@TOME V2.3
(Mar 2018)
Ref.
-
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Doc.
Global output mode :
Sort entries by :
Atome Result
Tools Result
PDB occurence
Core Structure Cluster
Sequence Color type :
Secondary Structure
Hydrophobicity
Disulfide Bonds
TCoffee Identity Score
Uniprot annotation
Core Structure Cluster
Contacts with Ligands
Show alignment :
Atome selection
All alignments
Only Template with Ligand
Column output:
Score:
Atome Rank Value
Tools Score
Hide column
Alignment:
Sequence Identity (%)
Tcoffee Alignment Score
Hide column
3D Common Core:
Tito PKB Score
Verify3D Score
QMean Score
Hide column
Structural Clustering:
Cluster Num
3D-Jury Struct. Score
Hide column
Modeller Result :
Model Rank
QMean Score
Dfire Score
Dope Score
Errat Score
Verify3D Score
Modeller Score
Hide column
Complexes Modeling
Show Ligands of Templates
Complexes Affinity Score
Main Binding Site Identity
Hide column
Templates Information:
Uniprot entry
Cath class
Scop class
Smart class
Prosite class
Pfam class
EC Number
Taxonomy
Experiment Method
Hide column
Sequence & Result Tab:
PDB Template Sequence
Complexes Tab
Values color: [
Good
|
Correct
|
Middling
|
Bad
]
Sequence color :
Mutated
Helix
Strand
Conserved
Query sequence : I3TYK0: (2017-12-14 )
MAILKKIDILQAPYVKEMIETTSNLYRLGWDERNGGNISYLLKEEEITPFLDPEKVIRRISMIFDASRLAGCYFIVTGSGRYFKNVASEPAENLGIVRVAEDGKTLELLWGLENECLPTSELPSHFMSHIARLEVDPDNRIVMHCHASHLLAMSFTHELDERSFSRTLWQMCTECLVVFPEGISIIPWMVPGTNEIGEATAEKMKETRLVLWPQHGIYGSGKDMDEVFGLIETAEKAAEVYTYVKAQGPILQTITDENLWHLADAFGVTPKAGYLEEVHTKAGV
Atome Classification :
(25 SA)
.........10........20........30........40........50.-.-......60........70........80........90........100.......110.......120.......130..-.-....140.......150.......160.......170.......180.......190.......200.......210.......220.......230.......240.......250.......260.......270.......280..
(Atome)
(Ident)
(Tito)
(Num)
(QMean)
(Ligand)
(Uniprot)
M
A
I
L
K
K
I
D
ILQ
A
P
Y
V
K
E
M
I
E
T
T
S
N
L
Y
RLGWDERNGG
N
I
S
Y
L
L
KEEEITPFL
D
-
P
-
E
K
V
I
R
R
I
S
M
I
F
D
A
S
RLA
G
C
Y
F
I
V
TGS
G
R
Y
F
K
N
V
ASEPAENL
G
I
V
R
VAEDG
K
T
L
E
L
L
WGLENECL
P
T
S
E
L
P
S
H
F
M
S
H
I
A
R
L
E
-V-DPD
N
R
I
V
M
H
CHA
S
H
L
L
A
M
S
F
T
H
E
L
D
E
R
S
F
S
R
T
L
W
Q
M
C
T
E
C
L
V
VFPEG
I
S
I
I
P
W
MVPGT
N
E
