@TOME V2.3
(Mar 2018)
Ref.
-
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Doc.
Global output mode :
Sort entries by :
Atome Result
Tools Result
PDB occurence
Core Structure Cluster
Sequence Color type :
Secondary Structure
Hydrophobicity
Disulfide Bonds
TCoffee Identity Score
Uniprot annotation
Core Structure Cluster
Contacts with Ligands
Show alignment :
Atome selection
All alignments
Only Template with Ligand
Column output:
Score:
Atome Rank Value
Tools Score
Hide column
Alignment:
Sequence Identity (%)
Tcoffee Alignment Score
Hide column
3D Common Core:
Tito PKB Score
Verify3D Score
QMean Score
Hide column
Structural Clustering:
Cluster Num
3D-Jury Struct. Score
Hide column
Modeller Result :
Model Rank
QMean Score
Dfire Score
Dope Score
Errat Score
Verify3D Score
Modeller Score
Hide column
Complexes Modeling
Show Ligands of Templates
Complexes Affinity Score
Main Binding Site Identity
Hide column
Templates Information:
Uniprot entry
Cath class
Scop class
Smart class
Prosite class
Pfam class
EC Number
Taxonomy
Experiment Method
Hide column
Sequence & Result Tab:
PDB Template Sequence
Complexes Tab
Values color: [
Good
|
Correct
|
Middling
|
Bad
]
Sequence color :
Mutated
Helix
Strand
Conserved
Query sequence : I3TZ14: (2017-12-15 )
MFITKRRCKQMDLNKRQLQILVVLRNKNHWITSEELAEALGTNKKTIQTEIKNMLAIYEKKIIIQSNKRSGYFLESIESETKQQIIQEVTKHKIYSSMDFRASTIVTYLLFQKGYVSMQKIADIFFLSKTAVSLQIKTILRWIERNPKLELEVSSTKGLKIIAEENSKRIFLSLVGTETVIQHARFPQQISTIFSNIMPTVQKTLKEVLISYNYIVSGEDFIRFSRYLVLTILRREELLEKTNRYTLFIPMVETLTKKLSSELPYSFSNQEKQAIENRLLELNYLMINDEKNKEIEKNLRAFEQTIIRFLDLPVSLLFHETEFLLTHIKQMKTRMDAGHNTMNHFVQKIISRYPLEIYLIRRFFPIHFQLRPNLAESAYFVLYLAEALNPFRKQGEILIVSNQPISILNTLKKQIQQSMNMWIKECRIEPVYLFKNQSNKITEYDAILTTEQELIFEWDDLIYLPSVLDEFESWEIYQILREKLTIVEEKKKTKLLDHYYKEENQIKIHKKIDSIQQLISPSSDLVMLPLNAETLLCCLIKSQVETKITEYQLEIPLIHQQRKIKRVFFVSFDYKRNDILVFFQAVSDLLG
Atome Classification :
(20 SA)
-------------------------------------------------------------------------.........10........20........30.........40........50.......---.60........70..-......80----.........90........100.......110.......120.......130.......140....-...150..----.....160......-----.170.......180.......190...-.----.------------..200.......210--........220.......-230...---------...--.240..--.---...---..250..-------.....260.-......270..-.....280....-..