@TOME V2.3
(Mar 2018)
Ref.
-
-
Doc.
Global output mode :
Sort entries by :
Atome Result
Tools Result
PDB occurence
Core Structure Cluster
Sequence Color type :
Secondary Structure
Hydrophobicity
Disulfide Bonds
TCoffee Identity Score
Uniprot annotation
Core Structure Cluster
Contacts with Ligands
Show alignment :
Atome selection
All alignments
Only Template with Ligand
Column output:
Score:
Atome Rank Value
Tools Score
Hide column
Alignment:
Sequence Identity (%)
Tcoffee Alignment Score
Hide column
3D Common Core:
Tito PKB Score
Verify3D Score
QMean Score
Hide column
Structural Clustering:
Cluster Num
3D-Jury Struct. Score
Hide column
Modeller Result :
Model Rank
QMean Score
Dfire Score
Dope Score
Errat Score
Verify3D Score
Modeller Score
Hide column
Complexes Modeling
Show Ligands of Templates
Complexes Affinity Score
Main Binding Site Identity
Hide column
Templates Information:
Uniprot entry
Cath class
Scop class
Smart class
Prosite class
Pfam class
EC Number
Taxonomy
Experiment Method
Hide column
Sequence & Result Tab:
PDB Template Sequence
Complexes Tab
Values color: [
Good
|
Correct
|
Middling
|
Bad
]
Sequence color :
Mutated
Helix
Strand
Conserved
Query sequence : Q3XWP5: (2017-12-31 )
MYDQLQAIEDRYEELGELLSDPEVISDTKRFMQLSKEEANTRETVEVYRRYKEVVQGITDTEELLGEKLDDEMAELAKEELSELKKEKEVLEEKIKILLLPKDPNDDKNIIMEIRGAAGGDEAALFAGDLFNMYQKYAEAQGWKTEVMEANVTGIGGYKEVIMMITGDNVYSKLKYESGAHRVQRVPSTESQGRIHTSTATVVVMPEAEEVEIDIEDKDIRTDIYHASGAGGQHVNKTASAVRLTHLPTGIVVAMQDERSQIKNREKAMKILRARVYDKIQQEAQSEYDANRKSAVGTGDRSERIRTYNFPQNRVTDHRIGLTIQKLDQILAGKLDEIVDALIMYDQTSKLEAMQNG
Atome Classification :
(20 SA)
-------------------.........10........20........30........40........50.........60........70........80........90........--100.---...---....110.......120.......130..-......140.......150.......160.......170.......180.......190.......200.......210..-......220.......230.......240...---------------------.------..------------------.---250-.........260......-.270-.......280........-290.........300.......310.......320.......330.......340.......350.....
