
E
F
F
S
L
K
P
D
E
I
P
T
I
V
A
A
A
K
E
V
A
-
G
E
T
A
I
V
S
G
C
-
G
Y
-
G
T
E
I
A
V
D
I
A
R
S
V
E
K
V
G
A
D
G
I
L
L
L
P
H
Y
L
I
D
A
P
Q
E
G
L
Y
A
H
I
K
K
V
C
Q
S
V
G
I
G
V
M
V
Y
N
---
R
---
D
N
S
V
L
Q
A
D
T
L
A
R
L
C
D
E
C
P
N
L
V
G
F
K
D
G
T
G
D
I
G
L
V
R
Q
I
T
A
K
M
G
-
D
R
L
M
Y
L
G
G
M
P
T
A
E
L
--
F
A
E
A
-
Y
L
G
A
G
F
T
T
Y
S
S
A
V
F
N
F
V
P
G
L
A
N
E
F
Y
A
A
L
R
A
G
E
R
A
T
C
E
R
I
L
-
V
D
F
F
Y
P
F
M
A
I
R
N
R
A
K
G
Y
A
V
S
A
V
K
A
G
V
R
L
Q
G
F
N
A
G
P
V
R
A
P
L
K
D
L
T
N
E
E
I
G
M
L
E
A
L
I
G
T
-----
28
PsiBlast_CBE
93.76
50%
-131
- C7 -
-
5HWJ
3
KDGD_AGRFC
C:
[1-298]
M
D
P
E
Q
I
K
T
A
L
G
S
G
L
L
S
F
P
V
T
H
F
D
A
E
G
R
F
A
A
D
S
Y
R
E
H
V
E
W
L
A
G
Y
K
A
P
V
L
F
A
A
G
G
T
G
E
F
F
S
L
K
P
D
E
I
P
T
I
V
A
A
A
K
E
V
A
-
G
E
T
A
I
V
S
G
C
-
G
Y
-
G
T
E
I
A
V
D
I
A
R
S
V
E
K
V
G
A
D
G
I
L
L
L
P
H
Y
L
I
D
A
P
Q
E
G
L
Y
A
H
I
K
K
V
C
Q
S
V
G
I
G
V
M
V
Y
N
---
R
---
D
N
S
V
L
Q
A
D
T
L
A
R
L
C
D
E
C
P
N
L
V
G
F
K
D
G
T
G
D
I
G
L
V
R
Q
I
T
A
K
M
G
-
D
R
L
M
Y
L
G
G
M
P
T
A
E
L
--
F
A
E
A
-
Y
L
G
A
G
F
T
T
Y
S
S
A
V
F
N
F
V
P
G
L
A
N
E
F
Y
A
A
L
R
A
G
E
R
A
T
C
E
R
I
L
-
V
D
F
F
Y
P
F
M
A
I
R
N
R
A
K
G
Y
A
V
S
A
V
K
A
G
V
R
L
Q
G
F
N
A
G
P
V
R
A
P
L
K
D
L
T
N
E
E
I
G
M
L
E
A
L
I
G
T
-----
22
PsiBlast_CBE
93.65
50%
-131
- C7 -
-
5HWN
5
KDGD_AGRFC
C:
[1-298]
M
D
P
E
Q
I
K
T
A
L
G
S
G
L
L
S
F
P
V
T
H
F
D
A
E
G
R
F
A
A
D
S
Y
R
E
H
V
E
W
L
A
G
Y
K
A
P
V
L
F
A
A
G
G
T
G
E
F
F
S
L
K
P
D
E
I
P
T
I
V
A
A
A
K
E
V
A
-
G
E
T
A
I
V
S
G
C
-
G
Y
-
G
T
E
I
A
V
D
I
A
R
S
V
E
K
V
G
A
D
G
I
L
L
L
P
H
Y
L
I
D
A
P
Q
E
G
L
Y
A
H
I
K
K
V
C
Q
S
V
G
I
G
V
M
V
Y
N
---
R
---
D
N
S
V
L
Q
A
D
T
L
A
R
L
C
D
E
C
P
N
L
V
G
F
K
D
G
T
G
D
I
G
L
V
R
Q
I
T
A
K
M
G
-
D
R
L
M
Y
L
G
G
M
P
T
A
E
L
--
F
A
E
A
-
Y
L
G
A
G
F
T
T
Y
S
S
A
V
F
N
F
V
P
G
L
A
N
E
F
Y
A
A
L
R
A
G
E
R
A
T
C
E
R
I
L
-
V
D
F
F
Y
P
F
M
A
I
R
N
R
A
K
G
Y
A
V
S
A
V
K
A
G
V
R
L
Q
G
F
N
A
G
P
V
R
A
P
L
K
D
L
T
N
E
E
I
G
M
L
E
A
L
I
G
T
-----
30
PsiBlast_CBE
93.19
50%
-132
- C7 -
-
4UR8
3
KDGD_AGRFC
D:
[1-298]
M