-.-------290.......300...---....310.......320.....--..330-........--340---.-........350...---....360.....---.---.------370....--...380-------.......390-.......400.......410.......420.-..-.-.---..--.430.......440--........450..--.----------....460....--...-.470...-....480.......490.......500.......510.....-----..520.......530....--------...540-.......550.......560-.------.......570.......580.......590-
(Atome)
(Ident)
(Tito)
(Num)
(QMean)
(Ligand)
(Uniprot)
-------------------------------------------------------------------------MFI
T
K
R
R
C
K
QMDLNK
R
Q
L
Q
I
L
V
V
L
RNKNHW-I
T
S
E
E
L
A
E
A
LGTN
K
K
T
I
Q
T
E
I
K
N
M
L
A
I
Y
---
E
K
K
I
I
I
Q
SNKRS
G
Y
F
-
L
E
S
I
E
S
E
-----
T
K
Q
Q
I
I
Q
E
V
T
K
H
K
I
YSSMD
F
R
A
S
T
I
V
T
Y
L
L
F
Q
KG
Y
V
S
M
Q
K
I
A
D
I
F
F
L
SK
T
A
V
S
L
Q
I
K
T
I
L
R
W
I
ERN-P
K
L
E
L
E
VS----STK
G
L
K
I
I
A
EENS
K
-----
R
I
F
L
S
LVG
T
E
T
V
I
Q
HAR
F
P
Q
Q
I
S
T
I
F
S
-
N
----
I
------------
M
P
T
V
Q
K
T
L
K
E
V
L
I
S---Y
N
Y
I
VSG
E
D
F
I
R
F
S
R
Y
L
V
-
L
T
I
L
R
R
---------
E
E
L
--
L
E
K-TN--
R
---
Y
T
L
---
F
I
P
M
V
E
T
-------
L
T
K
K
L
S
S
EL-PYSFS
N
Q
E
K
Q
A
-
I
E
N
R
L
L
E
L
N
Y
L
M
-IN-D-------EK
N
K
E
I
E
K
N
L
R
A
F
E
Q
T
---
I
I
R
F
L
DL
P
V
S
L
L
F
H
E
T
E
F
L
L
T
H
--
I
K
Q
M
--
K
T
R
MDAGH--
N
-----
T
-
M
N
H
F
V
Q
K
I
I
S
RY
P
L
---
E
I
Y
L
I
R
R
F
F
P
I
H
---
F
---
Q
------LRPNLAE--
S
A
Y
F
V
L
-------
Y
L
A
E
A
L
N
P
F
R
-KQG
E
I
L
I
VSNQ
P
I
S
I
L
N
T
L
K
K
Q
I
Q
Q
S
M
N
M
-
W
-
I
K
-E-C---RI--E
P
V
Y
L
FKNQSNKI---TE
Y
D
A
I
LT
T
E
Q
E
L
--
I
----------FEWDD-
L
I
Y
L
P
--
S
V
L
-
D
EFES
W
E
-
I
Y
Q
I
L
R
E
K
L
T
I
V
E
E
K
K
K
T
K
L
L
D
H
Y
YKEEN
Q
I
K
I
H
K
K
I
D
S
I
Q
Q
-----
L
ISPSS
D
L
V
M
L
PL
N
A
E
T
L
L
--------
C
C
L
I
K
S
-
Q
V
E
TKI
T
E
Y
Q
L
EI
P
L
I
H
Q
Q--R------
K
I
K
R
V
F
F
V
S
F
DYKRN
D
I
L
V
F
F
Q
A
V
S
D
L
LG--
9
HHSearch
81.06
17%
-53
- C3 -
-
4R6I
1
ATXA_BACAN
B:
[14-476]
--------------------------------------------------------------------------------------
H
I
R
L
I
N
L
L
H
F
I
N
E
Q
N
R
W
-
F
T
I
K
E
L
S
D
Y
L
Q
V
A
D
K
T
V
R
K
Y
L
K
L
L
E
D
E
I
---
P
P
S
W
N
L
L
V
Q
K
G
K
G
I
Y
-
L
K
K
P
L
N
E
-----
S
L
S
F
V
E
-------
S
K
I
L
R
K
S
L
N
L
Q
I
C
E
E
L
V
F
-
K
K
-
N
S
M
Q
S
L
A
Q
K
L
H
L
Q
V
G
A
L
Y
P
I
I
N
Q
I
N
Y
D
I
Q
-
S
-
S
H
L
N
I
K
K
-------
K
P
L
E
I
S
G
R
E
Q
D
V
-----
R
V
F
M
L
R
L
Y
C
N
I
P
-