I
G
E
A
T
A
E
K
M
K
ET
R
L
V
L
W
PQHGIYGSGK
D
M
D
E
V
F
G
L
I
E
T
A
E
K
A
A
E
V
Y
T
Y
V
KAQG
P
I
L
Q
TITDE
N
L
W
H
L
A
D
A
FGVTPKA
G
Y
L
E
E
V
H
TKAGV
40
PsiBlast_CBE
89.86
50%
-33
- C2 -
-
2V29
3
RHAD_ECOLI
B:
[3-272]
-------
N
I
T
Q
S
W
F
V
Q
G
M
I
W
A
T
T
D
A
W
L
K
G
W
D
E
R
N
G
G
N
L
T
L
R
L
D
D
A
D
I
A
P
Y
H
D
-
N
F
H
Q
Q
P
R
Y
I
P
L
S
Q
P
M
P
L
L
A
N
T
P
F
I
V
T
G
S
G
K
F
F
R
N
V
Q
L
D
P
A
A
N
L
G
I
V
K
V
D
S
D
G
A
G
Y
H
I
L
W
G
L
T
N
E
A
V
P
T
S
E
L
P
A
H
F
L
S
H
C
E
R
I
K
-
A
T
N
G
K
D
R
V
I
M
H
C
H
A
T
N
L
I
A
L
T
Y
V
L
E
N
D
T
A
V
F
T
R
Q
L
W
E
G
S
T
E
C
L
V
V
F
P
D
G
V
G
I
L
P
W
M
V
P
G
T
D
E
I
G
Q
A
T
A
Q
E
M
Q
K
H
S
L
V
L
W
P
F
H
G
V
F
G
S
G
P
T
L
D
E
T
F
G
L
I
D
T
A
E
K
S
A
Q
V
L
V
K
V
Y
S
M
G
G
M
K
Q
T
I
S
R
E
E
L
I
A
L
G
K
R
F
G
V
T
P
L
A
S
A
L
---------
55
Fugue
89.13
49%
-33
- C2 -
-
1GT7
-
RHAD_ECOLI
A:
[1-274]
-----
M
Q
N
I
T
Q
S
W
F
V
Q
G
M
I
K
A
T
T
D
A
W
L
K
G
W
D
E
R
N
G
G
N
L
T
L
R
L
D
D
A
D
I
A
P
Y
H
D
N
F
-
H
Q
Q
P
R
Y
I
P
L
S
Q
P
M
P
L
L
A
N
T
P
F
I
V
T
G
S
G
K
F
F
R
N
V
Q
L
D
P
A
A
N
L
G
I
V
K
V
D
S
D
G
A
G
Y
H
I
L
W
G
L
T
N
E
A
V
P
T
S
E
L
P
A
H
F
L
S
H
C
E
R
I
K
-
A
T
N
G
K
D
R
V
I
M
H
C
H
A
T
N
L
I
A
L
T
Y
V
L
E
N
D
T
A
V
F
T
R
Q
L
W
E
G
S
T
E
C
L
V
V
F
P
D
G
V
G
I
L
P
W
M
V
P
G
T
D
E
I
G
Q
A
T
A
Q
E
M
Q
K
H
S
L
V
L
W
P
F
H
G
V
F
G
S
G
P
T
L
D
E
T
F
G
L
I
D
T
A
E
K
S
A
Q
V
L
V
K
V
Y
S
M
G
G
M
K
Q
T
I
S
R
E
E
L
I
A
L
G
K
R
F
G
V
T
P
L
A
S
A
L
A
L
-------
51
PsiBlast_CBE
89.11
49%
-34
- C2 -
-
2V9M
4
RHAD_ECOLI
B:
[3-272]
-------
N
I
T
Q
S
W
F
V
Q
G
M
I
K
A
T
T
D
A
W
L
K
G
W
D
E
R
N
G
G
N
L
T
L
R
L
D
D
A
D
I
A
P
Y
H
D
-
N
F
H
Q
Q
P
R
Y
I
P
L
S
Q
P
M
P
L
L
A
N
T
P
F
I
V
T
G
S
G
K
F
F
R
N
V
Q
L
D
P
M
A
N
L
G
I
V
K
V
D
S
D
G
A
G
Y
H
I
L
W
G
L
F
N
E
A
V
P
T
S
E
L
P
A
H
F
L
S
H
C
E
R
I
K
-
A
T
N
G
K
D
R
V
I
M
H
C
H
A
T
N
L
I
A
L
T
Y
V
L
E
N
D
T
A
V
F
T
R
Q
L
W
E
G
S
T
E
C
L
V
V
F
P
D
G
V
G
I
L
P
W
M
V
P
G
T
D
A
I
G
Q
A
T
A
Q
E
M
Q
K
H
S
L
V
L
W
P
F
H
G
V
F
G
S
G
P
T
L
D
E
T
F
G
L
I
D
T
A
E
K
S
A
Q
V
L
V
K
V
Y
S
M
G
G
M
K
Q
T
I
S
R
E
E
L
I
A
L
G
K
R
F
G
V
T
P
L
A
S
A
L
---------
53
PsiBlast_CBE
89.06
49%
-32
- C2 -
-
2V9G
2
RHAD_ECOLI
C:
[3-272]
-------
N
I
T
Y
S
W
F
V
Q
G
M
I
K
A
T
T
D
A
W
L
K
G
W
D
E
R
N
G
G
N
L
T
L
R
L
D
D
A
D
I
A
P
Y
H
D
-
N
F
H
Q
Q
P
R
Y
I
P
L
S
Q
P
M
P
L
L
A
N
T
P
F
I
V
T
G
S
G
K