D
P
E
Q
I
K
T
A
L
G
S
G
L
L
S
F
P
V
T
H
F
D
A
E
G
R
F
A
A
D
S
Y
R
E
H
V
E
W
L
A
G
Y
K
A
P
V
L
F
A
A
G
G
T
G
E
F
F
S
L
K
P
D
E
I
P
T
I
V
A
A
A
K
E
V
A
-
G
E
T
A
I
V
S
G
C
-
G
Y
-
G
T
E
I
A
V
D
I
A
R
S
V
E
K
V
G
A
D
G
I
L
L
L
P
H
Y
L
I
D
A
P
Q
E
G
L
Y
A
H
I
K
K
V
C
Q
S
V
G
I
G
V
M
V
Y
N
---
R
---
D
N
S
V
L
Q
A
D
T
L
A
R
L
C
D
E
C
P
N
L
V
G
F
K
D
G
T
G
D
I
G
L
V
R
Q
I
T
A
K
M
G
-
D
R
L
M
Y
L
G
G
M
P
T
A
E
L
--
F
A
E
A
-
Y
L
G
A
G
F
T
T
Y
S
S
A
V
F
N
F
V
P
G
L
A
N
E
F
Y
A
A
L
R
A
G
E
R
A
T
C
E
R
I
L
-
V
D
F
F
Y
P
F
M
A
I
R
N
R
A
K
G
Y
A
V
S
A
V
K
A
G
V
R
L
Q
G
F
N
A
G
P
V
R
A
P
L
K
D
L
T
N
E
E
I
G
M
L
E
A
L
I
G
T
-----
24
PsiBlast_CBE
93.17
50%
-132
- C7 -
-
5HWM
3
KDGD_AGRFC
D:
[1-298]
M
D
P
E
Q
I
K
T
A
L
G
S
G
L
L
S
F
P
V
T
H
F
D
A
E
G
R
F
A
A
D
S
Y
R
E
H
V
E
W
L
A
G
Y
K
A
P
V
L
F
A
A
G
G
T
G
E
F
F
S
L
K
P
D
E
I
P
T
I
V
A
A
A
K
E
V
A
-
G
E
T
A
I
V
S
G
C
-
G
Y
-
G
T
E
I
A
V
D
I
A
R
S
V
E
K
V
G
A
D
G
I
L
L
L
P
H
Y
L
I
D
A
P
Q
E
G
L
Y
A
H
I
K
K
V
C
Q
S
V
G
I
G
V
M
V
Y
N
---
R
---
D
N
S
V
L
Q
A
D
T
L
A
R
L
C
D
E
C
P
N
L
V
G
F
K
D
G
T
G
D
I
G
L
V
R
Q
I
T
A
K
M
G
-
D
R
L
M
Y
L
G
G
M
P
T
A
E
L
--
F
A
E
A
-
Y
L
G
A
G
F
T
T
Y
S
S
A
V
F
N
F
V
P
G
L
A
N
E
F
Y
A
A
L
R
A
G
E
R
A
T
C
E
R
I
L
-
V
D
F
F
Y
P
F
M
A
I
R
N
R
A
K
G
Y
A
V
S
A
V
K
A
G
V
R
L
Q
G
F
N
A
G
P
V
R
A
P
L
K
D
L
T
N
E
E
I
G
M
L
E
A
L
I
G
T
-----
92
HHSearch
92.91
49%
-109
- C7 -
-
5HWN
5
KDGD_AGRFC
B:
[1-301]
M
D
P
E
Q
I
K
T
A
L
G
S
G
L
L
S
F
P
V
T
H
F
D
A
E
G
R
F
A
A
D
S
Y
R
E
H
V
E
W
L
A
G
Y
K
A
P
V
L
F
A
A
G
G
T
G
E
F
F
S
L
K
P
D
E
I
P
T
I
V
A
A
A
K
E
V
A
-
G
E
T
A
I
V
S
G
C
-
G
Y
-
G
T
E
I
A
V
D
I
A
R
S
V
E
K
V
G
A
D
G
I
L
L
L
P
H
Y
L
I
D
A
P
Q
E
G
L
Y
A
H
I
K
K
V
C
Q
S
V
G
I
G
V
M
V
Y
N
---
R
---
D
N
S
V
L
Q
A
D
T
L
A
R
L
C
D
E
C
P
N
L
V
G
F
K
D
G
T
G
D
I
G
L
V
R
Q
I
T
A
K
M
G
-
D
R
L
M
Y
L
G
G
M
---
P
T
AE
L
F
A
E
A
Y
L
G
A
G
F
T
T
Y
S
S
A
V
F
N
F
V
P
G
L
A
N
E
F
Y
A
A
L
R
A
G
E
R
A
T
C
E
R
I
L
V
D
F
F
-
Y
P
F
M
A
I
R
N
R
A
K
G
Y
A
V
S
A
V
K
A
G
V
R
L
Q
G
F
N
A
G
P
V
R
A
P
L
K
D
L
T
N
