@TOME V2.3
(Mar 2018)
Ref.
-
-
Doc.
Global output mode :
Sort entries by :
Atome Result
Tools Result
PDB occurence
Core Structure Cluster
Sequence Color type :
Secondary Structure
Hydrophobicity
Disulfide Bonds
TCoffee Identity Score
Uniprot annotation
Core Structure Cluster
Contacts with Ligands
Show alignment :
Atome selection
All alignments
Only Template with Ligand
Column output:
Score:
Atome Rank Value
Tools Score
Hide column
Alignment:
Sequence Identity (%)
Tcoffee Alignment Score
Hide column
3D Common Core:
Tito PKB Score
Verify3D Score
QMean Score
Hide column
Structural Clustering:
Cluster Num
3D-Jury Struct. Score
Hide column
Modeller Result :
Model Rank
QMean Score
Dfire Score
Dope Score
Errat Score
Verify3D Score
Modeller Score
Hide column
Complexes Modeling
Show Ligands of Templates
Complexes Affinity Score
Main Binding Site Identity
Hide column
Templates Information:
Uniprot entry
Cath class
Scop class
Smart class
Prosite class
Pfam class
EC Number
Taxonomy
Experiment Method
Hide column
Sequence & Result Tab:
PDB Template Sequence
Complexes Tab
Values color: [
Good
|
Correct
|
Middling
|
Bad
]
Sequence color :
Mutated
Helix
Strand
Conserved
Query sequence : Q3XZ59: (2018-01-12 )
MDYSSKEYFDKMTAWWRAANYLSVGQLYLKDNPLLRRTLKPEDVKKHPIGHWGTIPGQNFIYVHLNRVINKYDLNMFYIEGPGHGGQVMVSNAYLDGSYTEIYPEVTEDETGMQKLFKRFSFPGGIASHAAPETPGSIHEGGELGYSLSHAVGAVLDNPEVISAVVIGDGEAETGPLAGSWFSNVFINPVIDGAVLPILHLNGAKIANPTILARKSDGELANYFNGLGWEPFFIEGNDSEKLNPVMAEKMDQAIEKIKSIQKEARLKTATDVVMPKWPVLIVRTPKGWTGPKEWDGEPIEGTFRAHQVPIPVDQEHMDHADALLRWLKSYEPEKLFDAQGRILEEIREIAPTGDQRMAKNPITNGGIDPRPLIMPDWKKYTLQFEKPGSVKAEDMTELGKFVREIIEKNPENFRIFGPDETKSNRLNQVFKTTNRQWMEKIEPENDEWLSPSGRVIDSQLSEHQDEGFLEGYVLTGRHGFLQVTNHSCEWLTLC
Atome Classification :
(20 SA)
---------.........10........20........30........40........50........60-........70------.........80........90........100.......110.......120.......130-.......140.......150......-----------------.160.......170.......180.......190.......200.......210.......220.......230-.-.----....---.---240-.........250.......260.......270.....--..280.......290.......300.......310.......320.......330.......340.......350.---.....----.360.........370---...-....380.---.---...---..390.......400.......410.......420.......430.....-..-440..-.-....450.......460.......470.....-..480.......490..-------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
(Atome)
(Ident)
(Tito)
(Num)
(QMean)
(Ligand)
(Uniprot)
---------MDY
S
S
K
E
Y
F
D
K
M
T
A
W
W
R
A
A
N
Y
L
S
V
G
Q
L
Y
LKDN
P
L
L
RRTL
K
P
E
D
VKKHPIGHWGTIPGQ
N
F
I
-
Y
V
H
L
N
R
V
I
N
-------KYD
L
N
M
F
Y
I
EGPGHG
G
Q
V
M
V
S
N
A
Y
LDG
S
Y
T
EIYPEVTE
D
E
T
G
M
Q
K
L
F
K
RFSFPGGIASHAAP-ETPGSIHEGGEL
G
Y
S
L
S
H
A
V
G
A
VLDN-----------------P
E
V
I
S
A
V
V
I
GDGEAETGPL
A
G
S
W
F
S
N
V
F
INPVIDG
A
V
L
P
I
L
HLNGAKIAN
P
T
I
L
A
RKSDG
E
L
A
N
Y
F
NGLGW
E
P
F
-
F
-
I
----EGND---S---E---KL
N
P
V
M
A
E
K
M
D
Q
A
I
E
K
I
K
S
I
Q
K
E
ARLKTATDVVMPKW--
P
V
L
I
V
RTPKGWTGPKEWDGEPIE
G
T
FRAHQVPIPV
D
Q
E
H
M
D
H
A
D
A
L
L
R
W
L
K
SYE
P
E
K
L
F
D
A
Q
G
R
I
L
E
E
I
R
E
IAPTG---DQRMA----KN--PITNGGIDPRPL---IMP-DWK
K
Y
T
L
Q
---F---EKP---GSV
K
A
E
D
M
T
E
L
G
K
F
V
R
E
I
I
EKNPE
N
F
R
I
FGPDETK
S
N
R
L
N
Q
V
F
K
TT
N
R
Q
W
-
M
E
-KIEPE-N-DEWLSPSGR
V
I
D
S
Q
L
S
E
H
Q
D
EGFLE
G
Y
V
LTGR-H
G
F
L
Q
VTNHS
C
E
W
L
TLC-------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
5
PsiBlast_PDB
85.96
49%
-9
- C9 -
-
3AHJ
7
?
A:
[38-516]
-------------
S
E
E
A
I
E
G
M
D
K
Y
W
R
V
T
N
Y
M
S
I
G
Q
I
Y
L
R
S
N
P
L
M
K
E
P
F
T
R
D
D
V
K
H
R
L
V
G
H
W
G
T
T
P
G
L
N
F
L
-
L
A
H
I
N
R
L
I
A
-------
D
H
Q
Q
N
T
V
F
I
M
G
P
G
H
G
G
P
A
G
T
S
Q
S
Y
V
D
G
T
Y
T
E
Y
Y
P
N
I
T
K
D
E
A
G
L
Q
K
F
F
R
Q
F
S
Y
P
G
G
I
P
S
H
F
A
P
-
E
T
P
G
S
I
H
E
G
G
E
L
G
Y
A
L
S
H
A
Y
G
A
V
M
N
N
-----------------
P
S
L
F
V
P
C
I
I
G
D
G
E
A
E
T
G
P
L
A
T
G
W
Q
S
N
K
L
V
N
P
R
T
D
G
I
V
L
P
I
L
H
L
N
G
Y
K
I
A
N
P
T
I
L
A
R
I
S
D
E
E
L
H
D
F
F
R
G
M
G
Y
H
P
Y
E
F
-
V
----
A
G
F
D
---
N
---
E
D
H
M
S
I
H
R
R
F
A
E
L
F
E
T
I
F
D
E
I
C
D
I
K
A
A
A
Q
---
T
D
D
M
T
R
P
F
Y
--
P
M
L
I
F
R
T
P
K
G
W
T
C
P
K
F
I
D
G
K
K
T
E
G
S
W
R
A
H
Q
V
P
L
A
S
A
R
D
T
E
E
H
F
E
V
L
K
G
W
M
E
S
Y
K
P
E
E
L
F
N
A
D
G
S
I
K
D
D
V
T
A
F
M
P
K
G
---
E
L
R
I
G
----
A
N
--
P
N
A
N
G
G
V
I
R
E
D
L
---
K
L
P
-
E
L
D
Q
Y
E
V
T
---
G
---
V
K
E
YGH
G
W
G
Q
V
E
A
P
R
A
L
G
A
Y
C
R
D
I
I
K
N
N
P
D
S
F
R
I
F
G
P
D
E
T
A
S
N
R
L
N
A
T
Y
E
V
T
D
K
Q
W
-
D
N
G
Y
L
S
G
L
-
V
-
D
E
H
M
A
V
T
G
Q
V
T
E
-
Q
L
S
E
H
Q
C
E
G
F
L
E
A
Y
L
L
T
G
R
-
H
G
----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
8
PsiBlast_PDB
85.91
49%
-10
- C9 -
-
3AHH
7
?