N
D
-------
Y
W
P
F
P
Y
I
----
N
------------
K
Q
N
I
T
D
L
I
N
K
M
E
K
I
---
L
N
V
Q
M
Y
T
Y
S
K
H
K
L
C
V
L
F
A
-
I
T
I
S
R
L
---------
L
S
G
NT
I
D
N
V
S
G
LI
L
VNK
N
D
D
---
H
Y
K
T
V
A
S
-------
I
T
S
E
L
Q
N
S
F
-
G
V
T
L
H
E
T
E
I
S
F
-
L
A
L
A
L
L
L
S
L
G
N
S
I
T
--
N
K
T
L
T
---
S
Y
K
K
T
I
M
P
L
A
K
E
I
T
K
G
---
I
E
H
K
L
Q
L
G
I
N
Y
D
E
S
F
L
T
Y
V
V
L
I
--
I
K
K
A
--
L
D
K
N
F
I
Q
Y
--
Y
-----
N
Y
N
I
K
F
I
R
H
I
K
Q
R
H
P
N
---
T
F
N
T
I
Q
E
C
I
S
N
L
NYT
V
---
Y
------
S
H
F
D
C
Y
E
--
I
S
L
L
T
M
-------
H
F
E
T
Q
R
M
L
F
K
N
N
P
K
K
I
Y
V
Y
T
S
Q
G
C
I
H
R
E
Y
I
S
A
L
L
E
K
R
Y
N
G
-
L
-
I
K
-
I
-
V
---
R
N
---
T
I
---------
D
---
M
E
I
D
I
I
I
S
N
------------------------------
E
F
P
-
T
E
R
D
F
H
E
-
I
K
K
-----------------------------------------------------------------------------------------------------------------------------------------
11
HHSearch
65.14
13%
-36
- C3 -
-
5WAY
1
?
B:
[9-492]
--------------------------------------------------------------------------------------
S
H
R
Q
L
E
L
L
E
L
L
F
E
H
K
R
W
-
F
H
R
S
E
L
A
E
L
L
N
C
T
E
R
A
V
K
D
D
L
S
H
V
K
S
A
F
---
P
D
L
-
I
F
-
H
------
R
-
I
I
N
T
D
D
S
-----
D
I
E
M
V
Y
H
-------
H
F
F
K
H
S
T
H
F
S
I
L
E
F
I
F
F
-
N
E
G
C
Q
A
E
S
I
C
K
E
F
Y
I
S
S
S
S
L
Y
R
I
I
S
Q
I
N
K
V
I
K
-
R
Q
F
Q
F
E
V
S
L
-------
T
P
V
Q
I
I
G
N
E
R
D
I
-----
R
Y
F
F
A
Q
Y
F
S
E
K
Y
Y
F
L
-------
E
W
P
F
E
N
F
----
S
------------
S
E
P
L
S
Q
L
L
E
L
V
Y
K
E
---
T
S
F
P
M
N
L
S
T
H
R
M
L
K
L
L
L
V
-
T
N
L
Y
R
I
---------
K
F
G
HF
M
E
V
----------
L
D
F
L
M
Q
A
E
G
I
E
G
-------
V
A
Q
S
F
E
S
E
Y
-
N
I
S
L
D
E
E
V
V
C
Q
-
L
F
V
S
Y
F
Q
K
M
F
F
I
D
E
S
L
F
M
K
C
V
K
K
D
S
Y
V
E
K
S
Y
H
L
L
S
D
F
I
D
Q
---
I
S
V
K
Y
Q
I
E
I
E
N
K
D
N
----
L
I
W
H
--
L
H
N
T
A
H
L
Y
R
Q
E
L
F
T
--
E
FILFD
Q
-
K
G
N
T
I
R
N
F
Q
N
I
F
P
K
---
F
V
S
D
V
K
K
E
L
S
H
Y
---
L
E
T
L
E
------
V
C
S
S
S
M
M
--
V
N
H
L
S
Y
T
F
I
T
H
TK
H
L
V
I
N
L
L
Q
N
Q
-
P
K
L
K
V
L
V
M
S
N
F
D
Q
Y
H
A
K
F
V
A
E
T
L
S
Y
Y
C
S
N
-
N
-
F
E
---
L
---
E
V
--
W
T
E
L
E
L
S
K
E
S
L
E
D
---
S
P
Y
D
I
I
I
S
N
F
I
I
P
P-
I
----------
E
-
N
K
R
-
L
I
Y
S
N
--
N
I
N
-
T
V
S
L
I
Y
L
-
L
N
A
M
M
F
I
R
L
D
----------------------------------------------------------------------------------------------------------------------------------
12
HHSearch
64.60
13%
-33
- C3 -
-
5WAY
1
?