(Atome)
(Ident)
(Tito)
(Num)
(QMean)
(Ligand)
(Uniprot)
-------------------MY
D
Q
L
Q
A
I
E
D
R
Y
E
E
L
G
E
L
LSDP
E
V
I
S
D
T
K
R
F
M
Q
L
S
K
EEAN
T
R
E
T
V
E
V
Y
R
R
-
Y
K
E
V
V
QGIT
D
T
E
E
L
L
G
E
K
L
D
D
E
M
A
E
L
A
K
E
E
L
S
E
L
K
K
E
K
E
V
L
E
EK
I
K
I
L
L
--
L
-PK---DPN---DDK
N
I
I
M
E
I
RGAAGGD
E
A
A
L
F
A
G
D
L
-
F
N
M
-
Y
Q
K
Y
A
E
AQGW
K
T
E
V
M
E
ANVTGIG
G
Y
K
E
V
I
M
M
I
TGD
N
V
Y
S
K
LKYESGA
H
R
V
QRVPSTESQ
G
R
I
HT
S
T
A
T
V
V
V
MPEA
E
E
-
V
E
I
-
D
IEDKDI
R
T
D
I
Y
HASGAGGQHVNKTA
S
A
V
R
L
T---------------------H------LP------------------T---
G
---
I
V
V
A
MQ
D
E
R
S
Q
I
K
N
R
E
K
A
-
M
K
I
L
-
R
A
R
V
Y
D
K
I
-
Q
Q
E
A
Q
S
EYD-A--NRKSAVGTGD
R
S
E
R
I
R
TYNFPQNRVTDHRI
G
L
T
I
Q
K
L
D
Q
I
L
A
G
K
L
D
E
I
V
D
A
L
I
MYDQTS
K
L
E
AMQNG
15
HHSearch
82.38
75%
-52
- C8 -
-
1ZBT
-
RF1_STRMU
A:
[5-358]
---------------------
D
Q
L
Q
A
V
E
D
R
Y
E
E
L
--------------------
R
E
E
A
N
S
R
E
T
V
A
V
Y
R
E
-
Y
K
Q
V
V
Q
N
I
A
D
A
Q
E
M
------
P
E
L
E
E
M
A
K
E
E
L
K
N
S
K
V
A
K
E
E
Y
E
E
K
L
R
F
L
L
--
L
-
P
K
---
D
P
N
---
D
D
K
N
I
I
L
E
I
R
G
A
A
G
G
D
E
A
A
L
F
A
G
D
L
-
L
N
M
-
Y
Q
K
Y
A
E
N
Q
G
W
K
F
E
V
M
E
A
S
A
N
G
V
G
G
L
K
E
V
V
A
M
V
S
G
Q
S
V
Y
S
K
L
K
Y
E
S
G
A
H
R
V
Q
R
V
P
V
T
E
S
Q
G
R
V
H
T
S
T
A
T
V
L
V
M
P
E
V
E
E
-
V
E
Y
-
E
I
D
P
K
D
L
R
V
D
I
Y
H
A
---------
K
V
A
T
A
V
R
I
I
---------------------
H
------
L
P
------------------
T
---
N
---
I
K
V
E
M
Q
E
E
R
T
Q
Q
K
N
R
D
K
A
-
M
K
I
I
-
R
A
R
V
A
D
H
F
-
A
Q
I
A
Q
D
E
Q
D
-
A
------
T
V
G
T
G
D
R
S
E
R
I
R
T
Y
N
F
P
Q
N
R
V
T
D
H
R
I
G
L
T
L
Q
K
L
D
S
I
L
S
G
K
L
D
E
V
I
D
A
L
I
L
Y
D
Q
T
Q
K
L
E
E
L
N
--
5
PsiBlast_PDB
71.07
35%
0
- C- -
-
1ML5
-
RF2_ECOLI
Z:
[24-359]
--------------------
Y
L
D
Y
D
A
K
K
E
R
L
E
E
V
N
A
E
L
E
Q
P
D
V
W
N
E
P
E
R
A
Q
A