A:
[38-516]
-------------
S
E
E
A
I
E
G
M
D
K
Y
W
R
V
T
N
Y
M
S
I
G
Q
I
Y
L
R
S
N
P
L
M
K
E
P
F
T
R
D
D
V
K
H
R
L
V
G
H
W
G
T
T
P
G
L
N
F
L
-
L
A
H
I
N
R
L
I
A
-------
D
H
Q
Q
N
T
V
F
I
M
G
P
G
H
G
G
P
A
G
T
S
Q
S
Y
V
D
G
T
Y
T
E
Y
Y
P
N
I
T
K
D
E
A
G
L
Q
K
F
F
R
Q
F
S
Y
P
G
G
I
P
S
A
F
A
P
-
E
T
P
G
S
I
H
E
G
G
E
L
G
Y
A
L
S
H
A
Y
G
A
V
M
N
N
-----------------
P
S
L
F
V
P
C
I
I
G
D
G
E
A
E
T
G
P
L
A
T
G
W
Q
S
N
K
L
V
N
P
R
T
D
G
I
V
L
P
I
L
H
L
N
G
Y
K
I
A
N
P
T
I
L
A
R
I
S
D
E
E
L
H
D
F
F
R
G
M
G
Y
H
P
Y
E
F
-
V
----
A
G
F
D
---
N
---
E
D
H
M
S
I
H
R
R
F
A
E
L
F
E
T
I
F
D
E
I
C
D
I
K
A
A
A
Q
---
T
D
D
M
T
R
P
F
Y
--
P
M
L
I
F
R
T
P
K
G
W
T
C
P
K
F
I
D
G
K
K
T
E
G
S
W
R
A
H
Q
V
P
L
A
S
A
R
D
T
E
E
H
F
E
V
L
K
G
W
M
E
S
Y
K
P
E
E
L
F
N
A
D
G
S
I
K
D
D
V
T
A
F
M
P
K
G
---
E
L
R
I
G
----
A
N
--
P
N
A
N
G
G
V
I
R
E
D
L
---
K
L
P
-
E
L
D
Q
Y
E
V
T
---
G
---
V
K
E
YGH
G
W
G
Q
V
E
A
P
R
A
L
G
A
Y
C
R
D
I
I
K
N
N
P
D
S
F
R
I
F
G
P
D
E
T
A
S
N
R
L
N
A
T
Y
E
V
T
D
K
Q
W
-
D
N
G
Y
L
S
G
L
-
V
-
D
E
H
M
A
V
T
G
Q
V
T
E
-
Q
L
S
E
H
Q
C
E
G
F
L
E
A
Y
L
L
T
G
R
-
H
G
----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
4
PsiBlast_PDB
85.85
49%
-9
- C9 -
-
3AHF
3
?
A:
[38-516]
-------------
S
E
E
A
I
E
G
M
D
K
Y
W
R
V
T
N
Y
M
S
I
G
Q
I
Y
L
R
S
N
P
L
M
K
E
P
F
T
R
D
D
V
K
H
R
L
V
G
H
W
G
T
T
P
G
L
N
F
L
-
L
A
H
I
N
R
L
I
A
-------
D
H
Q
Q
N
T
V
F
I
M
G
P
G
H
G
G
P
A
G
T
S
Q
S
Y
V
D
G
T
Y
T
E
Y
Y
P
N
I
T
K
D
E
A
G
L
Q
K
F
F
R
Q
F
S
Y
P
G
G
I
P
S
H
F
A
P
-
E
T
P
G
S
I
H
E
G
G
E
L
G
Y
A
L
S
H
A
Y
G
A
V
M
N
N
-----------------
P
S
L
F
V
P
C
I
I
G
D
G
E
A
E
T
G
P
L
A
T
G
W
Q
S
N
K
L
V
N
P
R
T
D
G
I
V
L
P
I
L
H
L
N
G
Y
K
I
A
N
P
T
I
L
A
R
I
S
D
E
E
L
H
D
F
F
R
G
M
G
Y
H
P
Y
E
F
-
V
----
A
G
F
D
---
N
---
E
D
H
M
S
I
H
R
R
F
A
E
L
F
E
T
I
F
D
E
I
C
D
I
K
A
A
A
Q
---
T
D
D
M
T
R
P
F
Y
--
P
M
L
I
F
R
T
P
K
G
W
T
C
P
K
F
I
D
G
K
K
T
E
G
S
W
R
A
H
Q
V
P
L
A
S
A
R
D
T
E
E
H
F
E
V
L
K
G
W
M
E
S
Y
K
P
E
E
L
F
N
A
D
G
S
I
K
D
D
V
T
A
F
M
P
K
G
---
E
L
R
I
G
----
A
N
--
P
N
A
N
G
G
V
I
R
E
D
L
---
K
L
P
-
E
L
D
Q
Y
E
V
T
---
G
---
V
K
E
YGH
G
W
G
Q
V
E
A
P
R
A
L
G
A
Y
C
R
D
I
I
K
N
N
P
D
S
F
R
I
F
G
P
D
E
T
A
S
N
R
L
N
A
T
Y
E
V
T
D
K
Q
W
-
D
N
G
Y
L
S
G
L
-
V
-
D
E
H
M
A
V
T
G
Q
V
T
E
-
Q
L
S
E
H
Q
C
E
G
F
L
E
A
Y
L
L
T
G
R
-
H
G
----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
9
PsiBlast_PDB
85.77
49%
-9
- C9 -
-
3AHI
6
?