A:
[9-493]
--------------------------------------------------------------------------------------
S
H
R
Q
L
E
L
L
E
L
L
F
E
H
K
R
W
-
F
H
R
S
E
L
A
E
L
L
N
C
T
E
R
A
V
K
D
D
L
S
H
V
K
S
A
F
---
P
D
L
-
I
F
-
H
S
S
T
N
G
I
R
-
I
I
N
T
D
D
S
-----
D
I
E
M
V
Y
H
-------
H
F
F
K
H
S
T
H
F
S
I
L
E
F
I
F
F
-
N
E
G
C
Q
A
E
S
I
C
K
E
F
Y
I
S
S
S
S
L
Y
R
I
I
S
Q
I
N
K
V
I
K
-
R
Q
F
Q
F
E
V
S
L
-------
T
P
V
Q
I
I
G
N
E
R
D
I
-----
R
Y
F
F
A
Q
Y
F
S
E
K
Y
Y
F
L
-------
E
W
P
F
E
N
F
----
S
------------
S
E
P
L
S
Q
L
L
E
L
V
Y
K
E
---
T
S
F
P
M
N
L
S
T
H
R
M
L
K
L
L
L
V
-
T
N
L
Y
R
I
---------
K
F
G
HF
M
E
V
------------FLM
Q
A
E
G
I
E
G
-------
V
A
Q
S
F
E
S
E
Y
-
N
I
S
L
D
E
E
V
V
C
Q
-
L
F
V
S
Y
F
Q
K
M
F
F
I
D
E
S
L
F
M
K
C
V
K
K
D
S
Y
V
E
K
S
Y
H
L
L
S
D
F
I
D
Q
---
I
S
V
K
Y
Q
I
E
I
E
N
K
D
N
----
L
I
W
H
--
L
H
N
T
A
H
L
Y
R
Q
E
L
F
T
--
E
FILFD
Q
-
K
G
N
T
I
R
N
F
Q
N
I
F
P
K
---
F
V
S
D
V
K
K
E
L
S
H
Y
---
L
E
T
L
E
------
V
C
S
S
S
M
M
--
V
N
H
L
S
Y
T
F
I
T
H
TK
H
L
V
I
N
L
L
Q
N
Q
-
P
K
L
K
V
L
V
M
S
N
F
D
Q
Y
H
A
K
F
V
A
E
T
L
S
Y
Y
C
S
N
-
N
-
F
E
---
L
---
E
V
--
W
T
E
L
E
L
S
K
E
S
L
E
D
---
S
P
Y
D
I
I
I
S
N
F
I
I
P
P-
I
----------
E
-
N
K
R
-
L
I
Y
S
N
--
N
I
N
-
T
V
S
L
I
Y
L
-
L
N
A
M
M
F
I
R
L
D
E
---------------------------------------------------------------------------------------------------------------------------------
1
PsiBlast_PDB
61.70
22%
-187
- C3 -
-
5WAY
-
?
