@TOME V2.3
(Mar 2018)
Ref.
-
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Doc.
Global output mode :
Sort entries by :
Atome Result
Tools Result
PDB occurence
Core Structure Cluster
Sequence Color type :
Secondary Structure
Hydrophobicity
Disulfide Bonds
TCoffee Identity Score
Uniprot annotation
Core Structure Cluster
Contacts with Ligands
Show alignment :
Atome selection
All alignments
Only Template with Ligand
Column output:
Score:
Atome Rank Value
Tools Score
Hide column
Alignment:
Sequence Identity (%)
Tcoffee Alignment Score
Hide column
3D Common Core:
Tito PKB Score
Verify3D Score
QMean Score
Hide column
Structural Clustering:
Cluster Num
3D-Jury Struct. Score
Hide column
Modeller Result :
Model Rank
QMean Score
Dfire Score
Dope Score
Errat Score
Verify3D Score
Modeller Score
Hide column
Complexes Modeling
Show Ligands of Templates
Complexes Affinity Score
Main Binding Site Identity
Hide column
Templates Information:
Uniprot entry
Cath class
Scop class
Smart class
Prosite class
Pfam class
EC Number
Taxonomy
Experiment Method
Hide column
Sequence & Result Tab:
PDB Template Sequence
Complexes Tab
Values color: [
Good
|
Correct
|
Middling
|
Bad
]
Sequence color :
Mutated
Helix
Strand
Conserved
Query sequence : B0VPZ8: (2017-11-24 )
MSAAPRIGILGAGGRMGRTLIQAVQQAGYQLAAAVERPESSLVGTDAGELAGIGSVGVKVSGSLADVLKDCDVIIDFTAPAATAQHLKLCREAGVAMVIGTTGMSDEQKAELDEAATHIPVVYAANYSVGVNVSIKLLELAAKVFGDTVDIEVIEAHHRHKVDAPSGTALMMGEAIADTLGRNLKEVAVYGREGHTGPRDRQTIGFETIRGGDIVGEHTVMFIGEGERVEVTHKATNRMNFAAGAVRAAAWVVGREARKYDMKDVLGLNDVQV
Atome Classification :
(22 SA)
.........10........20..-....--.--.30........40........50.---.--.--.--....60........70........80........90........100.......110.......120.......130.......140.......150.......160.......170.......180...-....190........200.......210.......220.......230.......240.......250.......260.......270.
(Atome)
(Ident)
(Tito)
(Num)
(QMean)
(Ligand)
(Uniprot)
MSAAP
R
I
G
I
LGAGG
R
M
G
R
T
L
I
Q
A
-
V
Q
QA--G--
Y
Q
L
A
A
A
VERPESSLVGTD
A
G
E