A:
[38-516]
-------------
S
E
E
A
I
E
G
M
D
K
Y
W
R
V
T
N
Y
M
S
I
G
Q
I
Y
L
R
S
N
P
L
M
K
E
P
F
T
R
D
D
V
K
H
R
L
V
G
H
W
G
T
T
P
G
L
N
F
L
-
L
A
H
I
N
R
L
I
A
-------
D
H
Q
Q
N
T
V
F
I
M
G
P
G
H
G
G
P
A
G
T
S
Q
S
Y
V
D
G
T
Y
T
E
Y
Y
P
N
I
T
K
D
E
A
G
L
Q
K
F
F
R
Q
F
S
Y
P
G
G
I
P
S
H
F
A
P
-
E
T
P
G
S
I
H
E
G
G
E
L
G
Y
A
L
S
H
A
Y
G
A
V
M
N
N
-----------------
P
S
L
F
V
P
C
I
I
G
D
G
E
A
E
T
G
P
L
A
T
G
W
Q
S
N
K
L
V
N
P
R
T
D
G
I
V
L
P
I
L
H
L
N
G
Y
K
I
A
N
P
T
I
L
A
R
I
S
D
E
E
L
H
D
F
F
R
G
M
G
Y
H
P
Y
E
F
-
V
----
A
G
F
D
---
N
---
E
D
H
M
S
I
H
R
R
F
A
E
L
F
E
T
I
F
D
E
I
C
D
I
K
A
A
A
Q
---
T
D
D
M
T
R
P
F
Y
--
P
M
L
I
F
R
T
P
K
G
W
T
C
P
K
F
I
D
G
K
K
T
E
G
S
W
R
A
A
Q
V
P
L
A
S
A
R
D
T
E
E
H
F
E
V
L
K
G
W
M
E
S
Y
K
P
E
E
L
F
N
A
D
G
S
I
K
D
D
V
T
A
F
M
P
K
G
---
E
L
R
I
G
----
A
N
--
P
N
A
N
G
G
V
I
R
E
D
L
---
K
L
P
-
E
L
D
Q
Y
E
V
T
---
G
---
V
K
E
YGH
G
W
G
Q
V
E
A
P
R
A
L
G
A
Y
C
R
D
I
I
K
N
N
P
D
S
F
R
I
F
G
P
D
E
T
A
S
N
R
L
N
A
T
Y
E
V
T
D
K
Q
W
-
D
N
G
Y
L
S
G
L
-
V
-
D
E
H
M
A
V
T
G
Q
V
T
E
-
Q
L
S
E
H
Q
C
E
G
F
L
E
A
Y
L
L
T
G
R
-
H
G
----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
7
PsiBlast_PDB
85.40
49%
-8
- C9 -
-
3AHG
7
?
A:
[38-516]
-------------
S
E
E
A
I
E
G
M
D
K
Y
W
R
V
T
N
Y
M
S
I
G
Q
I
Y
L
R
S
N
P
L
M
K
E
P
F
T
R
D
D
V
K
H
R
L
V
G
A
W
G
T
T
P
G
L
N
F
L
-
L
A
H
I
N
R
L
I
A
-------
D
H
Q
Q
N
T
V
F
I
M
G
P
G
H
G
G
P
A
G
T
S
Q
S
Y
V
D
G
T
Y
T
E
Y
Y
P
N
I
T
K
D
E
A
G
L
Q
K
F
F
R
Q
F
S
Y
P
G
G
I
P
S
H
F
A
P
-
E
T
P
G
S
I
H
E
G
G
E
L
G
Y
A
L
S
H
A
Y
G
A
V
M
N
N
-----------------
P
S
L
F
V
P
C
I
I
G
D
G
E
A
E
T
G
P
L
A
T
G
W
Q
S
N
K
L
V
N
P
R
T
D
G
I
V
L
P
I
L
H
L
N
G
Y
K
I
A
N
P
T
I
L
A
R
I
S
D
E
E
L
H
D
F
F
R
G
M
G
Y
H
P
Y
E
F
-
V
----
A
G
F
D
---
N
---
E
D
H
M
S
I
H
R
R
F
A
E
L
F
E
T
I
F
D
E
I
C
D
I
K
A
A
A
Q
---
T
D
D
M
T
R
P
F
Y
--
P
M
L
I
F
R
T
P
K
G
W
T
C
P
K
F
I
D
G
K
K
T
E
G
S
W
R
A
H
Q
V
P
L
A
S
A
R
D
T
E
E
H
F
E
V
L
K
G
W
M
E
S
Y
K
P
E
E
L
F
N
A
D
G
S
I
K
D
D
V
T
A
F
M
P
K
G
---
E
L
R
I
G
----
A
N
--
P
N
A
N
G
G
V
I
R
E
D
L
---
K
L
P
-
E
L
D
Q
Y
E
V
T
---
G
---
V
K
E
YGH
G
W
G
Q
V
E
A
P
R
A
L
G
A
Y
C
R
D
I
I
K
N
N
P
D
S
F
R
I
F
G
P
D
E
T
A
S
N
R
L
N
A
T
Y
E
V
T
D
K
Q
W
-
D
N
G
Y
L
S
G
L
-
V
-
D
E
H
M
A
V
T
G
Q
V
T
E
-
Q
L
S
E
H
Q
C
E
G
F
L
E
A
Y
L
L
T
G
R
-
H
G
----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
2
PsiBlast_PDB
85.37
49%
-10
- C9 -
-
3AHD
3
?
A:
[38-516]
-------------
S
E
E
A
I
E
G
M
D
K
Y
W
R
V
T
N
Y
M
S
I
G
Q
I
Y
L
R
S
N
P
L
M
K
E
P
F
T
R
D
D
V
K
H
R
L
V
G
H
W
G
T
T
P
G
L
N
F
L
-
L
A
H
I
N
R
L
I
A
-------
D
H
Q
Q
N
T
V
F
I
M
G
P
G
H
G
G
P
A
G
T
S
Q
S
Y
V
D
G
T
Y
T
E
Y
Y
P
N
I
T
K
D
E
A
G
L
Q
K
F
F
R
Q
F
S
Y
P
G
G
I
P
S
H
F
A
P
-
E
T
P
G
S
I
H
E
G
G
E
L
G
Y
A
L
S
H
A
Y
G
A
V
M
N
N
-----------------
P
S
L
F
V
P
C
I
I
G
D
G
E
A
E
T
G
P
L
A
T
G
W
Q
S
N
K
L
V
N
P
R
T
D
G
I
V
L
P
I
L
H
L
N
G
Y
K
I
A
N
P
T
I
L
A
R
I
S
D
E
E
L
H
D
F
F
R
G
M
G
Y
H
P
Y
E
F
-
V
----
A
G
F
D
---
N
---
E
D
H
M
S
I
H
R
R
F
A
E
L
F
E
T
I
F
D
E
I
C
D
I
K
A
A
A
Q
---
T
D
D
M
T
R
P
F
Y
--
P
M
L
I
F
R
T
P
K
G
W
T
C
P
K
F
I
D
G
K
K
T
E
G
S
W
R
A
H
Q
V
P
L
A
S
A
R
D
T
E
E
H
F
E
V
L
K
G
W
M
E
S
Y
K
P
E
E
L
F
N
A
D
G
S
I
K
D
D
V
T
A
F
M
P
K
G
---
E
L
R
I
G
----
A
N
--
P
N
A
N
G
G
V
I
R
E
D
L
---
K
L
P
-
E
L
D
Q
Y
E
V
T
---
G
---
V
K
E
YGH
G
W
G
Q
V
E
A
P
R
A
L
G
A
Y
C
R
D
I
I
K
N
N
P
D
S
F
R
I
F
G
P
D
E
T
A
S
N
R
L
N
A
T
Y
E
V
T
D
K
Q
W
-
D
N
G
Y
L
S
G
L
-
V
-
D
E
H
M
A
V
T
G
Q
V
T
E
-
Q
L
S
E
H
Q
C
E
G
F
L
E
A
Y
L
L
T
G
R
-
H
G
----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
1
PsiBlast_PDB
85.28
49%
-7
- C9 -
-
3AHC
8
?