A:
[25-171]
------------------------------------------------------------------------------------------------------
W
-
F
H
R
S
E
L
A
E
L
L
N
C
T
E
R
A
V
K
D
D
L
S
H
V
K
S
A
F
----
P
D
L
I
F
H
S
S
T
N
G
I
R
I
-
I
N
T
D
D
S
D
----------
I
E
M
V
Y
H
H
F
F
K
H
S
T
H
F
---
S
I
L
E
F
I
F
F
N
E
G
-
C
Q
A
E
S
I
C
K
E
F
Y
I
S
S
S
S
L
Y
R
I
I
S
Q
I
N
K
V
I
K
R
---
Q
F
Q
F
E
V
S
----
L
T
P
-
V
Q
I
I
G
N
E
R
D
I
-----
R
Y
F
F
A
Q
Y
F
S
E
-------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
37
Fugue
56.77
13%
24
- C1 -
-
4KVM
-
NAT1_SCHPO
A:
[5-731]
QLS
P
K
E
I
T
L
F
R
T
A
L
K
C
Y
E
T
KQY
K
K
G
L
K
A
I
EPLLERHPEH
G
E
S
L
A
I
K
G
I
L
L
H
S
LGNT
K
E
G
Y
D
N
V
R
L
G
L
R
N
D
VGS
G
V
C
W
H
I
F
G
L
I
S
R
A
D
K
D
Y
V
Q
A
A
K
C
Y
I
N
A
H
K
L
E
K
N
N
S
S
L
L
R
D
L
A
L
L
Q
S
Q
L
R
-
Q
Y
K
A
L
A
D
T
R
---
N
A
L
L
Q
D
N
P
G
V
R
A
N
W
S
-
A
L
A
V
A
Q
F
L
R
GE
Y
A
S
A
Y
K
I
V
D
A
F
E
S
T
I
N
Q
G
V
P
V
D
T
Q
E
E
S
E
A
M
L
F
M
N
L
V
I
L
K
K
D
G
V
E
D
A
Y
K
H
L
L
S
I
E
K
K
V
L
D
R
V
A
F
L
E
T
R
-
A
E
Y
E
L
Y
L
S
K
M
E
E
A
K
S
T
I
Y
L
L
L
D
R
N
P
D
N
H
Q
Y
Y
Y
N
L
Q
R
A
Y
G
Y
E
D
A
S
G
K
V
L
D
S
A
E
W
L
N
L
Y
S
-
Q
----
L
------------
A
K
R
Y
P
K
S
E
C
P
T
R
L
P
---
L
E
K
L
-
E
G
D
E
F
L
T
H
V
D
L
Y
L
-
R
K
K
L
K
R
GIPS
V
F
V
D
V
K
S
L
--
Y
K
D
-
T
K
--
K
---
C
K
V
---
V
E
D
L
V
S
K
-------
Y
A
S
S
L
S
T
T
N
-
K
F
S
E
D
D
D
N
S
Q
I
E
I
P
T
T
L
L
W
T
Y
Y
F
L
-
A
Q
-
H
-------
F
D
H
V
G
E
L
E
K
A
E
K
Y
V
D
L
---
A
I
D
H
T
P
T
L
V
E
L
F
M
T
K
A
R
I
S
K
H
K
GE
L
Q
T
A
--
M
E
I
M
D
H
A
R
K
L
D
-----
L
-
Q
D
R
F
I
N
G
K
C
A
K
Y
M
L
R
N
D
E
N
E
L
A
A
K
T
V
S
L
F
---
T
---
R
NEAVGG
A
V
G
D
L
A
D
M
Q
C
L
W
Y
M
L
-------
E
D
G
K
S
F
A
R
Q
K
-
K
F
A
L
A
L
K
R
F
S
T
V
F
K
I
F
D
T
W
A
D
D
Q
F
D
F
H
F
F
-
A
-
F
R
-
K
-
G
---
S
L
--
R
T
Y
L
D
L
M
S
W
E
D
S
V
YDD
P
S
F
R
E
A
A
Q
G
S
I
E
I
--
Y
----------
F
A
L
F
D
-
L
P
F
A
K
YS
P
K
L
-
P
D
F
E
K
L
S
-
S
G
E
I
N
E
E
E
E
K
K
I
Y
K
K
L
K
K
D
L
S
K
R
L
E
R
A
E
K
L
K
E
A
D
K
S
R
K
Y
D
E
D
PLGEN
L
V
A
T
S
E
P
L
K
E
A
Q
K
C
L
E
K
L
L
P
Y
GDKNP
S
A
Y
I
L
A
A
-
Q
L
Y
T
R
L
K
N
F
D
T
A
S
K
Y
L
E
Q
A
--
K
------
V
I
L
G
----
Q
N
D
P
T
V
I
S
T
E
K
F
Y
N
S
I
K
T
Q
S
N
AA
41
Fugue
53.31
19%
-6
- C2 -
-
4WW4
1
?