LAG---I--G--S--V
G
V
K
VS
G
S
L
A
D
V
L
KDC
D
V
I
I
DFTAP
A
A
T
A
Q
H
L
K
L
C
R
EAG
V
A
M
V
I
GTTGMS
D
E
Q
K
A
E
L
D
E
AATHI
P
V
V
Y
AAN
Y
S
V
G
V
N
V
S
I
K
L
L
E
L
A
A
K
VFGDTV
D
I
E
V
I
E
AHHRHKVDAPSGT
A
L
M
M
G
E
A
I
A
D
T
LGR
N
L
K
-
E
V
A
V
Y-GREGHTGPRDR
Q
T
IG
F
E
T
IRGG
D
I
VG
E
H
T
V
M
F
IGEG
E
R
V
E
V
T
HKATNRMNF
A
A
G
A
V
R
A
A
A
W
V
VGREARKY
D
M
K
D
VLGLNDVQV
21
PsiBlast_CBE
78.70
63%
-29
- C1 -
-
4YWJ
3
DAPB_PSEAE
B:
[11-276]
-----
R
I
A
V
V
G
A
A
G
R
M
G
K
N
L
I
E
A
-
V
Q
Q
T
--
G
GA
A
G
L
T
A
A
V
D
R
P
D
S
T
L
V
G
A
D
A
G
E
L
A
G
---
L
--
G
--
R
--
I
G
V
P
L
S
G
D
L
G
K
V
C
E
E
F
D
V
L
I
D
F
T
H
P
S
V
T
L
K
N
I
E
Q
C
R
K
A
R
R
A
M
V
I
G
T
T
G
F
S
A
D
E
K
L
L
L
A
E
A
A
K
D
I
P
I
V
F
A
A
N
F
S
V
G
V
N
L
C
L
K
L
L
D
T
A
A
R
V
L
G
D
E
V
D
I
E
I
I
E
A
H
H
R
H
K
V
D
A
P
S
G
T
A
L
R
M
G
E
V
V
A
Q
A
L
G
R
D
L
Q
-
E
V
A
V
Y
-
G
R
E
G
Q
T
G
A
R
A
R
E
T
I
G
F
A
T
V
R
A
G
D
V
V
G
D
H
T
V
L
F
A
A
E
G
E
R
V
E
I
T
H
K
A
S
S
R
M
T
F
A
R
G
A
V
R
A
A
L
W
L
E
G
K
E
N
G
L
Y
D
M
Q
D
V
L
G
L
R
----
36
HHSearch
78.53
64%
-34
- C1 -
-
4YWJ
3
DAPB_PSEAE
A:
[9-275]
---
M
R
R
I
A
V
V
G
A
A
G
R
M
G
K
N
L
I
E
A
-
V
Q
Q
T
GG
A
--
A
G
L
T
A
A
V
D
R
P
D
S
T
L
V
G
A
D
A
G
E
L
A
G
---
L
--
G
--
R
IG
V
P
--
L
S
G
D
L
G
K
V
C
E
E
F
D
V
L
I
D
F
T
H
P
S
V
T
L
K
N
I
E
Q
C
R
K
A
R
R
A
M
V
I
G
T
T
G
F
S
A
D
E
K
L
L
L
A
E
A
A
K
D
I
P
I
V
F
A
A
N
F
S
V
G
V
N
L
C
L
K
L
L
D
T
A
A
R
V
L
G
D
E
V
D
I
E
I
I
E
A
H
H
R
H
K
V
D
A
P
S
G
T
A
L
R
M
G
E
V
V
A
Q
A
L
G
R
D
L
Q
-
E
V
A
V
Y
-
G
R
E
G
Q
T
G
A
R
A
R
E
T
I
G
F
A
T
V
R
A
G
D
V
V
G
D
H
T
V
L
F
A
A
E
G
E
R
V
E
I
T
H
K
A
S
S
R
M
T
F
A
R
G
A
V
R
A
A
L
W
L
E
G
K
E
N
G
L
Y
D
M
Q
D
V
L
G
L
-----
1
PsiBlast_PDB
77.46
63%
-27
- C1 -
-
4YWJ
3
DAPB_PSEAE
A:
[11-276]
-----
R
I
A
V
V
G
A
A
G
R
M
G
K
N
L
I
E
A
-
V
Q
Q
T
--
G
GA
A
G
L
T
A
A
V
D
R
P
D
S
T
L
V
G
A
D
A
G
E
L
A
G
---
L
--
G
--
R
--
I
G
V
P
L
S
G
D
L
G
K
V
C
E
E
F
D
V
L
I
D
F
T
H
P
S
V
T
L
K
N
I
E
Q
C
R
K
A
R
R
A
M
V
I
G
T
T
G
F
S
A
D
E
K
L
L
L
A
E
A
A
K
D
I
P
I
V
F
A
A
N
F
S
V
G
V
N
L
C
L
K
L
L
D
T
A