F
F
R
N
V
Q
W
D
P
A
A
N
L
G
I
V
K
V
D
S
D
G
A
G
Y
H
I
L
W
G
L
T
N
E
A
V
P
T
S
E
L
P
A
H
F
L
S
H
C
E
R
I
K
-
A
T
N
G
K
D
R
V
I
M
H
C
H
A
T
N
L
I
A
L
T
Y
V
L
E
N
D
T
A
V
F
T
R
Q
L
W
E
G
S
T
E
C
L
V
V
F
P
D
G
V
G
I
L
P
W
M
V
P
G
T
D
A
I
G
Q
A
T
A
Q
E
M
Q
K
H
S
L
V
L
W
P
F
H
G
V
F
G
S
G
P
T
L
D
E
T
F
G
L
I
D
T
A
E
K
S
A
Q
V
L
V
K
V
Y
S
M
G
G
M
K
Q
T
I
S
R
E
E
L
I
A
L
G
K
R
F
G
V
T
P
L
A
S
A
L
---------
52
PsiBlast_CBE
88.69
49%
-30
- C2 -
-
2V9G
2
RHAD_ECOLI
D:
[3-272]
-------
N
I
T
Y
S
W
F
V
Q
G
M
I
K
A
T
T
D
A
W
L
K
G
W
D
E
R
N
G
G
N
L
T
L
R
L
D
D
A
D
I
A
P
Y
H
D
-
N
F
H
Q
Q
P
R
Y
I
P
L
S
Q
P
M
P
L
L
A
N
T
P
F
I
V
T
G
S
G
K
F
F
R
N
V
Q
W
D
P
A
A
N
L
G
I
V
K
V
D
S
D
G
A
G
Y
H
I
L
W
G
L
T
N
E
A
V
P
T
S
E
L
P
A
H
F
L
S
H
C
E
R
I
K
-
A
T
N
G
K
D
R
V
I
M
H
C
H
A
T
N
L
I
A
L
T
Y
V
L
E
N
D
T
A
V
F
T
R
Q
L
W
E
G
S
T
E
C
L
V
V
F
P
D
G
V
G
I
L
P
W
M
V
P
G
T
D
A
I
G
Q
A
T
A
Q
E
M
Q
K
H
S
L
V
L
W
P
F
H
G
V
F
G
S
G
P
T
L
D
E
T
F
G
L
I
D
T
A
E
K
S
A
Q
V
L
V
K
V
Y
S
M
G
G
M
K
Q
T
I
S
R
E
E
L
I
A
L
G
K
R
F
G
V
T
P
L
A
S
A
L
---------
43
PsiBlast_CBE
88.36
49%
-30
- C2 -
-
2V9N
2
RHAD_ECOLI
D:
[3-272]
-------
N
I
T
Q
S
W
F
V
Q
G
M
I
K
A
T
T
D
A
W
L
K
G
W
D
E
R
N
G
G
N
L
T
L
R
L
D
D
A
D
I
A
P
Y
H
D
-
N
F
H
Q
Q
P
R
Y
I
P
L
S
Q
P
M
P
L
L
A
N
T
P
F
I
V
T
G
S
G
K
F
F
R
N
V
Q
L
D
P
A
F
N
L
G
I
V
K
V
D
S
D
G
A
G
Y
H
I
L
W
G
L
T
N
E
A
V
P
T
S
E
L
P
A
H
F
L
S
H
C
E
R
I
K
A
T
-
N
G
K
D
R
V
I
M
H
C
H
A
T
N
L
I
A
L
T
Y
V
L
E
N
D
T
A
V
F
T
R
Q
L
W
E
G
S
T
E
C
L
V
V
F
P
D
G
V
G
I
L
P
W
M
V
P
G
T
D
A
I
G
Q
A
T
A
Q
E
M
Q
K
H
S
L
V
L
W
P
F
H
G
V
F
G
S
G
P
T
L
D
E
T
F
G
L
I
D
T
A
E
K
S
A
Q
V
L
V
K
V
Y
S
M
G
G
M
K
Q
T
I
S
R
E
E
L
I
A
L
G
K
R
F
G
V
T
P
L
A
S
A
L
---------
3
PsiBlast_PDB
88.32
49%
-29
- C2 -
-
1OJR
6
RHAD_ECOLI
A:
[3-272]
-------
N
I
T
Q
S
W
F
V
Q
G
M
I
K
A
T
T
D
A
W
L
K
G
W
D
E
R
N
G
G
N
L
T
L
R
L
D
D
A
D
I
A
P
Y
H
D
-
N
F
H
Q
Q
P
R
Y
I
P
L
S
Q
P
M
P
L
L
A
N
T
P
F
I
V
T
G
S
G
K
F
F
R
N
V
Q
L
D
P
A
A
N
L
G
I
V
K
V
D
S
D
G
A
G
Y
H
I
L
W
G
L
T
N
E
A
V
P
T
S
E
L
P
A
H
F
L
S
H
C
E
R
I
K
-
A
T
N
G
K
D
R
V
I
M
H
C
H
A
T
N
L
I
A
L
T
Y
V
L
E
N
D
T
A
V
F
T
R
Q
L
W
E
G
S
T
E
C
L
V
V
F
P
D
G
V
G
I
L
P
W
M
V
P
G
T
D
A
I
G
Q
A
T
A
Q
E
M
Q
K
H
S
L
V
L
W
P
F
H
G
V
F
G
S
G
P
T
L
D
E
T
F
G
L
I
D
T
A
E
K
S
A
Q
V
L
V
K
V
Y
S
M
G
G
M
K
Q
T
I
S
R
E
E
L
I
A
L
G
K
R
F
G
V
