@TOME V2.3
(Mar 2018)
Ref.
-
-
Doc.
Global output mode :
Sort entries by :
Atome Result
Tools Result
PDB occurence
Core Structure Cluster
Sequence Color type :
Secondary Structure
Hydrophobicity
Disulfide Bonds
TCoffee Identity Score
Uniprot annotation
Core Structure Cluster
Contacts with Ligands
Show alignment :
Atome selection
All alignments
Only Template with Ligand
Column output:
Score:
Atome Rank Value
Tools Score
Hide column
Alignment:
Sequence Identity (%)
Tcoffee Alignment Score
Hide column
3D Common Core:
Tito PKB Score
Verify3D Score
QMean Score
Hide column
Structural Clustering:
Cluster Num
3D-Jury Struct. Score
Hide column
Modeller Result :
Model Rank
QMean Score
Dfire Score
Dope Score
Errat Score
Verify3D Score
Modeller Score
Hide column
Complexes Modeling
Show Ligands of Templates
Complexes Affinity Score
Main Binding Site Identity
Hide column
Templates Information:
Uniprot entry
Cath class
Scop class
Smart class
Prosite class
Pfam class
EC Number
Taxonomy
Experiment Method
Hide column
Sequence & Result Tab:
PDB Template Sequence
Complexes Tab
Values color: [
Good
|
Correct
|
Middling
|
Bad
]
Sequence color :
Mutated
Helix
Strand
Conserved
Query sequence : I3TYZ3: (2017-12-15 )
MVIKKKREKEMFENKKIKINVSDFQKVSAVTAVMMQTILSFALANSHSATNTAFLGTFYVIVKYTAPMFIFAIVYNMVKTSQHLSYWEFLKEKFFELVVPYLLWTTAYLWLFPAVQQQTPYTDTASFLLKYVTGDGAPHLWYTVMMLQIQLFMPFFVWLGYKVFANKKYVWPVLIGSTILYVAWYLFYQTQVLTGPYHDSWYLLDRFVASFMIYGVAAFVYHEKVYQYLDRVRYLFLPVALVIAFFSVRSLLAHPGDLSFANAPYLNTIQSLYSLVIIFAVFIGASKMIVNDSPKLPLFKWLSVYAYRTYLANVFVFQVLLLLFKDSWLQLPSGVMILVAYLMTASCAFALSWLLHIIWVAIKKGFSK
Atome Classification :
(20 SA)
------------------....-----....-.10........20........30......-----..40........50........60........------------------------70........80........90--------.........100.......-110.......120........130..---.-.....140.......150.......-160.......170.......180.......190....-...200--........210.......------220.......230....------...240..-----------------------------.....250.......260----........270....----------------.-..280.......290...----------------..-..300.-......310.-.-----------.....320.....-.------.330.......340......--.350..-------------.....360......------------------------------------------------------------
(Atome)
(Ident)
(Tito)
(Num)
(QMean)
(Ligand)
(Uniprot)
------------------MVI
K
-----
K
K
R
E
-
K
E
M
FEN
K
K
I
K
I
N
V
S
D
F
Q
K
V
S
A
V
T
A
V
M
M
Q
T
-----
I
L
S
F
A
LANSHSATN
T
A
F
L
G
T
F
Y
V
I
V
K
YTA
P
M
F
------------------------
I
F
A
I
V
Y
N
M
V
KTSQ
H
L
S
Y
W
E
F
L
---------
K
E
K
F
F
E
L
V
V
P
Y
L
L
W
T
T
A
Y
L
-
W
L
F
P
A
V
QQQTP-YT
D
T
A
S
F
L
L
K
-
Y
VT---G-DGA
P
H
L
W
Y
T
V
M
M
L
Q
I
Q
L
F
M
P
F
F
V
W
L
-
G
Y
K
V
FANK
K
Y
V
W
P
V
LIG
S
T
I
L
Y
V
A
W
Y
L
F
Y
Q
T
Q
V
LTGP-YH
D
S
W
---
Y
L
L
D
R
F
V
A
S
F
M
I
Y
G
V
A
A
F
------
V
Y
H
E
K
V
Y
Q
Y
L
D
R
V
R
Y
L
F
------
L
P
V
A
L
V
I
A