A:
[38-516]
-------------
S
E
E
A
I
E
G
M
D
K
Y
W
R
V
T
N
Y
M
S
I
G
Q
I
Y
L
R
S
N
P
L
M
K
E
P
F
T
R
D
D
V
K
H
R
L
V
G
H
W
G
T
T
P
G
L
N
F
L
-
L
A
H
I
N
R
L
I
A
-------
D
H
Q
Q
N
T
V
F
I
M
G
P
G
H
G
G
P
A
G
T
S
Q
S
Y
V
D
G
T
Y
T
E
Y
Y
P
N
I
T
K
D
E
A
G
L
Q
K
F
F
R
Q
F
S
Y
P
G
G
I
P
S
H
F
A
P
-
E
T
P
G
S
I
H
E
G
G
E
L
G
Y
A
L
S
H
A
Y
G
A
V
M
N
N
-----------------
P
S
L
F
V
P
C
I
I
G
D
G
E
A
E
T
G
P
L
A
T
G
W
Q
S
N
K
L
V
N
P
R
T
D
G
I
V
L
P
I
L
H
L
N
G
Y
K
I
A
N
P
T
I
L
A
R
I
S
D
E
E
L
H
D
F
F
R
G
M
G
Y
H
P
Y
E
F
-
V
----
A
G
F
D
---
N
---
E
D
H
M
S
I
H
R
R
F
A
E
L
F
E
T
I
F
D
E
I
C
D
I
K
A
A
A
Q
---
T
D
D
M
T
R
P
F
Y
--
P
M
L
I
F
R
T
P
K
G
W
T
C
P
K
F
I
D
G
K
K
T
E
G
S
W
R
A
H
Q
V
P
L
A
S
A
R
D
T
E
E
H
F
E
V
L
K
G
W
M
E
S
Y
K
P
E
E
L
F
N
A
D
G
S
I
K
D
D
V
T
A
F
M
P
K
G
---
E
L
R
I
G
----
A
N
--
P
N
A
N
G
G
V
I
R
E
D
L
---
K
L
P
-
E
L
D
Q
Y
E
V
T
---
G
---
V
K
E
YGH
G
W
G
Q
V
E
A
P
R
A
L
G
A
Y
C
R
D
I
I
K
N
N
P
D
S
F
R
I
F
G
P
D
E
T
A
S
N
R
L
N
A
T
Y
E
V
T
D
K
Q
W
-
D
N
G
Y
L
S
G
L
-
V
-
D
E
H
M
A
V
T
G
Q
V
T
E
-
Q
L
S
E
H
Q
C
E
G
F
L
E
A
Y
L
L
T
G
R
-
H
G
----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
3
PsiBlast_PDB
84.94
49%
-8
- C9 -
-
3AHE
8
?
A:
[38-516]
-------------
S
E
E
A
I
E
G
M
D
K
Y
W
R
V
T
N
Y
M
S
I
G
Q
I
Y
L
R
S
N
P
L
M
K
E
P
F
T
R
D
D
V
K
H
R
L
V
G
H
W
G
T
T
P
G
L
N
F
L
-
L
A
H
I
N
R
L
I
A
-------
D
H
Q
Q
N
T
V
F
I
M
G
P
G
H
G
G
P
A
G
T
S
Q
S
Y
V
D
G
T
Y
T
E
Y
Y
P
N
I
T
K
D
E
A
G
L
Q
K
F
F
R
Q
F
S
Y
P
G
G
I
P
S
H
F
A
P
-
E
T
P
G
S
I
H
E
G
G
E
L
G
Y
A
L
S
H
A
Y
G
A
V
M
N
N
-----------------
P
S
L
F
V
P
C
I
I
G
D
G
E
A
E
T
G
P
L
A
T
G
W
Q
S
N
K
L
V
N
P
R
T
D
G
I
V
L
P
I
L
H
L
N
G
Y
K
I
A
N
P
T
I
L
A
R
I
S
D
E
E
L
H
D
F
F
R
G
M
G
Y
H
P
Y
E
F
-
V
----
A
G
F
D
---
N
---
E
D
H
M
S
I
H
R
R
F
A
E
L
F
E
T
I
F
D
E
I
C
D
I
K
A
A
A
Q
---
T
D
D
M
T
R
P
F
Y
--
P
M
L
I
F
R
T
P
K
G
W
T
C
P
K
F
I
D
G
K
K
T
E
G
S
W
R
A
H
Q
V
P
L
A
S
A
R
D
T
E
E
H
F
E
V
L
K
G
W
M
E
S
Y
K
P
E
E
L
F
N
A
D
G
S
I
K
D
D
V
T
A
F
M
P
K
G
---
E
L
R
I
G
----
A
N
--
P
N
A
N
G
G
V
I
R
E
D
L
---
K
L
P
-
E
L
D
Q
Y
E
V
T
---
G
---
V
K
E
YGH
G
W
G
Q
V
E
A
P
R
A
L
G
A
Y
C
R
D
I
I
K
N
N
P
D
S
F
R
I
F
G
P
D
E
T
A
S
N
R
L
N
A
T
Y
E
V
T
D
K
Q
W
-
D
N
G
Y
L
S
G
L
-
V
-
D
E
H
M
A
V
T
G
Q
V
T
E
-
Q
L
S
E
H
Q
C
E
G
F
L
E
A
Y
L
L
T
G
R
-
H
G
----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
27
PsiBlast_CBE
84.86
50%
-9
- C9 -
-
3AI7
2
?
B:
[18-497]
-------------
S
E
E
A
L
E
G
V
D
K
Y
W
R
V
A
N
Y
L
S
I
G
Q
I
Y
L
R
S
N
P
L
M
K
E
P
F
T
R
E
D
V
K
H
R
L
V
G
H
W
G
T
T
P
G
L
N
F
L
-
I
G
H
I
N
R
F
I
A
-------
D
H
G
Q
N
T
V
I
I
M
G
P
G
H
G
G
P
A
G
T
S
Q
S
Y
L
D
G
T
Y
T
E
T
F
P
K
I
T
K
D
E
A
G
L
Q
K
F
F
R
Q
F
S
Y
P
G
G
I
P
S
H
F
A
P
-
E
T
P
G
S
I
H
E
G
G
E
L
G
Y
A
L
S
H
A
Y
G
A
I
M
D
N
-----------------
P
S
L
F
V
P
A
I
V
G
D
G
E
A
E
T
G
P
L
A
T
G
W
Q
S
N
K
L
V
N
P
R
T
D
G
I
V
L
P
I
L
H
L
N
G
Y
K
I
A
N
P
T
I
L
S
R
I
S
D
E
E
L
H
E
F
F
H
G
M
G
Y
E
P
Y
E
F
-
V
----
A
G
F
D
---
D
---
E
DHM
S
I
H
R
R
F
A
E
L
W
E
T
I
W
D
E
I
C
D
I
K
A
T
A
Q
---
T
D
N
V
H
R
P
F
Y
--
P
M
L
I
F
R
T
P
K
G
W
T
C
P
K
Y
I
D
G
K
K
T
E
G
S
W
R
S
H
Q
V
P
L
A
S
A
R
D
T
E
A
H
F
E
V
L
K
N
W
L
E
S
Y
K
P
E
E
L
F
D
A
N
G
A
V
K
D
D
V
L
A
F
M
P
K
G
---
E
L
R
I
G
----
A
N
--
P
N
A
N
G
G
V
I
R
N
D
L
---
K
L
P
-
N
L
E
D
Y
E
V
K
---
E
---
V
A
E
YGH
G
W
G
Q
L
E
A
T
R
T
L
G
A
Y
T
R
D
I
I
K
N
N
P
R
D
F
R
I
F
G
P
D
E
T
A
S
N
R
L
Q
A
S
Y
E
V
T
N
K
Q
W
D
A
G
-
Y
I
S
D
E
-
V
-
D
E
H
M
H
V
S
G
Q
V
V
E
-
Q
L
S
E
H
Q
M
E
G
F
L
E
A
Y
L
L
T
G
R
-
H
G
I
---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
21
PsiBlast_CBE
84.81
50%
-10
- C9 -
-
3AI7
2
?