T
P
L
A
S
A
L
---------
1
PsiBlast_PDB
88.29
50%
-32
- C2 -
-
1GT7
-
RHAD_ECOLI
A:
[3-272]
-------
N
I
T
Q
S
W
F
V
Q
G
M
I
K
A
T
T
D
A
W
L
K
G
W
D
E
R
N
G
G
N
L
T
L
R
L
D
D
A
D
I
A
P
Y
H
D
-
N
F
H
Q
Q
P
R
Y
I
P
L
S
Q
P
M
P
L
L
A
N
T
P
F
I
V
T
G
S
G
K
F
F
R
N
V
Q
L
D
P
A
A
N
L
G
I
V
K
V
D
S
D
G
A
G
Y
H
I
L
W
G
L
T
N
E
A
V
P
T
S
E
L
P
A
H
F
L
S
H
C
E
R
I
K
-
A
T
N
G
K
D
R
V
I
M
H
C
H
A
T
N
L
I
A
L
T
Y
V
L
E
N
D
T
A
V
F
T
R
Q
L
W
E
G
S
T
E
C
L
V
V
F
P
D
G
V
G
I
L
P
W
M
V
P
G
T
D
E
I
G
Q
A
T
A
Q
E
M
Q
K
H
S
L
V
L
W
P
F
H
G
V
F
G
S
G
P
T
L
D
E
T
F
G
L
I
D
T
A
E
K
S
A
Q
V
L
V
K
V
Y
S
M
G
G
M
K
Q
T
I
S
R
E
E
L
I
A
L
G
K
R
F
G
V
T
P
L
A
S
A
L
---------
2
PsiBlast_PDB
88.28
50%
-33
- C2 -
-
2V29
3
RHAD_ECOLI
A:
[3-272]
-------
N
I
T
Q
S
W
F
V
Q
G
M
I
W
A
T
T
D
A
W
L
K
G
W
D
E
R
N
G
G
N
L
T
L
R
L
D
D
A
D
I
A
P
Y
H
D
-
N
F
H
Q
Q
P
R
Y
I
P
L
S
Q
P
M
P
L
L
A
N
T
P
F
I
V
T
G
S
G
K
F
F
R
N
V
Q
L
D
P
A
A
N
L
G
I
V
K
V
D
S
D
G
A
G
Y
H
I
L
W
G
L
T
N
E
A
V
P
T
S
E
L
P
A
H
F
L
S
H
C
E
R
I
K
-
A
T
N
G
K
D
R
V
I
M
H
C
H
A
T
N
L
I
A
L
T
Y
V
L
E
N
D
T
A
V
F
T
R
Q
L
W
E
G
S
T
E
C
L
V
V
F
P
D
G
V
G
I
L
P
W
M
V
P
G
T
D
E
I
G
Q
A
T
A
Q
E
M
Q
K
H
S
L
V
L
W
P
F
H
G
V
F
G
S
G
P
T
L
D
E
T
F
G
L
I
D
T
A
E
K
S
A
Q
V
L
V
K
V
Y
S
M
G
G
M
K
Q
T
I
S
R
E
E
L
I
A
L
G
K
R
F
G
V
T
P
L
A
S
A
L
---------
15
PsiBlast_PDB
88.23
48%
-37
- C2 -
-
2V2B
1
RHAD_ECOLI
A:
[3-272]
-------
N
I
T
Q
S
W
F
V
Q
G
M
I
K
A
T
T
D
A
W
L
K
G
W
D
E
R
N
G
G
N
L
T
L
R
L
D
D
A
D
I
A
P
Y
H
D
-
N
F
H
Q
Q
P
R
Y
I
P
L
S
Q
P
M
P
L
L
A
N
T
P
F
I
V
T
G
S
G
K
F
F
R
N
V
Q
L
D
P
A
A
N
L
G
I
V
K
V
D
S
D
G
A
G
Y
H
I
L
W
G
L
T
N
E
A
V
P
T
S
S
L
P
A
H
F
L
S
H
C
E
R
I
K
-
A
T
N
G
K
D
R
V
I
M
H
C
H
A
T
N
L
I
A
L
T
Y
V
L
E
N
D
T
A
V
F
T
R
Q
L
W
E
G
S
T
E
C
L
V
V
F
P
D
G
V
G
I
L
P
W
M
V
P
G
T
D
A
I
G
Q
A
T
A
Q
E
M
Q
K
H
S
L
V
L
W
P
F
H
G
V
F
G
S
G
P
T
L
D
E
T
F
G
L
I
D
T
A
E
K
S
A
Q
V
L
V
K
V
Y
S
M
G
G
M
G
Q
T
I
S
A
A
E
L
I
A
L
G
K
R
F
G
V
T
P
L
A
S
A
L
---------
11
PsiBlast_PDB
88.23
50%
-27
- C2 -
-
2V9L
8
RHAD_ECOLI
A:
[9-272]
-------------
F
V
Q
G
M
I
K
A
T
T
D
A
W
L
K
G
W
D
E
R
N
G
G
N
L
T
L
R
L
D
D
A
D
I
A
P
Y
H
D
-
N
F
H
Q
Q
P
R
Y
I
P
L
S
Q
P
M
P
L
L
A
N
T
P
F
I
V
T
G
S
G
K
F
F
R
N
V
Q
L
D
P
A
A
N
L
G
I
V
K
V
D
S
D
G
A
G
Y
H
I
L
W
G
L
T
N
E
A
V
P
T
S
E
L
P
A
H
F
L
S
H
C
E
R
I
K
A
T
-
N
G
K
D
R
V
I
M
H