A
R
V
L
G
D
E
V
D
I
E
I
I
E
A
H
H
R
H
K
V
D
A
P
S
G
T
A
L
R
M
G
E
V
V
A
Q
A
L
G
R
D
L
Q
-
E
V
A
V
Y
-
G
R
E
G
Q
T
G
A
R
A
R
E
T
I
G
F
A
T
V
R
A
G
D
V
V
G
D
H
T
V
L
F
A
A
E
G
E
R
V
E
I
T
H
K
A
S
S
R
M
T
F
A
R
G
A
V
R
A
A
L
W
L
E
G
K
E
N
G
L
Y
D
M
Q
D
V
L
G
L
R
----
45
HHSearch
76.58
61%
-42
* C1 *
-
1DRU
1
DAPB_ECOLI
A:
[4-271]
--
A
N
I
R
V
A
I
A
G
A
G
G
R
M
G
R
Q
L
I
Q
A
-
A
L
A
L
E-
G
--
V
Q
L
G
A
A
L
E
R
E
G
S
S
L
L
G
S
D
A
G
E
L
A
G
---
A
GK
T
--
G
--
V
T
--
V
Q
S
S
L
D
A
V
K
D
D
F
D
V
F
I
D
F
T
R
P
E
G
T
L
N
H
L
A
F
C
R
Q
H
G
K
G
M
V
I
G
T
T
G
F
D
E
A
G
K
Q
A
I
R
D
A
A
A
D
I
A
I
V
F
A
A
N
F
S
V
G
V
N
V
M
L
K
L
L
E
K
A
A
K
V
M
G
D
Y
T
D
I
E
I
I
E
A
H
H
R
H
K
V
D
A
P
S
G
T
A
L
A
M
G
E
A
I
A
H
A
L
D
K
D
L
K
D
C
A
V
Y
S
--
R
E
G
H
T
G
E
R
V
P
G
T
I
G
F
A
T
V
R
A
G
D
I
V
G
E
H
T
A
M
F
A
D
I
G
E
R
L
E
I
T
H
K
A
S
S
R
M
T
F
A
N
G
A
V
R
S
A
L
W
L
S
G
K
E
S
G
L
F
D
M
R
D
V
L
D
L
N
----
46
HHSearch
76.24
61%
-43
- C1 -
-
1DRW
1
DAPB_ECOLI
A:
[2-271]
H
D
A
N
I
R
V
A
I
A
G
A
G
G
R
M
G
R
Q
L
I
Q
A
-
A
L
A
L
E-
G
--
V
Q
L
G
A
A
L
E
R
E
G
S
S
L
L
G
S
D
A
G
E
L
A
G
---
A
GK
T
--
G
--
V
T
--
V
Q
S
S
L
D
A
V
K
D
D
F
D
V
F
I
D
F
T
R
P
E
G
T
L
N
H
L
A
F
C
R
Q
H
G
K
G
M
V
I
G
T
T
G
F
D
E
A
G
K
Q
A
I
R
D
A
A
A
D
I
A
I
V
F
A
A
N
F
S
V
G
V
N
V
M
L
K
L
L
E
K
A
A
K
V
M
G
D
Y
T
D
I
E
I
I
E
A
H
H
R
H
K
V
D
A
P
S
G
T
A
L
A
M
G
E
A
I
A
H
A
L
D
K
D
L
K
D
C
A
V
Y
S
--
R
E
G
H
T
G
E
R
V
P
G
T
I
G
F
A
T
V
R
A
G
D
I
V
G
E
H
T
A
M
F
A
D
I
G
E
R
L
E
I
T
H
K
A
S
S
R
M
T
F
A
N
G
A
V
R
S
A
L
W
L
S
G
K
E
S
G
L
F
D
M
R
D
V
L
D
L
N
----
6
PsiBlast_PDB
75.91
62%
-28
- C1 -
-
1DRW
1
DAPB_ECOLI
A:
[7-273]
-----
R
V
A
I
A
G
A
G
G
R
M
G
R
Q
L
I
Q
A
A
L
A
L
E
--
G
--
V
Q
L
G
A
A
L
E
R
E
G
S
S
L
L
G
S
D
A
G
E
L
A
G
---
A
--
G
--
K
--
T
G
V
T
V
Q
S
S
L
D
A
V
K
D
D
F
D
V
F
I
D
F
T
R
P
E
G
T
L
N
H
L
A
F
C
R
Q
H
G
K
G
M
V
I
G
T
T
G
F
D
E
A
G
K
Q
A
I
R
D
A
A
A
D
I
A
I
V
F
A
A
N
F
S
V
G
V
N
V
M
L
K
L
L
E
K
A
A
K
V
M
G
D
Y
T
D
I
E
I
I
E
A
H
H
R
H
K
V
D
A
P
S
G
T
A
L
A
M
G
E
A
I
A
H
A
L
D
K
D
L
K
-
D
C
A
V
Y
-
S
R
E