H:
[18-497]
-------------
S
E
E
A
L
E
G
V
D
K
Y
W
R
V
A
N
Y
L
S
I
G
Q
I
Y
L
R
S
N
P
L
M
K
E
P
F
T
R
E
D
V
K
H
R
L
V
G
H
W
G
T
T
P
G
L
N
F
L
-
I
G
H
I
N
R
F
I
A
-------
D
H
G
Q
N
T
V
I
I
M
G
P
G
H
G
G
P
A
G
T
S
Q
S
Y
L
D
G
T
Y
T
E
T
F
P
K
I
T
K
D
E
A
G
L
Q
K
F
F
R
Q
F
S
Y
P
G
G
I
P
S
H
F
A
P
-
E
T
P
G
S
I
H
E
G
G
E
L
G
Y
A
L
S
H
A
Y
G
A
I
M
D
N
-----------------
P
S
L
F
V
P
A
I
V
G
D
G
E
A
E
T
G
P
L
A
T
G
W
Q
S
N
K
L
V
N
P
R
T
D
G
I
V
L
P
I
L
H
L
N
G
Y
K
I
A
N
P
T
I
L
S
R
I
S
D
E
E
L
H
E
F
F
H
G
M
G
Y
E
P
Y
E
F
-
V
----
A
G
F
D
---
D
---
E
DHM
S
I
H
R
R
F
A
E
L
W
E
T
I
W
D
E
I
C
D
I
K
A
T
A
Q
---
T
D
N
V
H
R
P
F
Y
--
P
M
L
I
F
R
T
P
K
G
W
T
C
P
K
Y
I
D
G
K
K
T
E
G
S
W
R
S
H
Q
V
P
L
A
S
A
R
D
T
E
A
H
F
E
V
L
K
N
W
L
E
S
Y
K
P
E
E
L
F
D
A
N
G
A
V
K
D
D
V
L
A
F
M
P
K
G
---
E
L
R
I
G
----
A
N
--
P
N
A
N
G
G
V
I
R
N
D
L
---
K
L
P
-
N
L
E
D
Y
E
V
K
---
E
---
V
A
E
YGH
G
W
G
Q
L
E
A
T
R
T
L
G
A
Y
T
R
D
I
I
K
N
N
P
R
D
F
R
I
F
G
P
D
E
T
A
S
N
R
L
Q
A
S
Y
E
V
T
N
K
Q
W
D
A
G
-
Y
I
S
D
E
-
V
-
D
E
H
M
H
V
S
G
Q
V
V
E
-
Q
L
S
E
H
Q
M
E
G
F
L
E
A
Y
L
L
T
G
R
-
H
G
I
---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
24
PsiBlast_CBE
84.76
50%
-8
- C9 -
-
3AI7
2
?
E:
[18-497]
-------------
S
E
E
A
L
E
G
V
D
K
Y
W
R
V
A
N
Y
L
S
I
G
Q
I
Y
L
R
S
N
P
L
M
K
E
P
F
T
R
E
D
V
K
H
R
L
V
G
H
W
G
T
T
P
G
L
N
F
L
-
I
G
H
I
N
R
F
I
A
-------
D
H
G
Q
N
T
V
I
I
M
G
P
G
H
G
G
P
A
G
T
S
Q
S
Y
L
D
G
T
Y
T
E
T
F
P
K
I
T
K
D
E
A
G
L
Q
K
F
F
R
Q
F
S
Y
P
G
G
I
P
S
H
F
A
P
-
E
T
P
G
S
I
H
E
G
G
E
L
G
Y
A
L
S
H
A
Y
G
A
I
M
D
N
-----------------
P
S
L
F
V
P
A
I
V
G
D
G
E
A
E
T
G
P
L
A
T
G
W
Q
S
N
K
L
V
N
P
R
T
D
G
I
V
L
P
I
L
H
L
N
G
Y
K
I
A
N
P
T
I
L
S
R
I
S
D
E
E
L
H
E
F
F
H
G
M
G
Y
E
P
Y
E
F
-
V
----
A
G
F
D
---
D
---
E
DHM
S
I
H
R
R
F
A
E
L
W
E
T
I
W
D
E
I
C
D
I
K
A
T
A
Q
---
T
D
N
V
H
R
P
F
Y
--
P
M
L
I
F
R
T
P
K
G
W
T
C
P
K
Y
I
D
G
K
K
T
E
G
S
W
R
S
H
Q
V
P
L
A
S
A
R
D
T
E
A
H
F
E
V
L
K
N
W
L
E
S
Y
K
P
E
E
L
F
D
A
N
G
A
V
K
D
D
V
L
A
F
M
P
K
G
---
E
L
R
I
G
----
A
N
--
P
N
A
N
G
G
V
I
R
N
D
L
---
K
L
P
-
N
L
E
D
Y
E
V
K
---
E
---
V
A
E
YGH
G
W
G
Q
L
E
A
T
R
T
L
G
A
Y
T
R
D
I
I
K
N
N
P
R
D
F
R
I
F
G
P
D
E
T
A
S
N
R
L
Q
A
S
Y
E
V
T
N
K
Q
W
D
A
G
-
Y
I
S
D
E
-
V
-
D
E
H
M
H
V
S
G
Q
V
V
E
-
Q
L
S
E
H
Q
M
E
G
F
L
E
A
Y
L
L
T
G
R
-
H
G
I
---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
6
PsiBlast_PDB
84.65
50%
-7
- C9 -
-
3AI7
2
?
A:
[18-497]
-------------
S
E
E
A
L
E
G
V
D
K
Y
W
R
V
A
N
Y
L
S
I
G
Q
I
Y
L
R
S
N
P
L
M
K
E
P
F
T
R
E
D
V
K
H
R
L
V
G
H
W
G
T
T
P
G
L
N
F
L
-
I
G
H
I
N
R
F
I
A
-------
D
H
G
Q
N
T
V
I
I
M
G
P
G
H
G
G
P
A
G
T
S
Q
S
Y
L
D
G
T
Y
T
E
T
F
P
K
I
T
K
D
E
A
G
L
Q
K
F
F
R
Q
F
S
Y
P
G
G
I
P
S
H
F
A
P
-
E
T
P
G
S
I
H
E
G
G
E
L
G
Y
A
L
S
H
A
Y
G
A
I
M
D
N
-----------------
P
S
L
F
V
P
A
I
V
G
D
G
E
A
E
T
G
P
L
A
T
G
W
Q
S
N
K
L
V
N
P
R
T
D
G
I
V
L
P
I
L
H
L
N
G
Y
K
I
A
N
P
T
I
L
S
R
I
S
D
E
E
L
H
E
F
F
H
G
M
G
Y
E
P
Y
E
F
-
V
----
A
G
F
D
---
D
---
E
D
H
M
S
I
H
R
R
F
A
E
L
W
E
T
I
W
D
E
I
C
D
I
K
A
T
A
Q
---
T
D
N
V
H
R
P
F
Y
--
P
M
L
I
F
R
T
P
K
G
W
T
C
P
K
Y
I
D
G
K
K
T
E
G
S
W
R
S
H
Q
V
P
L
A
S
A
R
D
T
E
A
H
F
E
V
L
K
N
W
L
E
S
Y
K
P
E
E
L
F
D
A
N
G
A
V
K
D
D
V
L
A
F
M
P
K
G
---
E
L
R
I
G
----
A
N
--
P
N
A
N
G
G
V
I
R
N
D
L
---
K
L
P
-
N
L
E
D
Y
E
V
K
---
E
---
V
A
E
YGH
G
W
G
Q
L
E
A
T
R
T
L
G
A
Y
T
R
D
I
I
K
N
N
P
R
D
F
R
I
F
G
P
D
E
T
A
S
N
R
L
Q
A
S
Y
E
V
T
N
K
Q
W
D
A
G
-
Y
I
S
D
E
-
V
-
D
E
H
M
H
V
S
G
Q
V
V
E
-
Q
L
S
E
H
Q
M
E
G
F
L
E
A
Y
L
L
T
G
R
-
H
G
I
---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
22
PsiBlast_CBE
84.37
50%
-7
- C9 -
-
3AI7
2
?