L
G
K
E
R
S
S
L
E
A
V
V
D
T
L
D
Q
-
M
K
---
Q
G
L
E
D
V
S
G
L
L
E
L
A
V
E
A
D
D
E
E
T
F
N
E
A
V
A
E
L
----
D
A
L
E
E
K
L
A
Q
L
E
--
F
-
R
R
MFS
G
E
Y
---
D
S
A
D
C
Y
L
D
I
Q
A
G
S
G
G
T
E
A
Q
D
W
A
S
M
L
-
E
R
M
-
Y
L
R
W
A
E
S
R
G
F
K
T
E
I
I
E
E
S
E
G
E
V
A
G
I
K
S
V
T
I
K
I
S
G
D
Y
A
Y
G
W
L
R
T
E
T
G
V
H
R
L
V
R
K
S
P
F
D
S
G
G
R
R
H
T
S
F
S
S
A
F
V
Y
P
E
V
D
D
D
I
D
I
-
E
I
N
P
A
D
L
R
I
D
V
Y
R
T
S
G
A
G
G
Q
H
V
N
R
T
E
S
A
V
R
I
T
---------------------
H
------
I
P
------------------
T
---
G
---
I
V
T
Q
C
Q
N
D
R
S
Q
H
K
N
K
D
Q
A
-
M
K
Q
M
-
K
A
K
L
Y
E
L
E
-
M
Q
K
K
N
A
E
K
Q
-
A
ME
D
N
K
S
D
I
G
W
G
---
S
Q
I
R
S
Y
V
L
D
D
S
R
I
K
D
L
R
T
G
V
E
T
R
N
T
Q
A
V
L
D
G
S
L
D
Q
F
I
E
A
----------------
21
HHSearch
68.17
49%
-45
- C8 -
-
1RQ0
-
C:
[801-1133]
--------------------------
M
K
E
K
K
K
E
I
E
K
L
L
A
R
P
D
L
T
P
E
--
Q
M
K
N
Y
G
M
E
Y
A
K
I
E
E
I
E
N
I
T
N
R
-
I
K
E
T
Q
E
F
I
----
E
L
L
R
E
E
G
E
N
------
E
L
E
I
E
K
Y
E
K
E
L
D
Q
L
Y
Q
E
L
L
F
L
L
---------
S
P
E
---
A
S
D
K
A
I
V
E
I
R
P
G
T
G
G
E
E
A
A
L
F
A
R
D
L
-
F
R
M
-
Y
T
R
Y
A
E
R
K
G
W
N
L
E
V
A
E
I
H
E
T
D
L
G
G
I
R
E
V
V
F
F
V
K
G
K
N
A
Y
G
I
L
K
Y
E
S
G
V
H
R
V
Q
R
V
P
V
T
E
S
G
G
R
I
H
T
S
T
A
T
V
A
V
L
P
E
I
E
E
-
K
D
I
-
E
I
R
P
E
D
L
K
I
E
T
F
R
A
S
G
---------
E
S
A
V
R
I
T
---------------------
H
------
L
P
------------------
T
---
G
---
I
V
V
S
C
Q
N
E
R
S
Q
Y
Q
N
K
Q
T
A
-
L
R
I
L
-
R
A
R
L
Y
Q
L
Q
-
K
E
Q
K
E
R
E
I
S
-
Q
------------
R
S
E
K
I
R
T
Y
N
F
P
Q
N
R
V
T
D
H
R
I
N
Y
T
S
Y
R
L
Q
E
I
L
D
G
D
L
D
E
I
I
S
K
L
I
E
H
D
I
E
N
N
L
E
E
V
L
--
22
HHSearch
67.39
49%
-
- C8 -
-
2FVO
-
RF1_THEMA
A:
[1-331]
--------------------------
M
K
E
K
K
K
E
I
E
K
L
L
A
R
P
D
L
T
P
E
--
Q
M
K
N
Y
G
M
E
Y
A
K
I
E
E
I
E
N
I
T
N
R
-
I
K
E
T
Q
E
F
I
E
----
L
L
R
E
E
G
E
N
------
E
L
E
I
E
K
Y
E
K
E
L
D
Q
L
Y
Q
E
L
L
F
L
L
---------
S
P
E
---
A
S
D
K
A
I
V
E
I
R
P
G
T
G
G
E
E
A
A
L
F
A
R
D
L
-
F
R
M
-
Y