G
H
T
G
E
R
V
P
G
T
I
G
F
A
T
V
R
A
G
D
I
V
G
E
H
T
A
M
F
A
D
I
G
E
R
L
E
I
T
H
K
A
S
S
R
M
T
F
A
N
G
A
V
R
S
A
L
W
L
S
G
K
E
S
G
L
F
D
M
R
D
V
L
D
L
N
N
L
--
4
PsiBlast_PDB
75.26
62%
-26
- C1 -
-
1DRU
1
DAPB_ECOLI
A:
[7-273]
-----
R
V
A
I
A
G
A
G
G
R
M
G
R
Q
L
I
Q
A
A
L
A
L
E
--
G
--
V
Q
L
G
A
A
L
E
R
E
G
S
S
L
L
G
S
D
A
G
E
L
A
G
---
A
--
G
--
K
--
T
G
V
T
V
Q
S
S
L
D
A
V
K
D
D
F
D
V
F
I
D
F
T
R
P
E
G
T
L
N
H
L
A
F
C
R
Q
H
G
K
G
M
V
I
G
T
T
G
F
D
E
A
G
K
Q
A
I
R
D
A
A
A
D
I
A
I
V
F
A
A
N
F
S
V
G
V
N
V
M
L
K
L
L
E
K
A
A
K
V
M
G
D
Y
T
D
I
E
I
I
E
A
H
H
R
H
K
V
D
A
P
S
G
T
A
L
A
M
G
E
A
I
A
H
A
L
D
K
D
L
K
-
D
C
A
V
Y
-
S
R
E
G
H
T
G
E
R
V
P
G
T
I
G
F
A
T
V
R
A
G
D
I
V
G
E
H
T
A
M
F
A
D
I
G
E
R
L
E
I
T
H
K
A
S
S
R
M
T
F
A
N
G
A
V
R
S
A
L
W
L
S
G
K
E
S
G
L
F
D
M
R
D
V
L
D
L
N
N
L
--
3
PsiBlast_PDB
74.98
62%
-26
- C1 -
-
1DIH
1
DAPB_ECOLI
A:
[7-273]
-----
R
V
A
I
A
G
A
G
G
R
M
G
R
Q
L
I
Q
A
A
L
A
L
E
--
G
--
V
Q
L
G
A
A
L
E
R
E
G
S
S
L
L
G
S
D
A
G
E
L
A
G
---
A
--
G
--
K
--
T
G
V
T
V
Q
S
S
L
D
A
V
K
D
D
F
D
V
F
I
D
F
T
R
P
E
G
T
L
N
H
L
A
F
C
R
Q
H
G
K
G
M
V
I
G
T
T
G
F
D
E
A
G
K
Q
A
I
R
D
A
A
A
D
I
A
I
V
F
A
A
N
F
S
V
G
V
N
V
M
L
K
L
L
E
K
A
A
K
V
M
G
D
Y
T
D
I
E
I
I
E
A
H
H
R
H
K
V
D
A
P
S
G
T
A
L
A
M
G
E
A
I
A
H
A
L
D
K
D
L
K
-
D
C
A
V
Y
-
S
R
E
G
H
T
G
E
R
V
P
G
T
I
G
F
A
T
V
R
A
G
D
I
V
G
E
H
T
A
M
F
A
D
I
G
E
R
L
E
I
T
H
K
A
S
S
R
M
T
F
A
N
G
A
V
R
S
A
L
W
L
S
G
K
E
S
G
L
F
D
M
R
D
V
L
D
L
N
N
L
--
2
PsiBlast_PDB
74.52
62%
-26
- C1 -
-
1ARZ
-
DAPB_ECOLI
A:
[7-273]
-----
R
V
A
I
A
G
A
G
G
R
M
G
R
Q
L
I
Q
A
A
L
A
L
E
--
G
--
V
Q
L
G
A
A
L
E
R
E
G
S
S
L
L
G
S
D
A
G
E
L
A
G
---
A
--
G
--
K
--
T
G
V
T
V
Q
S
S
L
D
A
V
K
D
D
F
D
V
F
I
D
F
T
R
P
E
G
T
L
N
H
L
A
F
C
R
Q
H
G
K
G
M
V
I
G
T
T
G
F
D
E
A
G
K
Q
A
I
R
D
A
A
A
D
I
A
I
V
F
A
A
N
F
S
V
G
V
N
V
M
L
K
L
L
E
K
A
A
K
V
M
G
D
Y
T
D
I
E
I
I
E
A
H
H
R
H
K
V
D
A
P
S
G
T
A
L
A
M
G
E
A
I
A
H
A
L
D
K
D
L
K
-
D
C
A
V
Y
-
S
R
E
G
H
T
G
E
R
V
P
G
T
I
G
F
A
T
V
R
A
G
D
I
V
G
E
H
T
A
M
F
A
D
I
G
E
R
L
E
I
T
H
K
A
S
S
R
M
T
F
A
N