G:
[18-497]
-------------
S
E
E
A
L
E
G
V
D
K
Y
W
R
V
A
N
Y
L
S
I
G
Q
I
Y
L
R
S
N
P
L
M
K
E
P
F
T
R
E
D
V
K
H
R
L
V
G
H
W
G
T
T
P
G
L
N
F
L
-
I
G
H
I
N
R
F
I
A
-------
D
H
G
Q
N
T
V
I
I
M
G
P
G
H
G
G
P
A
G
T
S
Q
S
Y
L
D
G
T
Y
T
E
T
F
P
K
I
T
K
D
E
A
G
L
Q
K
F
F
R
Q
F
S
Y
P
G
G
I
P
S
H
F
A
P
-
E
T
P
G
S
I
H
E
G
G
E
L
G
Y
A
L
S
H
A
Y
G
A
I
M
D
N
-----------------
P
S
L
F
V
P
A
I
V
G
D
G
E
A
E
T
G
P
L
A
T
G
W
Q
S
N
K
L
V
N
P
R
T
D
G
I
V
L
P
I
L
H
L
N
G
Y
K
I
A
N
P
T
I
L
S
R
I
S
D
E
E
L
H
E
F
F
H
G
M
G
Y
E
P
Y
E
F
-
V
----
A
G
F
D
---
D
---
E
DHM
S
I
H
R
R
F
A
E
L
W
E
T
I
W
D
E
I
C
D
I
K
A
T
A
Q
---
T
D
N
V
H
R
P
F
Y
--
P
M
L
I
F
R
T
P
K
G
W
T
C
P
K
Y
I
D
G
K
K
T
E
G
S
W
R
S
H
Q
V
P
L
A
S
A
R
D
T
E
A
H
F
E
V
L
K
N
W
L
E
S
Y
K
P
E
E
L
F
D
A
N
G
A
V
K
D
D
V
L
A
F
M
P
K
G
---
E
L
R
I
G
----
A
N
--
P
N
A
N
G
G
V
I
R
N
D
L
---
K
L
P
-
N
L
E
D
Y
E
V
K
---
E
---
V
A
E
YGH
G
W
G
Q
L
E
A
T
R
T
L
G
A
Y
T
R
D
I
I
K
N
N
P
R
D
F
R
I
F
G
P
D
E
T
A
S
N
R
L
Q
A
S
Y
E
V
T
N
K
Q
W
D
A
G
-
Y
I
S
D
E
-
V
-
D
E
H
M
H
V
S
G
Q
V
V
E
-
Q
L
S
E
H
Q
M
E
G
F
L
E
A
Y
L
L
T
G
R
-
H
G
I
---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
23
PsiBlast_CBE
84.05
50%
-9
- C9 -
-
3AI7
2
?
F:
[18-497]
-------------
S
E
E
A
L
E
G
V
D
K
Y
W
R
V
A
N
Y
L
S
I
G
Q
I
Y
L
R
S
N
P
L
M
K
E
P
F
T
R
E
D
V
K
H
R
L
V
G
H
W
G
T
T
P
G
L
N
F
L
-
I
G
H
I
N
R
F
I
A
-------
D
H
G
Q
N
T
V
I
I
M
G
P
G
H
G
G
P
A
G
T
S
Q
S
Y
L
D
G
T
Y
T
E
T
F
P
K
I
T
K
D
E
A
G
L
Q
K
F
F
R
Q
F
S
Y
P
G
G
I
P
S
H
F
A
P
-
E
T
P
G
S
I
H
E
G
G
E
L
G
Y
A
L
S
H
A
Y
G
A
I
M
D
N
-----------------
P
S
L
F
V
P
A
I
V
G
D
G
E
A
E
T
G
P
L
A
T
G
W
Q
S
N
K
L
V
N
P
R
T
D
G
I
V
L
P
I
L
H
L
N
G
Y
K
I
A
N
P
T
I
L
S
R
I
S
D
E
E
L
H
E
F
F
H
G
M
G
Y
E
P
Y
E
F
-
V
----
A
G
F
D
---
D
---
E
DHM
S
I
H
R
R
F
A
E
L
W
E
T
I
W
D
E
I
C
D
I
K
A
T
A
Q
---
T
D
N
V
H
R
P
F
Y
--
P
M
L
I
F
R
T
P
K
G
W
T
C
P
K
Y
I
D
G
K
K
T
E
G
S
W
R
S
H
Q
V
P
L
A
S
A
R
D
T
E
A
H
F
E
V
L
K
N
W
L
E
S
Y
K
P
E
E
L
F
D
A
N
G
A
V
K
D
D
V
L
A
F
M
P
K
G
---
E
L
R
I
G
----
A
N
--
P
N
A
N
G
G
V
I
R
N
D
L
---
K
L
P
-
N
L
E
D
Y
E
V
K
---
E
---
V
A
E
YGH
G
W
G
Q
L
E
A
T
R
T
L
G
A
Y
T
R
D
I
I
K
N
N
P
R
D
F
R
I
F
G
P
D
E
T
A
S
N
R
L
Q
A
S
Y
E
V
T
N
K
Q
W
D
A
G
-
Y
I
S
D
E
-
V
-
D
E
H
M
H
V
S
G
Q
V
V
E
-
Q
L
S
E
H
Q
M
E
G
F
L
E
A
Y
L
L
T
G
R
-
H
G
I
---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
25
PsiBlast_CBE
83.99
50%
-7
- C9 -
-
3AI7
2
?