T
R
Y
A
E
R
K
G
W
N
L
E
V
A
E
I
H
E
T
D
L
G
G
I
R
E
V
V
F
F
V
K
G
K
N
A
Y
G
I
L
K
Y
E
S
G
V
H
R
V
Q
R
V
P
V
T
E
S
G
G
R
I
H
T
S
T
A
T
V
A
V
L
P
E
I
E
E
-
K
D
I
-
E
I
R
P
E
D
L
K
I
E
T
F
R
A
S
G
---------
E
S
A
V
R
I
T
---------------------
H
------
L
P
------------------
T
---
G
---
I
V
V
S
C
Q
N
E
R
S
Q
Y
Q
N
K
Q
T
A
-
L
R
I
L
-
R
A
R
L
Y
Q
L
Q
-
K
E
Q
K
E
R
E
I
S
-
Q
------------
R
S
E
K
I
R
T
Y
N
F
P
Q
N
R
V
T
D
H
R
I
N
Y
T
S
Y
R
L
Q
E
I
L
D
G
D
L
D
E
I
I
S
K
L
I
E
H
D
I
E
N
N
L
E
E
----
18
HHSearch
64.91
35%
4
- C8 -
-
1GQE
-
RF2_ECOLI
A:
[26-363]
----------------------
D
Y
D
A
K
K
E
R
L
E
E
V
N
A
E
L
E
Q
P
D
V
W
N
E
P
E
R
A
Q
A
L
G
K
E
R
S
S
L
E
A
V
V
D
T
L
D
Q
-
M
K
Q
G
L
E
D
V
S
G
L
L
E
L
A
V
E
A
D
D
E
E
T
F
N
E
A
V
A
E
L
D
A
L
E
E
K
L
A
Q
L
E
F
R
R
---
M
----
F
S
---
G
E
Y
---
D
S
A
D
C
Y
L
D
I
Q
A
G
S
G
G
T
E
A
Q
D
W
A
S
M
L
-
E
R
M
-
Y
L
R
W
A
E
S
R
G
F
K
T
E
I
I
E
E
S
E
G
E
V
A
G
I
K
S
V
T
I
K
I
S
G
D
Y
A
Y
G
W
L
R
T
E
T
G
V
H
R
L
V
R
K
S
P
F
D
S
G
G
R
R
H
T
S
F
S
S
A
F
V
Y
P
E
V
D
D
D
I
D
I
-
E
I
N
P
A
D
L
R
I
D
V
Y
R
A
S
G
A
G
G
Q
H
V
N
R
T
E
S
A
V
R
I
T
---------------------
H
------
I
P
------------------
T
---
G
---
I
V
T
Q
C
Q
N
D
R
S
Q
H
K
N
K
D
Q
A
-
M
K
Q
M
-
K
A
K
L
Y
E
V
E
-
M
Q
K
K
N
A
E
K
Q
-
A
---
M
E
D
N
K
S
D
I
G
W
G
S
Q
I
R
S
Y
V
L
D
D
S
R
I
K
D
L
R
T
G
V
E
T
R
N
T
Q
A
V
L
D
G
S
L
D
Q
F
I
E
A
S
L
K
A
------------
1
PsiBlast_PDB
64.25
50%
-16
- C8 -
-
2B3T
-
RF1_ECOLI
B:
[8-354]
----------------------
K
L
E
A
L
H
E
R
H
E
E
V
Q
A
L
L
G
D
A
Q
T
I
A
D
Q
E
R
F
R
A
L
S
R
E
Y
A
Q
L
S
D
V
S
R
C
F
T
D
-
W
Q
Q
V
--------------------------------------
Q
Q
L
Q
V
L
L
--
L
-
P
K
---
D
P
D
---
D
E
R
N
A
F
L
E
V
R
A
G
T
G
G
D
E
A
A
L
F
A
G
D
L
-
F
R
M
-
Y
S
R
Y
A
E
A
R
R
W
R
V
E
I
M
S
A
S
E
G
E
H
G
G
Y
K
E
I
I
A
K
I
S
G
D
G
V
Y
G
R
L
K
F
E
S
G
G
H
R
V
Q
R
V
P
A
T
E
S
Q
G
R
I
H
T
S
A
C
T
V
A
V
M
P
E
L
P
D
-
A
E
L
P
D
V
N
P
A
D
L
R
I
D
T
F
R
S
S
G
A
G
G
Q
H
V