E
E
I
G
M
L
E
A
L
I
G
T
H
K
R
--
93
HHSearch
91.56
49%
-107
- C7 -
-
5HWN
7
KDGD_AGRFC
D:
[1-301]
M
D
P
E
Q
I
K
T
A
L
G
S
G
L
L
S
F
P
V
T
H
F
D
A
E
G
R
F
A
A
D
S
Y
R
E
H
V
E
W
L
A
G
Y
K
A
P
V
L
F
A
A
G
G
T
G
E
F
F
S
L
K
P
D
E
I
P
T
I
V
A
A
A
K
E
V
A
-
G
E
T
A
I
V
S
G
C
-
G
Y
-
G
T
E
I
A
V
D
I
A
R
S
V
E
K
V
G
A
D
G
I
L
L
L
P
H
Y
L
I
D
A
P
Q
E
G
L
Y
A
H
I
K
K
V
C
Q
S
V
G
I
G
V
M
V
Y
N
---
R
---
D
N
S
V
L
Q
A
D
T
L
A
R
L
C
D
E
C
P
N
L
V
G
F
K
D
G
T
G
D
I
G
L
V
R
Q
I
T
A
K
M
G
-
D
R
L
M
Y
L
G
G
M
---
P
T
AE
L
F
A
E
A
Y
L
G
A
G
F
T
T
Y
S
S
A
V
F
N
F
V
P
G
L
A
N
E
F
Y
A
A
L
R
A
G
E
R
A
T
C
E
R
I
L
V
D
F
F
-
Y
P
F
M
A
I
R
N
R
A
K
G
Y
A
V
S
A
V
K
A
G
V
R
L
Q
G
F
N
A
G
P
V
R
A
P
L
K
D
L
T
N
E
E
I
G
M
L
E
A
L
I
G
T
H
K
R
--
89
HHSearch
73.22
26%
-56
- C7 -
-
3QZE
-
DAPA_PSEAE
C:
[24-312]
----------
I
A
G
S
M
V
A
L
V
T
P
F
D
A
Q
G
R
L
D
W
D
S
L
A
K
L
V
D
F
H
L
Q
E
G
T
N
A
I
V
A
V
G
T
T
G
E
S
A
T
L
D
V
E
E
H
I
Q
V
I
R
R
V
V
D
Q
V
K
G
R
I
P
V
I
A
G
T
G
A
N
-
S
T
R
E
A
V
A
L
T
E
A
A
K
S
G
G
A
D
A
C
L
L
V
T
P
Y
Y
N
K
P
T
Q
E
G
M
Y
Q
H
F
R
H
I
A
E
A
V
A
I
P
Q
I
L
Y
N
---
V
PGR
T
S
C
D
M
L
P
E
T
V
E
R
L
S
K
-
V
P
N
I
I
G
I
K
E
A
T
G
D
L
Q
R
A
K
E
V
I
E
R
V
G
-
K
D
F
L
V
Y
S
G
D
---
D
A
--
T
A
V
E
-
L
M
L
L
G
G
K
G
N
I
S
V
T
A
N
V
A
P
R
A
M
S
D
L
C
A
A
A
M
R
G
D
A
A
A
A
R
A
I
N
-
D
R
L
-
M
P
L
H
K
A
L
F
I
--
E
S
N
P
I
P
V
K
W
A
L
H
E
M
G
L
I
P
E
G
I
R
L
P
L
T
W
L
S
P
R
C
H
E
P
L
R
Q
A
M
R
Q
T
G
V
--
68
PsiBlast_CBE
49.21
32%
-43
- C7 -
-
3S8H
1
DAPA_PSEAE
A:
[10-191]
------------------
V
T
P
F
D
A
Q
G
R
L
D
W
D
S
L
A
K
L
V
D
F
H
L
Q
D
G
T
N
A
I
V
A
V
G
T
T
G
E
S
A
T
L
D
V
E
E
H
I
Q
V
V
R
R
V
V
D
Q
V
K
G
R
I
P
V
I
A
G
T
-
G
A
N
S
T
R
E
A
V
A
L
T
E
A
A
K
S
G
G
A
D
A
C
L
L
V
T
P
Y
Y
N
K
P
T
Q
E
G
M
Y
Q
H
F
R
H
I
A
E
A
V
A
I
P
Q
I
L
Y
N
V
PG
R
---
T
S
C
D
M
L
P
E
T
V
E
R
L
S
K
V
-
P
N
I
I
G
I
K
E
A
T
G
D
L
Q
R
A
K
E
V
I
E
R
V
G
K
D
F
L
V
Y
S
G
D
D
A
T
A
----------------------------------------------------------------------------------------------------------------