D:
[18-497]
-------------
S
E
E
A
L
E
G
V
D
K
Y
W
R
V
A
N
Y
L
S
I
G
Q
I
Y
L
R
S
N
P
L
M
K
E
P
F
T
R
E
D
V
K
H
R
L
V
G
H
W
G
T
T
P
G
L
N
F
L
-
I
G
H
I
N
R
F
I
A
-------
D
H
G
Q
N
T
V
I
I
M
G
P
G
H
G
G
P
A
G
T
S
Q
S
Y
L
D
G
T
Y
T
E
T
F
P
K
I
T
K
D
E
A
G
L
Q
K
F
F
R
Q
F
S
Y
P
G
G
I
P
S
H
F
A
P
-
E
T
P
G
S
I
H
E
G
G
E
L
G
Y
A
L
S
H
A
Y
G
A
I
M
D
N
-----------------
P
S
L
F
V
P
A
I
V
G
D
G
E
A
E
T
G
P
L
A
T
G
W
Q
S
N
K
L
V
N
P
R
T
D
G
I
V
L
P
I
L
H
L
N
G
Y
K
I
A
N
P
T
I
L
S
R
I
S
D
E
E
L
H
E
F
F
H
G
M
G
Y
E
P
Y
E
F
-
V
----
A
G
F
D
---
D
---
E
DHM
S
I
H
R
R
F
A
E
L
W
E
T
I
W
D
E
I
C
D
I
K
A
T
A
Q
---
T
D
N
V
H
R
P
F
Y
--
P
M
L
I
F
R
T
P
K
G
W
T
C
P
K
Y
I
D
G
K
K
T
E
G
S
W
R
S
H
Q
V
P
L
A
S
A
R
D
T
E
A
H
F
E
V
L
K
N
W
L
E
S
Y
K
P
E
E
L
F
D
A
N
G
A
V
K
D
D
V
L
A
F
M
P
K
G
---
E
L
R
I
G
----
A
N
--
P
N
A
N
G
G
V
I
R
N
D
L
---
K
L
P
-
N
L
E
D
Y
E
V
K
---
E
---
V
A
E
YGH
G
W
G
Q
L
E
A
T
R
T
L
G
A
Y
T
R
D
I
I
K
N
N
P
R
D
F
R
I
F
G
P
D
E
T
A
S
N
R
L
Q
A
S
Y
E
V
T
N
K
Q
W
D
A
G
-
Y
I
S
D
E
-
V
-
D
E
H
M
H
V
S
G
Q
V
V
E
-
Q
L
S
E
H
Q
M
E
G
F
L
E
A
Y
L
L
T
G
R
-
H
G
I
---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
26
PsiBlast_CBE
83.74
50%
-5
- C9 -
-
3AI7
2
?
C:
[18-497]
-------------
S
E
E
A
L
E
G
V
D
K
Y
W
R
V
A
N
Y
L
S
I
G
Q
I
Y
L
R
S
N
P
L
M
K
E
P
F
T
R
E
D
V
K
H
R
L
V
G
H
W
G
T
T
P
G
L
N
F
L
-
I
G
H
I
N
R
F
I
A
-------
D
H
G
Q
N
T
V
I
I
M
G
P
G
H
G
G
P
A
G
T
S
Q
S
Y
L
D
G
T
Y
T
E
T
F
P
K
I
T
K
D
E
A
G
L
Q
K
F
F
R
Q
F
S
Y
P
G
G
I
P
S
H
F
A
P
-
E
T
P
G
S
I
H
E
G
G
E
L
G
Y
A
L
S
H
A
Y
G
A
I
M
D
N
-----------------
P
S
L
F
V
P
A
I
V
G
D
G
E
A
E
T
G
P
L
A
T
G
W
Q
S
N
K
L
V
N
P
R
T
D
G
I
V
L
P
I
L
H
L
N
G
Y
K
I
A
N
P
T
I
L
S
R
I
S
D
E
E
L
H
E
F
F
H
G
M
G
Y
E
P
Y
E
F
-
V
----
A
G
F
D
---
D
---
E
DHM
S
I
H
R
R
F
A
E
L
W
E
T
I
W
D
E
I
C
D
I
K
A
T
A
Q
---
T
D
N
V
H
R
P
F
Y
--
P
M
L
I
F
R
T
P
K
G
W
T
C
P
K
Y
I
D
G
K
K
T
E
G
S
W
R
S
H
Q
V
P
L
A
S
A
R
D
T
E
A
H
F
E
V
L
K
N
W
L
E
S
Y
K
P
E
E
L
F
D
A
N
G
A
V
K
D
D
V
L
A
F
M
P
K
G
---
E
L
R
I
G
----
A
N
--
P
N
A
N
G
G
V
I
R
N
D
L
---
K
L
P
-
N
L
E
D
Y
E
V
K
---
E
---
V
A
E
YGH
G
W
G
Q
L
E
A
T
R
T
L
G
A
Y
T
R
D
I
I
K
N
N
P
R
D
F
R
I
F
G
P
D
E
T
A
S
N
R
L
Q
A
S
Y
E
V
T
N
K
Q
W
D
A
G
-
Y
I
S
D
E
-
V
-
D
E
H
M
H
V
S
G
Q
V
V
E
-
Q
L
S
E
H
Q
M
E
G
F
L
E
A
Y
L
L
T
G
R
-
H
G
I
---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
97
HHSearch
83.01
49%
-5
- C9 -
-
3AI7
2
?
C:
[16-510]
-----------
P
V
S
E
E
A
L
E
G
V
D
K
Y
W
R
V
A
N
Y
L
S
I
G
Q
I
Y
L
R
S
N
P
L
M
K
E
P
F
T
R
E
D
V
K
H
R
L
V
G
H
W
G
T
T
P
G
L
N
F
L
-
I
G
H
I
N
R
F
I
A
-------
D
H
G
Q
N
T
V
I
I
M
G
P
G
H
G
G
P
A
G
T
S
Q
S
Y
L
D
G
T
Y
T
E
T
F
P
K
I
T
K
D
E
A
G
L
Q
K
F
F
R
Q
F
S
Y
P
G
G
I
P
S
H
F
A
P
-
E
T
P
G
S
I
H
E
G
G
E
L
G
Y
A
L
S
H
A
Y
G
A
I
M
D
N
-----------------
P
S
L
F
V
P
A
I
V
G
D
G
E
A
E
T
G
P
L
A
T
G
W
Q
S
N
K
L
V
N
P
R
T
D
G
I
V
L
P
I
L
H
L
N
G
Y
K
I
A
N
P
T
I
L
S
R
I
S
D
E
E
L
H
E
F
F
H
G
M
G
Y
E
P
Y
-
E
F
V
----
A
G
F
D
DED
H
---
M
---
S
I
H
R
R
F
A
E
L
W
E
T
I
W
D
E
I
C
D
I
K
A
T
A
Q
T
D
---
N
V
H
R
P
F
Y
--
P
M
L
I
F
R
T
P
K
G
W
T
C
P
K
Y
I
D
G
K
K
T
E
G
S
W
R
S
H
Q
V
P
L
A
S
A
R
D
T
E
A
H
F
E
V
L
K
N
W
L
E
S
Y
K
P
E
E
L
F
D
A
N
G
A
V
K
D
D
V
L
A
F
M
P
K
G
---
E
L
R
I
G
----
A
N
--
P
N
A
N
G
G
V
I
R
N
D
L
---
K
L
P
-
N
L
E
D
Y
E
V
K
---
E
VAE
Y
G
H
---
G
W
G
Q
L
E
A
T
R
T
L
G
A
Y
T
R
D
I
I
K
N
N
P
R
D
F
R
I
F
G
P
D
E
T
A
S
N
R
L
Q
A
S
Y
E
V
T
N
K
Q
W
-
D
A
-
G
Y
I
S
D
E
V
-
D
E
H
M
H
V
S
G
Q
V
V
E
-
Q
L
S
E
H
Q
M
E
G
F
L
E
A
Y
L
L
T
G
R
-
H
G
I
W
S
S
Y
E
S
F
V
H
V
I
D
S
--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
120
Fugue
79.80
48%
30
- C9 -
-
3AHC
13
?