N
T
T
D
S
A
I
R
I
T
---------------------
H
------
L
P
------------------
T
---
G
---
I
V
V
E
C
Q
D
E
R
S
Q
H
K
N
K
A
K
A
-
L
S
V
L
-
G
A
R
I
H
A
A
E
-
M
A
K
R
Q
---------
R
R
N
-------
S
D
R
N
R
T
Y
N
F
P
Q
G
R
V
T
D
H
R
I
N
L
T
L
Y
R
L
D
E
V
M
E
G
K
L
D
M
L
I
E
P
I
I
Q
E
H
Q
A
D
Q
L
A
-----
4
PsiBlast_PDB
63.86
36%
-
- C8 -
-
1MI6
-
RF2_ECOLI
A:
[24-359]
--------------------
Y
L
D
Y
D
A
K
K
E
R
L
E
E
V
N
A
E
L
E
Q
P
D
V
W
N
E
P
E
R
A
Q
A
L
G
K
E
R
S
S
L
E
A
V
V
D
T
L
D
Q
-
M
K
---
Q
G
L
E
D
V
S
G
L
L
E
L
A
V
E
A
D
D
E
E
T
F
N
E
A
V
A
E
L
----
D
A
L
E
E
K
L
A
Q
L
E
--
F
-
R
R
MFS
G
E
Y
---
D
S
A
D
C
Y
L
D
I
Q
A
G
S
G
G
T
E
A
Q
D
W
A
S
M
L
-
E
R
M
-
Y
L
R
W
A
E
S
R
G
F
K
T
E
I
I
E
E
S
E
G
E
V
A
G
I
K
S
V
T
I
K
I
S
G
D
Y
A
Y
G
W
L
R
T
E
T
G
V
H
R
L
V
R
K
S
P
F
D
S
G
G
R
R
H
T
S
F
S
S
A
F
V
Y
P
E
V
D
D
D
I
D
I
-
E
I
N
P
A
D
L
R
I
D
V
Y
R
A
S
G
A
G
G
Q
H
V
N
R
T
E
S
A
V
R
I
T
---------------------
H
------
I
P
------------------
T
---
G
---
I
V
T
Q
C
Q
N
D
R
S
Q
H
K
N
K
D
Q
A
-
M
K
Q
M
-
K
A
K
L
Y
E
V
E
-
M
Q
K
K
N
A
E
K
Q
-
A
M
E
D
N
K
S
D
I
G
W
G
---
S
Q
I
R
S
Y
V
L
D
D
S
R
I
K
D
L
R
T
G
V
E
T
R
N
T
Q
A
V
L
D
G
S
L
D
Q
F
I
E
A
----------------
2
PsiBlast_PDB
61.32
56%
-46
- C8 -
-
1RQ0
-
RF1_THEMA
A:
[64-330]
--------------------------------------------------------------------------------------------------------
K
Y
E
K
E
-
L
D
Q
L
Y
Q
E
L
L
--
F
-
L
L
---
S
P
E
---
A
S
D
K
A
I
V
E
I
R
P
G
T
G
G
E
E
A
A
L
F
A
R
D
L
-
F
R
M
-
Y
T
R
Y
A
E
R
K
G
W
N
L
E
V
A
E
I
H
E
T
D
L
G
G
I
R
E
V
V
F
F
V
K
G
K
N
A
Y
G
I
L
K
Y
E
S
G
V
H
R
V
Q
R
V
P
V
T
E
S
G
G
R
I
H
T
S
T
A
T
V
A
V
L
P
E
I
E
E
-
K
D
I
-
E
I
R
P
E
D
L
K
I
E
T
F
R
A
S
G
----
Y
V
N
K
T
E
S
A
V
R
I
T
---------------------
H
------
L
P
------------------
T
---
G
---
I
V
V
S
C
Q
N
E
R
S
Q
Y
Q
N
K
Q
T
A
-
L
R
I
L
-
R
A
R
L
Y
Q
L
Q
-
K
E
Q
K
E
R
E
I
S
-
Q
------------
R
S
E
K
I
R
T
Y
N
F
P
Q
N
R
V
T
D
H
R
I
N
Y
T
S
Y
R
L
Q
E
I
L