G
A
V
R
S
A
L
W
L
S
G
K
E
S
G
L
F
D
M
R
D
V
L
D
L
N
N
L
--
24
PsiBlast_CBE
74.27
62%
-25
- C1 -
-
1ARZ
2
DAPB_ECOLI
B:
[7-273]
-----
R
V
A
I
A
G
A
G
G
R
M
G
R
Q
L
I
Q
A
A
L
A
L
E
--
G
--
V
Q
L
G
A
A
L
E
R
E
G
S
S
L
L
G
S
D
A
G
E
L
A
G
---
A
--
G
--
K
--
T
G
V
T
V
Q
S
S
L
D
A
V
K
D
D
F
D
V
F
I
D
F
T
R
P
E
G
T
L
N
H
L
A
F
C
R
Q
H
G
K
G
M
V
I
G
T
T
G
F
D
E
A
G
K
Q
A
I
R
D
A
A
A
D
I
A
I
V
F
A
A
N
F
S
V
G
V
N
V
M
L
K
L
L
E
K
A
A
K
V
M
G
D
Y
T
D
I
E
I
I
E
A
H
H
R
H
K
V
D
A
P
S
G
T
A
L
A
M
G
E
A
I
A
H
A
L
D
K
D
L
K
-
D
C
A
V
Y
-
S
R
E
G
H
T
G
E
R
V
P
G
T
I
G
F
A
T
V
R
A
G
D
I
V
G
E
H
T
A
M
F
A
D
I
G
E
R
L
E
I
T
H
K
A
S
S
R
M
T
F
A
N
G
A
V
R
S
A
L
W
L
S
G
K
E
S
G
L
F
D
M
R
D
V
L
D
L
N
N
L
--
22
PsiBlast_CBE
73.94
62%
-27
- C1 -
-
1ARZ
2
DAPB_ECOLI
D:
[7-273]
-----
R
V
A
I
A
G
A
G
G
R
M
G
R
Q
L
I
Q
A
A
L
A
L
E
--
G
--
V
Q
L
G
A
A
L
E
R
E
G
S
S
L
L
G
S
D
A
G
E
L
A
G
---
A
--
G
--
K
--
T
G
V
T
V
Q
S
S
L
D
A
V
K
D
D
F
D
V
F
I
D
F
T
R
P
E
G
T
L
N
H
L
A
F
C
R
Q
H
G
K
G
M
V
I
G
T
T
G
F
D
E
A
G
K
Q
A
I
R
D
A
A
A
D
I
A
I
V
F
A
A
N
F
S
V
G
V
N
V
M
L
K
L
L
E
K
A
A
K
V
M
G
D
Y
T
D
I
E
I
I
E
A
H
H
R
H
K
V
D
A
P
S
G
T
A
L
A
M
G
E
A
I
A
H
A
L
D
K
D
L
K
-
D
C
A
V
Y
-
S
R
E
G
H
T
G
E
R
V
P
G
T
I
G
F
A
T
V
R
A
G
D
I
V
G
E
H
T
A
M
F
A
D
I
G
E
R
L
E
I
T
H
K
A
S
S
R
M
T
F
A
N
G
A
V
R
S
A
L
W
L
S
G
K
E
S
G
L
F
D
M
R
D
V
L
D
L
N
N
L
--
43
HHSearch
73.71
54%
-58
- C1 -
-
4F3Y
-
DAPB_BURTA
A:
[6-271]
--
S
S
M
K
I
A
I
A
G
A
S
G
R
M
G
R
M
L
I
E
A
-
V
L
A
A
P-
D
--
A
T
L
V
G
A
L
D
R
T
G
S
P
Q
L
G
Q
D
A
G
A
F
L
G
KQT
G
--------
V
A
--
L
T
D
D
I
E
R
V
C
A
E
A
D
Y
L
I
D
F
T
L
P
E
G
T
L
V
H
L
D
A
A
L
R
H
D
V
K
L
V
I
G
T
T
G
F
S
E
P
Q
K
A
Q
L
R
A
A
G
E
K
I
A
L
V
F
S
A
N
M
S
V
G
V
N
V
T
M
K
L
L
E
F
A
A
K
Q
F
A
Q
G
Y
D
I
E
I
I
E
A
H
H
R
H
K
V
D
A
P
S
G
T
A
L
M
M
G
E
T
I
A
A
A
T
G
R
S
-
L
-
D
D
C
A
V
Y
G
R
H
G
V
T
G
E
R
D
P
S
T
I
G
F
S
A
I
R
G
G
D
I
V
G
D
H
T
V
L
F
A
G
I
G
E
R
I
E
I
T
H
K
S
A
S
R
V
S
Y
A
Q
G
A
L
R
A
A
R
F
L
A
G
R
D
A
G
F
F
D
M
Q
D
V
L
G
L
-----
23
PsiBlast_CBE
73.58
62%
-25
- C1 -
-
1ARZ
2