-----------------------------
F
F
S
V
R
S
L
LAHPGDLSFA-----NA
P
Y
L
N
T
I
Q
S
L
Y
S
L
V
----------------
I
-
I
F
A
V
F
IGA
S
K
M
IVNDSPK----------------
L
P
-
L
F
K
W
L
S
-
V
Y
A
Y
R
T
Y
L
A
N
-
V
-----------
F
V
F
Q
V
L
L
L
L
F
K
D
S
-
W
------LQLP
S
G
V
M
I
L
V
A
Y
L
M
T
A
S
C
A
--
F
A
L
S
W
L
-------------
L
H
I
I
W
V
A
I
K
KGFSK------------------------------------------------------------
22
Fugue
71.73
14%
-53
* C3 *
-
4UM2
1
EST1A_HUMAN
A:
[1-582]
----------S
M
E
L
H
R
L
L
R
V
A
D
-----
N
Q
E
L
-
Q
L
S
N
L
L
S
R
D
R
I
S
P
E
G
L
E
K
M
A
Q
L
R
A
E
L
L
Q
L
Y
E
R
C
I
L
L
D
I
E
F
S
D
N
Q
N
V
D
Q
I
L
W
K
N
A
F
Y
Q
V
I
E
K
F
R
Q
L
V
K
DPNVEN
P
E
Q
I
R
N
R
L
L
E
L
L
D
E
G
S
D
F
F
D
S
L
L
Q
K
L
Q
V
T
Y
K
F
K
L
E
D
Y
M
DGLAIRLR
K
T
V
K
Y
A
L
I
S
A
Q
R
C
M
I
C
Q
G
D
I
-
A
R
Y
R
E
Q
A
S
D
T
A
N
Y
G
K
A
R
S
W
Y
L
K
-
A
Q
H
I
AP
K
-
N
G
R
P
Y
N
Q
L
A
L
L
A
V
Y
T
R
R
K
L
D
A
V
Y
Y
Y
-
M
R
S
L
A
A
S
N
----
P
I
L
T
A
K
E
S
L
M
S
L
F
E
E
T
K
R
K
A
E
Q
M
E
K
-
G
L
G
S
L
S
P
S
D
L
N
K
R
F
I
L
S
F
L
H
A
H
G
K
L
F
TRIGME
T
F
P
A
V
A
E
K
V
L
K
E
F
Q
V
L
L
Q
HSPSP
I
G
S
T
R
M
L
Q
-----------------------------
L
M
T
I
N
M
F
A
V
H
N
S
Q
R
S
V
I
-----
Q
E
Q
A
A
A
L
G
L
A
M
F
S
L
L
----------------
V
R
R
C
T
C
L
L
K
E
S
L
S
S
P
E
D
Q
D
D
----------------
Q
D
-
D
I
K
V
S
S
F
V
P
D
L
K
E
L
L
P
S
-
V
-----------
K
V
W
S
D
W
M
L
G
Y
P
D
T
-
W
NPPPTS
L
D
L
P
S
H
V
A
V
D
V
W
S
T
L
A
D
F
C
N
--
I
L
T
A
V
N
QSE
V
P
L
Y
KDPDDD
L
T
L
L
I
L
E
E
D
R
L
L
S
G
FVPLLAAPQ
D
P
C
Y
V
E
KTSD
K
V
I
A
A
D
C
K
R
V
T
V
L
K
Y
F
L
E
A
L
C
G
QEEPLLAFKGG
K
Y
V
S
VAPV
25
Fugue
50.61
16%
-44
- C3 -
-
4C0E
-
?
A:
[1674-2193]
L
E
A
A
H
L
L
E
Q
M
E
Y
V
F
D
E
W
I
H
L
C
N
NPHAT
E
R
A
A
M
I
F
V
H
Q
L
H
S
V
Q
L
V
T
N
R
D
E
F
L
L
F
L
R
H
A
L
D
K
S
-----
V
E
R
F
E
Q
G
I
H
S
G
A
S
I
A
E
S
F
Q
A
V
E
A
L
V
K
L
I
I
I
F
V
K
SHS
A
A
V
A
F
M
D
-------------
S
I
L
A
L
G
V
L
V
A
N
S
H
H
V
K
R
G
E
N
F
---------
N
Q
R
V
F
Y
R
F
F
A
L
L
L
H
E
V
G
L
L
A
G
H
F
S
K
S
H
Y
E
Q
I
-
I
L
N
F
A
A
R
L
F
D
M
R
P
N
---
L
L
P
G
F
A
C
A
W
A
G
L
V
--
S
H
R
A
F
L
P
V
I
L
G
L
P
D
E
K
G
W
A
P
F
T
K
L
L
E
Q
F
L
G
C
V
G
E
L
V
K
---
T
F
T
V
S
S
L
G
K
E
M
Y
H
A
A
L
---
K
I
L
I
V
L
Q
H
D
F
P
I
Y
L
D
K
---------
F
R
V
Q
L
C
Q
S
L
P
L
H
A
T
Q
L
------
V
N
L
I
L
A
A
I
PPNCNSLADPFQAGLKVDKIPDMK
E
R
P
P
T
A
F
D
S
A
G
L
L
R
E
A
G
L
L
D
I
L
E
R
M
L
Q
N
G
P
S
E
D
G
V
A
Q
I
N
H
A
I
N
KSTSFGYVPLGVN
R
R
L
-
I
D
A
V
V
A
R
F
A
E
F
A
I
N
R
A
S
S
RSDSAIFVAGA
N
D
I
K
T
L
Q
M
L
V
T
E
V
S
-
P
E
A
R
Y
Y
L
V
S
S
M
V
N
E
LRYPN
A
Y
T
N
Y
F
S
Q
A
L
L
D
I
F
G
H
D
M
S
------
D
P
E
E
N
L
V
R
E
Q
I
V
R
V
L
L
E
R
V
L
GY
W
P
Q
P
W
G
-------------
L
I
I
T
I
L
E
L
L
K
N
D
K
Y
LFFEL
P
F
I
K
A
T
P
E
V
A
E
R
F
T
A
L
A
R
S
AA----------------------------------
23
Fugue
47.92
14%
-144
- C1 -
-
1WZU
-
NADA_PYRHO
A:
[1-298]
-------------------
M
D
L
-----
V
E
E
I
-
L
R
L
K
E
E
R
N
A
I
I
L
A
H
N
Y
Q
L
-
P
E
V
Q
D
I
A
D
F
I
-----
G
D
S
L
E
L