D
G
D
L
D
E
I
I
S
K
L
I
E
H
D
I
E
N
N
L
E
-----
6
PsiBlast_PDB
59.51
35%
43
- C8 -
-
1GQE
-
RF2_ECOLI
A:
[24-361]
--------------------
Y
L
D
Y
D
A
K
K
E
R
L
E
E
V
N
A
E
L
E
Q
P
D
V
W
N
E
P
E
R
A
Q
A
L
G
K
E
R
S
S
L
E
A
V
V
D
T
L
D
Q
-
M
K
---
Q
G
L
E
D
V
S
G
L
L
E
L
A
V
E
A
D
D
E
E
T
F
N
E
A
V
A
E
L
----
D
A
L
E
E
K
L
A
Q
L
E
--
F
-
R
R
---
M
F
S
GEY
D
S
A
D
C
Y
L
D
I
Q
A
G
S
G
G
T
E
A
Q
D
W
A
S
M
L
-
E
R
M
-
Y
L
R
W
A
E
S
R
G
F
K
T
E
I
I
E
E
S
E
G
E
V
A
G
I
K
S
V
T
I
K
I
S
G
D
Y
A
Y
G
W
L
R
T
E
T
G
V
H
R
L
V
R
K
S
P
F
D
S
G
G
R
R
H
T
S
F
S
S
A
F
V
Y
P
E
V
D
D
D
I
D
I
-
E
I
N
P
A
D
L
R
I
D
V
Y
R
A
S
G
A
G
G
Q
H
V
N
R
T
E
S
A
V
R
I
T
---------------------
H
------
I
P
------------------
T
---
G
---
I
V
T
Q
C
Q
N
D
R
S
Q
H
K
N
K
D
Q
A
-
M
K
Q
M
-
K
A
K
L
Y
E
V
E
-
M
Q
K
K
N
A
E
K
Q
-
A
ME
D
N
K
S
D
I
G
W
G
---
S
Q
I
R
S
Y
V
L
D
D
S
R
I
K
D
L
R
T
G
V
E
T
R
N
T
Q
A
V
L
D
G
S
L
D
Q
F
I
E
A
S
L
--------------
3
PsiBlast_PDB
58.52
56%
-
- C8 -
-
2FVO
-
RF1_THEMA
A:
[64-330]
--------------------------------------------------------------------------------------------------------
K
Y
E
K
E
-
L
D
Q
L
Y
Q
E
L
L
--
F
-
L
L
---
S
P
E
---
A
S
D
K
A
I
V
E
I
R
P
G
T
G
G
E
E
A
A
L
F
A
R
D
L
-
F
R
M
-
Y
T
R
Y
A
E
R
K
G
W
N
L
E
V
A
E
I
H
E
T
D
L
G
G
I
R
E
V
V
F
F
V
K
G
K
N
A
Y
G
I
L
K
Y
E
S
G
V
H
R
V
Q
R
V
P
V
T
E
S
G
G
R
I
H
T
S
T
A
T
V
A
V
L
P
E
I
E
E
-
K
D
I
-
E
I
R
P
E
D
L
K
I
E
T
F
R
A
S
G
---------
E
S
A
V
R
I
T
---------------------
H
------
L
P
------------------
T
---
G
---
I
V
V
S
C
Q
N
E
R
S
Q
Y
Q
N
K
Q
T
A
-
L
R
I
L
-
R
A
R
L
Y
Q
L
Q
-
K
E
Q
K
E
R
E
I
S
-
Q
------------
R
S
E
K
I
R
T
Y
N
F
P
Q
N
R
V
T
D
H
R
I
N
Y
T
S
Y
R
L
Q
E
I
L
D
G
D
L
D
E
I
I
S
K
L
I
E
H
D
I
E
N
N
L
E
-----
35
Fugue
53.99
33%
89
- C8 -
-
1GQE
-
RF2_ECOLI
A:
[4-365]
IN
P
V
N
N
R
I
Q
D
L
T
E
R
S
D
V
L
R
G
Y
L
D
Y
D
A
K
K
E
R
L
E
E
V
N
A
E
L
E
Q
P
D
V
W
N
E
P
E
R
A
Q
A
L
G
K
E
R
S
S
L
E
A
V
V
D
T
L
D
Q
M
K
Q
G