DAPB_ECOLI
C:
[7-273]
-----
R
V
A
I
A
G
A
G
G
R
M
G
R
Q
L
I
Q
A
A
L
A
L
E
--
G
--
V
Q
L
G
A
A
L
E
R
E
G
S
S
L
L
G
S
D
A
G
E
L
A
G
---
A
--
G
--
K
--
T
G
V
T
V
Q
S
S
L
D
A
V
K
D
D
F
D
V
F
I
D
F
T
R
P
E
G
T
L
N
H
L
A
F
C
R
Q
H
G
K
G
M
V
I
G
T
T
G
F
D
E
A
G
K
Q
A
I
R
D
A
A
A
D
I
A
I
V
F
A
A
N
F
S
V
G
V
N
V
M
L
K
L
L
E
K
A
A
K
V
M
G
D
Y
T
D
I
E
I
I
E
A
H
H
R
H
K
V
D
A
P
S
G
T
A
L
A
M
G
E
A
I
A
H
A
L
D
K
D
L
K
-
D
C
A
V
Y
-
S
R
E
G
H
T
G
E
R
V
P
G
T
I
G
F
A
T
V
R
A
G
D
I
V
G
E
H
T
A
M
F
A
D
I
G
E
R
L
E
I
T
H
K
A
S
S
R
M
T
F
A
N
G
A
V
R
S
A
L
W
L
S
G
K
E
S
G
L
F
D
M
R
D
V
L
D
L
N
N
L
--
44
HHSearch
73.55
54%
-59
- C1 -
-
4F3Y
-
DAPB_BURTA
B:
[6-271]
--
S
S
M
K
I
A
I
A
G
A
S
G
R
M
G
R
M
L
I
E
A
-
V
L
A
A
P-
D
--
A
T
L
V
G
A
L
D
R
T
G
S
P
Q
L
G
Q
D
A
G
A
F
L
G
KQT
G
--------
V
A
--
L
T
D
D
I
E
R
V
C
A
E
A
D
Y
L
I
D
F
T
L
P
E
G
T
L
V
H
L
D
A
A
L
R
H
D
V
K
L
V
I
G
T
T
G
F
S
--
Q
K
A
Q
L
R
A
A
G
E
K
I
A
L
V
F
S
A
N
M
S
V
G
V
N
V
T
M
K
L
L
E
F
A
A
K
Q
F
A
Q
G
Y
D
I
E
I
I
E
A
H
H
R
H
K
V
D
A
P
S
G
T
A
L
M
M
G
E
T
I
A
A
A
T
G
R
S
-
L
-
D
D
C
A
V
Y
G
R
H
G
V
T
G
E
R
D
P
S
T
I
G
F
S
A
I
R
G
G
D
I
V
G
D
H
T
V
L
F
A
G
I
G
E
R
I
E
I
T
H
K
S
A
S
R
V
S
Y
A
Q
G
A
L
R
A
A
R
F
L
A
G
R
D
A
G
F
F
D
M
Q
D
V
L
G
L
-----
5
PsiBlast_PDB
73.55
62%
-20
- C1 -
-
1DRV
1
DAPB_ECOLI
A:
[7-273]
-----
R
V
A
I
A
G
A
G
G
R
M
G
R
Q
L
I
Q
A
A
L
A
L
E
--
G
--
V
Q
L
G
A
A
L
E
R
E
G
S
S
L
L
G
S
D
A
G
E
L
A
G
---
A
--
G
--
K
--
T
G
V
T
V
Q
S
S
L
D
A
V
K
D
D
F
D
V
F
I
D
F
T
R
P
E
G
T
L
N
H
L
A
F
C
R
Q
H
G
K
G
M
V
I
G
T
T
G
F
D
E
A
G
K
Q
A
I
R
D
A
A
A
D
I
A
I
V
F
A
A
N
F
S
V
G
V
N
V
M
L
K
L
L
E
K
A
A
K
V
M
G
D
Y
T
D
I
E
I
I
E
A
H
H
R
H
K
V
D
A
P
S
G
T
A
L
A
M
G
E
A
I
A
H
A
L
D
K
D
L
K
-
D
C
A
V
Y
-
S
R
E
G
H
T
G
E
R
V
P
G
T
I
G
F
A
T
V
R
A
G
D
I
V
G
E
H
T
A
M
F
A
D
I
G
E
R
L
E
I
T
H
K
A
S
S
R
M
T
F
A
N
G
A
V
R
S
A
L
W
L
S
G
K
E
S
G
L
F
D
M
R
D
V
L
D
L
N
N
L
--
7
PsiBlast_PDB
73.04
55%
-44
- C1 -
-
4F3Y
-
DAPB_BURTA
A:
[9-272]
-----
K
I
A
I
A
G
A
S
G
R
M
G
R
M
L
I
E
A
-
V
L
A
A
P-
D
--
A
T
L
V
G
A
L
D
R
T
G
S
P
Q