A
R
R
A
T
R
V
D
--------------
A
D
V
I
------------------------
V
F
A
G
V
D
F
M
A
E
T
A
K
I
L
N
----------------
P
D
K
V
V
L
I
P
S
V
E
H
I
L
E
A
K
-
R
K
Y
P
N
A
P
------------
V
V
L
-
Y
V
N
---
S
-
T
------------------------------
A
E
A
K
A
Y
A
D
V
T
V
T
S
A
N
A
V
E
V
V
K
K
L
D
S
D
V
V
I
F
G
P
------------
D
K
N
L
A
H
Y
V
A
K
M
T
G
K
K
------
I
I
P
V
F
T
L
D
D
V
E
R
A
K
K
L
H
-------
P
N
A
K
L
M
I
-----------------------------
H
P
E
C
I
P
E
V
Q
E
K
A
D
I
I
A
S
-----
T
G
G
M
I
K
R
A
C
E
--
W
D
E
----------------
W
-
V
V
F
T
E
R
E
M
V
Y
R
L
R
K
L
Y
P
Q
----------------
K
K
-
F
Y
P
-----------
A
R
E
-
D
-----------
A
F
C
A
I
T
L
K
N
I
Y
E
S
-
L
------
K
D
M
K
Y
K
V
E
V
P
E
E
I
A
R
K
A
R
K
A
--
I
E
R
M
L
E
-------------
M
-------------------------------------------------------------------------
4
PsiBlast_PDB
46.54
30%
-344
- C2 -
-
3K1R
-
USH1C_HUMAN
A:
[21-62]
---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
A
-----
E
K
D
Y
L
Y
D
V
L
R
M
Y
H
Q
T
----------------
M
-
D
V
A
V
L
V
G
D
L
K
L
V
I
N
E
P
S
R
----------------
L
P
-
L
F
D
A
I
-----------------------------------------------------------------------------------------------------------------------------------------------------------------
5
PsiBlast_PDB
45.89
30%
-320
- C2 -
-
5F3X
-
USH1C_HUMAN
A:
[23-65]
---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
A
-----
E
K
D
Y
L
Y
D
V
L
R
M
Y
H
Q
T
----------------
M
-
D
V
A
V
L
V
G
D
L
K
L
V
I
N
E
P
S
R
----------------
L
P
-
L
F
D
A
I
-----------------------------------------------------------------------------------------------------------------------------------------------------------------
2
PsiBlast_PDB
43.14
33%
-297
- C2 -
-
2KBR
-
USH1C_HUMAN
A:
[21-59]
---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
A
-----
E
K
D
Y
L
Y
D
V
L
R
M
Y
H
Q
T
----------------
M
-
D
V
A
V
L
V
G
D
L
K
L
V
I
N
E
P
S
R
----------------
L
P
-
L
F
--------------------------------------------------------------------------------------------------------------------------------------------------------------------
1
PsiBlast_PDB
42.90
33%
-270
- C2 -
-
2KBQ
-
USH1C_HUMAN
A:
[21-59]
---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
A
-----
E
K
D
Y
L
Y
D
V
L
R
M
Y
H
Q
T
----------------
M
-
D
V
A
V
L
V
G
D
L
K
L
V
I
N
E
P
S
R
----------------
L
P
-
L
F
--------------------------------------------------------------------------------------------------------------------------------------------------------------------
3
PsiBlast_PDB
40.36
33%
-247
- C2 -
-
2LSR
-
USH1C_HUMAN
A:
[21-59]
---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
A
-----
E
K
D
Y
L
Y
D
V
L
R
M
Y
H
Q
T
----------------
M
-
D
V
A
V
L
V
G
D
L
K
L
V
I
N
E
P
S
R
----------------
L
P
-
L
F
--------------------------------------------------------------------------------------------------------------------------------------------------------------------