C
H
A
T
N
L
I
A
L
T
Y
V
L
E
N
D
T
A
V
F
T
R
Q
L
W
E
G
S
T
E
C
L
V
V
F
P
D
G
V
G
I
L
P
W
M
V
P
G
T
D
A
I
G
Q
A
T
A
Q
E
M
Q
K
H
S
L
V
L
W
P
F
H
G
V
F
G
S
G
P
T
L
D
E
T
F
G
L
I
D
T
A
E
K
S
A
Q
V
L
V
K
V
Y
S
M
G
G
M
K
Q
T
I
S
R
E
E
L
I
A
L
G
K
R
F
G
V
T
P
L
A
S
A
L
---------
45
PsiBlast_CBE
88.18
49%
-29
- C2 -
-
2V9N
6
RHAD_ECOLI
B:
[3-272]
-------
N
I
T
Q
S
W
F
V
Q
G
M
I
K
A
T
T
D
A
W
L
K
G
W
D
E
R
N
G
G
N
L
T
L
R
L
D
D
A
D
I
A
P
Y
H
D
-
N
F
H
Q
Q
P
R
Y
I
P
L
S
Q
P
M
P
L
L
A
N
T
P
F
I
V
T
G
S
G
K
F
F
R
N
V
Q
L
D
P
A
F
N
L
G
I
V
K
V
D
S
D
G
A
G
Y
H
I
L
W
G
L
T
N
E
A
V
P
T
S
E
L
P
A
H
F
L
S
H
C
E
R
I
K
A
T
-
N
G
K
D
R
V
I
M
H
C
H
A
T
N
L
I
A
L
T
Y
V
L
E
N
D
T
A
V
F
T
R
Q
L
W
E
G
S
T
E
C
L
V
V
F
P
D
G
V
G
I
L
P
W
M
V
P
G
T
D
A
I
G
Q
A
T
A
Q
E
M
Q
K
H
S
L
V
L
W
P
F
H
G
V
F
G
S
G
P
T
L
D
E
T
F
G
L
I
D
T
A
E
K
S
A
Q
V
L
V
K
V
Y
S
M
G
G
M
K
Q
T
I
S
R
E
E
L
I
A
L
G
K
R
F
G
V
T
P
L
A
S
A
L
---------
13
PsiBlast_PDB
88.05
49%
-31
- C2 -
-
2V9O
-
RHAD_ECOLI
A:
[3-272]
-------
N
I
T
Q
S
W
F
V
Q
G
M
I
K
A
T
T
D
A
W
L
K
G
W
D
E
R
N
G
G
N
L
T
L
R
L
D
D
A
D
I
A
P
Y
H
D
-
N
F
H
Q
Q
P
R
Y
I
P
L
S
Q
P
M
P
L
L
A
N
T
P
F
I
V
T
G
S
G
K
F
F
R
N
V
Q
L
D
P
M
A
N
L
G
I
V
K
V
D
S
D
G
A
G
Y
H
I
L
W
G
L
F
N
E
A
V
P
T
S
E
L
P
A
H
F
L
S
H
C
E
R
I
K
-
A
T
N
G
K
D
R
V
I
M
H
C
H
A
T
N
L
I
A
L
T
Y
V
L
E
N
D
T
A
V
F
T
R
Q
L
W
E
G
S
T
E
C
L
V
V
F
P
D
G
V
G
I
L
P
W
M
V
P
G
T
D
A
I
G
Q
A
T
A
Q
E
M
Q
K
H
S
L
V
L
W
P
F
H
G
V
F
G
S
G
P
T
L
D
E
T
F
G
L
I
D
T
A
E
K
S
A
Q
V
L
V
K
V
Y
S
M
G
G
M
K
Q
T
I
S
R
E
E
L
I
A
L
G
K
R
F
G
V
T
P
L
A
S
A
L
---------
44
PsiBlast_CBE
88.03
49%
-31
- C2 -
-
2V9N
6
RHAD_ECOLI
C:
[3-272]
-------
N
I
T
Q
S
W
F
V
Q
G
M
I
K
A
T
T
D
A
W
L
K
G
W
D
E
R
N
G
G
N
L
T
L
R
L
D
D
A
D
I
A
P
Y
H
D
-
N
F
H
Q
Q
P
R
Y
I
P
L
S
Q
P
M
P
L
L
A
N
T
P
F
I
V
T
G
S
G
K
F
F
R
N
V
Q
L
D
P
A
F
N
L
G
I
V
K
V
D
S
D
G
A
G
Y
H
I
L
W
G
L
T
N
E
A
V
P
T
S
E
L
P
A
H
F
L
S
H
C
E
R
I
K
A
T
-
N
G
K
D
R
V
I
M
H
C
H
A
T
N
L
I
A
L
T
Y
V
L
E
N
D
T
A
V
F
T
R
Q
L
W
E
G
S
T
E
C
L
V
V
F
P
D
G
V
G
I
L
P
W
M
V
P
G
T
D
A
I
G
Q
A
T
A
Q
E
M
Q
K
H
S
L
V
L
W
P
F
H
G
V
F
G
S
G
P
T
L
D
E
T
F
G
L
I
D
T
A
E
K
S
A
Q
V
L
V
K
V
Y
S
M
G
G
M
K
Q
T
I
S
R
E
E
L
I
A
L
G
K
R
F
G
V
T
P
L
A
S
A
L
---------
48
PsiBlast_CBE
87.97
50%
-29
- C2 -
-
2UYV
2
RHAD_ECOLI
C:
[9-272]
-------------
F
V
Q
G
M
I
K
A
T
T
D