A:
[3-458]
-------------------------------------------------------------------------------
Q
I
S
E
V
R
G
N
T
R
D
H
------
R
T
A
A
H
------
T
H
I
K
G
L
G
L
N
S
S
G
I
---------------------
A
E
K
Q
A
A
G
F
-
V
G
Q
C
A
A
R
-----
E
A
C
G
V
V
V
D
L
I
K
A
H
K
M
A
G
---------
R
G
V
L
L
A
G
G
P
G
T
----------
G
K
T
A
L
A
L
A
I
S
Q
E
L
------------------------------
G
T
K
-----
I
P
F
C
P
I
T
G
S
E
I
Y
S
T
E
V
K
K
T
E
V
L
M
E
N
F
R
-
R
----
A
------------
I
G
L
R
V
R
E
T
K
D
V
Y
E
----------
G
E
V
----
S
T
L
L
I
G
L
K
S
A
R
G
---------
Q
K
L
--
D
Q
K
-
E
R
--
V
---
Q
V
G
---
D
V
I
Y
I
E
T
-------
N
T
G
A
C
R
S
D
A
Y
A
T
E
F
D
L
E
A
E
E
Y
-
V
P
I
P
K
G
E
V
----------------
H
K
K
K
E
I
V
Q
D
V
T
L
H
D
L
D
---
V
A
N
A
R
P
D
I
I
S
M
M
G
Q
L
M
K
--------
P
K
M
--
T
E
I
T
D
K
L
R
--
M
-----
E
-
I
N
K
V
V
Q
K
Y
I
N
Q
G
V
A
---
E
L
I
P
--------------------------------
G
V
L
F
I
-------
D
E
A
H
M
L
D
----------------
I
E
C
F
T
Y
L
N
K
A
L
E
S
P
I
A
P
-----------------
I
V
V
L
A
S
N
R
G
I
A
T
---
I
R
G
A
D
D
L
K
A
A
H
G
I
--
P
----------
P
D
F
L
Q
R
L
L
I
I
P
--
T
---
H
P
Y
E
P
D
E
-
I
R
R
I
V
R
I
R
A
Q
T
E
G
V
Q
L
T
D
A
A
V
D
R
V
A
E
H
G
V
R
I
S
----
L
R
Y
C
L
Q
-----
L
L
A
P
A
S
I
L
A
R
V
N
G
------------------
R
T
-
Q
V
D
---------------
V
--
Q
------
D
I
A
E
A
E
E
L
F
L
D
A
R
R
S
A
N
I
L
T
S
---
T
G
G
L
H
--
33
Fugue
51.26
23%
-150
- C3 -
-
1BIA
-
?
?:
[1-88]
-----------------------------------------------------------------------------------
M
K
D
N
T
V
P
L
K
L
I
A
L
L
A
N
-
G
E
F
-
H
S
G
E
Q
L
G
E
T
L
G
M
S
R
A
A
I
N
K
H
I
Q
T
L
R
D
------
W
G
V
D
V
F
T
V
P
G
K
G
Y
S
-
L
P
E
P
---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
39
Fugue
44.84
21%
-55
- C3 -
-
1FSE
-
GERE_BACSU
A:
[8-74]
-------------------------------------------------------------------------------
S
K
P
--
L
L
T
K
R
E
R
E
V
F
E
L
L
V
Q
D
K
----
T
T
K
E
I
A
S
E
L
F
I
S
E
K
T
V
R
N
H
I
S
N
A
M
Q
K
L
GVK
G
R
S
Q
A
V
V
E
L
L
R
M
G
E
L
-
E
L
-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
38
Fugue
41.70
21%
-60
- C3 -
-
1FSE
-
GERE_BACSU
A:
[8-74]
---------------------------------------------------------------------------------
S
K
P
L
L
T
K
R
E
R
E
V
F
E
L
L
V
Q
D
K
----
T
T
K
E
I
A
S
E
L
F
I
S
E
K
T
V
R
N
H
I
S
N
A
M
Q
K
L
GVK
G
R
S
Q
A
V
V
E
L
L
R
M
G
E
L
-
E
L
-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
17
HHSearch
37.98
13%
-8
- C- -
-
3CZC
-
?