L
G
Q
D
A
G
A
F
L
G
------
K
--
Q
--
T
G
V
A
L
T
D
D
I
E
R
V
C
A
E
A
D
Y
L
I
D
F
T
L
P
E
G
T
L
V
H
L
D
A
A
L
R
H
D
V
K
L
V
I
G
T
T
G
F
S
E
P
Q
K
A
Q
L
R
A
A
G
E
K
I
A
L
V
F
S
A
N
M
S
V
G
V
N
V
T
M
K
L
L
E
F
A
A
K
Q
F
A
Q
G
Y
D
I
E
I
I
E
A
H
H
R
H
K
V
D
A
P
S
G
T
A
L
M
M
G
E
T
I
A
A
A
T
G
R
S
L
D
-
D
C
A
V
Y
-
G
R
H
G
V
T
G
E
R
D
P
S
T
I
G
F
S
A
I
R
G
G
D
I
V
G
D
H
T
V
L
F
A
G
I
G
E
R
I
E
I
T
H
K
S
A
S
R
V
S
Y
A
Q
G
A
L
R
A
A
R
F
L
A
G
R
D
A
G
F
F
D
M
Q
D
V
L
G
L
R
----
10
PsiBlast_PDB
70.05
32%
-138
- C1 -
-
3QY9
1
DAPB_STAAC
A:
[3-243]
---
S
M
K
I
L
L
I
G
Y
G
A
-
M
N
Q
R
V
A
R
L
-
A
E
E
K
--
G
--
H
E
I
V
G
V
I
E
N
T
P
K
------------------------
T
P
Y
Q
Q
Y
Q
H
I
A
D
V
-
K
G
A
D
V
A
I
D
F
S
N
P
N
L
L
F
P
L
L
D
--
E
D
F
H
L
P
L
V
V
A
T
T
G
E
K
E
K
L
L
N
K
L
D
E
L
S
Q
N
M
P
V
F
F
S
A
N
M
S
Y
G
V
H
A
L
T
K
I
L
A
A
A
V
P
L
L
D
D
-
F
D
I
E
L
T
E
A
H
H
N
K
K
V
D
A
P
S
G
T
L
E
K
L
Y
D
V
I
V
-
S
L
K
E
N
V
---
T
P
V
Y
-
D
R
H
E
L
N
E
K
R
Q
P
Q
D
I
G
I
H
S
I
R
G
G
T
I
V
G
E
H
E
V
L
F
A
G
T
D
E
T
I
Q
I
T
H
R
A
Q
S
K
D
I
F
A
N
G
A
I
Q
A
A
E
R
L
V
N
K
P
N
G
F
Y
T
F
D
N
L
--------
59
Fugue
69.69
34%
-135
- C1 -
-
3QY9
1
DAPB_STAAC
A:
[3-243]
---
S
M
K
I
L
L
I
G
Y
G
-
A
M
N
Q
R
V
A
R
L
-
A
E
E
K
--
G
--
H
E
I
V
G
V
I
E
N
T
--------------------
P
--
K
--
T
P
Y
Q
Q
Y
Q
H
I
A
D
V
-
K
G
A
D
V
A
I
D
F
S
N
P
N
L
L
F
P
L
L
--
D
E
D
F
H
L
P
L
V
V
A
T
T
G
E
K
E
K
L
L
N
K
L
D
E
L
S
Q
N
M
P
V
F
F
S
A
N
M
S
Y
G
V
H
A
L
T
K
I
L
A
A
A
V
P
L
L
D
D
F
-
D
I
E
L
T
E
A
H
H
N
K
K
V
D
A
P
S
G
T
L
E
K
L
Y
D
V
I
V
S
L
K
E
N
V
----
T
P
V
Y
-
D
R
H
E
L
N
E
K
R
Q
P
Q
D
I
G
I
H
S
I
R
G
G
T
I
V
G
E
H
E
V
L
F
A
G
T
D
E
T
I
Q
I
T
H
R
A
Q
S
K
D
I
F
A
N
G
A
I
Q
A
A
E
R
L
V
N
K
P
N
G
F
Y
T
F
D
N
L
--------
39
HHSearch
69.41
41%
-26
- C1 -
-
3IJP
-
DAPB_BARHE
B:
[21-287]
---
S
M
R
L
T
V
V
G
A
N
G
R
M
G
R
E
L
I
T
A
-
I
Q
R
R
K-
D
--
V
E
L
C
A
V
L
V
R
K
G
S
S
F
V
D
K
D
A
S
I
L
I
G
---
S
--
D
FL
G
--
V
R
--
I
T
D
D
P
E
S
A
F
S
N
T
E
G
I
L
D
F
S
Q
P
Q
A
S
V
L
Y
A
N
Y
A
A
Q
K
S
L
I
H
I
I
G
T
T
G
F
S
K
T
E
E
A
Q
I
A
D