A
W
L
K
G
W
D
E
R
N
G
G
N
L
T
L
R
L
D
D
A
D
I
A
P
Y
H
D
-
N
F
H
Q
Q
P
R
Y
I
P
L
S
Q
P
M
P
L
L
A
N
T
P
F
I
V
T
G
S
G
K
F
F
R
N
V
Q
L
D
P
A
A
N
L
G
I
V
K
V
D
S
D
G
A
G
Y
H
I
L
W
G
L
T
N
E
A
V
P
T
S
E
L
P
A
H
F
L
S
H
C
E
R
I
K
A
T
-
N
G
K
D
R
V
I
M
H
C
H
A
T
N
L
I
A
L
T
Y
V
L
E
N
D
T
A
V
F
T
R
Q
L
W
E
G
S
T
E
C
L
V
V
F
P
D
G
V
G
I
L
P
W
M
V
P
G
T
D
A
I
G
Q
A
T
A
Q
E
M
Q
K
H
S
L
V
L
W
P
F
H
G
V
F
G
S
G
P
T
L
D
E
T
F
G
L
I
D
T
A
E
K
S
A
Q
V
L
V
K
V
Y
S
M
G
G
M
K
Q
T
I
S
R
E
E
L
I
A
L
G
K
R
F
G
V
T
P
L
A
S
A
L
---------
54
PsiBlast_CBE
87.91
49%
-33
- C2 -
-
2V9G
3
RHAD_ECOLI
B:
[3-272]
-------
N
I
T
Y
S
W
F
V
Q
G
M
I
K
A
T
T
D
A
W
L
K
G
W
D
E
R
N
G
G
N
L
T
L
R
L
D
D
A
D
I
A
P
Y
H
D
-
N
F
H
Q
Q
P
R
Y
I
P
L
S
Q
P
M
P
L
L
A
N
T
P
F
I
V
T
G
S
G
K
F
F
R
N
V
Q
W
D
P
A
A
N
L
G
I
V
K
V
D
S
D
G
A
G
Y
H
I
L
W
G
L
T
N
E
A
V
P
T
S
E
L
P
A
H
F
L
S
H
C
E
R
I
K
-
A
T
N
G
K
D
R
V
I
M
H
C
H
A
T
N
L
I
A
L
T
Y
V
L
E
N
D
T
A
V
F
T
R
Q
L
W
E
G
S
T
E
C
L
V
V
F
P
D
G
V
G
I
L
P
W
M
V
P
G
T
D
A
I
G
Q
A
T
A
Q
E
M
Q
K
H
S
L
V
L
W
P
F
H
G
V
F
G
S
G
P
T
L
D
E
T
F
G
L
I
D
T
A
E
K
S
A
Q
V
L
V
K
V
Y
S
M
G
G
M
K
Q
T
I
S
R
E
E
L
I
A
L
G
K
R
F
G
V
T
P
L
A
S
A
L
---------
42
PsiBlast_CBE
87.85
49%
-30
- C2 -
-
2V9I
1
RHAD_ECOLI
B:
[3-272]
-------
N
I
T
Q
S
W
F
V
Q
G
M
I
K
A
T
T
D
A
W
L
K
G
W
D
E
R
N
G
G
N
L
T
L
R
L
D
D
A
D
I
A
P
Y
H
D
-
N
F
H
Q
Q
P
R
Y
I
P
L
S
Q
P
M
P
L
L
A
N
T
P
F
I
V
T
G
S
G
K
F
F
R
N
V
Q
L
D
P
A
A
N
L
G
I
V
K
V
D
S
D
G
A
G
Y
H
I
L
W
G
L
T
N
E
A
V
P
T
S
E
L
P
A
H
F
L
S
H
C
E
R
I
K
-
A
T
N
G
K
D
R
V
I
M
H
C
H
A
T
N
L
I
A
L
T
Y
V
L
E
N
D
T
A
V
F
T
R
Q
L
W
E
G
S
T
E
C
L
V
V
F
P
D
G
V
G
I
L
P
W
M
V
P
G
T
D
A
I
G
Q
A
T
A
Q
E
M
Q
K
H
S
L
V
L
W
P
F
H
G
V
F
G
S
G
P
T
L
D
E
T
F
G
L
I
D
T
A
E
K
S
A
Q
V
L
V
K
V
Y
S
M
G
G
M
W
Q
T
I
S
R
E
E
L
I
A
L
G
K
R
F
G
V
T
P
L
A
S
A
L
---------
8
PsiBlast_PDB
87.84
49%
-29
- C2 -
-
2V9N
4
RHAD_ECOLI
A:
[3-272]
-------
N
I
T
Q
S
W
F
V
Q
G
M
I
K
A
T
T
D
A
W
L
K
G
W
D
E
R
N
G
G
N
L
T
L
R
L
D
D
A
D
I
A
P
Y
H
D
-
N
F
H
Q
Q
P
R
Y
I
P
L
S
Q
P
M
P
L
L
A
N
T
P
F
I
V
T
G
S
G
K
F
F
R
N
V
Q
L
D
P
A
F
N
L
G
I
V
K
V
D
S
D
G
A
G
Y
H
I
L
W
G
L
T
N
E
A
V
P
T
S
E
L
P
A
H
F
L
S
H
C
E
R
I
K
A
T
-
N
G
K
D
R
V
I
M
H
C
H
A
T
N
L
I
A
L
T
Y
V
L
E
N
D
T
A
V
F
T
R
Q
L
W
E
G
S
T
E
C
L
V
V
F
P
D
G
V
G
I
L
P
W
M
V
P
G
T
D
A
I
G
Q
A
T
A
Q
E
M
Q
K
H
S
L