A:
[1-92]
---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
M
V
K
V
L
T
A
C
G
N
G
M
G
S
S
M
V
I
K
M
K
V
E
N
A
L
R
Q
L
G
-
V
S
-
D
-
I
---
E
S
A
S
C
S
V
G
E
A
K
---
G
L
A
---
S
N
Y
D
I
V
V
A
S
N
H
L
I
H-
E
LDGR------
T
-
N
G
K
-
L
I
G
L
D
--
N
L
M
-
D
D
N
E
I
K
T
K
L
E
E
A
L
---------------------------------------------------------------------------------------------------------------------------------------
35
Fugue
37.74
18%
-61
- C3 -
-
4J2N
-
?
A:
[3-56]
---------------------------------------------------------------------------------------------------
M
P
P
R
-
A
S
I
Q
Q
T
A
D
Y
L
G
V
S
T
K
T
V
R
N
Y
I
A
A
--------
G
K
L
K
A
V
R
L
G
P
R
L
I
R
V
E
R
D
S
V
E
A
L
-----
M
R
P
I
---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
31
HHSearch
37.66
18%
-136
- C3 -
-
3T43
-
?
A:
[46-96]
------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
G
V
A
I
P
------
H
--------
T
D
-
S
K
Y
-
V
R
Q
N
A
I
S
V
G
I
L
A
E
P
V
N
F
E
D
A-
G
GEPDPV
P
V
R
V
V
F
M
L
A
L
G
N
W
------------------
18
HHSearch
36.81
10%
-92
- C3 -
-
1TVM
-
PTKB_ECOL6
A:
[20-111]
--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
S
K
R
K
I
I
V
A
C
G
G
A
V
A
T
S
T
M
A
A
E
E
I
K
E
L
C
Q
S
---
H
N
-
I
-
P
V
E
L
I
Q
--
C
R
V
N
E
I
E
---
T
Y
M
---
D
G
V
H
L
I
C
T
T
A
R
V
D
R-
S
----------
F
G
D
I
P
-
L
V
H
G
M
--
P
F
V
-
S
G
V
G
I
E
A
-
L
Q
N
K
I
L
T
I
L
-----------------------------------------------------------------------------------------------------------------------------------
5
PsiBlast_PDB
34.76
23%
-61
- C4 -
-
5XEI
-
?
A:
[99-250]
------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
E
V
V
I
K
R
R
V
Y
P
D
G
R
S
A
Y
W
L
-
N
GRRA
T
------------
R
S
E
I
L
D
L
L
S
A
A
M
I
S
PEG
Y
N
L
V
L
Q
G
D
----
I
T
K
F
I
K
-
M
S
P
L
E
R
---------
R
Q
L
--
I
D
E
-
I
S
--
G
---
I
A
E
---
Y
D
A
K
K
E
K
-------
A
L
E
E
L
-------------
K
Q
A
-
E
E
N
-
L
A
R
V
D
L
L
I
---------------
K
E
V
K
K
Q
L
D
K
L
E
K
E
R
N
D
A
L
R
Y
L
D
L
K
E
R
L
E
R
A
R
V
A
L
L
L
G
E
--
I
K
R
L
--
E
S
M
I
D
E
G
---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
21
HHSearch
34.66
12%
-44
- C3 -
-
2L2Q
-
?