L
E
D
V
S
G
L
L
E
L
A
V
E
A
D
-
D
E
E
T
F
N
E
A
V
A
E
L
D
A
L
E
E
K
L
A
Q
L
E
F
R
-------
R
M
F
S
---
G
E
Y
---
D
S
A
D
C
Y
L
D
I
Q
A
G
S
G
G
T
E
A
Q
D
W
A
S
--
M
L
E
R
M
Y
L
R
W
A
E
S
R
G
F
K
T
E
I
I
E
E
S
E
G
E
V
A
G
I
K
S
V
T
I
K
I
S
G
D
Y
A
Y
G
W
L
R
T
E
T
G
V
H
R
L
V
R
K
S
P
F
D
S
G
G
R
R
H
T
S
F
S
S
A
F
V
Y
P
E
V
D
D
D
I
D
I
-
E
I
N
P
A
D
L
R
I
D
V
Y
R
A
S
G
A
G
G
Q
H
V
N
R
T
E
S
A
V
R
I
T
---------------------
H
------
I
P
------------------
T
---
G
---
I
V
T
Q
C
Q
N
D
R
S
Q
H
K
N
K
D
Q
A
M
K
Q
--
M
K
A
K
L
Y
E
V
E
M
Q
K
K
N
A
E
K
Q
A
M
E
--
D
N
K
S
D
I
G
W
G
S
---
Q
I
R
S
Y
V
L
D
D
S
R
I
K
D
L
R
T
G
V
E
T
R
N
T
Q
A
V
L
D
G
S
L
D
Q
F
I
E
A
S
L
K
A
G
L
----------
34
HHSearch
45.08
24%
-140
- C8 -
-
5J10
-
?
B:
[20-69]
----------------------------------------------------------------
E
L
L
K
E
-
I
K
K
L
V
E
E
I
A
R
L
V
K
E
I
Q
E
D
P
S
D
E
L
L
K
T
L
A
E
L
V
R
K
L
K
E
L
V
E
D
M
E
R
S
M
--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
24
HHSearch
36.40
27%
-53
- C8 -
-
2RSM
-
CL065_MOUSE
A:
[4-111]
------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
G
S
S
G
K
W
G
L
R
L
Q
E
K
P
A
L
L
F
P
-
G
M
A
A
S
T
V
Q
V
A
G
R
K
D
Y
P
A
--
L
L
-
P
L
N
E
S
E
L
E
E
Q
F
V
K
G
H
G
P
G
G
Q
A
T
N
K
T
S
N
C
V
V
L
K
---------------------
H
------
V
P
------------------
S
---
G
---
I
V
V
K
C
H
Q
T
R
S
V
D
Q
N
R
K
I
A
-
R
K
V
L
-
Q
E
K
V
D
V
F
Y
-
N
S
G
-----------------------------------------------------------------------------
28
HHSearch
36.02
41%
-66
- C8 -
-
2JY9
-
?
A:
[8-102]
----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
V
-
S
I
A
D
N
E
L
E
I
T
A
I
R
A
Q
G
A
G
G
Q
H
V
N
K
T
S
S
A
I
H
L
R
F
D
IRA
S
G
L
P
E
Y
Y
K
Q
R
L
L
T
ASH
H
------
L
I
------------------
S
DDG
V
---
I
I
I
K
A
Q
E
F
R
S
Q
E
L
N
R
E
A
A
-
I
A
R
L
-
V
A
V
I
K
E
L
T
-
A
E
Q
-----------------------------------------------------------------------------
26
HHSearch
34.80
37%
-56
- C8 -
-
2JVA
-
?