F
A
K
Y
T
T
I
V
K
S
G
N
M
S
L
G
V
N
L
L
A
N
L
V
K
R
A
A
K
A
L
D
D
D
F
D
I
E
I
Y
E
M
H
H
A
N
K
V
D
S
P
S
G
T
A
L
L
L
G
Q
A
A
A
E
G
R
N
I
M
L
K
-
N
V
S
V
N
-
G
R
S
G
H
T
G
K
R
E
K
G
T
I
G
F
A
C
S
R
G
G
T
V
I
G
D
H
S
I
T
F
A
G
E
N
E
R
I
V
L
S
H
I
A
Q
E
R
S
I
F
A
N
G
A
L
K
A
A
L
W
A
K
N
H
E
N
G
L
Y
S
M
L
D
V
L
G
L
N
----
40
HHSearch
69.08
34%
-136
- C1 -
-
3QY9
1
DAPB_STAAC
A:
[3-243]
---
S
M
K
I
L
L
I
G
-
Y
G
A
M
N
Q
R
V
A
R
L
-
A
E
E
K
--
G
--
H
E
I
V
G
V
I
E
N
T
P
K
----
T
----
P
--------------
Y
Q
--
Q
Y
Q
H
I
A
-
D
V
K
G
A
D
V
A
I
D
F
S
N
P
N
L
L
F
P
L
L
D
--
E
D
F
H
L
P
L
V
V
A
T
T
G
E
K
E
K
L
L
N
K
L
D
E
L
S
Q
N
M
P
V
F
F
S
A
N
M
S
Y
G
V
H
A
L
T
K
I
L
A
A
A
V
P
L
L
-
D
D
F
D
I
E
L
T
E
A
H
H
N
K
K
V
D
A
P
S
G
T
L
E
K
L
Y
D
V
I
V
S
L
K
E
N
--
V
-
T
-
P
V
Y
-
D
R
H
E
L
N
E
K
R
Q
P
Q
D
I
G
I
H
S
I
R
G
G
T
I
V
G
E
H
E
V
L
F
A
G
T
D
E
T
I
Q
I
T
H
R
A
Q
S
K
D
I
F
A
N
G
A
I
Q
A
A
E
R
L
V
N
K
P
N
G
F
Y
T
F
D
N
L
--------
29
PsiBlast_CBE
66.14
32%
-129
- C1 -
-
3QY9
1
DAPB_STAAC
B:
[3-243]
---
S
M
K
I
L
L
I
G
Y
G
A
-
M
N
Q
R
V
A
R
L
-
A
E
E
K
--
G
--
H
E
I
V
G
V
I
E
N
T
P
K
A
--------------------
T
--
T
P
Y
Q
Q
Y
Q
H
I
A
D
V
-
K
G
A
D
V
A
I
D
F
S
N
P
N
L
L
F
P
L
L
D
--
E
D
F
H
L
P
L
V
V
A
T
T
G
E
K
E
K
L
L
N
K
L
D
E
L
S
Q
N
M
P
V
F
F
S
A
N
M
S
Y
G
V
H
A
L
T
K
I
L
A
A
A
V
P
L
L
D
D
-
F
D
I
E
L
T
E
A
H
H
N
K
K
V
D
A
P
S
G
T
L
E
K
L
Y
D
V
I
V
-
S
L
K
E
N
V
---
T
P
V
Y
-
D
R
H
E
L
N
E
K
R
Q
P
Q
D
I
G
I
H
S
I
R
G
G
T
I
V
G
E
H
E
V
L
F
A
G
T
D
E
T
I
Q
I
T
H
R
A
Q
S
K
D
I
F
A
N
G
A
I
Q
A
A
E
R
L
V
N
K
P
N
G
F
Y
T
F
D
N
L
--------
60
Fugue
44.68
71%
-94
- C1 -
-
1DIH
1
?
?:
[131-240]
----------------------------------------------------------------------------------------------------------------------------------------------
V
G
V
N
V
M
L
K
L
L
E
K
A
A
K
V
M
G
D
Y
T
D
I
E
I
I
E
A
H
H
R
H
K
V
D
A
P
S
G
T
A
L
A
M
G
E
A
I
A
H
A
L
D
K
D
L
K
-
D
C
A
V
Y
-
S
R
E
G
H
T
G
E
R
V
P
G
T
I
G
F
A
T
V
R
A
G
D
I
V
G
E
H
T
A
M
F
A
D
I
G
E
R
L
E
I
T
H
K
A
S
S
R
-----------------------------------