12
HHSearch
32.00
33%
-
- C2 -
-
2KYG
-
C:
[593-610]
--------------------
I
W
-----
K
K
A
E
-
E
A
V
N
E
V
K
R
Q
A
M
T
---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
24
Fugue
26.96
15%
-
* C2 *
-
5FUR
-
TAF8_HUMAN
L:
[172-197]
--------------------
Y
Q
-----
V
L
R
E
-
K
A
A
S
Q
R
R
D
V
E
R
A
L
T
R
F
M
A
K
T
-------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
16
Fugue
26.86
6%
-155
- C2 -
-
1TU3
-
RABE1_HUMAN
F:
[21-66]
---------------------
A
-----
Q
R
L
Q
-
T
E
L
D
V
S
E
Q
V
Q
R
D
F
V
K
L
S
Q
T
L
Q
V
Q
L
E
R
I
R
Q
-----
A
D
S
L
E
R
I
R
A
I
L
N
-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
17
Fugue
26.74
10%
-114
- C2 -
-
1XOU
-
?
B:
[2-85]
-------------------
G
I
V
-----
S
Q
T
R
-
N
K
E
L
L
D
K
K
I
R
S
E
I
E
A
I
K
K
I
I
A
E
F
D
V
V
K
E
S
-----
V
N
E
L
S
E
K
A
K
T
D
P
Q
A
A
E
K
L
N
K
L
I
E
G
Y
T
Y
G
E
E
R
K
------------------------
L
Y
D
S
A
L
S
K
I
E
K
L
I
E
T
L
-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
18
Fugue
25.17
17%
-35
- C2 -
-
1DPJ
-
IPA3_YEAST
B:
[2-30]
--------------------
T
D
-----
Q
Q
K
V
-
S
E
I
F
Q
S
S
K
E
K
L
Q
G
D
A
K
V
V
S
D
A
F
K
----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
13
HHSearch
23.40
17%
-416
- C2 -
-
2WW9
-
SC61G_YEAST
B:
[61-78]
-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
V
G
-
I
I
G
Y
A
I
K
L
I
H
-
I
-----------
P
I
R
Y
V
-----------------------------------------------------------------------------------------------------------------------------------
19
Fugue
22.26
17%
16
- C2 -
-
1G0V
-
IPA3_YEAST
B:
[3-31]
--------------------
T
D
-----
Q
Q
K
V
-
S
E
I
F
Q
S
S
K
E
K
L
Q
G
D
A
M
V
V
S
D
A
F
K
----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
9
HHSearch
21.37
16%
-178
- C2 -
-
2LAT
-
OST4_HUMAN
A:
[13-31]
-----------------------------------------------
M
L
G
V
S
L
F
L
L
V
V
L
Y
H
-----
Y
V
A
V
N
------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
7
HHSearch
21.32
14%
16
- C2 -
-
2NR5
2
?
A:
[4-36]
------------------
M
M
T
K
-----
K
E
R
I
-
A
I
Q
R
S
M
A
E
E
A
L
G
K
L
K
A
I
R
Q
L
C
------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
14
HHSearch
21.29
17%
-416
- C2 -
-
2WWA
-
SC61G_YEAST
B:
[61-78]
-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
V
G
-
I
I
G
Y
A
I
K
L
I
H
-
I
-----------
P
I
R
Y
V
-----------------------------------------------------------------------------------------------------------------------------------
20
Fugue
20.73
19%
-88
- C2 -
-
3PCQ
-
PSAM_THEEB
M:
[1-31]
------------------------------------------
M
A
L
T
D
T
Q
V
Y
V
A
L
V
I
A
L
L
P
A
-----
V
L
A
F
R
L
S
T
E
L
Y
K
-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
6
HHSearch
20.28
14%
56
- C2 -
-
2NR5
-
?
E:
[4-34]
------------------
M
M
T
K
-----
K
E
R
I
-
A
I
Q
R
S
M
A
E
E
A
L
G
K
L
K
A
I
R
Q
L
C
------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------