A:
[7-101]
---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
N
V
-
H
L
P
D
A
E
I
E
L
T
A
I
R
A
Q
G
A
G
G
Q
N
V
N
K
V
S
S
A
M
H
L
R
---------------------
F
DINASS
L
P
P
F
Y
K
E
R
L
L
A
LNDSRITS-
D
---
G
V
--
I
V
L
K
A
Q
Q
Y
R
T
Q
E
Q
N
R
A
D
A
-
L
L
R
L
-
S
E
L
I
V
N
A
A
-
K
L
------------------------------------------------------------------------------
7
PsiBlast_PDB
34.73
35%
-76
- C8 -
-
2RSM
-
CL065_MOUSE
A:
[41-104]
----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
L
-
P
L
N
E
S
E
L
E
E
Q
F
V
K
G
H
G
P
G
G
Q
A
T
N
K
T
S
N
C
V
V
L
K
---------------------
H
------
V
P
------------------
S
---
G
---
I
V
V
K
C
H
Q
T
R
S
V
D
Q
N
R
K
I
A
-
R
K
V
L
-
Q
E
K
V
-------------------------------------------------------------------------------------
27
HHSearch
33.29
40%
-50
- C8 -
-
2RTX
-
ARFB_ECOLI
A:
[8-104]
----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
V
-
A
I
P
D
G
E
L
E
I
T
A
I
R
A
Q
G
A
G
G
Q
H
V
N
K
T
S
T
A
I
H
L
R
F
DIRAS---------------
S
------
L
P
E
Y
Y
K
E
R
L
L
A
ASHHLISSD
G
---
V
---
I
V
I
K
A
Q
E
Y
R
S
Q
E
L
N
R
E
A
A
-
L
A
R
L
-
V
A
M
I
K
E
L
T
-
T
E
K
K
A
---------------------------------------------------------------------------
41
Fugue
32.27
13%
-35
- C8 -
-
1SET
-
SYS_THET2
A:
[1-110]
--------------------
M
V
D
L
K
R
L
R
Q
E
P
E
V
F
H
R
A
I
R
E
K
G
V
A
L
D
L
E
A
L
L
A
L
D
R
E
V
Q
E
L
K
K
R
L
Q
E
V
Q
T
-
E
R
N
Q
V
A
K
R
V
P
K
A
P
P
E
E
K
E
A
L
I
A
R
G
K
A
L
G
E
E
A
K
R
L
E
E
A
L
R
E
K
E
A
R
L
E
A
L
L
L
Q
V
-
P
L
---
P
P
W
---
P
G
A
P
---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
10
PsiBlast_PDB
31.10
43%
-83
- C7 -
-
2JVA
-
?
A:
[8-39]
----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
V
-
H
L
P
D
A
E
I
E
L
T
A
I
R
A
Q
G
A
G
G
Q
N
V
N
K
V
S
S
A
M
H
L
--------------------------------------------------------------------------------------------------------------------------------------------------------------------------
9
PsiBlast_PDB
30.35
33%
-66
- C8 -
-
2JY9
-
?
A:
[8-88]
----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
V
-
S
I
A
D
N
E
L
E
I
T
A
I
R
A
Q
G
A
G
G
Q
H
V
N
K
T
S
S
A
I
H
L
R
F
D
IRA
S
G
L
P
E
Y
Y
K
Q
R
L
L
T
ASH
H
------
L
I
------------------
S
---
D
DG
V
I
I
I
K
A
Q
E
F
R
S
Q
E
L
N
R
E
A
A
-
I
---------------------------------------------------------------------------------------------