A:
[25-826]
VIGTPWQKL
D
R
P
V
S
E
E
A
I
E
G
M
D
K
Y
W
R
V
T
N
Y
M
S
I
G
Q
I
Y
L
R
S
N
P
L
M
K
E
P
F
T
R
D
D
V
K
H
R
L
V
G
H
W
G
T
T
P
G
L
N
F
L
-
L
A
H
I
N
R
L
I
A
-------
D
H
Q
Q
N
T
V
F
I
M
G
P
G
H
G
G
P
A
G
T
S
Q
S
Y
V
D
G
T
Y
T
E
Y
Y
P
N
I
T
K
D
E
A
G
L
Q
K
F
F
R
Q
F
S
Y
P
G
G
I
P
S
H
F
A
P
-
E
T
P
G
S
I
H
E
G
G
E
L
G
Y
A
L
S
H
A
Y
G
A
V
M
N
N
-----------------
P
S
L
F
V
P
C
I
I
G
D
G
E
A
E
T
G
P
L
A
T
G
W
Q
S
N
K
L
V
N
P
R
T
D
G
I
V
L
P
I
L
H
L
N
G
Y
K
I
A
N
P
T
I
L
A
R
I
S
D
E
E
L
H
D
F
F
R
G
M
G
Y
H
P
Y
-
E
-
F
V
A
GF
D
N
E
D
---
H
---
M
---
S
I
H
R
R
F
A
E
L
F
E
T
I
F
D
E
I
C
D
I
K
A
A
A
Q
---
T
D
D
M
T
R
P
F
Y
--
P
M
L
I
F
R
T
P
K
G
W
T
C
P
K
F
I
D
G
K
K
T
E
G
S
W
R
A
H
Q
V
P
L
A
S
A
R
D
T
E
E
H
F
E
V
L
K
G
W
M
E
S
Y
K
P
E
E
L
F
N
A
D
G
S
I
K
D
D
V
T
A
F
M
P
K
G
---
E
L
R
I
G
----
A
N
--
P
N
A
N
G
G
V
I
R
E
D
L
---
K
L
P
-
E
L
D
Q
Y
E
V
T
---
G
---
V
K
E
YGH
G
W
G
Q
V
E
A
P
R
A
L
G
A
Y
C
R
D
I
I
K
N
N
P
D
S
F
R
I
F
G
P
D
E
T
A
S
N
R
L
N
A
T
Y
E
V
T
D
K
Q
W
-
D
N
-
G
Y
L
S
G
-
L
V
D
E
H
M
A
V
T
G
Q
V
T
E
-
Q
L
S
E
H
Q
C
E
G
F
L
E
A
Y
L
L
T
G
R
-
H
G
I
W
S
S
Y
E
S
F
V
H
V
I
D
S
M
L
N
Q
H
A
K
W
L
E
A
T
V
R
EIPWRKPISSVNLLVSSHVWRQDHNGFSHQDPG
V
T
S
L
L
I
N
K
TFNNDHV
T
N
I
Y
F
ATD
A
N
M
L
L
A
I
S
E
K
C
F
K
STN
K
I
N
A
I
F
A
G
K
Q
P
A
P
T
W
V
T
L
D
E
A
R
A
E
L
E
A
GAAEWKWASNAENNDEVQ
V
V
L
A
S
A
G
D
V
P
T
Q
E
L
M
A
A
S
D
A
L
N
K
M
G
I
K
F
K
V
V
N
V
V
DLLKLQSRENNDEALT
D
E
E
F
T
E
L
FTAD
K
P
V
L
F
A
Y
HSY
A
Q
D
V
R
G
L
I
Y
DRPNHDN
F
H
V
V
G
YKEQGSTTT
P
F
D
M
V
R
V
N
DMD
R
Y
A
L
Q
A
A
A
L
K
L
I
DADKY
A
D
K
I
D
E
L
N
A
F
R
K
K
A
F
Q
F
A
V
D
NGYDI
P
E
F
T
D
WVYPDV
96
HHSearch
79.14
49%
24
- C9 -
-
3AHC
8
?
A:
[36-530]
-----------
P
V
S
E
E
A
I
E
G
M
D
K
Y
W
R
V
T
N
Y
M
S
I
G
Q
I
Y
L
R
S
N
P
L
M
K
E
P
F
T
R
D
D
V
K
H
R
L
V
G
H
W
G
T
T
P
G
L
N
F
L
-
L
A
H
I
N
R
L
I
A
D
------
H
Q
Q
N
T
V
F
-
I
M
G
P
G
H
G
G
P
A
G
T
S
Q
S
Y
V
D
G
T
Y
T
E
Y
Y
P
N
I
T
K
D
E
A
G
L
Q
K
F
F
R
Q
F
S
Y
P
G
G
I
P
S
H
F
A
P
-
E
T
P
G
S
I
H
E
G
G
E
L
G
Y
A
L
S
H
A
Y
G
A
V
M
N
N
-----------------
P
S
L
F
V
P
C
I
I
G
D
G
E
A
E
T
G
P
L
A
T
G
W
Q
S
N
K
L
V
N
P
R
T
D
G
I
V
L
P
I
L
H
L
N
G
Y
K
I
A
N
P
T
I
L
A
R
I
S
D
E
E
L
H
D
F
F
R
G
M
G
Y
H
P
Y
-
E
F
V
----
A
G
F
D
---
N
ED
H
M
---
S
I
H
R
R
F
A
E
L
F
E
T
I
F
D
E
I
C
D
I
K
A
A
A
Q
T
D
-----
D
M
T
R
P
F
Y
P
M
L
I
F
R
T
P
K
G
W
T
C
P
K
F
I
D
G
K
K
T
E
G
S
W
R
A
H
Q
V
P
L
A
S
A
R
D
T
E
E
H
F
E
V
L
K
G
W
M
E
S
Y
K
P
E
E
L
F
N
A
D
G
S
I
K
D
D
V
T
A
F
M
P
K
G
---
E
L
R
I
G
----
A
N
--
P
N
A
N
G
G
V
I
R
E
D
L
---
K
L
P
-
E
L
D
Q
Y
E
V
T
GVK
E
---
Y
G
H
---
G
W
G
Q
V
E
A
P
R
A
L
G
A
Y
C
R
D
I
I
K
N
N
P
D
S
F
R
I
F
G
P
D
E
T
A
S
N
R
L
N
A
T
Y
E
V
T
D
K
Q
W
-
D
N
-
G
Y
L
S
G
-
L
V
D
E
H
M
A
V
T
G
Q
V
T
E
-
Q
L
S
E
H
Q
C
E
G
F
L
E
A
Y
L
L
T
G
R
-
H
G
I
W
S
S
Y
E
S
F
V
H
V
I
D
S
--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
112
HHSearch
51.42
20%
6
- C9 -
-
3RIM
2
TKT_MYCTU
A:
[28-471]
------------------------------------------
D
T
I
R
V
L
A
A
D
A
V
Q
K
V
G
N
G
H
P
G
T
A
M
S
L
A
P
L
A
Y
T
L
F
Q
R
T
M
R
H
D
PSDTH
W
L
G
R
D
R
F
-
V
L
S
A
G
H
S
S
L
T
L
Y
I
Q
L
Y
L
G
G
F
G
------
L
E
L
S
D
--
I
E
S
-
L
R
T
W
G
S
--
K
T
P
G
H
P
E
F
R
H
T
P
G
V
E
I
T
T
G
P
L
G
Q
G
L
A
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A
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----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------