A:
[4-104]
---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
S
M
N
I
L
L
V
C
G
A
G
M
S
T
S
M
L
-
V
Q
R
I
E
K
Y
A
K
S
-
K
N
I
N
-
A
T
I
---
E
A
--
I
A
E
T
R
L
S
---
E
V
V
---
D
R
F
D
V
V
L
L
A
P
Q
S
R
F-
N
K
K
R
L
E
E
I
T
K
P
K
-
G
I
P
-
I
E
I
I
N
T
I
D
Y
G
-
T
-
M
N
G
E
K
-
V
L
Q
L
A
I
N
A
F
N
----------------------------------------------------------------------------------------------------------------------------------
16
HHSearch
34.17
15%
-43
- C3 -
-
5GQS
-
?
A:
[2-90]
----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
K
Q
V
L
V
A
C
G
A
G
I
A
T
S
T
V
V
N
N
A
I
E
E
M
A
K
E
-
H
N
I
K
V
D
-
I
---
K
Q
--
I
K
I
T
E
V
G
---
P
Y
E
---
D
T
A
D
L
L
V
T
T
A
M
T
K
K-
E
----------
Y
-
K
F
P
-
V
I
N
A
R
--
N
F
L
-
T
G
I
G
I
E
E
-
T
K
Q
Q
I
L
T
E
L
-----------------------------------------------------------------------------------------------------------------------------------
28
HHSearch
34.03
19%
-122
- C3 -
-
2OQ3
-
PTMA_ECOLI
A:
[62-107]
------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
G
V
A
M
P
------
H
--------
A
R
-
P
E
C
G
A
L
K
T
G
M
S
L
T
L
L
E
Q
G
V
Y
F
P
G
ND
E
------
P
I
K
L
L
I
G
L
S
A
A
D
-------------------
6
PsiBlast_PDB
33.81
21%
65
- C4 -
-
1Z6A
-
?
A:
[244-384]
---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
T
K
Y
D
K
A
I
I
N
D
L
P
D
-----
K
I
E
T
N
V
Y
C
N
L
T
P
E
Q
A
A
M
Y
K
A
E
V
E
N
L
F
N
-
N
----
I
DSVTGI
K
R
K
G
M
I
L
S
T
L
L
K
-
L
K
Q
I
V
D
H
---
P
A
L
L
K
G
G
E
Q
S
V
R
R
S
G
K
M
I
-
R
T
M
E
I
I
---------
E
E
A
--
L
D
E
-
G
D
--
K
---
I
A
I
---
F
T
Q
F
V
D
M
G
K
I
I
R
N
I
I
E
K
E
L
N
T
E
V
-
P
F
L
Y
G
E
L
S
K
K
-------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
36
Fugue
33.50
11%
-81
- C3 -
-
1XMK
-
A:
[1-79]
-----------------------------------------------------------------------------
G
S
H
M
A
S
L
D
M
A
E
I
K
E
K
I
C
D
Y
L
F
N
V
S
D
--
S
S
A
L
N
L
A
K
N
I
G
--
L
T
K
A
R
D
I
N
A
V
L
I
D
M
E
---
R
Q
G
D
V
Y
R
Q
G
T
T
P
P
I
W
-
H
L
T
D
K
K
R
-----
E
R
M
Q
I
K
-------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
22
HHSearch
33.09
9%
-41
- C3 -
-
4MGE
-
?
B:
[1-101]
----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
M
N
I
L
L
C
C
S
A
G
M
S
T
S
L
L
V
T
-
K
M
E
A
A
A
K
A
-
R
G
L
E
G
K
-
I
---
W
A
--
V
S
G
D
A
V
K
---
T
N
I
---
D
Q
A
D
V
L
L
L
G
P
Q
V
R
YM
L
SSMKTLADE-
R
-
N
V
G
-
I
D
V
I
N
--
P
M
H
Y
G
M
M
N
G
E
A
-
V
L
D
H
A
L
T
L
K
K
G
---------------------------------------------------------------------------------------------------------------------------------