V
L
W
P
F
H
G
V
F
G
S
G
P
T
L
D
E
T
F
G
L
I
D
T
A
E
K
S
A
Q
V
L
V
K
V
Y
S
M
G
G
M
K
Q
T
I
S
R
E
E
L
I
A
L
G
K
R
F
G
V
T
P
L
A
S
A
L
---------
12
PsiBlast_PDB
87.78
49%
-35
- C2 -
-
2V9M
5
RHAD_ECOLI
A:
[3-272]
-------
N
I
T
Q
S
W
F
V
Q
G
M
I
K
A
T
T
D
A
W
L
K
G
W
D
E
R
N
G
G
N
L
T
L
R
L
D
D
A
D
I
A
P
Y
H
D
-
N
F
H
Q
Q
P
R
Y
I
P
L
S
Q
P
M
P
L
L
A
N
T
P
F
I
V
T
G
S
G
K
F
F
R
N
V
Q
L
D
P
M
A
N
L
G
I
V
K
V
D
S
D
G
A
G
Y
H
I
L
W
G
L
F
N
E
A
V
P
T
S
E
L
P
A
H
F
L
S
H
C
E
R
I
K
-
A
T
N
G
K
D
R
V
I
M
H
C
H
A
T
N
L
I
A
L
T
Y
V
L
E
N
D
T
A
V
F
T
R
Q
L
W
E
G
S
T
E
C
L
V
V
F
P
D
G
V
G
I
L
P
W
M
V
P
G
T
D
A
I
G
Q
A
T
A
Q
E
M
Q
K
H
S
L
V
L
W
P
F
H
G
V
F
G
S
G
P
T
L
D
E
T
F
G
L
I
D
T
A
E
K
S
A
Q
V
L
V
K
V
Y
S
M
G
G
M
K
Q
T
I
S
R
E
E
L
I
A
L
G
K
R
F
G
V
T
P
L
A
S
A
L
---------
7
PsiBlast_PDB
87.78
49%
-32
- C2 -
-
2UYU
-
RHAD_ECOLI
A:
[3-272]
-------
N
I
T
Q
S
W
F
V
Q
G
M
I
K
A
T
T
D
A
W
L
K
G
W
D
E
R
N
G
G
N
L
T
L
R
L
D
D
A
D
I
A
P
Y
H
D
-
N
F
H
Q
Q
P
R
Y
I
P
L
S
Q
P
M
P
L
L
A
N
T
P
F
I
V
T
G
S
G
K
F
F
R
N
V
Q
L
D
P
A
F
N
L
G
I
V
K
V
D
S
D
G
A
G
Y
H
I
L
W
G
L
T
N
E
A
V
P
T
S
E
L
P
A
H
F
L
S
H
C
E
R
I
K
A
T
-
N
G
K
D
R
V
I
M
H
C
H
A
T
N
L
I
A
L
T
Y
V
L
E
N
D
T
A
V
F
T
R
Q
L
W
E
G
S
T
E
C
L
V
V
F
P
D
G
V
G
I
L
P
W
M
V
P
G
T
D
A
I
G
Q
A
T
A
Q
E
M
Q
K
H
S
L
V
L
W
P
F
H
G
V
F
G
S
G
P
T
L
D
E
T
F
G
L
I
D
T
A
E
K
S
A
Q
V
L
V
K
V
Y
S
M
G
G
M
K
Q
T
I
S
R
E
E
L
I
A
L
G
K
R
F
G
V
T
P
L
A
S
A
L
---------
9
PsiBlast_PDB
87.62
49%
-30
- C2 -
-
2V2A
1
RHAD_ECOLI
A:
[3-272]
-------
N
I
T
Q
S
W
F
V
Q
G
M
I
K
A
T
T
D
A
W
L
K
G
W
D
E
R
N
G
G
N
L
T
L
R
L
D
D
A
D
I
A
P
Y
H
D
-
N
F
H
Q
Q
P
R
Y
I
P
L
S
Q
P
M
P
L
L
A
N
T
P
F
I
V
T
G
S
G
K
F
F
R
N
V
Q
L
D
P
A
A
N
L
G
I
V
K
V
D
S
D
G
A
G
Y
H
I
L
W
G
L
T
N
E
A
V
P
T
S
E
L
P
A
H
F
L
S
H
C
E
R
I
K
-
A
T
N
G
K
D
R
V
I
M
H
C
H
A
T
N
L
I
A
L
T
Y
V
L
E
N
D
T
A
V
F
T
R
Q
L
W
E
G
S
T
E
C
L
V
V
F
P
D
G
V
G
I
L
P
W
M
V
P
G
T
D
A
I
G
Q
A
T
A
Q
E
M
Q
K
H
S
L
V
L
W
P
F
H
G
V
F
G
S
G
P
T
L
D
E
T
F
G
L
I
D
T
A
E
K
S
A
Q
V
L
V
K
V
Y
S
M
G
G
M
G
Q
T
I
S
A
A
E
L
I
A
L
G
K
R
F
G
V
T
P
L
A
S
A
L
---------
14
PsiBlast_PDB
87.58
49%
-29
- C2 -
-
2V9G
1
RHAD_ECOLI
A:
[3-272]
-------
N
I
T
Y
S
W
F
V
Q
G
M
I
K
A
T
T
D
A
W
L
K
G
W
D
E
R
N
G
G
N
L
T
L
R
L
D
D
A
D
I
A
P
Y
H
D
-
N
F
H
Q
Q
P
R
Y
I
P
L
S
Q
P
M
P
L
L
A
N
T
P
F
I
V
T
G
S
G
K
F
F
R
N
V
Q
W
D
P
A
A
N
L
G
I
V
K
V
D
S
D
G
A
G
Y
H
I
L
W
G
L
T
N
E
A
V
P
T
S
E
L
P
A
H
F
L
S
H
C
E
R
I
K
-
A
T
N
G
K
D
R
V
I
M
H
C
H
A
T
N
L
I
A
L
T
Y
V
L
E
N
D
T
A
V
F
T
R
Q
L
W
E
G
S
T
E
C
L
V
V
F
P
D
G
V
G
I
L
P
W
M
V
P
G
T
D
A
I
G
Q
A
T
A
Q
E
M
Q
K
H
S
L
V
L
W
P
F
H
G
V
F
G
S
G
P
T
L
D
E
T
F
G
L
I
D
T
A
E
K
S
A
Q
V
L
V
K
V
Y
S
M
G
G
M
K
Q
T
I
S
R
E
E
L
I
A
L
G
K
R
F
G
V
T
P
L
A
S
A
L
---------
10
PsiBlast_PDB
86.52
50%
-24
- C2 -
-
2UYV
2
RHAD_ECOLI
A:
[9-272]
-------------
F
V
Q
G
M
I
K
A
T
T
D
A
W
L
K
G
W
D
E
R
N
G
G
N
L
T
L
R
L
D
D
A
D
I
A
P
Y
H
D
-
N
F
H
Q
Q
P
R
Y
I
P
L
S
Q
P
M
P
L
L
A
N
T
P
F
I
V
T
G
S
G
K
F
F
R
N
V
Q
L
D
P
A
A
N
L
G
I
V
K
V
D
S
D
G
A
G
Y
H
I
L
W
G
L
T
N
E
A
V
P
T
S
E
L
P
A
H
F
L
S
H
C
E
R
I
K
A
T
-
N
G
K
D
R
V
I
M
H
C
H
A
T
N
L
I
A
L
T
Y
V
L
E
N
D
T
A
V
F
T
R
Q
L
W
E
G
S
T
E
C
L
V
V
F
P
D
G
V
G
I
L
P
W
M
V
P
G
T
D
A
I
G
Q
A
T
A
Q
E
M
Q
K
H
S
L
V
L
W
P
F
H
G
V
F
G
S
G
P
T
L
D
E
T
F
G
L
I
D
T
A
E
K
S
A
Q
V
L
V
K
V
Y
S
M
G
G
M
K
Q
T
I
S
R
E
E
L
I
A
L
G
K
R
F
G
V
T
P
L
A
S
A
L
---------
49
PsiBlast_CBE
85.69
50%
-28
- C2 -
-
2UYV
2
RHAD_ECOLI
B:
[9-272]
-------------
F
V
Q
G
M
I
K
A
T
T
D
A
W
L
K
G
W
D
E
R
N
G
G
N
L
T
L
R
L
D
D
A
D
I
A
P
Y
H
D
-
N
F
H
Q
Q
P
R
Y
I
P
L
S
Q
P
M
P
L
L
A
N
T
P
F
I
V
T
G
S
G
K
F
F
R
N
V
Q
L
D
P
A
A
N
L
G
I
V
K
V
D
S
D
G
A
G
Y
H
I
L
W
G
L
T
N
E
A
V
P
T
S
E
L
P
A
H
F
L
S
H
C
E
R
I
K
A
T
-
N
G
K
D
R
V
I
M
H
C
H
A
T
N
L
I
A
L
T
Y
V
L
E
N
D
T
A
V
F
T
R
Q
L
W
E
G
S
T
E
C
L
V
V
F
P
D
G
V
G
I
L
P
W
M
V
P
G
T
D
A
I
G
Q
A
T
A
Q
E
M
Q
K
H
S
L
V
L
W
P
F
H
G
V
F
G
S
G
P
T
L
D
E
T
F
G
L
I
D
T
A
E
K
S
A
Q
V
L
V
K
V
Y
S
M
G
G
M
K
Q
T
I
S
R
E
E
L
I
A
L
G
K
R
F
G
V
T
P
L
A
S
A
L
---------
47
PsiBlast_CBE
84.92
50%
-21
- C2 -
-
2UYV
2
RHAD_ECOLI
D:
[9-272]
-------------
F
V
Q
G
M
I
K
A
T
T
D
A
W
L
K
G
W
D
E
R
N
G
G
N
L
T
L
R
L
D
D
A
D
I
A
P
Y
H
D
-
N
F
H
Q
Q
P
R
Y
I
P
L
S
Q
P
M
P
L
L
A
N
T
P
F
I
V
T
G
S
G
K
F
F
R
N
V
Q
L
D
P
A
A
N
L
G
I
V
K
V
D
S
D
G
A
G
Y
H
I
L
W
G
L
T
N
E
A
V
P
T
S
E
L
P
A
H
F
L
S
H
C
E
R
I
K
A
T
-
N
G
K
D
R
V
I
M
H
C
H
A
T
N
L
I
A
L
T
Y
V
L
E
N
D
T
A
V
F
T
R
Q
L
W
E
G
S
T
E
C
L
V
V
F
P
D
G
V
G
I
L
P
W
M
V
P
G
T
D
A
I
G
Q
A
T
A
Q
E
M
Q
K
H
S
L
V
L
W
P
F
H
G
V
F
G
S
G
P
T
L
D
E
T
F
G
L
I
D
T
A
E
K
S
A
Q
V
L
V
K
V
Y
S
M
G
G
M
K
Q
T
I
S
R
E
E
L
I
A
L
G
K
R
F
G
V
T
P
L
A
S
A
L
---------